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List of works by Maikel Wijtmans

4-(3-Aminoazetidin-1-yl)pyrimidin-2-amines as High-Affinity Non-imidazole Histamine H3 Receptor Agonists with in Vivo Central Nervous System Activity

scientific article published on 20 November 2019

4-benzyl-1H-imidazoles with oxazoline termini as histamine H3 receptor agonists

scientific article published on 24 April 2008

A Photoswitchable Agonist for the Histamine H3 Receptor, a Prototypic Family A G-Protein-Coupled Receptor

scientific article published on 27 February 2019

A toolbox of molecular photoswitches to modulate the CXCR3 chemokine receptor with light

scientific article published on 23 October 2019

Alkynamide phthalazinones as a new class of TbrPDEB1 inhibitors

scientific article published on 18 June 2019

Bromo-Cyclobutenaminones as New Covalent UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA) Inhibitors

scientific article published on 03 November 2020

Chemical insights in the concept of hybrid drugs: the antitumor effect of nitric oxide-donating aspirin involves a quinone methide but not nitric oxide nor aspirin

scientific article (publication date: 17 May 2007)

Chemical subtleties in small-molecule modulation of peptide receptor function: the case of CXCR3 biaryl-type ligands

scientific article

Combined CXCR3/CXCR4 measurements are of high prognostic value in chronic lymphocytic leukemia due to negative co-operativity of the receptors

scientific article published on 20 November 2015

Covalent Inhibition of the Histamine H3 Receptor

scientific article published on 11 December 2019

Development of a selective ESI-MS derivatization reagent: synthesis and optimization for the analysis of aldehydes in biological mixtures.

scientific article published in December 2008

Discovery of a new class of non-imidazole oxazoline-based histamine H(3) receptor (H(3)R) inverse agonists

scientific article published on July 2009

En route to new blockbuster anti-histamines: surveying the offspring of the expanding histamine receptor family ⬇️

scientific article published on March 15, 2011

Exploring a pocket for polycycloaliphatic groups in the CXCR3 receptor with the aid of a modular synthetic strategy

scientific article published on 27 February 2009

Exploring the CXCR3 Chemokine Receptor with Small-Molecule Antagonists and Agonists

article

Fragment based lead discovery of small molecule inhibitors for the EPHA4 receptor tyrosine kinase

scientific article

Histamine H3 receptor ligands break ground in a remarkable plethora of therapeutic areas

scientific article published on July 2007

Histamine H3 receptor ligands with a 3-cyclobutoxy motif: a novel and versatile constraint of the classical 3-propoxy linker

article

Identification of Ligand Binding Hot Spots of the Histamine H1 Receptor following Structure-Based Fragment Optimization

scientific article

Identification of overlapping but differential binding sites for the high-affinity CXCR3 antagonists NBI-74330 and VUF11211.

scientific article published on 30 October 2013

Inhibition of autotransporter biogenesis by small molecules

scientific article published on 03 May 2019

Keynote review: histamine H3 receptor antagonists reach out for the clinic

scientific article

Ligand based design of novel histamine H4 receptor antagonists; fragment optimization and analysis of binding kinetics ⬇️

scientific article published on November 11, 2011

Metabolic profiling of ligands for the chemokine receptor CXCR3 by liquid chromatography-mass spectrometry coupled to bioaffinity assessment

scientific article published on 12 July 2015

Modulators of CXCR4 and CXCR7/ACKR3 Function

scientific article published on 23 September 2019

Online fluorescence enhancement assay for the acetylcholine binding protein with parallel mass spectrometric identification

scientific article

Pharmacological characterization of [3H]VUF11211, a novel radiolabeled small-molecule inverse agonist for the chemokine receptor CXCR3

scientific article published on 09 January 2015

Photoswitching the Efficacy of a Small-Molecule Ligand for a Peptidergic GPCR: from Antagonism to Agonism

scientific article published on 06 August 2018

Regiochemistry of the Condensation of 2-Aroyl-cyclohexanones and 2-Cyanoacetamide: 13C-Labeling Studies and Semiempirical MO Calculations ⬇️

scientific article published on August 16, 2012

Route to Prolonged Residence Time at the Histamine H1 Receptor: Growing from Desloratadine to Rupatadine

scientific article published on 05 July 2019

Several down, a few to go: histamine H3receptor ligands making the final push towards the market? ⬇️

scientific article published on October 13, 2011

Synthesis and Characterization of a Bidirectional Photoswitchable Antagonist Toolbox for Real-Time GPCR Photopharmacology.

scientific article published on 14 March 2018

Synthesis, modeling and functional activity of substituted styrene-amides as small-molecule CXCR7 agonists

scientific article published on 27 February 2012

Targeting a Subpocket in Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal Activity.

scientific article published on 19 April 2018

Triazole Ligands Reveal Distinct Molecular Features That Induce Histamine H4Receptor Affinity and Subtly Govern H4/H3Subtype Selectivity

scientific article published on 24 February 2011

Virtual Fragment Screening: Discovery of Histamine H3 Receptor Ligands Using Ligand-Based and Protein-Based Molecular Fingerprints

scientific article published on 03 December 2012

Visible Light Excitation of CdSe Nanocrystals Triggers the Release of Coumarin from Cinnamate Surface Ligands

scholarly article by Maikel Wijtmans et al published September 2006 in Journal of the American Chemical Society

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