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List of works by Patrick F Smith

A phase I trial of PRN1008, a novel reversible covalent inhibitor of Bruton's tyrosine kinase, in healthy volunteers.

scientific article published on 21 June 2017

Antiviral Activity of Danoprevir (ITMN-191/RG7227) in Combination With Pegylated Interferon α-2a and Ribavirin in Patients With Hepatitis C ⬇️

scientific article published on August 15, 2011

Characterization of Hepatitis C Virus (HCV) Quasispecies Dynamics upon Short-Term Dual Therapy with the HCV NS5B Nucleoside Polymerase Inhibitor Mericitabine and the NS3/4 Protease Inhibitor Danoprevir ⬇️

scientific article published on August 6, 2012

Clinical Pharmacology Knowledge, Opportunities and Working Strengths (CPKNOWS): a competency model for pursuit of excellence in clinical pharmacology ⬇️

scientific article published on December 1, 2013

Danoprevir Monotherapy Decreases Inflammatory Markers in Patients with Chronic Hepatitis C Virus Infection ⬇️

scientific article published on April 18, 2011

Dosing will be a key success factor in repurposing antivirals for COVID-19

scientific article published on 17 April 2020

New Modified Fluorescence Polarization Immunoassay Does Not Falsely Elevate Vancomycin Concentrations in Patients With End-Stage Renal Disease ⬇️

scientific article published on 01 April 1998

Oral combination therapy with a nucleoside polymerase inhibitor (RG7128) and danoprevir for chronic hepatitis C genotype 1 infection (INFORM-1): a randomised, double-blind, placebo-controlled, dose-escalation trial ⬇️

scientific article published on October 14, 2010

Pharmacokinetic/Pharmacodynamic Predictors of Clinical Potency for Hepatitis C Virus Nonnucleoside Polymerase and Protease Inhibitors ⬇️

scientific article published on April 2, 2012

Pharmacologic effects of oseltamivir in immunocompromised adult patients as assessed by population PK/PD analysis and drug-disease modeling for dosing regimen optimization

scientific article published on 17 August 2020

Physiological modeling and assessments of regional drug bioavailability of danoprevir to determine whether a controlled release formulation is feasible ⬇️

scientific article published on June 9, 2011

Safety, efficacy and pharmacokinetics of linezolid for treatment of resistant Gram-positive infections in cancer patients with neutropenia ⬇️

scientific article published on May 1, 2003

Using in silico viral kinetic models to guide therapeutic strategies during a pandemic: An example in SARS-CoV-2

scientific article published on 29 December 2020

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