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List of works by Hans-Peter Kiem

(211)Astatine-Conjugated Monoclonal CD45 Antibody-Based Nonmyeloablative Conditioning for Stem Cell Gene Therapy

scientific article published on June 2015

A Combined In Vivo HSC Transduction/Selection Approach Results in Efficient and Stable Gene Expression in Peripheral Blood Cells in Mice

scientific article published on 10 November 2017

A Cure for HIV Infection: "Not in My Lifetime" or "Just Around the Corner"?

scientific article

A Nonhuman Primate Transplantation Model to Evaluate Hematopoietic Stem Cell Gene Editing Strategies for β-Hemoglobinopathies

scientific article published on 21 November 2017

A capsid-modified, conditionally replicating oncolytic adenovirus vector expressing TRAIL Leads to enhanced cancer cell killing in human glioblastoma models

scientific article

A curative regimen would decrease HIV prevalence but not HIV incidence unless targeted to an ART-naïve population

scientific article published on 24 February 2016

A distinct hematopoietic stem cell population for rapid multilineage engraftment in nonhuman primates.

scientific article published in November 2017

A phase I/II study of mycophenolate mofetil in combination with cyclosporine for prophylaxis of acute graft-versus-host disease after myeloablative conditioning and allogeneic hematopoietic cell transplantation

scientific article published in July 2005

A retrospective comparison of tacrolimus versus cyclosporine with methotrexate for immunosuppression after allogeneic hematopoietic cell transplantation with mobilized blood cells

scientific article

A retroviral vector common integration site between leupaxin and zinc finger protein 91 (ZFP91) observed in baboon hematopoietic repopulating cells

scientific article published on 29 April 2010

AMD3100 re-dosing fails to repeatedly mobilize hematopoietic stem cells in the non-human primate and humanized mouse

scientific article published on 01 December 2020

ASSESSMENT, AND STREAMLINED PREPARATION OF LOW CYTOTOXICITY LENTIVIRAL VECTORS FOR MOBILIZED HUMAN HEMATOPOIETIC STEM CELL TRANSDUCTION

scientific article published on 27 May 2020

Abrogated cryptic activation of lentiviral transfer vectors ⬇️

scientific article published on January 1, 2012

Allogeneic hematopoietic stem cell transplantation for myelofibrosis

scientific article published on 14 August 2003

American Society of Gene Therapy (ASGT) ad hoc subcommittee on retroviral-mediated gene transfer to hematopoietic stem cells

scientific article

Autologous Stem Cell Transplantation Disrupts Adaptive Immune Responses during Rebound Simian/Human Immunodeficiency Virus Viremia

scientific article published on 12 April 2017

Autologous, Gene-Modified Hematopoietic Stem and Progenitor Cells Repopulate the Central Nervous System with Distinct Clonal Variants

scientific article published on 9 July 2019

Blockade of alpha6-integrin reveals diversity in homing patterns among human, baboon, and murine cells

scientific article

C peptides as entry inhibitors for gene therapy

scientific article

CAR T-cell therapy for cancer and HIV through novel approaches to HIV-associated haematological malignancies

scientific article published on 04 August 2020

CCR5-edited gene therapies for HIV cure: Closing the door to viral entry

scientific article

CD34(+) expansion with Delta-1 and HOXB4 promotes rapid engraftment and transfusion independence in a Macaca nemestrina cord blood transplant model

scientific article published on 16 April 2013

CRISPR/Cas9 for the treatment of haematological diseases: a journey from bacteria to the bedside

scientific article published on 07 June 2020

Call for Papers: Expanding the Scale and Scope of Therapeutic Gene Editing

scientific article published on 16 July 2020

Canine models of gene-modified hematopoiesis

scientific article

Cell and Gene Therapy for HIV Cure

scientific article published on 19 December 2017

Cell-Delivered Entry Inhibitors for HIV-1: CCR5 Downregulation and Blocking Virus/Membrane Fusion in Defending the Host Cell Population

scientific article

Challenges in vector and trial design using retroviral vectors for long-term gene correction in hematopoietic stem cell gene therapy

scientific article published in June 2012

Charting a clear path: the ASGCT Standardized Pathways Conference

scientific article

Chemoprotection in glioblastoma therapy: reality or a dream?

scientific article published in September 2012

Chimeric antigen receptor T-cell approaches to HIV cure

article

Clonal kinetics and single-cell transcriptional profiling of CAR-T cells in patients undergoing CD19 CAR-T immunotherapy

scientific article published on 10 January 2020

Cocal-pseudotyped lentiviral vectors resist inactivation by human serum and efficiently transduce primate hematopoietic repopulating cells

scientific article

Combination of HOXB4 and Delta-1 ligand improves expansion of cord blood cells ⬇️

scientific article published on October 4, 2010

Comparative analysis of risk factors for acute graft-versus-host disease and for chronic graft-versus-host disease according to National Institutes of Health consensus criteria

scientific article

Comparison of HIV-derived lentiviral and MLV-based gammaretroviral vector integration sites in primate repopulating cells

scientific article published on 17 April 2007

Comparison of mesenchymal stem cells from different tissues to suppress T-cell activation

scientific article published on 01 January 2007

Complications of a temozolomide overdose: a case report

scientific article

Concurrent blockade of alpha4-integrin and CXCR4 in hematopoietic stem/progenitor cell mobilization

scientific article

Conditioning with targeted busulfan and cyclophosphamide for hemopoietic stem cell transplantation from related and unrelated donors in patients with myelodysplastic syndrome

scientific article published in August 2002

Continuous electrical oscillations emerge from a coupled network: a study of the inferior olive using lentiviral knockdown of connexin36.

scientific article

Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal

scientific article

Correction: Long-term persistence and function of hematopoietic stem cell-derived chimeric antigen receptor T cells in a nonhuman primate model of HIV/AIDS.

scientific article

Correction: Stem Cell Selection In Vivo Using Foamy Vectors Cures Canine Pyruvate Kinase Deficiency.

scientific article published on 30 October 2013

Corrigendum to "Long-term Regulation of Genetically Modified Primary Hematopoietic Cells in Dogs".

scientific article published on November 2011

Corrigendum: Suppression of luteinizing hormone enhances HSC recovery after hematopoietic injury

scientific article published on 01 April 2018

Coupling endonucleases with DNA end–processing enzymes to drive gene disruption ⬇️

scientific article published on September 2, 2012

Current translational and clinical practices in hematopoietic cell and gene therapy ⬇️

scientific article published on August 1, 2012

Cyclophosphamide promotes engraftment of gene-modified cells in a mouse model of Fanconi anemia without causing cytogenetic abnormalities

scientific article published on 3 June 2012

DNA Barcoding in Nonhuman Primates Reveals Important Limitations in Retrovirus Integration Site Analysis

scientific article published on 30 March 2020

De novo generation of CD4 T cells against viruses present in the host during immune reconstitution

scientific article published on 15 March 2005

Development of Third-generation Cocal Envelope Producer Cell Lines for Robust Lentiviral Gene Transfer into Hematopoietic Stem Cells and T-cells

scientific article published on 8 April 2016

Devouring the Hematopoietic Stem Cell: Setting the Table for Marrow Cell Transplantation

scientific article published on November 2016

Differences in F36VMpl-based in vivo selection among large animal models

scientific article published on October 2004

Differential effects of HOXB4 and NUP98-HOXA10hd on hematopoietic repopulating cells in a nonhuman primate model.

scientific article published on 6 September 2011

Differential effects of HOXB4 on nonhuman primate short- and long-term repopulating cells

scientific article (publication date: May 2006)

Differential effects of bexarotene on intrinsic and extrinsic pathways in TRAIL-induced apoptosis in two myeloid leukemia cell lines

scientific article published on May 2007

Differential impact of transplantation on peripheral and tissue-associated viral reservoirs: Implications for HIV gene therapy.

scientific article published on 19 April 2018

Differential responses of FLIPLong and FLIPShort-overexpressing human myeloid leukemia cells to TNF-alpha and TRAIL-initiated apoptotic signals

scientific article published on 05 October 2008

Direct comparison of steady-state marrow, primed marrow, and mobilized peripheral blood for transduction of hematopoietic stem cells in dogs

scientific article published in November 2003

Distinct hematopoietic stem/progenitor cell populations are responsible for repopulating NOD/SCID mice compared with nonhuman primates

scientific article published on 19 June 2003

Duration of immunosuppressive treatment for chronic graft-versus-host disease

scientific article published on 3 August 2004

Ectopic expression of HOXC6 blocks myeloid differentiation and predisposes to malignant transformation

scientific article

Effective Multi-lineage Engraftment in a Mouse Model of Fanconi Anemia Using Non-genotoxic Antibody-Based Conditioning

scientific article published on 08 February 2020

Effects of HOXB4 overexpression on ex vivo expansion and immortalization of hematopoietic cells from different species

scientific article published on 17 May 2007

Efficient Enrichment of Gene-Modified Primary T Cells via CCR5-Targeted Integration of Mutant Dihydrofolate Reductase

article

Efficient Modification of the CCR5 Locus in Primary Human T Cells With megaTAL Nuclease Establishes HIV-1 Resistance

scientific article published on 23 August 2016

Efficient and stable MGMT-mediated selection of long-term repopulating stem cells in nonhuman primates. ⬇️

scientific article

Efficient characterization of retro-, lenti-, and foamyvector-transduced cell populations by high-accuracy insertion site sequencing.

scientific article published in May 2003

Efficient gene transfer to hematopoietic repopulating cells using concentrated RD114-pseudotype vectors produced by human packaging cells

scientific article published on February 2004

Efficient generation of antigen-specific cytotoxic T cells using retrovirally transduced CD40-activated B cells

scientific article published on 01 August 2002

Efficient generation of nonhuman primate induced pluripotent stem cells

scientific article

Efficient generation, purification, and expansion of CD34(+) hematopoietic progenitor cells from nonhuman primate-induced pluripotent stem cells

scientific article

Efficient lentiviral gene transfer to canine repopulating cells using an overnight transduction protocol

scientific article published on 22 January 2004

Efficient marking of murine long-term repopulating stem cells targeting unseparated marrow cells at low lentiviral vector particle concentration

scientific article published in June 2004

Efficient transduction and engraftment of G-CSF-mobilized peripheral blood CD34+ cells in nonhuman primates using GALV-pseudotyped gammaretroviral vectors

scientific article published on 21 April 2006

Efficient transduction of pigtailed macaque hematopoietic repopulating cells with HIV-based lentiviral vectors

scientific article published on 3 April 2008

Endothelial Cells Promote Expansion of Long-Term Engrafting Marrow Hematopoietic Stem and Progenitor Cells in Primates

scientific article

Engineering resistance to CD33-targeted immunotherapy in normal hematopoiesis by CRISPR/Cas9-deletion of CD33 exon 2

scientific article published on 05 October 2018

Envelope-Specific Adaptive Immunity following Transplantation of Hematopoietic Stem Cells Modified with VSV-G Lentivirus

scientific article published on 10 October 2020

Evaluation of NIH consensus criteria for classification of late acute and chronic GVHD.

scientific article published on 21 May 2009

Evaluation of biodistribution and safety of adenovirus vectors containing group B fibers after intravenous injection into baboons.

scientific article

Evaluation of posttransplant methotrexate to facilitate engraftment in the canine major histocompatibility complex-haploidentical nonmyeloablative transplant model

scientific article published on July 2010

Evidence for persistence of the SHIV reservoir early after MHC haploidentical hematopoietic stem cell transplantation

scientific article published in Nature Communications

Ex vivo expansion and lentiviral transduction of Macaca nemestrina CD4+ T cells

scientific article

Ex vivo selection for oncoretrovirally transduced green fluorescent protein-expressing CD34-enriched cells increases short-term engraftment of transduced cells in baboons

scientific article

Expansion of SCID repopulating cells does not prove expansion of hematopoietic stem cells

scientific article published on 01 July 2006

Extended core sequences from the cHS4 insulator are necessary for protecting retroviral vectors from silencing position effects

scientific article published on April 2007

Extended survival of glioblastoma patients after chemoprotective HSC gene therapy

scientific article published on May 2012

Factors associated with durable EFS in adult B-cell ALL patients achieving MRD-negative CR after CD19 CAR T-cell therapy

scientific article published on 06 February 2019

Factors associated with outcomes after a second CD19-targeted CAR T-cell infusion for refractory B cell malignancies

scientific article published on 23 September 2020

Fanconi anemia type C-deficient hematopoietic cells are resistant to TRAIL (TNF-related apoptosis-inducing ligand)-induced cleavage of pro-caspase-8.

scientific article published on September 2004

Foamy and lentiviral vectors transduce canine long-term repopulating cells at similar efficiency

scientific article

Foamy virus vector integration sites in normal human cells

scholarly article

Foamy-virus-mediated gene transfer to canine repopulating cells

scientific article published on 12 September 2006

Fundamental role of inferior olive connexin 36 in muscle coherence during tremor.

scientific article

Gene therapy enhances chemotherapy tolerance and efficacy in glioblastoma patients

scientific article

Gene therapy for Fanconi anemia: one step closer to the clinic.

scientific article published on February 2012

Gene therapy in the transplantation of allogeneic organs and stem cells

scientific article published on December 2007

Gene therapy studies in a canine model of X-linked severe combined immunodeficiency

scientific article

Gene transfer in AAV seropositive rhesus macaques following rapamycin treatment and subcutaneous delivery of AAV6 but not retargeted AAV6 vectors

scientific article published on 30 September 2020

Genetic modification of hematopoietic stem cells as a therapy for HIV/AIDS.

scientific article

Genetically modified hematopoietic stem cell transplantation for HIV-1-infected patients: can we achieve a cure?

scientific article

HIV eradication--from Berlin to Boston

scientific article

HIV infection results in clonal expansions containing integrations within pathogenesis-related biological pathways

scientific article published on 12 July 2018

HLA-Haploidentical Hematopoietic Cell Transplantation for Treatment of Non-Malignant Diseases Using Nonmyeloablative Conditioning and Post-Transplant Cyclophosphamide

scientific article published on 28 March 2020

HLA-matched related donor hematopoietic cell transplantation in 43 patients with Fanconi anemia conditioned with 60 mg/kg of cyclophosphamide

scientific article

Haploidentical Bone Marrow Transplantation with Post-Transplant Cyclophosphamide for Children and Adolescents with Fanconi Anemia

scientific article published on 7 November 2016

Hematopoietic Stem Cell Approaches to Cancer

scientific article published in October 2017

Hematopoietic stem cell engraftment: a direct comparison between intramarrow and intravenous injection in nonhuman primates

scientific article published in July 2007

Hematopoietic stem cell expansion and gene therapy

scientific article

Hematopoietic stem cell expansion facilitates multilineage engraftment in a nonhuman primate cord blood transplantation model.

scientific article

Hematopoietic stem cell transduction and amplification in large animal models

scientific article published in December 2005

Hematopoietic stem-cell behavior in nonhuman primates

scientific article

Hematopoietic-stem-cell-based gene therapy for HIV disease

scientific article

Hepatic cells derived from induced pluripotent stem cells of pigtail macaques support hepatitis C virus infection

scientific article published on 25 July 2013

High incidence of leukemia in large animals after stem cell gene therapy with a HOXB4-expressing retroviral vector

scientific article

High-throughput genomic mapping of vector integration sites in gene therapy studies

scientific article published on January 2014

Highly efficient gene transfer into baboon marrow repopulating cells using GALV-pseudotype oncoretroviral vectors produced by human packaging cells

scientific article published on 8 August 2002

Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts.

scientific article

Human hematopoietic stem cell maintenance and myeloid cell development in next-generation humanized mouse models

article

Immuno-therapy with anti-CTLA4 antibodies in tolerized and non-tolerized mouse tumor models.

scientific article

Improved short-term engraftment of lentivirally versus gammaretrovirally transduced allogeneic canine repopulating cells

scientific article published on 01 May 2007

In vivo administration of interferon gamma does not cause marrow aplasia in mice with a targeted disruption of FANCC

scientific article published on 01 November 2002

In vivo base editing by a single intravenous vector injection for treatment of hemoglobinopathies

scientific article published in 2022

In vivo gene therapy for canine SCID-X1 using cocal-pseudotyped lentiviral vector

scientific article published on 01 August 2020

In vivo protection of activated Tyr22-dihydrofolate reductase gene-modified canine T lymphocytes from methotrexate.

scientific article published on June 2013

In vivo selection and chemoprotection after drug resistance gene therapy in a nonmyeloablative allogeneic transplantation setting in dogs

scientific article published in May 2007

In vivo transduction of primitive mobilized hematopoietic stem cells after intravenous injection of integrating adenovirus vectors

scientific article published on 23 August 2016

In-Vivo Gene Therapy with Foamy Virus Vectors

scientific article published on 23 November 2019

Induction of cytotoxic T-lymphocyte responses to enhanced green and yellow fluorescent proteins after myeloablative conditioning ⬇️

scientific article published on September 25, 2003

Induction of transgene-specific cytotoxic T lymphocyte responses after transplantation of gene-modified CD34+ cells despite nonablative immunosuppressive conditioning

scientific article

Insights into leukemia-initiating cell frequency and self-renewal from a novel canine model of leukemia.

scientific article published on 8 October 2010

Interleukin-7 improves CD4 T-cell reconstitution after autologous CD34 cell transplantation in monkeys

scientific article

Interleukin-7 improves reconstitution of antiviral CD4 T cells

scientific article

International AIDS Society global scientific strategy: towards an HIV cure 2016.

scientific article published on 11 July 2016

Intravenous injection of a foamy virus vector to correct canine SCID-X1.

scientific article

In Vivo Hematopoietic Stem Cell Transduction.

scientific article published on October 2017

In Vivo Murine-Matured Human CD3+ Cells as a Preclinical Model for T Cell-Based Immunotherapies.

scientific article

Isolation of a Highly Purified HSC-enriched CD34+CD90+CD45RA- Cell Subset for Allogeneic Transplantation in the Nonhuman Primate Large-animal Model

scientific article published on 15 July 2020

Kinetics of fluorescence expression in nonhuman primates transplanted with GFP retrovirus-modified CD34 cells

scientific article published on 01 July 2002

Lack of viral control and development of combination antiretroviral therapy escape mutations in macaques after bone marrow transplantation

scientific article

Large animal models for foamy virus vector gene therapy

scientific article

Lentivirus-mediated Gene Transfer in Hematopoietic Stem Cells Is Impaired in SHIV-infected, ART-treated Nonhuman Primates

scientific article

Lessons Learned from Two Decades of Clinical Trial Experience in Gene Therapy for Fanconi Anemia

scientific article published on 19 January 2017

Lessons from London and Berlin: Designing A Scalable Gene Therapy Approach for HIV Cure

scientific article published on 01 May 2019

Long-Term Persistence of Anti-HIV Broadly Neutralizing Antibody-Secreting Hematopoietic Cells in Humanized Mice

article

Long-term clinical and molecular follow-up of large animals receiving retrovirally transduced stem and progenitor cells: no progression to clonal hematopoiesis or leukemia

scientific article published in March 2004

Long-term multilineage engraftment of autologous genome-edited hematopoietic stem cells in nonhuman primates

scientific article published on 15 March 2016

Long-term persistence and function of hematopoietic stem cell-derived chimeric antigen receptor T cells in a nonhuman primate model of HIV/AIDS.

scientific article published on 28 December 2017

Long-term polyclonal and multilineage engraftment of methylguanine methyltransferase P140K gene-modified dog hematopoietic cells in primary and secondary recipients

scientific article published on 31 March 2009

Long-term regulation of genetically modified primary hematopoietic cells in dogs

scientific article

Longitudinal assessment of morbidity and acute graft-versus-host disease after allogeneic hematopoietic cell transplantation: retrospective analysis of a multicenter phase III study

scientific article published on June 2009

Loss of immune homeostasis dictates SHIV rebound after stem-cell transplantation

scientific article published on 23 February 2017

MISTRG mice support engraftment and assessment of nonhuman primate hematopoietic stem and progenitor cells

scientific article published on 25 December 2018

Marrow grafts from HLA-identical siblings for severe aplastic anemia: does limiting the number of transplanted marrow cells reduce the risk of chronic GvHD?

scientific article published on August 2016

Methylguanine methyltransferase-mediated in vivo selection and chemoprotection of allogeneic stem cells in a large-animal model

scientific article published on November 2003

Minimal conditioning in Fanconi anemia promotes multi-lineage marrow engraftment at 10-fold lower cell doses

scientific article published on 01 October 2018

Modeling promising nonmyeloablative conditioning regimens in nonhuman primates

scientific article

Morbidity and mortality of chronic GVHD after hematopoietic stem cell transplantation from HLA-identical siblings for patients with aplastic or refractory anemias

scientific article published in January 2002

Mouse models in hematopoietic stem cell gene therapy and genome editing

scientific article published on 06 November 2019

Multilineage polyclonal engraftment of Cal-1 gene-modified cells and in vivo selection after SHIV infection in a nonhuman primate model of AIDS

scientific article published on 24 February 2016

Nanoparticle Biokinetics in Mice and Nonhuman Primates

scientific article

Next-Generation Conditioning for Bone Marrow Transplantation: Paving the Way for CAR-T Cell-Based Conditioning

scientific article published on 01 May 2018

No evidence of clonal dominance after transplant of HOXB4-expanded cord blood cells in a nonhuman primate model

scientific article

Novel lineage depletion preserves autologous blood stem cells for gene therapy of Fanconi anemia complementation group A

article

Novel reporter systems for facile evaluation of I-SceI-mediated genome editing

scientific article published on 21 November 2011

Outcome of allogeneic hematopoietic cell transplantation from HLA-identical siblings for severe aplastic anemia in patients over 40 years of age.

scientific article

Outside the box--novel therapeutic strategies for glioblastoma

scientific article published on January 2012

Overexpression of glutathione-S-transferase, MGSTII, confers resistance to busulfan and melphalan

scientific article

Pharmacologically regulated in vivo selection in a large animal

scientific article published in September 2002

Pigtailed macaques as a model to study long-term safety of lentivirus vector-mediated gene therapy for hemoglobinopathies

scientific article published on 17 December 2014

Polyclonal chemoprotection against temozolomide in a large-animal model of drug resistance gene therapy

scientific article published on 19 October 2004

Polyclonal long-term repopulating stem cell clones in a primate model

scientific article published in October 2002

Positive selection of mC46-expressing CD4+ T cells and maintenance of virus specific immunity in a primate AIDS model.

scientific article published on 29 May 2013

Preparation and Gene Modification of Nonhuman Primate Hematopoietic Stem and Progenitor Cells

scientific article published on 15 February 2019

Proliferation-linked apoptosis of adoptively transferred T cells after IL-15 administration in macaques

scientific article

Protection of stem cell-derived lymphocytes in a primate AIDS gene therapy model after in vivo selection

scientific article

Psoralen and ultraviolet A irradiation (PUVA) as therapy for steroid-resistant cutaneous acute graft-versus-host disease

scientific article

Purification of Human CD34+CD90+ HSCs Reduces Target Cell Population and Improves Lentiviral Transduction for Gene Therapy

scientific article published on 15 July 2020

Radiation-induced glioblastoma multiforme in two adult baboons (Papio cynocephalus anubis).

scientific article published in June 2004

Rapamycin relieves lentiviral vector transduction resistance in human and mouse hematopoietic stem cells

scientific article

Rapid immune reconstitution of SCID-X1 canines after G-CSF/AMD3100 mobilization and in vivo gene therapy

article

Reduced incidence of acute and chronic graft-versus-host disease with the addition of thymoglobulin to a targeted busulfan/cyclophosphamide regimen.

scientific article

Reduced toxicity and prompt engraftment after minimal conditioning of a patient with Fanconi anemia undergoing hematopoietic stem cell transplantation from an HLA-matched unrelated donor

scientific article published on 01 July 2003

Refining Current Scientific Priorities and Identifying New Scientific Gaps in HIV-Related Heart, Lung, Blood, and Sleep Research

scientific article published on 20 May 2017

Resveratrol trimer enhances gene delivery to hematopoietic stem cells by reducing antiviral restriction at endosomes

scientific article published on 01 October 2019

Rethinking the Regulatory Infrastructure for Human Gene Transfer Clinical Trials

scientific article published on August 2016

Robust Expansion of HIV CAR T Cells Following Antigen Boosting in ART-Suppressed Nonhuman Primates

scientific article published on 02 July 2020

Robust suppression of env-SHIV viremia in Macaca nemestrina by 3-drug ART is independent of timing of initiation during chronic infection

scientific article published on October 2013

SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues

scientific article published on 27 April 2020

Safe and Effective Gene Therapy for Murine Wiskott-Aldrich Syndrome Using an Insulated Lentiviral Vector

scientific article published on 18 December 2016

Safeguarding nonhuman primate iPS cells with suicide genes.

scientific article

Safety and Efficacy of Combination Antiretroviral Therapy in Human Immunodeficiency Virus-Infected Adults Undergoing Autologous or Allogeneic Hematopoietic Cell Transplantation for Hematologic Malignancies

scientific article published on 8 August 2015

Scaffold attachment region-containing retrovirus vectors improve long-term proviral expression after transplantation of GFP-modified CD34+ baboon repopulating cells

scientific article published on 17 July 2003

Screening Clinical Cell Products for Replication Competent Retrovirus: The National Gene Vector Biorepository Experience

article

Semi-automated closed system manufacturing of lentivirus gene-modified haematopoietic stem cells for gene therapy

scientific article published on 20 October 2016

Simian varicella virus in pigtailed macaques (Macaca nemestrina): clinical, pathologic, and virologic features

scientific article published on October 2009

Sirolimus in combination with cyclosporine or tacrolimus plus methotrexate for prevention of graft-versus-host disease following hematopoietic cell transplantation from unrelated donors

scientific article published on May 2008

Sorting Out the Best: Enriching Hematopoietic Stem Cells for Gene Therapy and Editing

article

Stable marking and transgene expression without progression to monoclonality in canine long-term hematopoietic repopulating cells transduced with lentiviral vectors

scientific article published on April 2010

Stem Cell Selection In Vivo Using Foamy Vectors Cures Canine Pyruvate Kinase Deficiency ⬇️

scientific article published on September 13, 2012

Stem cell gene therapy for fanconi anemia: report from the 1st international Fanconi anemia gene therapy working group meeting.

scientific article

Stem cell gene transfer--efficacy and safety in large animal studies.

scientific article

Suppression of luteinizing hormone enhances HSC recovery after hematopoietic injury.

scientific article

Survival of the fittest: in vivo selection and stem cell gene therapy

scientific article

T-cell immunotherapy: looking forward

scientific article published on September 2014

TALEN-Mediated Gene Editing of in Human Hematopoietic Stem Cells Leads to Therapeutic Fetal Hemoglobin Induction

article

TRAILshort Protects against CD4 T Cell Death during Acute HIV Infection

scientific article published on 12 June 2019

Targeted gene disruption to cure HIV

scientific article

Targeted homology-directed repair in blood stem and progenitor cells with CRISPR nanoformulations

scientific article published on 27 May 2019

Targeting the membrane-proximal C2-set domain of CD33 for improved CD33-directed immunotherapy

scientific article published in 2021

The CD33 splice isoform lacking exon 2 as therapeutic target in human acute myeloid leukemia

scientific article published on 18 February 2020

The effect of imatinib on cytomegalovirus reactivation in hematopoietic cell transplantation

scientific article published on December 2009

The evolution of viral integration site analysis

scientific article published on 01 April 2020

The frequency of multipotent CD133(+)CD45RA(-)CD34(+) hematopoietic stem cells is not increased in fetal liver compared with adult stem cell sources

scientific article

The majority of CD4+ T-cell depletion during acute simian-human immunodeficiency virus SHIV89.6P infection occurs in uninfected cells

scientific article published on 03 January 2014

The response to lymphodepletion impacts PFS in patients with aggressive non-Hodgkin lymphoma treated with CD19 CAR T cells

scientific article published on 19 February 2019

Therapeutically relevant engraftment of a CRISPR-Cas9-edited HSC-enriched population with HbF reactivation in nonhuman primates

scientific article published on 01 July 2019

Tightly regulated gene expression in human hematopoietic stem cells after transduction with helper-dependent Ad5/35 vectors

scientific article

Toward a stem cell gene therapy for breast cancer

scientific article published on 27 March 2009

Transgene expression by a large fraction of dendritic cells following autologous transplantation of retrovirally transduced CD34 cells

scientific article published on 01 October 2006

Transmission and expansion of HOXB4-induced leukemia in two immunosuppressed dogs: implications for a new canine leukemia model

scientific article published on 17 July 2009

Transmission of Chagas disease via blood transfusions in 2 immunosuppressed pigtailed macaques (Macaca nemestrina)

scientific article published on February 2014

Treatment change as a predictor of outcome among patients with classic chronic graft-versus-host disease.

scientific article

Unique integration profiles in a canine model of long-term repopulating cells transduced with gammaretrovirus, lentivirus, or foamy virus

scientific article

VISA--Vector Integration Site Analysis server: a web-based server to rapidly identify retroviral integration sites from next-generation sequencing

scientific article published on 7 July 2015

Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells

scientific article

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