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List of works by Livio Trusolino

A Molecularly Annotated Model of Patient-Derived Colon Cancer Stem-Like Cells to Assess Genetic and Nongenetic Mechanisms of Resistance to Anti-EGFR Therapy.

scientific article published on 3 October 2017

A diphtheria toxin resistance marker for in vitro and in vivo selection of stably transduced human cells

scientific article

A module of inflammatory cytokines defines resistance of colorectal cancer to EGFR inhibitors.

scientific article published on 30 September 2016

Adaptive mutability of colorectal cancers in response to targeted therapies

scientific article published on 07 November 2019

Altered expression of α6 integrin subunit in oral squamous cell carcinoma and oral potentially malignant lesions ⬇️

scientific article published on May 1, 1998

Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer

scientific article

An 'in-cell trial' to assess the efficacy of a monovalent anti-MET antibody as monotherapy and in association with standard cytotoxics

scientific article published on 18 December 2013

Anti-cancer effect and gene modulation of ET-743 in human biliary tract carcinoma preclinical models

scientific article

Colorectal cancer residual disease at maximal response to EGFR blockade displays a druggable Paneth cell-like phenotype

scientific article published on 01 August 2020

Combined blockade of MEK and PI3KCA as an effective antitumor strategy in HER2 gene amplified human colorectal cancer models

scientific article published on 04 June 2019

Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

scientific article published on 07 January 2021

Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-label, phase 2 trial

scientific article

Efficacy of NEDD8 Pathway Inhibition in Preclinical Models of Poorly Differentiated, Clinically Aggressive Colorectal Cancer

scientific article

Evolving neoantigen profiles in colorectal cancers with DNA repair defects

scientific article published on 28 June 2019

Growth Factor–dependent Activation of αvβ3 Integrin in Normal Epithelial Cells: Implications for Tumor Invasion ⬇️

scientific article published on August 24, 1998

HER2 Positivity Predicts Unresponsiveness to EGFR-Targeted Treatment in Metastatic Colorectal Cancer

scientific article published on 05 April 2019

INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases

scientific article published on 12 April 2019

INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases

scientific article published on 24 May 2019

Immunogenomics of Colorectal Tumors: Facts and Hypotheses on an Evolving Saga

scientific article published on 06 November 2019

Inhibition of poly(ADP-ribosyl)ation in cancer: old and new paradigms revisited

scientific article published on 12 July 2014

Interrogating open issues in cancer precision medicine with patient-derived xenografts.

scientific article published on 20 January 2017

Intratumoral Transcriptome Heterogeneity Is Associated With Patient Prognosis and Sidedness in Patients With Colorectal Cancer Treated With Anti-EGFR Therapy From the CO.20 Trial

scientific article published on 29 September 2020

Known and novel roles of the MET oncogene in cancer: a coherent approach to targeted therapy.

scientific article published on 19 April 2018

Lenalidomide normalizes tumor vessels in colorectal cancer improving chemotherapy activity

scientific article published on 5 May 2016

Oncogene addiction as a foundational rationale for targeted anti‐cancer therapy: promises and perils ⬇️

scientific article published on September 23, 2011

Oncogenic MET as an Effective Therapeutic Target in Non-Small Cell Lung Cancer Resistant to EGFR Inhibitors: The Rise of the Phoenix.

scientific article published in December 2016

Patient-Derived Xenografts and Matched Cell Lines Identify Pharmacogenomic Vulnerabilities in Colorectal Cancer

scientific article published on 02 August 2019

Plasma HER2 (ERBB2) Copy Number Predicts Response to HER2-targeted Therapy in Metastatic Colorectal Cancer

scientific article published on 26 February 2019

Primary and acquired resistance to EGFR-targeted therapies in colorectal cancer: impact on future treatment strategies

scientific article

Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens

scientific article published on 10 April 2019

RET fusions in a small subset of advanced colorectal cancers at risk of being neglected

scientific article published on 10 March 2018

Radiologic and Genomic Evolution of Individual Metastases during HER2 Blockade in Colorectal Cancer

scientific article published on 01 July 2018

Rebound Effects Caused by Withdrawal of MET Kinase Inhibitor Are Quenched by a MET Therapeutic Antibody

scientific article published on 30 June 2016

Selective analysis of cancer-cell intrinsic transcriptional traits defines novel clinically relevant subtypes of colorectal cancer

scientific article published on 31 May 2017

Targeting the MET gene for the treatment of non-small-cell lung cancer

scientific article published on December 2013

Targeting the human epidermal growth factor receptor 2 (HER2) oncogene in colorectal cancer.

scientific article

The ROR1 pseudokinase diversifies signaling outputs in MET-addicted cancer cells.

scientific article published on 15 April 2014

The Stromal and Immune Landscape of Colorectal Cancer Progression during Anti-EGFR Therapy

scientific article published on 01 July 2019

The genomic landscape of response to EGFR blockade in colorectal cancer.

scientific article published on 30 September 2015

Topography and biological role of integrins in human skin ⬇️

scientific article published on August 15, 1997

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