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List of works by David Colcher

A pretherapy biodistribution and dosimetry study of indium-111-radiolabeled trastuzumab in patients with human epidermal growth factor receptor 2-overexpressing breast cancer

scientific article

A series of anti-CEA/anti-DOTA bispecific antibody formats evaluated for pre-targeting: comparison of tumor uptake and blood clearance

scientific article published on 21 November 2012

A transgene-encoded cell surface polypeptide for selection, in vivo tracking, and ablation of engineered cells ⬇️

scientific article published on June 7, 2011

A versatile bifunctional chelate for radiolabeling humanized anti-CEA antibody with In-111 and Cu-64 at either thiol or amino groups: PET imaging of CEA-positive tumors with whole antibodies

scientific article published on 8 November 2007

An Engineered Cell Surface Polypeptide for Selection, Tracking and Ablation of Genetically Modified Hematopoietically Derived Cells Based on Human EGFR. ⬇️

scholarly article

Biodistribution and tumor imaging of an anti-CEA single-chain antibody-albumin fusion protein

scientific article

Combined radioimmunotherapy and chemotherapy of breast tumors with Y-90-labeled anti-Her2 and anti-CEA antibodies with taxol

scientific article published on September 2005

Combining adoptive cellular and immunocytokine therapies to improve treatment of B-lineage malignancy

scientific article published on March 2007

Copper-64-labeled daratumumab as a PET/CT imaging tracer for multiple myeloma

scientific article published on 4 January 2018

Development and application of CD19-specific T cells for adoptive immunotherapy of B cell malignancies

scientific article published in July 2004

Diagnostic PET Imaging of Mammary Microcalcifications Using 64Cu-DOTA-Alendronate in a Rat Model of Breast Cancer

scientific article

Effective Targeting of TAG72 Peritoneal Ovarian Tumors via Regional Delivery of CAR-Engineered T Cells

scientific article published on 19 November 2018

Functional imaging of human epidermal growth factor receptor 2-positive metastatic breast cancer using (64)Cu-DOTA-trastuzumab PET.

scientific article

Humanization of the anti-CEA T84.66 antibody based on crystal structure data

scientific article

Identifying CD38+ cells in patients with multiple myeloma: first-in-human imaging using copper-64-labeled daratumumab

scientific article published on 01 October 2020

Imaging glioma extent with 131I-TM-601.

scientific article

ImmunoPET, [64Cu]Cu-DOTA-Anti-CD33 PET-CT, Imaging of an AML Xenograft Model

scientific article published on 23 September 2019

Improved biodistribution and radioimmunoimaging with poly(ethylene glycol)-DOTA-conjugated anti-CEA diabody

scientific article published on January 2006

Improved targeting of an anti-TAG-72 antibody drug conjugate for the treatment of ovarian cancer

scientific article published on 05 May 2020

In vivo imaging of transplanted islets with 64Cu-DO3A-VS-Cys40-Exendin-4 by targeting GLP-1 receptor

scientific article published on 14 July 2011

Intratumoral immunocytokine treatment results in enhanced antitumor effects

scientific article published on 26 April 2008

Low Dose Focused Ultrasound Induces Enhanced Tumor Accumulation of Natural Killer Cells

scientific article

Mechanically interlocked functionalization of monoclonal antibodies.

scientific article published on 20 April 2018

Monodispersed DOTA-PEG-conjugated anti-TAG-72 diabody has low kidney uptake and high tumor-to-blood ratios resulting in improved 64Cu PET.

scientific article published on 16 June 2010

PET imaging of 64Cu-DOTA-scFv-anti-PSMA lipid nanoparticles (LNPs): Enhanced tumor targeting over anti-PSMA scFv or untargeted LNPs

scientific article published on 17 January 2017

PET of Adoptively Transferred Chimeric Antigen Receptor T Cells with 89Zr-Oxine

scientific article published on 04 May 2018

Phase I Study of Yttrium-90 Labeled ANTI-CD25 (aTac) Monoclonal Antibody PLUS BEAM for Autologous Hematopoietic CELL Transplantation (AHCT) in Patients with Mature T-CELL NON-Hodgkin Lymphoma, the "a-TAC-BEAM Regimen" ⬇️

scholarly article

Phase I Study of Yttrium-90 Radiolabeled M5A Anti-Carcinoembryonic Antigen Humanized Antibody in Patients with Advanced Carcinoembryonic Antigen Producing Malignancies

scientific article published on 07 January 2020

Phase I single-dose study of intracavitary-administered iodine-131-TM-601 in adults with recurrent high-grade glioma

scientific article

Phase I/II Trial of Anticarcinoembryonic Antigen Radioimmunotherapy, Gemcitabine, and Hepatic Arterial Infusion of Fluorodeoxyuridine Postresection of Liver Metastasis for Colorectal Carcinoma.

scientific article published in September 2017

Pilot trial evaluating an 123I-labeled 80-kilodalton engineered anticarcinoembryonic antigen antibody fragment (cT84.66 minibody) in patients with colorectal cancer

scientific article published in August 2004

Potent immunomodulatory effects of an anti-CEA-IL-2 immunocytokine on tumor therapy and effects of stereotactic radiation

scientific article published on 14 February 2020

Preclinical Efficacy of Campthothecin-Polymer Conjugate (IT-101) in Human Burkitt Lymphoma Bearing Mice. ⬇️

scholarly article

Preclinical results of camptothecin-polymer conjugate (IT-101) in multiple human lymphoma xenograft models

scientific article published on 23 June 2009

Quantitative serial imaging of an 124I anti-CEA monoclonal antibody in tumor-bearing mice

scientific article

Quantitative, Simultaneous PET/MRI for Intratumoral Imaging with an MRI-Compatible PET Scanner ⬇️

scientific article published on June 1, 2012

Radioiodinated versus radiometal-labeled anti-carcinoembryonic antigen single-chain Fv-Fc antibody fragments: optimal pharmacokinetics for therapy

scientific article published on January 2007

Rapid and efficient production of radiolabeled antibody conjugates using vacuum diafiltration guided by mathematical modeling

scientific article

Serial Diffusion MRI to Monitor and Model Treatment Response of the Targeted Nanotherapy CRLX101 ⬇️

scientific article published on March 26, 2013

Single molecular weight discrete PEG compounds: emerging roles in molecular diagnostics, imaging and therapeutics ⬇️

scientific article published on May 1, 2013

Site specific discrete PEGylation of (124)I-labeled mCC49 Fab' fragments improves tumor MicroPET/CT imaging in mice

scientific article

Site-specific conjugation of monodispersed DOTA-PEGn to a thiolated diabody reveals the effect of increasing peg size on kidney clearance and tumor uptake with improved 64-copper PET imaging

scientific article

Synthesis, positron emission tomography imaging, and therapy of diabody targeted drug lipid nanoparticles in a prostate cancer murine model

scientific article

TAG-72 targeted α-radionuclide therapy of ovarian cancer using actinium-225 labeled DOTAylated-huCC49 antibody

scientific article published on 03 July 2020

Tailoring the pharmacokinetics and positron emission tomography imaging properties of anti-carcinoembryonic antigen single-chain Fv-Fc antibody fragments.

scientific article

Template-Catalyzed, Disulfide Conjugation of Monoclonal Antibodies Using a Natural Amino Acid Tag

scientific article published on 25 May 2018

The Novel De-Immunized Anti-CD20-IL-2 Immunocytokine DI-Leu16-IL-2 Is Effective in SCID Mice Bearing Rituximab-Resistant Human Lymphoma Xenografts. ⬇️

scholarly article

Tumor Uptake of 64Cu-DOTA-Trastuzumab in Patients with Metastatic Breast Cancer.

scientific article published on 21 June 2017

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