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List of works by Yechun Xu

Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design

scientific article published on 09 August 2019

Diterpenoids from the Root Bark of Pinus massoniana and Evaluation of Their Phosphodiesterase Type 4D Inhibitory Activity

scientific article published on 26 February 2020

Exploration of Fragment Binding Poses Leading to Efficient Discovery of Highly Potent and Orally Effective Inhibitors of FABP4 for Anti-inflammation

scientific article published on 10 April 2020

Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease

scientific article published on 15 June 2021

Pharmacokinetics-Driven Optimization of 4(3 H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension

scientific article published on 08 May 2019

Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5

scientific article published on 06 July 2021

Structural basis of ligand binding modes at the human formyl peptide receptor 2

scientific article published on 05 March 2020

Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent

scientific article published on 31 May 2019

Structure-Based Survey of the Binding Modes of BACE1 Inhibitors

scientific article published on 27 December 2018

Structure-Guided Discovery of Novel, Potent, and Orally Bioavailable Inhibitors of Lipoprotein-Associated Phospholipase A2.

scientific article

Structure-based design of a novel inhibitor of the ZIKA virus NS2B/NS3 protease

scientific article published in 2022

The Molecular Mechanism Underlying Ligand Binding to the Membrane-Embedded Site of a G-Protein-Coupled Receptor

scientific article published on 27 April 2018

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