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List of works by Francisco J. Quintana

A gut feeling about multiple sclerosis

scientific article published on 25 September 2017

A potential role for AHR in SARS-CoV-2 pathology

scientific article published on 27 April 2020

A structurally altered D,L-amino acid TCRalpha transmembrane peptide interacts with the TCRalpha and inhibits T-cell activation in vitro and in an animal model

scientific article published on 9 February 2007

A systems immunology approach to the host-tumor interaction: large-scale patterns of natural autoantibodies distinguish healthy and tumor-bearing mice.

scientific article

AHR Activation Is Protective against Colitis Driven by T Cells in Humanized Mice

scientific article published on October 2016

AHR is a Zika virus host factor and a candidate target for antiviral therapy

scientific article published on 20 July 2020

AHR signaling is induced by infection with coronaviruses

scientific article published on 26 August 2021

Achieving Tolerance with Perforin-Secreting Dendritic Cells

scientific article

Activated Human CD4+CD45RO+ Memory T-Cells Indirectly Inhibit NLRP3 Inflammasome Activation through Downregulation of P2X7R Signalling

scientific article published on June 29, 2012

Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell-like and Foxp3(+) regulatory T cells

scientific article

Activin-A limits Th17 pathogenicity and autoimmune neuroinflammation via CD39 and CD73 ectonucleotidases and Hif1-α-dependent pathways

scientific article published on 14 May 2020

Adaptive autoimmunity and Foxp3-based immunoregulation in zebrafish

scientific article

Aiolos promotes TH17 differentiation by directly silencing Il2 expression

scientific article published on July 1, 2012

Alterations of the human gut microbiome in multiple sclerosis.

scientific article published on 28 June 2016

An endogenous aryl hydrocarbon receptor ligand acts on dendritic cells and T cells to suppress experimental autoimmune encephalomyelitis

scientific article published on November 10, 2010

Analyses of antigen dependency networks unveil immune system reorganization between birth and adulthood

scientific article published on March 1, 2011

Angiogenesis-inflammation cross-talk: vascular endothelial growth factor is secreted by activated T cells and induces Th1 polarization

scientific journal article

Anti-ergotypic T cells in naïve rats

scientific article published on 01 May 2005

Anti-inflammatory effects of melatonin in multiple sclerosis

scientific article

Antigen Microarrays for the Study of Autoimmune Diseases

scientific article published on March 13, 2013

Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis

scientific article

Aryl Hydrocarbon Receptor Activation in Astrocytes by Laquinimod Ameliorates Autoimmune Inflammation in the CNS

scientific article published on 06 January 2021

Aryl Hydrocarbon Receptor Plasma Agonist Activity Correlates With Disease Activity in Progressive MS

scientific article published on 24 December 2020

Aryl hydrocarbon receptor control of adaptive immunity

scientific article

Astrocyte Crosstalk in CNS Inflammation

scientific article published on 30 August 2020

Astrocytes play a crucial role in the formation and evolution of MS lesions - Commentary

scientific article published on 23 August 2018

Astrocytes to the rescue! Glia limitans astrocytic endfeet control CNS inflammation

scientific article

Author Correction: AHR is a Zika virus host factor and a candidate target for antiviral therapy

scientific article published on 10 August 2020

Author Correction: Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39

scientific article published on 01 September 2019

Autoimmune encephalomyelitis and uveitis induced by T cell immunity to self beta-synuclein

scientific article published on January 2003

Barcoded viral tracing of single-cell interactions in central nervous system inflammation

scientific article

Bilirubin suppresses Th17 immunity in colitis by upregulating CD39.

scientific article published on 4 May 2017

Binding Mode and Structure-Activity Relationships of ITE as an Aryl Hydrocarbon Receptor (AhR) Agonist.

scientific article published on 20 December 2017

Characterization of human CD39+ Th17 cells with suppressor activity and modulation in inflammatory bowel disease

scientific article

Checkpoint Receptor TIGIT Expressed on Tim-1+ B Cells Regulates Tissue Inflammation

scientific article published on 01 July 2020

Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation

scientific article published in Nature Communications

Circulating microRNAs as biomarkers for disease staging in multiple sclerosis

scientific article

Cluster analysis of human autoantibody reactivities in health and in type 1 diabetes mellitus: a bio-informatic approach to immune complexity

scientific article published in August 2003

Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor

scientific article

Control of autoimmune CNS inflammation by astrocytes

scientific article

Control of immune-mediated pathology via the aryl hydrocarbon receptor

scientific article

Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39

scientific article published on 08 April 2019

Cutting edge: human latency-associated peptide+ T cells: a novel regulatory T cell subset

scientific article

D-enantiomer peptide of the TCRalpha transmembrane domain inhibits T-cell activation in vitro and in vivo

scientific article

DNA Fragments of the Human 60-kDa Heat Shock Protein (HSP60) Vaccinate Against Adjuvant Arthritis: Identification of a Regulatory HSP60 Peptide

scientific article published on 01 October 2003

DNA Vaccination with Heat Shock Protein 70 Protects (NZB x NZW)F1 Mice from Systemic Lupus Erythematosus

scientific article published on 13 January 2020

DNA vaccination with CD25 protects rats from adjuvant arthritis and induces an antiergotypic response

scientific article published on March 2004

DNA vaccination with heat shock protein 60 inhibits cyclophosphamide-accelerated diabetes

scientific article published on November 2002

DNA vaccine encoding heat shock protein 90 protects from murine lupus

scientific article published on 22 June 2020

DNA vaccines coding for heat-shock proteins (HSPs): tools for the activation of HSP-specific regulatory T cells

scientific article

Defect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant mice.

scientific article

Dendritic cells in autoimmunity, infections, and cancer.

scientific article published on 16 January 2017

Detection of aryl hydrocarbon receptor agonists in human samples.

scientific article published on 21 March 2018

Digestion of Chromatin in Apoptotic Cell Microparticles Prevents Autoimmunity

scientific article published on 09 June 2016

Dynamic regulation of serum aryl hydrocarbon receptor agonists in MS

scientific article

Ectopic PDX-1 expression in liver ameliorates type 1 diabetes

scientific article published on 23 March 2007

Editorial: Update on Translational Neuroimmunology - Research of ISNI 2018

scientific article published on 30 September 2020

Effects of Systolic Blood Pressure on Brain Integrity in Multiple Sclerosis.

scientific article published on 25 June 2018

Environmental Control of Astrocyte Pathogenic Activities in CNS Inflammation

scientific article published on 17 January 2019

Environmental control of Th17 differentiation

scientific article published on March 2009

Environmental control of autoimmune inflammation in the central nervous system

scientific article

Epigenetic control of early neurodegenerative events in diabetic retinopathy by the histone deacetylase SIRT6.

scientific article

Epitope spreading as an early pathogenic event in pediatric multiple sclerosis

scientific article

Evaluation of circulating osteopontin levels in an unselected cohort of patients with multiple sclerosis: relevance for biomarker development

scientific article published on 4 September 2013

Examining effects of anticipated stigma, centrality, salience, internalization, and outness on psychological distress for people with concealable stigmatized identities

scientific article

Experimental autoimmune myasthenia gravis in naive non-obese diabetic (NOD/LtJ) mice: susceptibility associated with natural IgG antibodies to the acetylcholine receptor

scientific article

Fatal autoimmunity in mice reconstituted with human hematopoietic stem cells encoding defective FOXP3

scientific article published on April 2015

From initial segment to cauda: A regional characterization of mouse epididymal CD11c+ mononuclear phagocytes based on immune phenotype and function

scientific article published on 29 September 2020

Functional immunomics: microarray analysis of IgG autoantibody repertoires predicts the future response of mice to induced diabetes.

scholarly article

Glial Cells as Regulators of Neuroimmune Interactions in the Central Nervous System

scientific article published on 01 January 2020

Gut-licensed IFNγ NK cells drive LAMP1TRAIL anti-inflammatory astrocytes

scientific article

Gut-tropic T cells that express integrin α4β7 and CCR9 are required for induction of oral immune tolerance in mice

scientific article published on 16 September 2011

HIF-1α-induced xenobiotic transporters promote Th17 responses in Crohn's disease

article

HIV-1 fusion peptide targets the TCR and inhibits antigen-specific T cell activation

scientific article

HSP60 as a target of anti-ergotypic regulatory T cells

scientific journal article

HSP60 speaks to the immune system in many voices

scientific article published on 01 January 2008

Heat shock proteins as endogenous adjuvants in sterile and septic inflammation

scientific article

IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment

scientific article

IL-10-dependent Tr1 cells attenuate astrocyte activation and ameliorate chronic central nervous system inflammation

scientific article published on 31 May 2016

IL-21 induces IL-22 production in CD4+ T cells.

scientific article

IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39.

scientific article published on September 2013

IMMU-54. THE ONCOMETABOLITE R-2-HYDROXYGLUTARATE SUPPRESSES THE INNATE IMMUNE MICROENVIRONMENT OF IDH1-MUTATED GLIOMAS VIA ARYL HYDROCARBON RECEPTOR SIGNALING

Imaging-AMARETTO: An Imaging Genomics Software Tool to Interrogate Multiomics Networks for Relevance to Radiography and Histopathology Imaging Biomarkers of Clinical Outcomes

scientific article published on 01 May 2020

Immunological Relevance of the Coevolution of IDO1 and AHR

scientific article

In vivo induction of Tr1 cells via mucosal dendritic cells and AHR signaling

scientific article

Individual and meta-immune networks.

scientific article published on 15 March 2013

Induction and molecular signature of pathogenic TH17 cells

scientific article

Induction of IgG3 to LPS via Toll-like receptor 4 co-stimulation

scientific article

Inhibition of adjuvant arthritis by a DNA vaccine encoding human heat shock protein 60

scientific article published on 01 September 2002

Inhibition of adjuvant-induced arthritis by DNA vaccination with the 70-kd or the 90-kd human heat-shock protein: immune cross-regulation with the 60-kd heat-shock protein

scientific article published on 01 November 2004

Interleukin 1β Mediates Intestinal Inflammation in Mice and Patients With Interleukin 10 Receptor Deficiency.

scientific article published on 27 September 2016

Interleukin-10 receptor signaling in innate immune cells regulates mucosal immune tolerance and anti-inflammatory macrophage function

scientific article published in May 2014

Knock-out of the histidine decarboxylase gene modifies the repertoire of natural autoantibodies.

scientific article published in June 2004

LeA(H)Rning self-control

scientific article published on 25 July 2014

Leptin deficiency impairs maturation of dendritic cells and enhances induction of regulatory T and Th17 cells

scientific article published on 13 January 2014

Lipids and lipid-reactive antibodies as biomarkers for multiple sclerosis

scientific article published on May 12, 2012

MAFG-driven astrocytes promote CNS inflammation

scientific article published on 12 February 2020

MRI phenotypes in MS: Longitudinal changes and miRNA signatures

Melatonin Contributes to the Seasonality of Multiple Sclerosis Relapses

scientific article

Meningeal Memories of Viral Infection

scientific article published on 25 June 2019

Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS

scientific article published on 05 December 2019

Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-α.

scientific article published on 25 May 2015

Microglial control of astrocytes in response to microbial metabolites.

scientific article

Mucosal administration of CD3-specific monoclonal antibody inhibits diabetes in NOD mice and in a preclinical mouse model transgenic for the CD3 epsilon chain

scientific article published on 10 October 2016

Myeloid cells in the central nervous system: So similar, yet so different

scientific article published on 08 February 2019

NAP, a peptide derived from the activity-dependent neuroprotective protein, modulates macrophage function

scientific article published on July 2006

Nanoparticle-mediated codelivery of myelin antigen and a tolerogenic small molecule suppresses experimental autoimmune encephalomyelitis

scientific article

Nanoparticles for the Induction of Antigen-Specific Tregs

scientific article published on May 1, 2013

Nasal anti-CD3 antibody ameliorates lupus by inducing an IL-10-secreting CD4+ CD25- LAP+ regulatory T cell and is associated with down-regulation of IL-17+ CD4+ ICOS+ CXCR5+ follicular helper T cells

scientific article

Negative feedback control of neuronal activity by microglia

scientific article published on 30 September 2020

Network theory analysis of antibody-antigen reactivity data: the immune trees at birth and adulthood

scientific article

Newborn humans manifest autoantibodies to defined self molecules detected by antigen microarray informatics

scientific article published on March 2007

Norepinephrine Controls Effector T Cell Differentiation through β2-Adrenergic Receptor-Mediated Inhibition of NF-κB and AP-1 in Dendritic Cells

scientific article published on 11 December 2015

Old dog, new tricks: IL-6 cluster signaling promotes pathogenic TH17 cell differentiation

scientific article published in December 2016

Oral administration of OKT3 monoclonal antibody to human subjects induces a dose-dependent immunologic effect in T cells and dendritic cells

scientific article published on 16 September 2009

Oral tolerance

scientific article published on 01 May 2011

Organization of the autoantibody repertoire in healthy newborns and adults revealed by system level informatics of antigen microarray data.

scientific article

Overexpression of the Ctla-4 isoform lacking exons 2 and 3 causes autoimmunity

scientific article published on 28 November 2011

Peptide p277 of HSP60 signals T cells: inhibition of inflammatory chemotaxis

scientific article published on 07 August 2006

Placental immunomodulator ferritin, a novel immunoregulator, suppresses experimental arthritis

scientific article published on 01 March 2003

Precision Medicine in Multiple Sclerosis: Future of PET Imaging of Inflammation and Reactive Astrocytes

scientific article

Protocol for <i>in vitro</i> analysis of pro-inflammatory and metabolic functions of cultured primary murine astrocytes

scientific article published on 15 December 2021

Protocol for inducing inflammation and acute myelin degeneration in larval zebrafish

scientific article published on 28 January 2022

Purinergic Signaling as a Regulator of Th17 Cell Plasticity

scientific article

Reactive astrocyte nomenclature, definitions, and future directions

journal article published in 2021

Regulation of Astrocyte Functions in Multiple Sclerosis

scientific article published on 22 January 2018

Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation.

scientific article

Regulation of central nervous system autoimmunity by the aryl hydrocarbon receptor

scientific article published on 03 September 2013

Regulation of the Immune Response by the Aryl Hydrocarbon Receptor

scientific article published in January 2018

Regulation of the T Cell Response by CD39.

scientific article published on 25 May 2016

Regulatory T cells and immune computation

scientific article published in April 2008

Response to "Interaction between HIV gp41 fusion peptide and T cell receptor: putting the puzzle pieces back together".

scientific article published in June 2007

Reversal of axonal loss and disability in a mouse model of progressive multiple sclerosis.

scientific article

Role of AHR and HIF-1α in Glioblastoma Metabolism

scientific article published on 16 March 2017

Role of AHR in the control of GBM-associated myeloid cells

scientific article published on 23 May 2019

Role of Aryl Hydrocarbon Receptor (AhR) in the Regulation of Immunity and Immunopathology During Infection

Role of Sphingolipid Metabolism in Neurodegeneration

scientific article published on 13 May 2020

Role of astrocytes and microglia in central nervous system inflammation. Introduction

scientific article published on 13 August 2015

SARS-CoV-2-induced lung pathology: AHR as a candidate therapeutic target

scientific article published on 01 December 2020

Sample size requirements for one-year treatment effects using deep gray matter volume from 3T MRI in progressive forms of multiple sclerosis

scientific article published on 19 January 2017

Say "adios" to the American dream? The interplay between ethnic and national identity among Latino and Caucasian Americans

scientific article

Science Signaling Podcast for 21 June 2016: Nanoparticles to treat type 1 diabetes

scientific article published on 21 June 2016

Serum antibodies to phosphatidylcholine in MS

scientific article published on 09 June 2020

Serum lipid antibodies are associated with cerebral tissue damage in multiple sclerosis

scientific article published on 27 January 2016

Sodium intake is associated with increased disease activity in multiple sclerosis

scientific article published on 28 August 2014

Sphingosine 1-phosphate receptor modulation suppresses pathogenic astrocyte activation and chronic progressive CNS inflammation.

scientific article published on 6 February 2017

Synthetic biology: at the crossroads of genetic engineering and human therapeutics—a Keystone Symposia report

scientific article published in 2021

System-wide Analysis of the T Cell Response

scientific article published on 8 March 2016

Systems biology approaches for the study of multiple sclerosis

scientific article published on 26 May 2008

T Follicular Regulatory Cell-Derived Fibrinogen-like Protein 2 Regulates Production of Autoantibodies and Induction of Systemic Autoimmunity

scientific article published on 09 November 2020

T and B cell hyperactivity and autoimmunity associated with niche-specific defects in apoptotic body clearance in TIM-4-deficient mice

scientific article

T-cell inactivation and immunosuppressive activity induced by HIV gp41 via novel interacting motif

scientific article

Targeted Single-Cell RNA and DNA Sequencing With Fluorescence-Activated Droplet Merger

scientific article published on 13 October 2020

The 'Omics' of Amyotrophic Lateral Sclerosis.

scientific article published on 12 December 2015

The Gut-CNS Axis in Multiple Sclerosis

scientific article published on 07 July 2020

The HSP60 immune system network

scientific article published on 08 December 2010

The Role of Astrocytes in CNS Inflammation

scientific article published on 13 August 2020

The Sympathetic Nervous System Mitigates CNS Autoimmunity via β2-Adrenergic Receptor Signaling in Immune Cells

scientific article published on 01 September 2019

The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27.

scientific article

The aryl hydrocarbon receptor: a molecular pathway for the environmental control of the immune response

scientific article

The aryl hydrocarbon receptor: an environmental sensor integrating immune responses in health and disease

scientific article published on 01 March 2019

The innate immune system in demyelinating disease

scientific article published on July 1, 2012

The natural autoantibody repertoire and autoimmune disease

scientific article published on June 2004

Tim-3/galectin-9 pathway: regulation of Th1 immunity through promotion of CD11b+Ly-6G+ myeloid cells.

scientific article

Tolerogenic dendritic cells.

scientific article published on 19 September 2016

Tolerogenic nanoparticles inhibit T cell-mediated autoimmunity through SOCS2.

scientific article published on 21 June 2016

Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE.

scientific article published on 16 August 2009

Toll-like receptor stimulation differentially regulates vasoactive intestinal peptide type 2 receptor in macrophages

scientific article published in September 2009

Toll-like receptor stimulation differentially regulates vasoactive intestinal peptide type 2 receptor in macrophages

Treg cells expressing the coinhibitory molecule TIGIT selectively inhibit proinflammatory Th1 and Th17 cell responses

scientific article

Tregs in T cell vaccination: exploring the regulation of regulation

scientific article

Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor

scientific article published on 09 May 2016

Understanding natural and pathological autoimmunity

scientific article published on 13 March 2006

[Immunopathology of multiple sclerosis]

scientific article published on 01 January 2014