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List of works by Jeffrey P Krischer

A Phase II randomized, placebo-controlled clinical trial of purified isoflavones in modulating steroid hormones in men diagnosed with localized prostate cancer

scientific article published on January 2007

A Randomized, Double-Blind Trial of Abatacept (CTLA-4Ig) for the Treatment of Giant Cell Arteritis

scientific article published on 30 January 2017

A Randomized, Double-Blind Trial of Abatacept (CTLA-4Ig) for the Treatment of Takayasu Arteritis

scientific article published on 30 January 2017

A combined risk score enhances prediction of type 1 diabetes among susceptible children

scientific article published on 07 August 2020

A comparison of the baseline metabolic profiles between Diabetes Prevention Trial-Type 1 and TrialNet Natural History Study participants

scientific article

A longitudinal study of GAD65 and ICA512 autoantibodies during the progression to type 1 diabetes in Diabetes Prevention Trial-Type 1 (DPT-1) participants

scientific article

A method for reporting and classifying acute infectious diseases in a prospective study of young children: TEDDY

scientific article

A model-based approach to sample size estimation in recent onset type 1 diabetes

scientific article published on 16 March 2016

A new approach for diagnosing type 1 diabetes in autoantibody-positive individuals based on prediction and natural history

scientific article

A prospective study of the development of diabetes in relatives of patients with insulin-dependent diabetes

scientific article published on 01 October 1990

A quantitative measure of treatment response in recent-onset type 1 diabetes

scientific article published on 14 May 2020

A risk score for type 1 diabetes derived from autoantibody-positive participants in the diabetes prevention trial-type 1.

scientific article published on 13 November 2007

A rule-based prognostic model for type 1 diabetes by identifying and synthesizing baseline profile patterns

scientific article

Accelerated progression from islet autoimmunity to diabetes is causing the escalating incidence of type 1 diabetes in young children

scientific article

Acceleration of the Loss of the First-Phase Insulin Response During the Progression to Type 1 Diabetes in Diabetes Prevention Trial–Type 1 Participants ⬇️

scientific article published on July 17, 2013

Age and family relationship accentuate the risk of insulin-dependent diabetes mellitus (IDDM) in relatives of patients with IDDM

scientific article published on 01 December 1995

Age at gluten introduction and risk of celiac disease

scientific article

An Anti-CD3 Antibody, Teplizumab, in Relatives at Risk for Type 1 Diabetes

scientific article published on 09 June 2019

Analgesic antipyretic use among young children in the TEDDY study: no association with islet autoimmunity

scientific article

Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset type 1 diabetes: a randomised double-blind trial ⬇️

scientific article published on June 27, 2011

Association Between Early-Life Antibiotic Use and the Risk of Islet or Celiac Disease Autoimmunity

scientific article

Association of Early Exposure of Probiotics and Islet Autoimmunity in the TEDDY Study.

scientific article

Association of Gluten Intake During the First 5 Years of Life With Incidence of Celiac Disease Autoimmunity and Celiac Disease Among Children at Increased Risk

scientific article published on 01 August 2019

Association of class II human histocompatibility leukocyte antigens with rheumatic fever

scientific article published on June 1986

Association of diabetes-related autoantibodies with the incidence of asthma, eczema and allergic rhinitis in the TRIGR randomised clinical trial

scientific article published on 17 June 2020

Autoantibodies and human leucocyte antigen class II in first-degree family members of Mexican-American type 1 diabetic patients

scientific article

B-lymphocyte depletion with rituximab and β-cell function: two-year results

scientific article published on 11 September 2013

Biomarker discovery study design for type 1 diabetes in The Environmental Determinants of Diabetes in the Young (TEDDY) study

scientific article published in July 2014

Breastfeeding patterns of mothers with type 1 diabetes: results from an infant feeding trial

scientific article

Cesarean Section on the Risk of Celiac Disease in the Offspring: The Teddy Study

Co-occurrence of Type 1 Diabetes and Celiac Disease Autoimmunity

scientific article published on 10 October 2017

Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial ⬇️

scientific article published on June 28, 2011

Comparing Beta Cell Preservation Across Clinical Trials in Recent-Onset Type 1 Diabetes

scientific article published on 24 August 2020

Comparison of two insulin assays for first-phase insulin release in type 1 diabetes prediction and prevention studies.

scientific article published on 6 August 2011

Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY Study

scientific article

Correction to: Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: the TEDDY study

scientific article

Costimulation modulation with abatacept in patients with recent-onset type 1 diabetes: follow-up 1 year after cessation of treatment

scientific article published on 02 December 2013

Country-specific birth weight and length in type 1 diabetes high-risk HLA genotypes in combination with prenatal characteristics ⬇️

scientific article published on April 28, 2011

DETECTION OF LACTOBACILLI IN MONTHLY MAIL-IN STOOL SAMPLES FROM 3-18 MONTHS OLD INFANTS AT GENETIC RISK FOR TYPE 1 DIABETES.

scientific article

Data Mining Framework For Discovering and Clustering Phenotypes of Atypical Diabetes

scientific article published in 2022

Development of autoantibodies in the TrialNet Natural History Study

scientific article

Dietary intake of soluble fiber and risk of islet autoimmunity by 5 y of age: results from the TEDDY study.

scientific article

Distinct Growth Phases in Early Life Associated With the Risk of Type 1 Diabetes: The TEDDY Study

scientific article published on 02 January 2020

Distribution of C-peptide and its determinants in North American children at risk for type 1 diabetes

scientific article

Do Electrochemiluminescence Assays Improve Prediction of Time to Type 1 Diabetes in Autoantibody-Positive TrialNet Subjects?

scientific article published on 25 July 2016

Early Infant Diet and Islet Autoimmunity in the TEDDY Study

scientific article published on 17 January 2018

Early Probiotic Supplementation and the Risk of Celiac Disease in Children at Genetic Risk

scientific article published on 02 August 2019

Early childhood gut microbiomes show strong geographic differences among subjects at high risk for type 1 diabetes

scientific article

Early diagnosis and specific treatment of insulin-dependent diabetes

scientific article published on November 1993

Early feeding and risk of type 1 diabetes: experiences from the Trial to Reduce Insulin-dependent diabetes mellitus in the Genetically at Risk (TRIGR).

scientific article

Effect of Hydrolyzed Infant Formula vs Conventional Formula on Risk of Type 1 Diabetes: The TRIGR Randomized Clinical Trial

scientific article published in January 2018

Effect of Oral Insulin on Prevention of Diabetes in Relatives of Patients With Type 1 Diabetes: A Randomized Clinical Trial

scientific article published in November 2017

Effect of docosahexaenoic acid supplementation on inflammatory cytokine levels in infants at high genetic risk for type 1 diabetes

scientific article

Effects of oral insulin in relatives of patients with type 1 diabetes: The Diabetes Prevention Trial--Type 1.

scientific article published in May 2005

Electrochemiluminescence assays for insulin and glutamic acid decarboxylase autoantibodies improve prediction of type 1 diabetes risk

scientific article

Erratum. Validation of the Diabetes Prevention Trial-Type 1 Risk Score in the TrialNet Natural History Study. Diabetes Care 2011;34:1785-1787.

scientific article published on 23 February 2018

Erratum. Who Is Enrolling? The Path to Monitoring in Type 1 Diabetes TrialNet's Pathway to Prevention. Diabetes Care 2019;42:2228-2236

scientific article published on 04 March 2020

Experience With Direct-to-Patient Recruitment for Enrollment Into a Clinical Trial in a Rare Disease: A Web-Based Study.

scientific article published on 28 February 2017

Expression of GAD65 and islet cell antibody (ICA512) autoantibodies among cytoplasmic ICA+ relatives is associated with eligibility for the Diabetes Prevention Trial-Type 1.

scientific article published in August 2001

Expression of beta-cell autoimmunity does not differ between potential dizygotic twins and siblings of patients with type 1 diabetes

scientific article published on 01 November 2004

Factors Associated with Decline of C-peptide in a Cohort of Young Children Diagnosed with Type 1 Diabetes

scientific article published on 09 October 2020

Factors That Increase Risk of Celiac Disease Autoimmunity After a Gastrointestinal Infection in Early Life

scientific article

Factors associated with longitudinal food record compliance in a paediatric cohort study.

scientific article

Family adjustment to diabetes diagnosis in children: Can participation in a study on type 1 diabetes genetic risk be helpful?

scientific article published on 26 March 2018

Feature ranking based on synergy networks to identify prognostic markers in DPT-1.

scientific article published on 19 September 2013

First Infant Formula Type and Risk of Islet Autoimmunity in The Environmental Determinants of Diabetes in the Young (TEDDY) Study

scientific article published on 17 January 2017

First test effect in intravenous glucose tolerance testing ⬇️

scientific article published on August 15, 2013

First-phase insulin release during the intravenous glucose tolerance test as a risk factor for type 1 diabetes

scientific article

GAD65 autoantibodies increase the predictability but not the sensitivity of islet cell and insulin autoantibodies for developing insulin dependent diabetes mellitus

scientific article published on 01 December 1994

Genetic Contribution to the Divergence in Type 1 Diabetes Risk Between Children From the General Population and Children From Affected Families

scientific article published on 17 January 2019

Genetic and Environmental Interactions Modify the Risk of Diabetes-Related Autoimmunity by 6 Years of Age: The TEDDY Study

scientific article

Genetic scores to stratify risk of developing multiple islet autoantibodies and type 1 diabetes: A prospective study in children.

scientific article published on 3 April 2018

Gestational respiratory infections interacting with offspring HLA and CTLA-4 modifies incident β-cell autoantibodies

scientific article published on 20 September 2017

Glucose and C-peptide changes in the perionset period of type 1 diabetes in the Diabetes Prevention Trial-Type 1.

scientific article published on 23 July 2008

Glucose excursions between states of glycemia with progression to type 1 diabetes in the diabetes prevention trial-type 1 (DPT-1).

scientific article

Growth and Risk for Islet Autoimmunity and Progression to Type 1 Diabetes in Early Childhood: The Environmental Determinants of Diabetes in the Young Study

scientific article published on 18 March 2016

HLA-DPB1*04:01 Protects Genetically Susceptible Children from Celiac Disease Autoimmunity in the TEDDY Study

scientific article

Harmonization of glutamic acid decarboxylase and islet antigen-2 autoantibody assays for national institute of diabetes and digestive and kidney diseases consortia

scientific article

Heart failure as a risk factor for diabetes mellitus

scientific article published on 19 August 2014

Hierarchical Order of Distinct Autoantibody Spreading and Progression to Type 1 Diabetes in the TEDDY Study

scientific article published on 08 July 2020

High frequency of abnormal glucose tolerance in DQA1*0102/DQB1*0602 relatives identified as part of the Diabetes Prevention Trial--Type 1 Diabetes

scientific article

How to Measure Secondhand Smoke Exposure in a Pediatric Clinic Setting ⬇️

scientific article published on 01 July 2011

Hydrolyzed infant formula and early β-cell autoimmunity: a randomized clinical trial

scientific article

Identification of Non-HLA Genes Associated with Celiac Disease and Country-Specific Differences in a Large, International Pediatric Cohort

scientific article

Identification of non-HLA genes associated with development of islet autoimmunity and type 1 diabetes in the prospective TEDDY cohort

scientific article published on 5 January 2018

Incident dysglycemia and progression to type 1 diabetes among participants in the Diabetes Prevention Trial-Type 1

scientific article published on June 2009

Increasing the accuracy of oral glucose tolerance testing and extending its application to individuals with normal glucose tolerance for the prediction of type 1 diabetes: the Diabetes Prevention Trial-Type 1.

scientific article published in January 2007

Influence of fecal sample storage on bacterial community diversity.

scientific article published on 24 March 2009

Insulin and islet cell autoantibodies as time-dependent covariates in the development of insulin-dependent diabetes: a prospective study in relatives

scientific article published in September 1993

Insulin immunization of nonobese diabetic mice induces a protective insulitis characterized by diminished intraislet interferon-gamma transcription

scientific article

Intake of Energy and Protein is Associated with Overweight Risk at Age 5.5 Years: Results from the Prospective TEDDY Study

scientific article

Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials ⬇️

scientific article published on 05 April 2013

Introducing the Endotype Concept to Address the Challenge of Disease Heterogeneity in Type 1 Diabetes

scientific article published on 21 November 2019

Islet autoantibody seroconversion in the DPT-1 study: justification for repeat screening throughout childhood

scientific article

Islet cell antibodies predict insulin-dependent diabetes in United States school age children as powerfully as in unaffected relatives

scientific article

Islet cell antibody-positive relatives with human leukocyte antigen DQA1*0102, DQB1*0602: identification by the Diabetes Prevention Trial-type 1

scientific article published on 01 March 2000

Joint modeling of longitudinal autoantibody patterns and progression to type 1 diabetes: results from the TEDDY study

scientific article published on 30 August 2017

Large-scale prospective T cell function assays in shipped, unfrozen blood samples: experiences from the multicenter TRIGR trial

scientific article published on 11 December 2013

Long-term outcome of individuals treated with oral insulin: diabetes prevention trial-type 1 (DPT-1) oral insulin trial

scientific article

Longitudinal Metabolome-Wide Signals Prior to the Appearance of a First Islet Autoantibody in Children Participating in the TEDDY Study

scientific article published on 06 February 2020

Low-Dose Anti-Thymocyte Globulin (ATG) Preserves β-Cell Function and Improves HbA in New-Onset Type 1 Diabetes

article

Low-Dose Anti-Thymocyte Globulin Preserves C-Peptide, Reduces HbA1c, and Increases Regulatory to Conventional T-Cell Ratios in New-Onset Type 1 Diabetes: Two-Year Clinical Trial Data

scientific article published on 09 April 2019

Male sex increases the risk of autoimmunity but not type 1 diabetes

scientific article

Maternal Dietary Supplement Use and Development of Islet Autoimmunity in the offspring: the TEDDY Study

article

Maternal use of dietary supplements during pregnancy is not associated with coeliac disease in the offspring: The Environmental Determinants of Diabetes in the Young (TEDDY) study

scientific article

Metabolic tests to determine risk for type 1 diabetes in clinical trials ⬇️

scientific article published on September 1, 2011

Metabolite-related dietary patterns and the development of islet autoimmunity

scientific article published on 15 October 2019

Metagenomics of the faecal virome indicate a cumulative effect of enterovirus and gluten amount on the risk of coeliac disease autoimmunity in genetically at risk children: the TEDDY study

scientific article published on 19 November 2019

Methods, quality control and specimen management in an international multicentre investigation of type 1 diabetes: TEDDY

scientific article published on October 2013

Multiple autoantibodies as predictors of Type 1 diabetes in a general population

scientific article published on 11 June 2003

Nested case-control data analysis using weighted conditional logistic regression in The Environmental Determinants of Diabetes in the Young (TEDDY) study: A novel approach

scientific article published on 31 July 2019

Next-generation sequencing for viruses in children with rapid-onset type 1 diabetes

scientific article

Only multiple autoantibodies to islet cells (ICA), insulin, GAD65, IA-2 and IA-2beta predict immune-mediated (Type 1) diabetes in relatives

scientific article published on 01 June 1999

Oral insulin therapy to prevent progression of immune-mediated (type 1) diabetes

scientific article published on 01 December 2004

Pancreatic islet autoantibodies as predictors of type 1 diabetes in the Diabetes Prevention Trial-Type 1.

scientific article published on 09 September 2009

Pandemrix® vaccination is not associated with increased risk of islet autoimmunity or type 1 diabetes in the TEDDY study children

scientific article published on 9 October 2017

Patterns of metabolic progression to type 1 diabetes in the Diabetes Prevention Trial-Type 1.

scientific article published in March 2006

Performance of HbA1c as an Early Diagnostic Indicator of Type 1 Diabetes in Children and Youth ⬇️

scientific article published on June 14, 2012

Plasma 25-Hydroxyvitamin D Concentration and Risk of Islet Autoimmunity

scientific article published on 23 October 2017

Plasma Metabolome and Circulating Vitamins Stratified Onset Age of an Initial Islet Autoantibody and Progression to Type 1 Diabetes: the TEDDY Study

scientific article published on 26 October 2020

Plasma ascorbic acid and the risk of islet autoimmunity and type 1 diabetes: the TEDDY study

scientific article published on 14 November 2019

Pre-type 1 diabetes dysmetabolism: maximal sensitivity achieved with both oral and intravenous glucose tolerance testing

scientific article published on January 2007

Predicting Islet Cell Autoimmunity and Type 1 Diabetes: An 8-Year TEDDY Study Progress Report

scientific article published on 09 April 2019

Predicting progression to type 1 diabetes from ages 3 to 6 in islet autoantibody positive TEDDY children

scientific article published on 29 January 2019

Predictors of Progression From the Appearance of Islet Autoantibodies to Early Childhood Diabetes: The Environmental Determinants of Diabetes in the Young (TEDDY).

scientific article published on 9 February 2015

Preservation of C-peptide secretion in subjects at high risk of developing type 1 diabetes mellitus--a new surrogate measure of non-progression?

scientific article

Prevalence of obesity was related to HLA-DQ in 2-4-year-old children at genetic risk for type 1 diabetes

scientific article

Prognostic Classification Factors Associated With Development of Multiple Autoantibodies, Dysglycemia, and Type 1 Diabetes-A Recursive Partitioning Analysis

scientific article

Prognostic accuracy of immunologic and metabolic markers for type 1 diabetes in a high-risk population: receiver operating characteristic analysis

scientific article

Prognostic performance of metabolic indexes in predicting onset of type 1 diabetes

scientific article

Progression from islet autoimmunity to clinical type 1 diabetes is influenced by genetic factors: results from the prospective TEDDY study

article

Prospective virome analyses in young children at increased genetic risk for type 1 diabetes

scientific article published on 02 December 2019

Psychological Manifestations of Celiac Disease Autoimmunity in Young Children

scientific article

Randomized Trial of Lisinopril Versus Carvedilol to Prevent Trastuzumab Cardiotoxicity in Patients With Breast Cancer

scientific article published on 01 June 2019

Regional differences in milk and complementary feeding patterns in infants participating in an international nutritional type 1 diabetes prevention trial

scientific article published on 7 October 2016

Relative validity of a dietary interview for assessing infant diet and compliance in a dietary intervention trial

scientific article published in July 2006

Residual beta-cell function in diabetes children followed and diagnosed in the TEDDY study compared to community controls

scientific article published on 27 January 2017

Respiratory infections are temporally associated with initiation of type 1 diabetes autoimmunity: the TEDDY study

scientific article published on 2 August 2017

Reversion of β-Cell Autoimmunity Changes Risk of Type 1 Diabetes: TEDDY Study

scientific article published on 16 June 2016

Role of Type 1 Diabetes-Associated SNPs on Risk of Autoantibody Positivity in the TEDDY Study

scientific article

Role of insulin resistance in predicting progression to type 1 diabetes

scientific article published on 29 May 2007

Safety and efficacy of autoantigen-specific therapy with 2 doses of alum-formulated glutamate decarboxylase in children with multiple islet autoantibodies and risk for type 1 diabetes: A randomized clinical trial

scientific article published on 24 November 2017

Safety of purified isoflavones in men with clinically localized prostate cancer

scientific article published on January 2007

Screening strategies for the identification of multiple antibody-positive relatives of individuals with type 1 diabetes

scientific article published on 01 January 2003

Serum 25-hydroxyvitamin D concentration in childhood and risk of islet autoimmunity and type 1 diabetes: the TRIGR nested case-control ancillary study

scientific article published on 07 January 2020

Specific human leukocyte antigen DQ influence on expression of antiislet autoantibodies and progression to type 1 diabetes

scientific article published on 07 February 2006

Staging presymptomatic type 1 diabetes: a scientific statement of JDRF, the Endocrine Society, and the American Diabetes Association

scientific article published on October 2015

Strength in Numbers: Opportunities for Enhancing the Development of Effective Treatments for Type 1 Diabetes-The TrialNet Experience

scientific article published on 16 May 2018

TEDDY--The Environmental Determinants of Diabetes in the Young: an observational clinical trial

scientific article published on 01 October 2006

Temporal changes in gastrointestinal fungi and the risk of autoimmunity during early childhood: the TEDDY study

scientific article published on 01 January 2022

Temporal development of the gut microbiome in early childhood from the TEDDY study

scientific article published in Nature

Teplizumab in Relatives at Risk for Type 1 Diabetes. Reply

scientific article published on 01 November 2019

The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study

scientific article

The Effect of DPT-1 Intravenous Insulin Infusion and Daily Subcutaneous Insulin on Endogenous Insulin Secretion and Postprandial Glucose Tolerance

scientific article published on 26 February 2015

The Environmental Determinants of Diabetes in the Young (TEDDY) Study: 2018 Update

article

The Environmental Determinants of Diabetes in the Young (TEDDY): genetic criteria and international diabetes risk screening of 421 000 infants

scientific article published on 12 May 2011

The Influence of Type 1 Diabetes Genetic Susceptibility Regions, Age, Sex, and Family History on the Progression From Multiple Autoantibodies to Type 1 Diabetes: A TEDDY Study Report

scientific article published on 13 September 2017

The Prediction of Type 1 Diabetes by Multiple Autoantibody Levels and Their Incorporation Into an Autoantibody Risk Score in Relatives of Type 1 Diabetic Patients ⬇️

scientific article published on July 1, 2013

The TRIGR Trial: Testing the Potential Link between Weaning Diet and Type 1 Diabetes

The Trial to Reduce IDDM in the Genetically at Risk (TRIGR) study: recruitment, intervention and follow-up ⬇️

scientific article published on December 12, 2010

The Use of Electrochemiluminescence Assays to Predict Autoantibody and Glycemic Progression Toward Type 1 Diabetes in Individuals with Single Autoantibodies

scientific article published on 8 February 2017

The application of the diabetes prevention trial-type 1 risk score for identifying a preclinical state of type 1 diabetes

scientific article

The development and utility of a novel scale that quantifies the glycemic progression toward type 1 diabetes over 6 months

scientific article

The human gut microbiome in early-onset type 1 diabetes from the TEDDY study

scientific article published in Nature

The implications of autoantibodies to a single islet antigen in relatives with normal glucose tolerance: development of other autoantibodies and progression to type 1 diabetes

scientific article published on 16 December 2015

The use of intermediate endpoints in the design of type 1 diabetes prevention trials ⬇️

scientific article published on 07 June 2013

Therapeutic controversy: prevention and treatment of diabetes in children

scientific article

Thyroid function in the etiology of fatigue in breast cancer.

scientific article published on 22 May 2018

Time-Resolved Autoantibody Profiling Facilitates Stratification of Preclinical Type 1 Diabetes in Children

article

To screen or not to screen for pre-type 1 diabetes?

scientific article

Trends of earlier and later responses of C-peptide to oral glucose challenges with progression to type 1 diabetes in diabetes prevention trial-type 1 participants

scientific article

Type I diabetes manifested solely by 2-h oral glucose tolerance test criteria

scientific article

Use of the Diabetes Prevention Trial-Type 1 Risk Score (DPTRS) for improving the accuracy of the risk classification of type 1 diabetes

scientific article

Use of vitamin D supplements during infancy in an international feeding trial

scientific article

Validation of the Diabetes Prevention Trial-Type 1 Risk Score in the TrialNet Natural History Study

scientific article

Who Is Enrolling? The Path to Monitoring in Type 1 Diabetes TrialNet's Pathway to Prevention

scientific article published on 26 September 2019

Zinc Transporter-8 Autoantibodies Improve Prediction of Type 1 Diabetes in Relatives Positive for the Standard Biochemical Autoantibodies ⬇️

scientific article published on March 23, 2012

β Cell dysfunction exists more than 5 years before type 1 diabetes diagnosis

β cell death and dysfunction during type 1 diabetes development in at-risk individuals

scientific article

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