List of works - Rob Leurs

4-(3-Aminoazetidin-1-yl)pyrimidin-2-amines as High-Affinity Non-imidazole Histamine H3 Receptor Agonists with in Vivo Central Nervous System Activity

scientific article published on 20 November 2019

A Photoswitchable Agonist for the Histamine H3 Receptor, a Prototypic Family A G-Protein-Coupled Receptor

scientific article published on 27 February 2019

A toolbox of molecular photoswitches to modulate the CXCR3 chemokine receptor with light

scientific article published on 23 October 2019

Aminergic GPCR-ligand interactions: A chemical and structural map of receptor mutation data

scientific article published on 27 November 2018

Bioluminescence Resonance Energy Transfer Based G Protein-Activation Assay to Probe Duration of Antagonism at the Histamine H3 Receptor

scientific article published on 30 July 2019

Chemokine Receptor Crystal Structures: What Can Be Learned from Them?

scientific article published on 02 July 2019

Homogeneous, Real-Time NanoBRET Binding Assays for the Histamine H3 and H4 Receptors on Living Cells

scientific article published on 24 September 2018

Identification of Phenylphthalazinones as a New Class of Leishmania infantum Inhibitors

scientific article published on 09 December 2019

Interactions between histamine H3 and dopamine D2 receptors and the implications for striatal function

scientific article (publication date: August 2008)

Label-Free Analysis with Multiple Parameters Separates G Protein-Coupled Receptor Signaling Pathways

scientific article published on 15 October 2020

Lead Optimization of Phthalazinone Phosphodiesterase Inhibitors as Novel Antitrypanosomal Compounds

scientific article published on 26 March 2020

Marked changes in signal transduction upon heteromerization of dopamine D1 and histamine H3 receptors

scientific article

Pharmacological Characterization and Radiolabeling of VUF15485, a High-Affinity Small-Molecule Agonist for the Atypical Chemokine Receptor ACKR3

scientific article published in 2024

Photoswitching the Efficacy of a Small-Molecule Ligand for a Peptidergic GPCR: from Antagonism to Agonism

scientific article published on 06 August 2018

Route to Prolonged Residence Time at the Histamine H1 Receptor: Growing from Desloratadine to Rupatadine

scientific article published on 05 July 2019

Synthesis and Characterization of a Bidirectional Photoswitchable Antagonist Toolbox for Real-Time GPCR Photopharmacology.

scientific article published on 14 March 2018

Targeting a Subpocket in Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal Activity.

scientific article published on 19 April 2018

List of works by Rob Leurs