List of works - Shinji Makino

A new comprehensive method for detection of livestock-related pathogenic viruses using a target enrichment system

scientific article published on 6 December 2017

A novel defective recombinant porcine enterovirus G virus carrying a porcine torovirus papain-like cysteine protease gene and a putative anti-apoptosis gene in place of viral structural protein genes

article

A single-cycle replicable Rift Valley fever phlebovirus vaccine carrying a mutated NSs confers full protection from lethal challenge in mice

scientific article published in Scientific Reports

A structural analysis of M protein in coronavirus assembly and morphology

scientific article

A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein

scientific article published on 18 October 2009

Alphacoronavirus transmissible gastroenteritis virus nsp1 protein suppresses protein translation in mammalian cells and in cell-free HeLa cell extracts but not in rabbit reticulocyte lysate

scientific article

Characterization of N protein self-association in coronavirus ribonucleoprotein complexes

scientific article published on December 2003

Characterization of Rift Valley fever virus transcriptional terminations.

scientific article

Characterization of synthetic Chikungunya viruses based on the consensus sequence of recent E1-226V isolates

scientific article

Chimeric coronavirus-like particles carrying severe acute respiratory syndrome coronavirus (SCoV) S protein protect mice against challenge with SCoV

scientific article

Coronavirus nonstructural protein 1: Common and distinct functions in the regulation of host and viral gene expression

scientific article published on 26 November 2014

Correction: Rapid Accumulation of Virulent Rift Valley Fever Virus in Mice from an Attenuated Virus Carrying a Single Nucleotide Substitution in the M RNA.

scientific article published on 13 April 2010

Cyclosporin A inhibits the replication of diverse coronaviruses

scientific article

Dembo polymerase chain reaction technique for detection of bovine abortion, diarrhea, and respiratory disease complex infectious agents in potential vectors and reservoirs

scientific article published on 28 December 2017

Development of a novel, single-cycle replicable rift valley Fever vaccine

scientific article

Differential virological and immunological outcome of severe acute respiratory syndrome coronavirus infection in susceptible and resistant transgenic mice expressing human angiotensin-converting enzyme 2.

scientific article published on 18 March 2009

Dual functions of Rift Valley fever virus NSs protein: inhibition of host mRNA transcription and post-transcriptional downregulation of protein kinase PKR.

scientific article

Exogenous ACE2 expression allows refractory cell lines to support severe acute respiratory syndrome coronavirus replication

scientific article

Generation of a Single-Cycle Replicable Rift Valley Fever Vaccine

scientific article published on January 2016

Immunogenicity of a recombinant Rift Valley fever MP-12-NSm deletion vaccine candidate in calves.

scientific article published on 27 August 2013

Inhibition of Stress Granule Formation by Middle East Respiratory Syndrome Coronavirus 4a Accessory Protein Facilitates Viral Translation, Leading to Efficient Virus Replication

scholarly article by Keisuke Nakagawa published in October 2018

Interplay between coronavirus, a cytoplasmic RNA virus, and nonsense-mediated mRNA decay pathway

article published in the Proceedings of the National Academy of Sciences of the United States of America

Interplay between the Virus and Host in Rift Valley Fever Pathogenesis

scientific article published on 27 February 2015

Interplay between viruses and host mRNA degradation ⬇️

scientific article published on December 26, 2012

Introduction to Virology special issue featuring nidovirus research

scientific article published on 01 April 2018

Mechanism of tripartite RNA genome packaging in Rift Valley fever virus ⬇️

scientific article published on December 27, 2010

Mechanistic Insight into the Host Transcription Inhibition Function of Rift Valley Fever Virus NSs and Its Importance in Virulence

scientific article

Metagenomic identification and sequence analysis of a Teschovirus A-related virus in porcine feces in Japan, 2014-2016

scientific article published on 11 October 2018

Middle East Respiratory Syndrome Coronavirus nsp1 Inhibits Host Gene Expression by Selectively Targeting mRNAs Transcribed in the Nucleus while Sparing mRNAs of Cytoplasmic Origin

scientific article

Murine coronavirus nonstructural protein p28 arrests cell cycle in G0/G1 phase.

scientific article published on October 2004

Murine coronavirus replication induces cell cycle arrest in G0/G1 phase.

scientific article

Murine coronavirus replication-induced p38 mitogen-activated protein kinase activation promotes interleukin-6 production and virus replication in cultured cells

scientific article

Murine coronavirus-induced apoptosis in 17Cl-1 cells involves a mitochondria-mediated pathway and its downstream caspase-8 activation and bid cleavage

scientific article published on October 2002

NSm and 78-kilodalton proteins of Rift Valley fever virus are nonessential for viral replication in cell culture.

scientific article

NSm protein of Rift Valley fever virus suppresses virus-induced apoptosis

scientific article

Nucleocapsid-independent specific viral RNA packaging via viral envelope protein and viral RNA signal.

scientific article

Protein Phosphatase-1 regulates Rift Valley fever virus replication

scientific article published on 19 January 2016

Rapid Accumulation of Virulent Rift Valley Fever Virus in Mice from an Attenuated Virus Carrying a Single Nucleotide Substitution in the M RNA

scientific article

Rescue of infectious rift valley fever virus entirely from cDNA, analysis of virus lacking the NSs gene, and expression of a foreign gene

scientific article published on March 2006

Rift Valley fever virus

scientific article published on December 2004

Rift Valley fever virus NSs mRNA is transcribed from an incoming anti-viral-sense S RNA segment

scientific article

Rift Valley fever virus NSs protein promotes post-transcriptional downregulation of protein kinase PKR and inhibits eIF2alpha phosphorylation

scientific article published on 6 February 2009

Rift valley fever vaccines

scientific article

Rift valley fever virus L protein forms a biologically active oligomer

scientific article published on 7 October 2009

Rift valley fever virus nonstructural protein NSs promotes viral RNA replication and transcription in a minigenome system

scientific article

Roles of the Coding and Noncoding Regions of Rift Valley Fever Virus RNA Genome Segments in Viral RNA Packaging ⬇️

scientific article published on January 25, 2012

SARS coronavirus accessory proteins.

scientific article

SARS coronavirus nsp1 protein induces template-dependent endonucleolytic cleavage of mRNAs: viral mRNAs are resistant to nsp1-induced RNA cleavage

scientific article

Safety and immunogenicity of recombinant Rift Valley fever MP-12 vaccine candidates in sheep.

scientific article published on 12 November 2012

Severe acute respiratory syndrome and the innate immune responses: modulation of effector cell function without productive infection

scientific article published on June 2005

Severe acute respiratory syndrome coronavirus 3a protein is a viral structural protein

scientific article

Severe acute respiratory syndrome coronavirus 3a protein is released in membranous structures from 3a protein-expressing cells and infected cells

scientific article

Severe acute respiratory syndrome coronavirus 7a accessory protein is a viral structural protein

scientific article

Severe acute respiratory syndrome coronavirus accessory protein 6 is a virion-associated protein and is released from 6 protein-expressing cells

scientific article published on 7 March 2007

Severe acute respiratory syndrome coronavirus infection of mice transgenic for the human Angiotensin-converting enzyme 2 virus receptor

scientific article published on 15 November 2006

Severe acute respiratory syndrome coronavirus nsp1 protein suppresses host gene expression by promoting host mRNA degradation

scholarly article

Severe acute respiratory syndrome coronavirus nsp1 suppresses host gene expression, including that of type I interferon, in infected cells

scientific article

Severe acute respiratory syndrome coronavirus protein nsp1 is a novel eukaryotic translation inhibitor that represses multiple steps of translation initiation

scientific article published on 3 October 2012

Single-cycle replicable Rift Valley fever virus mutants as safe vaccine candidates

scientific article

Suppression of host gene expression by nsp1 proteins of group 2 bat coronaviruses

scientific article published on 04 March 2009

The C-Terminal Region of Rift Valley Fever Virus NSm Protein Targets the Protein to the Mitochondrial Outer Membrane and Exerts Antiapoptotic Function ⬇️

scientific article published on October 24, 2012

The Endonucleolytic RNA Cleavage Function of nsp1 of Middle East Respiratory Syndrome Coronavirus Promotes the Production of Infectious Virus Particles in Specific Human Cell Lines

scholarly article by Keisuke Nakagawa et al published 1 November 2018 in Journal of Virology

The contribution of the cytoplasmic retrieval signal of severe acute respiratory syndrome coronavirus to intracellular accumulation of S proteins and incorporation of S protein into virus-like particles

scientific article published on 4 May 2016

The nucleocapsid protein of Rift Valley fever virus is a potent human CD8+ T cell antigen and elicits memory responses

scientific article

The pathogenesis of Rift Valley fever

scientific article

Two palmitylated cysteine residues of the severe acute respiratory syndrome coronavirus spike (S) protein are critical for S incorporation into virus-like particles, but not for M–S co-localization ⬇️

scientific article published on January 13, 2012

Whole genome analysis of a novel picornavirus related to the Enterovirus/Sapelovirus supergroup from porcine feces in Japan

scientific article published on 15 September 2018

List of works by Shinji Makino

A new comprehensive method for detection of livestock-related pathogenic viruses using a target enrichment system

A novel defective recombinant porcine enterovirus G virus carrying a porcine torovirus papain-like cysteine protease gene and a putative anti-apoptosis gene in place of viral structural protein genes

A single-cycle replicable Rift Valley fever phlebovirus vaccine carrying a mutated NSs confers full protection from lethal challenge in mice

A structural analysis of M protein in coronavirus assembly and morphology

A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein

Alphacoronavirus transmissible gastroenteritis virus nsp1 protein suppresses protein translation in mammalian cells and in cell-free HeLa cell extracts but not in rabbit reticulocyte lysate

Characterization of N protein self-association in coronavirus ribonucleoprotein complexes

Characterization of Rift Valley fever virus transcriptional terminations.

Characterization of synthetic Chikungunya viruses based on the consensus sequence of recent E1-226V isolates

Chimeric coronavirus-like particles carrying severe acute respiratory syndrome coronavirus (SCoV) S protein protect mice against challenge with SCoV

Coronavirus nonstructural protein 1: Common and distinct functions in the regulation of host and viral gene expression

Correction: Rapid Accumulation of Virulent Rift Valley Fever Virus in Mice from an Attenuated Virus Carrying a Single Nucleotide Substitution in the M RNA.

Cyclosporin A inhibits the replication of diverse coronaviruses

Dembo polymerase chain reaction technique for detection of bovine abortion, diarrhea, and respiratory disease complex infectious agents in potential vectors and reservoirs

Development of a novel, single-cycle replicable rift valley Fever vaccine

Differential virological and immunological outcome of severe acute respiratory syndrome coronavirus infection in susceptible and resistant transgenic mice expressing human angiotensin-converting enzyme 2.

Dual functions of Rift Valley fever virus NSs protein: inhibition of host mRNA transcription and post-transcriptional downregulation of protein kinase PKR.

Exogenous ACE2 expression allows refractory cell lines to support severe acute respiratory syndrome coronavirus replication

Generation of a Single-Cycle Replicable Rift Valley Fever Vaccine

Immunogenicity of a recombinant Rift Valley fever MP-12-NSm deletion vaccine candidate in calves.

Inhibition of Stress Granule Formation by Middle East Respiratory Syndrome Coronavirus 4a Accessory Protein Facilitates Viral Translation, Leading to Efficient Virus Replication

Interplay between coronavirus, a cytoplasmic RNA virus, and nonsense-mediated mRNA decay pathway

Interplay between the Virus and Host in Rift Valley Fever Pathogenesis

Interplay between viruses and host mRNA degradation ⬇️

Introduction to Virology special issue featuring nidovirus research

Mechanism of tripartite RNA genome packaging in Rift Valley fever virus ⬇️

Mechanistic Insight into the Host Transcription Inhibition Function of Rift Valley Fever Virus NSs and Its Importance in Virulence

Metagenomic identification and sequence analysis of a Teschovirus A-related virus in porcine feces in Japan, 2014-2016

Middle East Respiratory Syndrome Coronavirus nsp1 Inhibits Host Gene Expression by Selectively Targeting mRNAs Transcribed in the Nucleus while Sparing mRNAs of Cytoplasmic Origin

Murine coronavirus nonstructural protein p28 arrests cell cycle in G0/G1 phase.

Murine coronavirus replication induces cell cycle arrest in G0/G1 phase.

Murine coronavirus replication-induced p38 mitogen-activated protein kinase activation promotes interleukin-6 production and virus replication in cultured cells

Murine coronavirus-induced apoptosis in 17Cl-1 cells involves a mitochondria-mediated pathway and its downstream caspase-8 activation and bid cleavage

NSm and 78-kilodalton proteins of Rift Valley fever virus are nonessential for viral replication in cell culture.

NSm protein of Rift Valley fever virus suppresses virus-induced apoptosis

Nucleocapsid-independent specific viral RNA packaging via viral envelope protein and viral RNA signal.

Protein Phosphatase-1 regulates Rift Valley fever virus replication

Rapid Accumulation of Virulent Rift Valley Fever Virus in Mice from an Attenuated Virus Carrying a Single Nucleotide Substitution in the M RNA

Rescue of infectious rift valley fever virus entirely from cDNA, analysis of virus lacking the NSs gene, and expression of a foreign gene

Rift Valley fever virus

Rift Valley fever virus NSs mRNA is transcribed from an incoming anti-viral-sense S RNA segment

Rift Valley fever virus NSs protein promotes post-transcriptional downregulation of protein kinase PKR and inhibits eIF2alpha phosphorylation

Rift valley fever vaccines

Rift valley fever virus L protein forms a biologically active oligomer

Rift valley fever virus nonstructural protein NSs promotes viral RNA replication and transcription in a minigenome system

Roles of the Coding and Noncoding Regions of Rift Valley Fever Virus RNA Genome Segments in Viral RNA Packaging ⬇️

SARS coronavirus accessory proteins.

SARS coronavirus nsp1 protein induces template-dependent endonucleolytic cleavage of mRNAs: viral mRNAs are resistant to nsp1-induced RNA cleavage

Safety and immunogenicity of recombinant Rift Valley fever MP-12 vaccine candidates in sheep.

Severe acute respiratory syndrome and the innate immune responses: modulation of effector cell function without productive infection

Severe acute respiratory syndrome coronavirus 3a protein is a viral structural protein

Severe acute respiratory syndrome coronavirus 3a protein is released in membranous structures from 3a protein-expressing cells and infected cells

Severe acute respiratory syndrome coronavirus 7a accessory protein is a viral structural protein

Severe acute respiratory syndrome coronavirus accessory protein 6 is a virion-associated protein and is released from 6 protein-expressing cells

Severe acute respiratory syndrome coronavirus infection of mice transgenic for the human Angiotensin-converting enzyme 2 virus receptor

Severe acute respiratory syndrome coronavirus nsp1 protein suppresses host gene expression by promoting host mRNA degradation

Severe acute respiratory syndrome coronavirus nsp1 suppresses host gene expression, including that of type I interferon, in infected cells

Severe acute respiratory syndrome coronavirus protein nsp1 is a novel eukaryotic translation inhibitor that represses multiple steps of translation initiation

Single-cycle replicable Rift Valley fever virus mutants as safe vaccine candidates

Suppression of host gene expression by nsp1 proteins of group 2 bat coronaviruses

The C-Terminal Region of Rift Valley Fever Virus NSm Protein Targets the Protein to the Mitochondrial Outer Membrane and Exerts Antiapoptotic Function ⬇️

The Endonucleolytic RNA Cleavage Function of nsp1 of Middle East Respiratory Syndrome Coronavirus Promotes the Production of Infectious Virus Particles in Specific Human Cell Lines

The contribution of the cytoplasmic retrieval signal of severe acute respiratory syndrome coronavirus to intracellular accumulation of S proteins and incorporation of S protein into virus-like particles

The nucleocapsid protein of Rift Valley fever virus is a potent human CD8+ T cell antigen and elicits memory responses

The pathogenesis of Rift Valley fever

Two palmitylated cysteine residues of the severe acute respiratory syndrome coronavirus spike (S) protein are critical for S incorporation into virus-like particles, but not for M–S co-localization ⬇️

Whole genome analysis of a novel picornavirus related to the Enterovirus/Sapelovirus supergroup from porcine feces in Japan