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List of works by Vladimir J N Bykov

A thiol-bound drug reservoir enhances APR-246-induced mutant p53 tumor cell death

scientific article published on 14 December 2020

APR-246 reactivates mutant p53 by targeting cysteines 124 and 277.

scientific article published on 18 April 2018

Characterization of the p53-rescue drug CP-31398 in vitro and in living cells.

scientific article

Correction: APR-246 reactivates mutant p53 by targeting cysteines 124 and 277

scientific article published on 10 October 2019

Inhibition of the glutaredoxin and thioredoxin systems and ribonucleotide reductase by mutant p53-targeting compound APR-246

scientific article published in Scientific Reports

Mutant p53 rescue and modulation of p53 redox state.

scientific article published on 29 August 2009

Mutant p53 targeting by the low molecular weight compound STIMA-1

scientific article published on 7 March 2008

Mutant p53-dependent growth suppression distinguishes PRIMA-1 from known anticancer drugs: a statistical analysis of information in the National Cancer Institute database.

scientific article

Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells

scientific article published on 15 July 2021

PRIMA-1 reactivates mutant p53 by covalent binding to the core domain

scientific article published on May 2009

Reactivation of mutant p53 and induction of apoptosis in human tumor cells by maleimide analogs.

scientific article published on July 2005

Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.

scientific article

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