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List of works by Marianne Thoresen

A closed-circuit neonatal xenon delivery system: a technical and practical neuroprotection feasibility study in newborn pigs

scientific article published in August 2009

A comparison of cooling methods used in therapeutic hypothermia for perinatal asphyxia

scientific article published on 07 June 2010

A neonatal piglet model of intraventricular hemorrhage and posthemorrhagic ventricular dilation

scientific article published in August 2007

Adding 5 h delayed xenon to delayed hypothermia treatment improves long-term function in neonatal rats surviving to adulthood

scientific article published on 11 March 2015

Amplitude-Integrated Electroencephalography Improves the Identification of Infants with Encephalopathy for Therapeutic Hypothermia and Predicts Neurodevelopmental Outcomes at 2 Years of Age.

scientific article published on 23 May 2017

Analysis of neuronal, glial, endothelial, axonal and apoptotic markers following moderate therapeutic hypothermia and anesthesia in the developing piglet brain

scientific article published on 9 October 2007

Animal research has been essential to saving babies' lives

scientific article published on 24 June 2014

Animal studies of neonatal hypothermic neuroprotection have translated well in to practice

scientific article published on 27 April 2015

Assessment of brain tissue injury after moderate hypothermia in neonates with hypoxic-ischaemic encephalopathy: a nested substudy of a randomised controlled trial

scientific article

Attention and visuo-spatial function in children without cerebral palsy who were cooled for neonatal encephalopathy: a case-control study

scientific article published on 29 March 2019

Brain imaging in cooled encephalopathic neonates does not differ between four and 11 days after birth

scientific article published on 24 April 2015

Brain wave recovery predicts outcome after cardiac arrest.

scientific article published on 29 November 2012

Cerebral Resistance Index is less predictive in hypothermic encephalopathic newborns ⬇️

scientific article published on May 18, 2011

Closed circuit xenon delivery for 72h in neonatal piglets following hypoxic insult using an ambient pressure automated control system: Development, technical evaluation and pulmonary effects

scientific article published on 21 January 2020

Combined effect of hypothermia and caspase-2 gene deficiency on neonatal hypoxic-ischemic brain injury

scientific article published on 9 February 2012

Combined treatment of xenon and hypothermia in newborn rats--additive or synergistic effect?

scientific article

Combining two good treatments makes it worse

scientific article published on 17 April 2018

Comparison of Bayley-2 and Bayley-3 scores at 18 months in term infants following neonatal encephalopathy and therapeutic hypothermia

scientific article

Cooling combined with immediate or delayed xenon inhalation provides equivalent long-term neuroprotection after neonatal hypoxia-ischemia

scientific article published on 14 January 2009

Cooling neonates who do not fulfil the standard cooling criteria - short- and long-term outcomes

scientific article

Decorin and colchicine as potential treatments for post-haemorrhagic ventricular dilatation in a neonatal rat model

scientific article published on 23 June 2011

Delayed hypothermia as selective head cooling or whole body cooling does not protect brain or body in newborn pig subjected to hypoxia-ischemia

scientific article

Determinants of outcomes after head cooling for neonatal encephalopathy.

scientific article

Development of amplitude-integrated electroencephalography and interburst interval in the rat.

scientific article published in January 2009

Do drugs that block transforming growth factor beta reduce posthaemorrhagic ventricular dilatation in a neonatal rat model?

scientific article published on 9 July 2008

Does head cooling with mild systemic hypothermia affect requirement for blood pressure support?

scientific article published in March 2009

Early deterioration of cerebrospinal fluid dynamics in a neonatal piglet model of intraventricular hemorrhage and posthemorrhagic ventricular dilation ⬇️

scientific article published on September 28, 2012

Effect of cardiac compressions and hypothermia treatment on cardiac troponin I in newborns with perinatal asphyxia

scientific article published on 12 July 2013

Effect of hypothermia on amplitude-integrated electroencephalogram in infants with asphyxia

scientific article

Effects of hypothermia for perinatal asphyxia on childhood outcomes

scientific article published in July 2014

Effects of xenon and hypothermia on cerebrovascular pressure reactivity in newborn global hypoxic-ischemic pig model

scientific article published on 31 July 2013

Environmental cooling of the newborn pig brain during whole‐body cooling ⬇️

scientific article published on January 1, 2011

Equipotent subanesthetic concentrations of sevoflurane and xenon preventing cold-stimulated vocalization of neonatal rats.

scientific article published in December 2014

Factors associated with permanent hearing impairment in infants treated with therapeutic hypothermia.

scientific article published on 23 July 2013

Fentanyl Induces Cerebellar Internal Granular Cell Layer Apoptosis in Healthy Newborn Pigs.

scientific article

Head cooling with mild systemic hypothermia in anesthetized piglets is neuroprotective

scientific article published in January 2003

Heart rate response to therapeutic hypothermia in infants with hypoxic-ischaemic encephalopathy

scientific article published on 28 June 2016

Hypothermia Does Not Reverse Cellular Responses Caused by Lipopolysaccharide in Neonatal Hypoxic-Ischaemic Brain Injury.

scientific article published on 12 June 2015

Hypothermia Is Neuroprotective after Severe Hypoxic-Ischaemic Brain Injury in Neonatal Rats Pre-Exposed to PAM3CSK4

scientific article published on 01 June 2018

Hypothermia and other treatment options for neonatal encephalopathy: an executive summary of the Eunice Kennedy Shriver NICHD workshop

scientific article

Hypothermia and perinatal asphyxia: executive summary of the National Institute of Child Health and Human Development workshop

scientific article

Hypothermia is not neuroprotective after infection-sensitized neonatal hypoxic-ischemic brain injury.

scientific article

Hypothermia: An Evolving Treatment for Neonatal Hypoxic Ischemic Encephalopathy

scientific article published on 01 March 2008

Hypothermic Neuronal Rescue from Infection-Sensitised Hypoxic-Ischaemic Brain Injury Is Pathogen Dependent

scientific article published on 14 April 2017

Immediate Hypothermia Is Not Neuroprotective After Severe Hypoxia-Ischemia and Is Deleterious When Delayed by 12 Hours in Neonatal Rats ⬇️

scientific article published on September 20, 2012

Immediate Hypothermia Reduces Cardiac Troponin I After Hypoxic-Ischemic Encephalopathy in Newborn Pigs ⬇️

scientific article published on October 1, 2011

Increased Inspired Oxygen in the First Hours of Life is Associated with Adverse Outcome in Newborns Treated for Perinatal Asphyxia with Therapeutic Hypothermia ⬇️

scientific article published on April 18, 2012

Lactate dehydrogenase in hypothermia‐treated newborn infants with hypoxic‐ischaemic encephalopathy ⬇️

scientific article published on July 27, 2012

Lactate dehydrogenase predicts hypoxic ischaemic encephalopathy in newborn infants: a preliminary study

scientific article published on 19 March 2010

Less severe cerebral palsy outcomes in infants treated with therapeutic hypothermia

scientific article published on 3 August 2015

Liver enzymes cannot be used to predict liver damage after global hypoxia-ischemia in a neonatal pig model.

scientific article published on 29 April 2009

Major concerns about late hypothermia study

scientific article published on 28 November 2018

Mild hypothermia and the distribution of cerebral lesions in neonates with hypoxic-ischemic encephalopathy.

scientific article published in October 2005

Minimal systemic hypothermia combined with selective head cooling evaluated in a pig model of hypoxia-ischemia

scientific article published on 9 February 2015

Moderate hypothermia to treat perinatal asphyxial encephalopathy

scientific article published in October 2009

Monitoring of cerebral blood flow during hypoxia-ischemia and resuscitation in the neonatal rat using laser speckle imaging

scientific article

Motor performance and cognitive correlates in children cooled for neonatal encephalopathy without cerebral palsy at school age

scientific article published on 09 April 2019

Neither xenon nor fentanyl induces neuroapoptosis in the newborn pig brain

scientific article published in August 2013

Neonatal Systemic Inflammation Induces Inflammatory Reactions and Brain Apoptosis in a Pathogen-Specific Manner.

scientific article published on 23 December 2017

Neonatal seizures: magnetic resonance imaging adds value in the diagnosis and prediction of neurodisability

scientific article published on 26 February 2014

Neurological outcomes at 18 months of age after moderate hypothermia for perinatal hypoxic ischaemic encephalopathy: synthesis and meta-analysis of trial data

scientific article

Neuroprotection after infection-sensitized neonatal hypoxic-ischemic brain injury.

scientific article

Phase 1 trial of prevention of hydrocephalus after intraventricular hemorrhage in newborn infants by drainage, irrigation, and fibrinolytic therapy

scientific article published in April 2003

Preliminary evaluation of a novel intraparenchymal capacitive intracranial pressure monitor

scientific article published on 27 May 2011

Randomized clinical trial of prevention of hydrocephalus after intraventricular hemorrhage in preterm infants: brain-washing versus tapping fluid

scientific article published on 2 April 2007

Rectal temperature in the first five hours after hypoxia-ischemia critically affects neuropathological outcomes in neonatal rats

scientific article published on 01 November 2017

Reduced infancy and childhood epilepsy following hypothermia-treated neonatal encephalopathy

scientific article published on 29 September 2017

Respiratory sinus arrhythmia stabilizes mean arterial blood pressure at high-frequency interval in healthy humans

scientific article published on 9 November 2014

Resuscitation with 100% oxygen increases injury and counteracts the neuroprotective effect of therapeutic hypothermia in the neonatal rat.

scientific article published on 11 January 2012

School-age outcomes of children without cerebral palsy cooled for neonatal hypoxic-ischaemic encephalopathy in 2008-2010

scientific article published on 29 April 2019

Secretions from placenta, after hypoxia/reoxygenation, can damage developing neurones of brain under experimental conditions.

scientific article published on 10 May 2014

Sedation management during therapeutic hypothermia for neonatal encephalopathy: atropine premedication for endotracheal intubation causes a prolonged increase in heart rate.

scientific article published on 22 July 2014

Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial

scientific article published in February 2005

Serum gentamicin concentrations in encephalopathic infants are not affected by therapeutic hypothermia.

scientific article published in July 2009

Seven- to eight-year follow-up of the CoolCap trial of head cooling for neonatal encephalopathy ⬇️

scientific article published on December 21, 2011

Should therapeutic hypothermia be offered to babies with mild neonatal encephalopathy in the first 6 h after birth?

scientific article published on 16 January 2019

Significant selective head cooling can be maintained long-term after global hypoxia ischemia in newborn piglets

scientific article published in April 2002

Start cooling as soon as possible.

scientific article published on 21 January 2019

The Effects of Xenon Gas Inhalation on Neuropathology in a Placental-Induced Brain Injury Model in Neonates: A Pilot Study

scientific article published on 18 July 2020

The TOBY Study. Whole body hypothermia for the treatment of perinatal asphyxial encephalopathy: a randomised controlled trial

scientific article published on 30 April 2008

The effect of resuscitation in 100% oxygen on brain injury in a newborn rat model of severe hypoxic-ischaemic encephalopathy

scientific article published on 20 August 2015

The feasibility of using a portable xenon delivery device to permit earlier xenon ventilation with therapeutic cooling of neonates during ambulance retrieval.

scientific article published in June 2015

The pathogenesis of neonatal post-hemorrhagic hydrocephalus

scientific article published in July 2004

Therapeutic Hypothermia Changes the Prognostic Value of Clinical Evaluation of Neonatal Encephalopathy

scientific article published on 24 October 2007

Therapeutic Hypothermia in Neonatal Hypoxic-Ischemic Encephalopathy

scientific article published on 14 January 2019

Therapeutic hypothermia delays the C-reactive protein response and suppresses white blood cell and platelet count in infants with neonatal encephalopathy

scientific article published on 27 June 2014

Therapeutic hypothermia for hypoxic-ischaemic encephalopathy in the newborn infant

scientific article

Therapeutic hypothermia in neonates. Review of current clinical data, ILCOR recommendations and suggestions for implementation in neonatal intensive care units

scientific article

Therapeutic hypothermia translates from ancient history in to practice.

scientific article published on 27 September 2016

Time is brain: starting therapeutic hypothermia within three hours after birth improves motor outcome in asphyxiated newborns

scientific article

Treatment temperature and insult severity influence the neuroprotective effects of therapeutic hypothermia.

scientific article published on 21 March 2016

Validation of a neuropathology score using quantitative methods to evaluate brain injury in a pig model of hypoxia ischaemia

scientific article published on 18 April 2014

Variability and sex-dependence of hypothermic neuroprotection in a rat model of neonatal hypoxic-ischaemic brain injury: a single laboratory meta-analysis

scientific article published on 02 July 2020

Why results from Bayesian statistical analyses of clinical trials with a strong prior and small sample sizes may be misleading The case of the NICHD Neonatal Research Network Late Hypothermia Trial

scientific article published on 11 April 2019

Xenon Combined with Therapeutic Hypothermia Is Not Neuroprotective after Severe Hypoxia-Ischemia in Neonatal Rats

scientific article

Xenon and hypothermia combine additively, offering long-term functional and histopathologic neuroprotection after neonatal hypoxia/ischemia

scientific article

Xenon depresses aEEG background voltage activity whilst maintaining cardiovascular stability in sedated healthy newborn pigs.

scientific article published on 21 February 2016

Xenon enhances hypothermic neuroprotection in asphyxiated newborn pigs

scientific article

Xenon offers stable haemodynamics independent of induced hypothermia after hypoxia–ischaemia in newborn pigs ⬇️

scientific article published on December 13, 2011

Xenon provides short-term neuroprotection in neonatal rats when administered after hypoxia-ischemia

scientific article

Xenon ventilation during therapeutic hypothermia in neonatal encephalopathy: a feasibility study

scientific article published in May 2014

Xenon/hypothermia neuroprotection regimes in spontaneously breathing neonatal rats after hypoxic-ischemic insult: the respiratory and sedative effects

scientific article

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