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List of works by Thomas Blank

A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease.

scientific article published on 30 August 2017

Altered microglia morphology and higher resilience to stress-induced depression-like behavior in CX3CR1-deficient mice

scientific article published on 11 November 2015

Brain Endothelial- and Epithelial-Specific Interferon Receptor Chain 1 Drives Virus-Induced Sickness Behavior and Cognitive Impairment

scientific article published on April 2016

CatacLysMic specificity when targeting myeloid cells?

scientific article published on 19 May 2016

Deep Spatial Profiling of COVID-19 Brains Reveals Neuroinflammation by Compartmentalized Local Immune Cell Interactions and Targets for Intervention

scientific article published in 2021

Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions

scientific article published on 9 June 2021

Dendritic Cells Ameliorate Autoimmunity in the CNS by Controlling the Homeostasis of PD-1 Receptor+ Regulatory T Cells

scientific article published on 16 August 2012

Dicer Deficiency Differentially Impacts Microglia of the Developing and Adult Brain

scientific article published in June 2017

Different effects of constitutive and induced microbiota modulation on microglia in a mouse model of Alzheimer's disease

scientific article published on 29 July 2020

Early Microglia Activation Precedes Photoreceptor Degeneration in a Mouse Model of CNGB1-Linked Retinitis Pigmentosa

scientific article published in January 2017

Fine-tuning of type I IFN-signaling in microglia--implications for homeostasis, CNS autoimmunity and interferonopathies

scientific article published on 19 September 2015

Genetic Cell Ablation Reveals Clusters of Local Self-Renewing Microglia in the Mammalian Central Nervous System

scientific article published on 7 July 2015

Graft-versus-host disease of the CNS is mediated by TNF upregulation in microglia

scientific article published on 01 March 2020

Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner.

scientific article published on 7 March 2018

IkappaB kinase 2 determines oligodendrocyte loss by non-cell-autonomous activation of NF-kappaB in the central nervous system

scientific article

Inhibition of experimental autoimmune encephalomyelitis by tolerance-promoting DNA vaccination focused to dendritic cells.

scientific article

Innate immune memory in the brain shapes neurological disease hallmarks

scientific article published in Nature

Loss of USP18 in microglia induces white matter pathology

scientific article published on 04 July 2019

Microglia as modulators of cognition and neuropsychiatric disorders

scientific article published on 27 June 2012

Microglia fuel the learning brain

scientific article published on 11 March 2014

Microglial CX3CR1 promotes adult neurogenesis by inhibiting Sirt 1/p65 signaling independent of CX3CL1

scientific article published on 17 September 2016

NF-κB signaling regulates myelination in the CNS.

scientific article

Neonatal immune challenge poses a sex-specific risk for epigenetic microglial reprogramming and behavioral impairment

Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature

scientific article published on 15 June 2020

Profiling peripheral nerve macrophages reveals two macrophage subsets with distinct localization, transcriptome and response to injury

scientific article published on 13 April 2020

Seed-induced Aβ deposition is modulated by microglia under environmental enrichment in a mouse model of Alzheimer's disease.

scientific article

Silencing of TGFβ signalling in microglia results in impaired homeostasis

scientific article published in Nature Communications

Type I interferon pathway in CNS homeostasis and neurological disorders.

scientific article

USP18 lack in microglia causes destructive interferonopathy of the mouse brain

scientific article published on 20 April 2015