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List of works by Christian Kupatt

Adeno-associated viral vector 2.9 thymosin ß4 application attenuates rejection after heart transplantation: results of a preclinical study in the pig.

scientific article published in October 2014

Adjuvant early and late cardioprotective therapy: access to the heart.

scientific article published on 07 February 2012

Aging impairs the neurovascular interface in the heart

scientific article published on 24 August 2023

Agrin Promotes Coordinated Therapeutic Processes Leading to Improved Cardiac Repair in Pigs

scientific article published on 08 June 2020

An angiogenic role for the human peptide antibiotic LL-37/hCAP-18.

scientific article

Angiogenetic potential of Ad2/Hif-1α/VP16 after regional application in a preclinical pig model of chronic ischemia

scientific article published on 01 January 2013

Angiopoietin 2 mediates microvascular and hemodynamic alterations in sepsis

scientific article

AntimiR-21 Prevents Myocardial Dysfunction in a Pig Model of Ischemia/Reperfusion Injury

scientific article published on 01 April 2020

Aortic regurgitation with second versus third-generation balloon-expandable prostheses in patients undergoing transcatheter aortic valve implantation

scientific article published on June 2015

Atherosclerosis and the Capillary Network; Pathophysiology and Potential Therapeutic Strategies

scientific article published on 24 December 2019

Attenuation of cardiac hypertrophy by G-CSF is associated with enhanced migration of bone marrow-derived cells.

scientific article published on 8 March 2015

Author Correction: Consistent success in life-supporting porcine cardiac xenotransplantation

scientific article published on 01 April 2019

Balloon valvuloplasty for treatment of cardiogenic shock in the era of surgical valve replacement and TAVI ⬇️

scientific article published on 04 July 2013

Bivalirudin Versus Heparin Anticoagulation in Transcatheter Aortic Valve Replacement: The Randomized BRAVO-3 Trial

scientific article published on 8 October 2015

Bivalirudin vs Heparin in Patients Who Undergo Transcatheter Aortic Valve Implantation

scientific article published on 26 February 2015

C-terminal variable AGES domain of Thymosin β4: the molecule's primary contribution in support of post-ischemic cardiac function and repair

scientific article published on 5 August 2015

CT-angiography-based evaluation of the aortic annulus for prosthesis sizing in transcatheter aortic valve implantation (TAVI)-predictive value and optimal thresholds for major anatomic parameters

scientific article

Cardioprotective Potential of Thymosin s4 in a Preclinical Pig Model of Ischemia/Reperfusion Injury

Challenging decompensated aortic valve stenosis

scientific article published on 01 September 2018

Consistent success in life-supporting porcine cardiac xenotransplantation

scientific article published on 05 December 2018

Corrigendum: Regulation of monocyte cell fate by blood vessels mediated by Notch signalling.

scientific article published on 3 May 2017

Cotransfection of vascular endothelial growth factor-A and platelet-derived growth factor-B via recombinant adeno-associated virus resolves chronic ischemic malperfusion role of vessel maturation

scientific article published in July 2010

Current concepts and applications of coronary venous retroinfusion

scientific article published in November 2004

Diabetes Mellitus-Induced Microvascular Destabilization in the Myocardium

scientific article published on January 2017

Dynamic Quantitative Iodine Myocardial Perfusion Imaging with Dual-Layer CT using a Porcine Model

scientific article published on 05 November 2019

Early vessel destabilization mediated by Angiopoietin-2 and subsequent vessel maturation via Angiopoietin-1 induce functional neovasculature after ischemia.

scientific article

Early weaning completely eliminates porcine cytomegalovirus from a newly established pig donor facility for xenotransplantation

scientific article published on 01 July 2018

Effectiveness of automated quantification of pulmonary perfused blood volume using dual-energy CTPA for the severity assessment of acute pulmonary embolism

scientific article published on August 2013

Embryonic endothelial progenitor cell-mediated cardioprotection requires Thymosin beta4.

scientific article published on August 2008

Embryonic endothelial progenitor cells expressing a broad range of proangiogenic and remodeling factors enhance vascularization and tissue recovery in acute and chronic ischemia

scientific article published on 11 July 2005

Emergency treatment of decompensated aortic stenosis

scientific article published on 31 May 2017

Endothelial RAGE exacerbates acute postischaemic cardiac inflammation

scientific article published on 2 June 2016

Endothelial nitric oxide synthase overexpression provides a functionally relevant angiogenic switch in hibernating pig myocardium.

scientific article published on 23 March 2007

Evaluating Novel Targets of Ischemia Reperfusion Injury in Pig Models

scientific article published on 25 September 2019

Fibrinolysis for patients with intermediate-risk pulmonary embolism

scientific article published in April 2014

Gene editing enables T-cell engineering to redirect antigen specificity for potent tumor rejection

article

Gene therapy for ischemic heart disease.

scientific article published on 25 March 2011

Genetically encoded Ca2+ -sensor reveals details of porcine endothelial cell activation upon contact with human serum

scientific article published on 14 February 2020

Heart-Specific Knockout of the Mitochondrial Thioredoxin Reductase (Txnrd2) Induces Metabolic and Contractile Dysfunction in the Aging Myocardium

scientific article

Heat shock protein 90 transfection reduces ischemia-reperfusion-induced myocardial dysfunction via reciprocal endothelial NO synthase serine 1177 phosphorylation and threonine 495 dephosphorylation.

scientific article

Heme Oxygenase-1 Gene Therapy Provides Cardioprotection Via Control of Post-Ischemic Inflammation: An Experimental Study in a Pre-Clinical Pig Model

scientific article published on July 2015

Hemodynamic and vascular effects of ventricular sourcing by stent-based ventricle to coronary artery bypass in patients with multivessel disease undergoing coronary artery bypass surgery

scientific article

Impact of Thrombolytic Therapy on the Long-Term Outcome of Intermediate-Risk Pulmonary Embolism

scientific article published on March 2017

Impact of percutaneous closure device type on vascular and bleeding complications after TAVR: A post hoc analysis from the BRAVO-3 randomized trial

scientific article published on 22 May 2019

Impact of pre-existing or new-onset atrial fibrillation on 30-day clinical outcomes following transcatheter aortic valve replacement: Results from the BRAVO 3 randomized trial

scientific article

Impact of transcatheter mitral valve repair using MitraClip on right ventricular remodeling

scientific article published on 13 January 2020

Incomplete echocardiographic recovery at 6 months predicts long-term sequelae after intermediate-risk pulmonary embolism. A post-hoc analysis of the Pulmonary Embolism Thrombolysis (PEITHO) trial

scientific article published on 18 December 2018

Induced pluripotent stem cell derived cardiac models: effects of Thymosin β4

scientific article published on 01 July 2018

Inhibition of microRNA-92a protects against ischemia/reperfusion injury in a large-animal model

scientific article published on 29 July 2013

Integrins synergise to induce expression of the MRTF-A-SRF target gene ISG15 for promoting cancer cell invasion

scientific article published on 12 February 2016

Interplay of cell-cell contacts and RhoA/MRTF-A signaling regulates cardiomyocyte identity.

scientific article

Liposomal Hsp90 cDNA induces neovascularization via nitric oxide in chronic ischemia.

scientific article published in February 2005

MRTF-A controls vessel growth and maturation by increasing the expression of CCN1 and CCN2.

scientific article

Migratory and anti-fibrotic programmes define the regenerative potential of human cardiac progenitors

scientific article published on 12 May 2022

Mitochondrial Thioredoxin Reductase Is Essential for Early Postischemic Myocardial Protection

scientific article published on 05 December 2011

Molecular mechanisms of platelet-mediated leukocyte recruitment during myocardial reperfusion.

scientific article published in September 2002

Monocyte-platelet aggregates affect local inflammation in patients with acute myocardial infarction

scientific article published on 08 April 2019

Myocardial CT perfusion imaging in a large animal model: comparison of dynamic versus single-phase acquisitions

scientific article

Myocardial gene transfer by selective pressure-regulated retroinfusion of coronary veins: comparison with surgical and percutaneous intramyocardial gene delivery

scientific article published in September 2004

Myocardial transfection of hypoxia inducible factor-1alpha via an adenoviral vector during coronary artery bypass grafting. - A multicenter phase I and safety study -.

scientific article published on 10 March 2010

NF kappaB activation in embryonic endothelial progenitor cells enhances neovascularization via PSGL-1 mediated recruitment: novel role for LL37.

scientific article

Percutaneous approach to a stent-based ventricle to coronary vein bypass (venous VPASS): comparison to catheter-based selective pressure-regulated retro-infusion of the coronary vein

scientific article published on 25 February 2005

Preconditioned endothelial progenitor cells reduce formation of melanoma metastases through SPARC-driven cell-cell interactions and endocytosis

scientific article published on 26 May 2011

Pro-Angiogenic Macrophage Phenotype to Promote Myocardial Repair

scientific article published on 01 June 2019

Prognostic Impact of Left Atrial Function Following Transcatheter Mitral Valve Repair

scientific article published on 01 May 2019

Proinflammatory role of inducible nitric oxide synthase in acute hyperoxic lung injury

scientific article

Randomized, controlled trial of ultrasound-assisted catheter-directed thrombolysis for acute intermediate-risk pulmonary embolism

scientific article

Recombinant adeno-associated virus-based gene transfer of cathelicidin induces therapeutic neovascularization preferentially via potent collateral growth

scientific article published in February 2009

Reduction of pacemaker implantation rates after CoreValve® implantation by moderate predilatation.

scientific article published in February 2014

Regulation of monocyte cell fate by blood vessels mediated by Notch signalling.

scientific article published on 31 August 2016

Retroinfusion of embryonic endothelial progenitor cells attenuates ischemia-reperfusion injury in pigs: role of phosphatidylinositol 3-kinase/AKT kinase

scientific article

Retroinfusion-supported stenting in high-risk patients for percutaneous intervention and bypass surgery: results of the prospective randomized myoprotect I study

scientific article published in July 2004

Reverse Cardiac Remodeling After Transcatheter Treatment of Severe Tricuspid Regurgitation Using the Edge-to-Edge MitraClip Technique

scientific article published on 01 April 2019

Role of PARP on iNOS pathway during endotoxin-induced acute lung injury

scientific article

SDF-1 fused to a fractalkine stalk and a GPI anchor enables functional neovascularization

scientific article published in September 2013

Selective Pressure-Regulated Retroinfusion for Gene Therapy Application in Ischemic Heart Disease

scientific article published in January 2017

Selective Pressure-Regulated retroinfusion of fibroblast growth factor-2 into the coronary vein enhances regional myocardial blood flow and function in pigs with chronic myocardial ischemia

scientific article published on 01 September 2003

Selective retroinfusion of GSH and cariporide attenuates myocardial ischemia-reperfusion injury in a preclinical pig model

scientific article published in February 2004

Semi-automatic CT-angiography based evaluation of the aortic annulus in patients prior to TAVR: interchangeability with manual measurements

scientific article published on 05 June 2018

Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy

scientific article published on 27 January 2020

Sonodynamic Therapy of Atherosclerotic Plaques: Breaking the Cycle

scientific article published on 27 January 2020

Sphingosine-1-Phosphate Attenuates Lipopolysaccharide-Induced Pericyte Loss via Activation of Rho-A and MRTF-A

scientific article published on 04 October 2020

Statins Make a Difference in Acute Myocardial Infarction: A Revival

scientific article published on 01 March 2020

Steerable induction of the Thymosin ß4/MRTF-A pathway via AAV-based overexpression induces therapeutic neovascularization

scientific article

Targeting microRNAs for cardiovascular therapeutics in coronary artery disease.

scientific article

The GEF Trio controls endothelial cell size and arterial remodeling downstream of Vegf signaling in both zebrafish and cell models

scientific article published on 21 October 2020

The importance of the Heart Team evaluation before transcatheter aortic valve replacement: Results from the BRAVO-3 trial

scientific article published on 13 January 2020

The vascular compartments of neovascularization: spotlight on the microcirculation

scientific article published on February 2007

Therapeutic angiogenesis/arteriogenesis in the chronic ischemic rabbit hindlimb: effect of venous basic fibroblast growth factor retroinfusion

scientific article published on 01 January 2003

Three-Dimensional Printing of Models for Preoperative Planning and Simulation of Transcatheter Valve Replacement ⬇️

scientific article published on February 1, 2012

Thymosin beta4 is an essential paracrine factor of embryonic endothelial progenitor cell-mediated cardioprotection

scientific article published on 21 April 2008

Thymosin beta4: a key factor for protective effects of eEPCs in acute and chronic ischemia

scientific article published on April 2010

Thymosin β4 Improves Differentiation and Vascularization of EHTs

scientific article

Thymosin β4 attenuates microcirculatory and hemodynamic destabilization in sepsis.

scientific article published on 21 January 2015

Thymosin β4-mediated protective effects in the heart

scientific article published on 01 July 2018

Thymosin-β4-mediated therapeutic neovascularization: role of the PI3K/AKT pathway

scientific article published on 4 February 2015

Transcatheter aortic-valve endocarditis confirmed by transesophageal echocardiography

scientific article published in January 2013

Transcutaneous aortic valve replacement with the Edwards SAPIEN XT and Medtronic CoreValve prosthesis under fluoroscopic guidance and local anaesthesia only.

scientific article published on 23 January 2014

Translational Aspects of Adeno-Associated Virus-Mediated Cardiac Gene Therapy

article

Tβ4 Increases Neovascularization and Cardiac Function in Chronic Myocardial Ischemia of Normo- and Hypercholesterolemic Pigs

scientific article published on 19 June 2018

Usefulness of Clopidogrel Loading in Patients Who Underwent Transcatheter Aortic Valve Implantation (from the BRAVO-3 Randomized Trial)

scientific article published on 10 February 2019

VEGF-B: a more balanced approach toward cardiac neovascularization?

scientific article

VEGF165 transfection decreases postischemic NF-κB-dependent myocardial reperfusion injury in vivo: role of eNOS phosphorylation

article

cAMP-dependent regulation of HCN4 controls the tonic entrainment process in sinoatrial node pacemaker cells

scientific article published on 03 November 2020

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