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List of works by Muthiah Manoharan

A combinatorial library of lipid-like materials for delivery of RNAi therapeutics

scientific article

Aminooxy Click Chemistry as a Tool for Bis-homo and Bis-hetero Ligand Conjugation to Nucleic Acids

scientific article published in 2022

Crystal structure of Middle East respiratory syndrome coronavirus helicase.

scientific article

Development of lipidoid-siRNA formulations for systemic delivery to the liver

scientific article published on 3 March 2009

Effective RNAi-mediated gene silencing without interruption of the endogenous microRNA pathway

scientific article published on 26 September 2007

Incorporating a Thiophosphate Modification into a Common RNA Tetraloop Motif Causes an Unanticipated Stability Boost

scientific article published on 04 December 2020

Overcoming GNA/RNA base-pairing limitations using isonucleotides improves the pharmacodynamic activity of ESC+ GalNAc-siRNAs

scientific article published on 01 November 2021

Re-Engineering RNA Molecules into Therapeutic Agents

scientific article published on 26 March 2019

Synthesis and Biophysical Characterization of RNAs Containing 2'-Fluorinated Northern Methanocarbacyclic Nucleotides

scientific article published on 20 March 2019

Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells.

scientific article

Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates

scientific article

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