List of works - Lydia A Afman

A 12-wk whole-grain wheat intervention protects against hepatic fat: the Graandioos study, a randomized trial in overweight subjects

scientific article published on 01 December 2018

A high-fat SFA, MUFA, or n3 PUFA challenge affects the vascular response and initiates an activated state of cellular adherence in lean and obese middle-aged men.

scientific article published on 24 April 2013

A risk assessment-driven quantitative comparison of gene expression profiles in PBMCs and white adipose tissue of humans and rats after isoflavone supplementation

scientific article published on 13 July 2016

A saturated fatty acid-rich diet induces an obesity-linked proinflammatory gene expression profile in adipose tissue of subjects at risk of metabolic syndrome

scientific article

A scheme for a flexible classification of dietary and health biomarkers

scientific article published on 12 December 2017

A short-term intervention with selenium affects expression of genes implicated in the epithelial-to-mesenchymal transition in the prostate

scientific article published on 6 January 2017

Activation of peroxisome proliferator-activated receptor alpha in human peripheral blood mononuclear cells reveals an individual gene expression profile response

scientific article

Apolipoprotein E genotype status affects habitual human blood mononuclear cell gene expression and its response to fish oil intervention.

scientific article published on 23 March 2016

Changes in gene expression in PBMCs profiles of PPARα target genes in obese and non-obese individuals during fasting.

scientific article published on 4 December 2014

Consumption of a high monounsaturated fat diet reduces oxidative phosphorylation gene expression in peripheral blood mononuclear cells of abdominally overweight men and women.

scientific article

Dairy proteins, dairy lipids, and postprandial lipemia in persons with abdominal obesity (DairyHealth): a 12-wk, randomized, parallel-controlled, double-blinded, diet intervention study

scientific article published on 14 January 2015

Dark chocolate consumption improves leukocyte adhesion factors and vascular function in overweight men.

scientific article published on 03 December 2013

Effect of energy restriction and physical exercise intervention on phenotypic flexibility as examined by transcriptomics analyses of mRNA from adipose tissue and whole body magnetic resonance imaging.

scientific article

Estrogen receptor-mediated effects of isoflavone supplementation were not observed in whole-genome gene expression profiles of peripheral blood mononuclear cells in postmenopausal, equol-producing women.

scientific article published on 24 April 2013

Fasting induces changes in peripheral blood mononuclear cell gene expression profiles related to increases in fatty acid beta-oxidation: functional role of peroxisome proliferator activated receptor alpha in human peripheral blood mononuclear cells

scientific article published in November 2007

Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells.

scientific article

Gene-gene interaction between the cystathionine beta-synthase 31 base pair variable number of tandem repeats and the methylenetetrahydrofolate reductase 677C > T polymorphism on homocysteine levels and risk for neural tube defects

scientific article published in March 2003

Genetic variants of FADS gene cluster, plasma LC-PUFA levels and the association with cognitive function of under-two-year-old Sasaknese Indonesian children

scientific article published on January 2015

Genetic variation in genes of folate metabolism and neural-tube defect risk

scientific article

Guidelines for Biomarker of Food Intake Reviews (BFIRev): how to conduct an extensive literature search for biomarker of food intake discovery.

scientific article published on 20 February 2018

High fat challenges with different fatty acids affect distinct atherogenic gene expression pathways in immune cells from lean and obese subjects.

scientific article published on 26 May 2015

Human nutrigenomics of gene regulation by dietary fatty acids.

scientific article published on 02 December 2011

Increasing protein intake modulates lipid metabolism in healthy young men and women consuming a high-fat hypercaloric diet

scientific article published on 04 June 2014

Inhibition of transmethylation disturbs neurulation in chick embryos

scientific article published in August 2005

Integrated Analys of High-Fat Challenge-Induced Changes in Blood Cell Whole-Genome Gene Expression

scientific article published on 30 September 2019

Isoflavone supplement composition and equol producer status affect gene expression in adipose tissue: a double-blind, randomized, placebo-controlled crossover trial in postmenopausal women.

scientific article

Morphogenetic movements during cranial neural tube closure in the chick embryo and the effect of homocysteine.

scientific article published in September 2005

Nutrigenomics: from molecular nutrition to prevention of disease.

scientific article

Nutritional aspects of metabolic inflammation in relation to health--insights from transcriptomic biomarkers in PBMC of fatty acids and polyphenols

scientific article published on 21 January 2014

PUFAs acutely affect triacylglycerol-derived skeletal muscle fatty acid uptake and increase postprandial insulin sensitivity

scientific article published on 15 February 2012

Phenotyping the effect of diet on non-alcoholic fatty liver disease.

scientific article published on 11 July 2012

Plasma protein profiling reveals protein clusters related to BMI and insulin levels in middle-aged overweight subjects

scientific article

Polymorphisms in the transcobalamin gene: association with plasma homocysteine in healthy individuals and vascular disease patients.

scientific article published in September 2002

Postprandial dietary lipid-specific effects on human peripheral blood mononuclear cell gene expression profiles.

scientific article

Postprandial fatty acid specific changes in circulating oxylipins in lean and obese men after high-fat challenge tests.

scientific article published on 14 October 2013

Pure flavonoid epicatechin and whole genome gene expression profiles in circulating immune cells in adults with elevated blood pressure: A randomised double-blind, placebo-controlled, crossover trial.

scientific article published on 19 April 2018

Quercetin, but Not Epicatechin, Decreases Plasma Concentrations of Methylglyoxal in Adults in a Randomized, Double-Blind, Placebo-Controlled, Crossover Trial with Pure Flavonoids

scientific article published on 01 December 2018

Regulation of angiopoietin-like 4 and lipoprotein lipase in human adipose tissue

scientific article published on 17 February 2018

Responses to high-fat challenges varying in fat type in subjects with different metabolic risk phenotypes: a randomized trial

scientific article

Single nucleotide polymorphisms in the transcobalamin gene: relationship with transcobalamin concentrations and risk for neural tube defects

scientific article published in July 2002

The H475Y polymorphism in the glutamate carboxypeptidase II gene increases plasma folate without affecting the risk for neural tube defects in humans

scientific article published on 01 January 2003

The methionine synthase reductase 66A>G polymorphism is a maternal risk factor for spina bifida.

scientific article

Total homocysteine and its predictors in Dutch children

scientific article published on 01 May 2005

Vascular and inflammatory high fat meal responses in young healthy men; a discriminative role of IL-8 observed in a randomized trial

scientific article

Weight loss moderately affects the mixed meal challenge response of the plasma metabolome and transcriptome of peripheral blood mononuclear cells in abdominally obese subjects

scientific article published on 5 March 2018

Whole Grain Wheat Consumption Affects Postprandial Inflammatory Response in a Randomized Controlled Trial in Overweight and Obese Adults with Mild Hypercholesterolemia in the Graandioos Study

scientific article published on 01 December 2019

List of works by Lydia A Afman

A 12-wk whole-grain wheat intervention protects against hepatic fat: the Graandioos study, a randomized trial in overweight subjects

A high-fat SFA, MUFA, or n3 PUFA challenge affects the vascular response and initiates an activated state of cellular adherence in lean and obese middle-aged men.

A risk assessment-driven quantitative comparison of gene expression profiles in PBMCs and white adipose tissue of humans and rats after isoflavone supplementation

A saturated fatty acid-rich diet induces an obesity-linked proinflammatory gene expression profile in adipose tissue of subjects at risk of metabolic syndrome

A scheme for a flexible classification of dietary and health biomarkers

A short-term intervention with selenium affects expression of genes implicated in the epithelial-to-mesenchymal transition in the prostate

Activation of peroxisome proliferator-activated receptor alpha in human peripheral blood mononuclear cells reveals an individual gene expression profile response

Apolipoprotein E genotype status affects habitual human blood mononuclear cell gene expression and its response to fish oil intervention.

Changes in gene expression in PBMCs profiles of PPARα target genes in obese and non-obese individuals during fasting.

Consumption of a high monounsaturated fat diet reduces oxidative phosphorylation gene expression in peripheral blood mononuclear cells of abdominally overweight men and women.

Dairy proteins, dairy lipids, and postprandial lipemia in persons with abdominal obesity (DairyHealth): a 12-wk, randomized, parallel-controlled, double-blinded, diet intervention study

Dark chocolate consumption improves leukocyte adhesion factors and vascular function in overweight men.

Effect of energy restriction and physical exercise intervention on phenotypic flexibility as examined by transcriptomics analyses of mRNA from adipose tissue and whole body magnetic resonance imaging.

Estrogen receptor-mediated effects of isoflavone supplementation were not observed in whole-genome gene expression profiles of peripheral blood mononuclear cells in postmenopausal, equol-producing women.

Fasting induces changes in peripheral blood mononuclear cell gene expression profiles related to increases in fatty acid beta-oxidation: functional role of peroxisome proliferator activated receptor alpha in human peripheral blood mononuclear cells

Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells.

Gene-gene interaction between the cystathionine beta-synthase 31 base pair variable number of tandem repeats and the methylenetetrahydrofolate reductase 677C > T polymorphism on homocysteine levels and risk for neural tube defects

Genetic variants of FADS gene cluster, plasma LC-PUFA levels and the association with cognitive function of under-two-year-old Sasaknese Indonesian children

Genetic variation in genes of folate metabolism and neural-tube defect risk

Guidelines for Biomarker of Food Intake Reviews (BFIRev): how to conduct an extensive literature search for biomarker of food intake discovery.

High fat challenges with different fatty acids affect distinct atherogenic gene expression pathways in immune cells from lean and obese subjects.

Human nutrigenomics of gene regulation by dietary fatty acids.

Increasing protein intake modulates lipid metabolism in healthy young men and women consuming a high-fat hypercaloric diet

Inhibition of transmethylation disturbs neurulation in chick embryos

Integrated Analys of High-Fat Challenge-Induced Changes in Blood Cell Whole-Genome Gene Expression

Isoflavone supplement composition and equol producer status affect gene expression in adipose tissue: a double-blind, randomized, placebo-controlled crossover trial in postmenopausal women.

Morphogenetic movements during cranial neural tube closure in the chick embryo and the effect of homocysteine.

Nutrigenomics: from molecular nutrition to prevention of disease.

Nutritional aspects of metabolic inflammation in relation to health--insights from transcriptomic biomarkers in PBMC of fatty acids and polyphenols

PUFAs acutely affect triacylglycerol-derived skeletal muscle fatty acid uptake and increase postprandial insulin sensitivity

Phenotyping the effect of diet on non-alcoholic fatty liver disease.

Plasma protein profiling reveals protein clusters related to BMI and insulin levels in middle-aged overweight subjects

Polymorphisms in the transcobalamin gene: association with plasma homocysteine in healthy individuals and vascular disease patients.

Postprandial dietary lipid-specific effects on human peripheral blood mononuclear cell gene expression profiles.

Postprandial fatty acid specific changes in circulating oxylipins in lean and obese men after high-fat challenge tests.

Pure flavonoid epicatechin and whole genome gene expression profiles in circulating immune cells in adults with elevated blood pressure: A randomised double-blind, placebo-controlled, crossover trial.

Quercetin, but Not Epicatechin, Decreases Plasma Concentrations of Methylglyoxal in Adults in a Randomized, Double-Blind, Placebo-Controlled, Crossover Trial with Pure Flavonoids

Regulation of angiopoietin-like 4 and lipoprotein lipase in human adipose tissue

Responses to high-fat challenges varying in fat type in subjects with different metabolic risk phenotypes: a randomized trial

Single nucleotide polymorphisms in the transcobalamin gene: relationship with transcobalamin concentrations and risk for neural tube defects

The H475Y polymorphism in the glutamate carboxypeptidase II gene increases plasma folate without affecting the risk for neural tube defects in humans

The methionine synthase reductase 66A>G polymorphism is a maternal risk factor for spina bifida.

Total homocysteine and its predictors in Dutch children

Vascular and inflammatory high fat meal responses in young healthy men; a discriminative role of IL-8 observed in a randomized trial

Weight loss moderately affects the mixed meal challenge response of the plasma metabolome and transcriptome of peripheral blood mononuclear cells in abdominally obese subjects

Whole Grain Wheat Consumption Affects Postprandial Inflammatory Response in a Randomized Controlled Trial in Overweight and Obese Adults with Mild Hypercholesterolemia in the Graandioos Study