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List of works by Andrew D Cherniack

A Comprehensive Pan-Cancer Molecular Study of Gynecologic and Breast Cancers

scientific article published in April 2018

A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily

scientific article published on 26 September 2018

A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1

scientific article

Abstract 3890: Sequencing of 888 pediatric solid tumors informs precision oncology trial design and data sharing initiatives in pediatric cancer

scientific article published in 2022

Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors

scientific article published on 27 September 2013

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

scientific article published in April 2018

Analytical protocol to identify local ancestry-associated molecular features in cancer

scientific article published on 20 September 2021

Ancestry-specific predisposing germline variants in cancer

scientific article published on 29 May 2020

Author Correction: Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells

correction of a scholarly article

BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II-DNA complexes

article published in the Proceedings of the National Academy of Sciences of the United States of America

Before and After: Comparison of Legacy and Harmonized TCGA Genomic Data Commons' Data

scientific article published on 01 July 2019

Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer

scientific article published in April 2018

Clinicopathological and genomic correlates of Programmed Cell Death Ligand 1 (PD-L1) expression in nonsquamous non-small cell lung cancer

scientific article published on 11 March 2020

Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas

scientific article published on 2 April 2018

Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas

scientific article published on 4 May 2017

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

article

Comprehensive Analysis of Genetic Ancestry and Its Molecular Correlates in Cancer

scientific article published on 01 May 2020

Comprehensive Characterization of Cancer Driver Genes and Mutations

article

Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer

scientific article

Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer

scientific article published on 01 August 2018

Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma

scientific article published on 4 November 2015

Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer

scientific article

Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma

scientific article

Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma

article

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas

scientific article

Correction: Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12

scientific article published on 01 November 2020

Corrigendum: Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth

scientific article published on 30 June 2017

Corrigendum: Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth

scientific article published on 24 June 2016

DNA defects, epigenetics, and gene expression in cancer-adjacent breast: a study from The Cancer Genome Atlas

scientific article

Distinct patterns of somatic genome alterations in lung adenocarcinomas and squamous cell carcinomas

scientific article

Endometrial Carcinoma Recurrence Score (ECARS) validates to identify aggressive disease and associates with markers of epithelial-mesenchymal transition and PI3K alterations

scientific article published in July 2014

Functional comparison of recombinant acidic mammalian chitinase with enzyme from murine bronchoalveolar lavage

scientific article published on September 6, 2010

GENO-06A PAN-GLIOMA CHARACTERIZATION OF GENOMIC, EPIGENOMIC AND TRANSCRIPTOMIC ACTIVITIES REVEALS NOVEL RELATIONSHIPS BETWEEN HISTOLOGICAL SUBTYPES AND MOLECULAR SIGNATURES.

scientific article

Genetic clues can be used to predict whether early-stage cancer will form an invasive tumour

scientific article published on 01 February 2019

Genetic modifiers of EGFR dependence in non-small cell lung cancer

scientific article

Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer

scientific article published on 28 June 2018

Genomic Activation of PPARG Reveals a Candidate Therapeutic Axis in Bladder Cancer

scientific article published on 18 September 2017

Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting

scientific article published on 3 June 2016

Genomic and Functional Approaches to Understanding Cancer Aneuploidy

scientific article published on 31 March 2018

Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas

scientific article published in April 2018

Genomic and immune profiling of pre-invasive lung adenocarcinoma

scientific article published on 29 November 2019

Genomic characterization of de novo metastatic breast cancer

scientific article published on 08 December 2020

Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

scientific article published in April 2018

Glioblastoma-derived epidermal growth factor receptor carboxyl-terminal deletion mutants are transforming and are sensitive to EGFR-directed therapies

scientific article published on 14 October 2011

Identification of ADAR1 adenosine deaminase dependency in a subset of cancer cells

scientific article published in Nature Communications

Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers

scientific article

Impact of DNA damage response and repair (DDR) gene mutations on efficacy of PD-(L)1 immune checkpoint inhibition in non-small cell lung cancer

scientific article published on 24 April 2020

Integrated Genomic and Functional microRNA Analysis Identifies miR-30-5p as a Tumor Suppressor and Potential Therapeutic Nanomedicine in Head and Neck Cancer

scientific article published on 05 February 2019

Integrated Molecular Characterization of Testicular Germ Cell Tumors

article by Hui Shen et al published 12 June 2018 in Cell Reports

Integrated Molecular Characterization of Uterine Carcinosarcoma

scientific article

Integrated genomic characterization of endometrial carcinoma

scientific article published on May 2, 2013

Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma

scientific article published on August 2017

Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma

scientific article

Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles

scientific article

Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles

article

Integrative Molecular Characterization of Malignant Pleural Mesothelioma

scientific article published on 15 October 2018

Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma

scientific article published on 29 May 2020

Landscape of genomic alterations in cervical carcinomas

scientific article

Loss of heterozygosity of essential genes represents a widespread class of potential cancer vulnerabilities

scientific article published on 20 May 2020

Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1

scientific article

Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas

scientific article published in April 2018

Mammalian SWI/SNF complex genomic alterations and immune checkpoint blockade in solid tumors

scientific article published on 22 April 2020

Mechanisms and therapeutic implications of hypermutation in gliomas

scientific article published on 15 April 2020

Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12

scientific article published on 31 January 2020

Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer

scientific article published on 01 December 2021

Molecular Characterization and Therapeutic Targeting of Colorectal Cancers Harboring Receptor Tyrosine Kinase Fusions

scientific article published on 07 January 2021

Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma

scientific article published on January 2016

Molecular mechanisms of acquired resistance to MET tyrosine kinase inhibitors in patients with MET exon 14 mutant NSCLC

scientific article published on 07 February 2020

Molecular profiling of endometrial carcinoma precursor, primary and metastatic lesions suggests different targets for treatment in obese compared to non-obese patients

scientific article

Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin

scientific article

Near haploidization is a genomic hallmark which defines a molecular subgroup of giant cell glioblastoma

scientific article published on 01 January 2020

Next-generation characterization of the Cancer Cell Line Encyclopedia

scientific article published on 08 May 2019

Oncogenic Signaling Pathways in The Cancer Genome Atlas

scientific article published in April 2018

PIK3CA Amplification Associates with Aggressive Phenotype but Not Markers of AKT-MTOR Signaling in Endometrial Carcinoma

scientific article published on 15 November 2018

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

scientific article published in March 2018

Pathogenic Germline Variants in 10,389 Adult Cancers

scientific article published in April 2018

Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics

scientific article published in April 2018

Pooled Genomic Screens Identify Anti-apoptotic Genes as Targetable Mediators of Chemotherapy Resistance in Ovarian Cancer

scientific article published on 28 August 2019

Quantification of aneuploidy in targeted sequencing data using ASCETS

scientific article published on 28 November 2020

RPC4046, A Novel Anti-interleukin-13 Antibody, Blocks IL-13 Binding to IL-13 α1 and α2 Receptors: A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation First-in-Human Study

scientific article

Rapid Intraoperative Molecular Characterization of Glioma

scientific article published on 14 May 2015

Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth

scientific article published on 10 May 2016

Somatic Superenhancer Duplications and Hotspot Mutations Lead to Oncogenic Activation of the KLF5 Transcription Factor.

scientific article published on 29 September 2017

Sporadic Early-Onset Diffuse Gastric Cancers Have High Frequency of Somatic CDH1 Alterations, but Low Frequency of Somatic RHOA Mutations Compared With Late-Onset Cancers.

scientific article published on 15 May 2017

Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase

scientific article published on 16 July 2021

Suppression of oxidative metabolism and mitochondrial biogenesis by the transcriptional corepressor RIP140 in mouse adipocytes.

scientific article

Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q

scientific article published on 01 December 2020

Targetable vulnerabilities in T- and NK-cell lymphomas identified through preclinical models.

scientific article published on 22 May 2018

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

article

The Immune Landscape of Cancer

scientific article published on 4 April 2018

The Immune Landscape of Cancer

scientific article published on 01 August 2019

The Integrated Genomic Landscape of Thymic Epithelial Tumors

scientific article published in February 2018

The genomic landscape and evolution of endometrial carcinoma progression and abdominopelvic metastasis

scientific article published on 27 June 2016

The genomic landscape of tuberous sclerosis complex

scientific article

The somatic genomic landscape of chromophobe renal cell carcinoma

scientific article (publication date: 8 September 2014)

Whole-genome characterization of lung adenocarcinomas lacking the RTK/RAS/RAF pathway

scientific article published on 2 February 2021