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List of works by Hardy Kornfeld

"The Impact of Mycobacterium tuberculosis Immune Evasion on Protective Immunity: Implications for TB Vaccine Design" - Meeting report

scientific article published on 2 May 2017

A Common NLRC4 Gene Variant Associates With Inflammation and Pulmonary Function in Human Immunodeficiency Virus and Tuberculosis

scientific article published on 22 November 2019

A Common Variant in the Adaptor Mal Regulates Interferon Gamma Signaling.

scientific article published on February 2016

An ounce of tuberculosis prevention

scientific article published in April 2008

Apoptosis genes in human alveolar macrophages infected with virulent or attenuated Mycobacterium tuberculosis: a pivotal role for tumor necrosis factor

scientific article published on 14 May 2003

Association of Plasma Matrix Metalloproteinase and Tissue Inhibitors of Matrix Metalloproteinase Levels With Adverse Treatment Outcomes Among Patients With Pulmonary Tuberculosis

scientific article published on 01 December 2020

Autophagy Controls IL-1β Secretion by Targeting Pro-IL-1β for Degradation

scientific article published on January 12, 2011

Autophagy induction by silver nanowires: a new aspect in the biocompatibility assessment of nanocomposite thin films

scientific article published on 31 August 2012

Bacillary replication and macrophage necrosis are determinants of neutrophil recruitment in tuberculosis

scientific article published on 7 April 2015

Beta-chemokines are induced by Mycobacterium tuberculosis and inhibit its growth

scientific article published on April 2002

CD4 T-cell-mediated heterologous immunity between mycobacteria and poxviruses

scientific article published on 04 February 2009

CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance

scientific article published on 02 February 2009

CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance.

scientific article

CD8+ T lymphocytes regulate the arteriogenic response to ischemia by infiltrating the site of collateral vessel development and recruiting CD4+ mononuclear cells through the expression of interleukin-16.

scientific article published on 27 December 2005

Cell death and autophagy in tuberculosis

scientific article

Chromatin decondensation and T cell hyperresponsiveness in diabetes-associated hyperglycemia

scientific article

Coincident pre-diabetes is associated with dysregulated cytokine responses in pulmonary tuberculosis

scientific article

Declines in Lung Function After Antiretroviral Therapy Initiation in Adults With Human Immunodeficiency Virus and Tuberculosis: A Potential Manifestation of Respiratory Immune Reconstitution Inflammatory Syndrome

scientific article published on 01 April 2020

Defects in early cell recruitment contribute to the increased susceptibility to respiratory Klebsiella pneumoniae infection in diabetic mice.

scientific article

Defining a research agenda to address the converging epidemics of tuberculosis and diabetes. Part 1: Epidemiology and clinical management

scientific article

Defining a research agenda to address the converging epidemics of tuberculosis and diabetes. Part 2: Underlying biological mechanisms

scientific article

Diabetes Is Associated with Worse Clinical Presentation in Tuberculosis Patients from Brazil: A Retrospective Cohort Study

scientific article published on 11 January 2016

Diabetes and immunity to tuberculosis

scientific article

Diabetic mice display a delayed adaptive immune response to Mycobacterium tuberculosis

scientific article

Differential adjuvant activities of TLR7 and TLR9 agonists inversely correlate with nitric oxide and PGE2 production

scientific article

Discriminating Active Tuberculosis from Latent Tuberculosis Infection by flow cytometric measurement of CD161-expressing T cells.

scientific article

Effect of standard tuberculosis treatment on naive, memory and regulatory T-cell homeostasis in tuberculosis-diabetes co-morbidity

scientific article published on 11 June 2016

Elevated circulating levels of monocyte activation markers among tuberculosis patients with diabetes co-morbidity

scientific article published on 10 December 2018

Elevated levels of matrix metalloproteinases reflect severity and extent of disease in tuberculosis-diabetes co-morbidity and are predominantly reversed following standard anti-tuberculosis or metformin treatment.

scientific article

Empirical treatment with non-anti-tuberculosis antibiotics decreased microbiological detection in cervical tuberculous lymphadenitis

scientific article published on 20 June 2018

Engrafted human cells generate adaptive immune responses to Mycobacterium bovis BCG infection in humanized mice

scientific article

Enhancement of antimycobacterial activity of macrophages by stabilization of inner mitochondrial membrane potential

scientific article

Enlisting the Host to Fight TB

scientific article published on 01 June 2018

Epitope-driven TB vaccine development: a streamlined approach using immuno-informatics, ELISpot assays, and HLA transgenic mice

scientific article published in June 2007

Gamma interferon immunospot assay of pleural effusion mononuclear cells for diagnosis of tuberculous pleurisy

scientific article published on 03 January 2014

Glucose Metabolism Disorder Is Associated with Pulmonary Tuberculosis in Individuals with Respiratory Symptoms from Brazil

scientific article

Heightened circulating levels of antimicrobial peptides in tuberculosis-Diabetes co-morbidity and reversal upon treatment.

scientific article published on 14 September 2017

Heterogeneity in the cytokine profile of tuberculosis - diabetes co-morbidity

scientific article published on 28 August 2019

High Prevalence and Heterogeneity of Diabetes in Patients With TB in South India: A Report from the Effects of Diabetes on Tuberculosis Severity (EDOTS) Study

scientific article published on 10 March 2016

Histamine 4 receptor activation induces recruitment of FoxP3+ T cells and inhibits allergic asthma in a murine model

scientific article published in June 2007

Host sirtuin 1 regulates mycobacterial immunopathogenesis and represents a therapeutic target against tuberculosis

scientific article

Hypercholesterolemia impairs immunity to tuberculosis

scientific article published on 27 May 2008

Hypercholesterolemic LDL receptor-deficient mice mount a neutrophilic response to tuberculosis despite the timely expression of protective immunity

scientific article published on January 6, 2012

IL-16 promotes T. whipplei replication by inhibiting phagosome conversion and modulating macrophage activation

scientific article published on October 21, 2010

IL-16/miR-125a axis controls neutrophil recruitment in pristane-induced lung inflammation

IP-10 and MIG are compartmentalized at the site of disease during pleural and meningeal tuberculosis and are decreased after antituberculosis treatment

scientific article

Immunome-derived Epitope-driven Vaccines (ID-EDV) Protect against Viral or Bacterial Challenge in Humanized Mice

Immunomodulatory effect of interleukin-16 on allergic airway inflammation.

scientific article

Impact of Diabetes and Low Body Mass Index on Tuberculosis Treatment Outcomes

scientific article published on 19 January 2020

Impact of diabetes and smoking on mortality in tuberculosis

scientific article

Impaired Recognition of Mycobacterium tuberculosis by Alveolar Macrophages From Diabetic Mice

scientific article

Indicators for prediction of Mycobacterium tuberculosis positivity detected with bronchoalveolar lavage fluid.

scientific article

Initiation of acquired immunity in the lungs of mice lacking lymph nodes after infection with aerosolized Mycobacterium tuberculosis

scientific article

Interactions between Naïve and Infected Macrophages Reduce Mycobacterium tuberculosis Viability

scientific article published on November 18, 2011

Interferon-γ Regulates the Death of M. tuberculosis-Infected Macrophages.

scientific article published on March 2010

Interleukin-16 deficiency suppresses the development of chronic rejection in murine cardiac transplantation model

scientific article published on December 1, 2011

Interleukin-16 inhibits interleukin-13 production by allergen-stimulated blood mononuclear cells

scientific article published in January 2006

Intracellular bacillary burden reflects a burst size for Mycobacterium tuberculosis in vivo.

scientific article

Intrathymic programming of effector fates in three molecularly distinct γδ T cell subtypes

scientific article published on April 1, 2012

Is hypercholesterolemia a friend or a foe of tuberculosis?

scientific article published on August 2009

Lung Injury on Antiretroviral Therapy in Adults With Human Immunodeficiency Virus/Tuberculosis

scientific article published on 26 June 2019

Macrophage apoptosis in response to high intracellular burden of Mycobacterium tuberculosis is mediated by a novel caspase-independent pathway

scientific article published on 01 April 2006

Macrophage apoptosis in tuberculosis

scientific article published on 24 February 2009

Mannose-Capped Lipoarabinomannan from Mycobacterium tuberculosis Induces Soluble Tumor Necrosis Factor Receptor Production through Tumor Necrosis Factor Alpha-Converting Enzyme Activation.

scientific article published in February 2013

Mannose-Capped Lipoarabinomannan from Mycobacterium tuberculosis Preferentially Inhibits Sphingosine-1-Phosphate–Induced Migration of Th1 Cells

scientific article published on November 5, 2012

Mannose-capped Lipoarabinomannan from Mycobacterium tuberculosis induces soluble tumor necrosis factor receptor production through tumor necrosis factor alpha-converting enzyme activation

scientific article published on 27 August 2012

Meeting Report: NIH Workshop on the Tuberculosis Immune Epitope Database

scientific article published on 18 December 2007

Metformin enhances anti-mycobacterial responses by educating CD8+ T-cell immunometabolic circuits

scientific article published on 16 October 2020

Modulation of dendritic cell and monocyte subsets in tuberculosis-diabetes co-morbidity upon standard tuberculosis treatment

scientific article

Mycobacterium tuberculosis Induces an Atypical Cell Death Mode to Escape from Infected Macrophages

scientific article published on March 31, 2011

Mycobacterium tuberculosis blocks crosslinking of annexin-1 and apoptotic envelope formation on infected macrophages to maintain virulence

scientific article published on 14 September 2008

NK-CD11c+ Cell Crosstalk in Diabetes Enhances IL-6-Mediated Inflammation during Mycobacterium tuberculosis Infection

scientific article

Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome–dependent processing of IL-1β

scientific article published on November 18, 2012

Persistent inflammation during anti-tuberculosis treatment with diabetes comorbidity

scientific article published on 04 July 2019

Plasma Eicosanoid Levels in Tuberculosis and Tuberculosis-Diabetes Co-morbidity Are Associated With Lung Pathology and Bacterial Burden

scientific article published on 01 October 2019

Plasma chemokines are baseline predictors of unfavorable treatment outcomes in pulmonary tuberculosis

scientific article published on 07 August 2020

Plasma chemokines are biomarkers of disease severity, higher bacterial burden and delayed sputum culture conversion in pulmonary tuberculosis

scientific article published on 03 December 2019

Pro-IL-16 regulation in activated murine CD4+ lymphocytes

scientific article published on March 2005

Progress towards a genome-derived, epitope-driven vaccine for latent TB infection

scientific article published on October 2007

Pulmonary restriction predicts long-term pulmonary impairment in people with HIV and tuberculosis

scientific article published on 07 January 2021

Reduced prevalence of latent tuberculosis infection in diabetes patients using metformin and statins

scientific article published on 14 March 2019

Regulation of nuclear Prointerleukin-16 and p27(Kip1) in primary human T lymphocytes

scientific article published on September 2005

Systemic RAGE ligands are upregulated in tuberculosis individuals with diabetes co-morbidity and modulated by anti-tuberculosis treatment and metformin therapy

scientific article published on 09 December 2019

Systems Immunology of Diabetes-Tuberculosis Comorbidity Reveals Signatures of Disease Complications

scientific article

THP-1 cell apoptosis in response to Mycobacterial infection

scientific article

Tuberculosis Susceptibility and Vaccine Protection Are Independently Controlled by Host Genotype

scientific article published on 20 September 2016

Tuberculosis and lung damage: from epidemiology to pathophysiology

scientific article

Tuberculosis susceptibility of diabetic mice

scientific article

Tuberculosis-diabetes co-morbidity is characterized by heightened systemic levels of circulating angiogenic factors

scientific article

mTORC2/Akt activation in adipocytes is required for adipose tissue inflammation in tuberculosis

scientific article published on 04 July 2019