List of works - Shelly J. Krebs

641Acute Retroviral Syndrome is Associated with Gut Mucosal CD4 Depletion, Inflammation and High Viral and Proviral Burden in Systemic and Tissue Compartments.

scientific article published in December 2014

A high-throughput multiplex assay to characterize flavivirus-specific immunoglobulins

scientific article published on 03 October 2020

A recombinant gp145 Env glycoprotein from HIV-1 expressed in two different cell lines: Effects on glycosylation and antigenicity

scientific article published on 19 June 2020

Achieving Potent Autologous Neutralizing Antibody Responses against Tier 2 HIV-1 Viruses by Strategic Selection of Envelope Immunogens

scientific article published on 4 March 2016

Activated PD-1+ CD4+ T cells represent a short-lived part of the viral reservoir and predict poor immunologic recovery upon initiation of ART

scientific article published on 01 February 2020

Acute Retroviral Syndrome is Associated with High Viral Burden, CD4 Depletion, and Immune Activation in Systemic and Tissue Compartments

scientific article published on 7 December 2017

Central nervous system safety during brief analytic treatment interruption of antiretroviral therapy within four HIV remission trials: an observational study in acutely treated people living with HIV

scientific article published on 11 September 2020

Characterization of a novel protective monoclonal antibody that recognizes an epitope common to Vibrio cholerae Ogawa and Inaba serotypes

scientific article

Co-immunization with multimeric scaffolds and DNA rapidly induces potent autologous HIV-1 neutralizing antibodies and CD8+ T cells

scientific article (publication date: 2012)

Comparable Antigenicity and Immunogenicity of Oligomeric Forms of a Novel, Acute HIV-1 Subtype C gp145 Envelope for Use in Preclinical and Clinical Vaccine Research

scientific article published on 13 May 2015

Correction: Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection

scientific article published on 14 September 2017

Crystal Structure of the Vibrio cholerae Colonization Factor TcpF and Identification of a Functional Immunogenic Site

scientific article

Delivery strategies for novel vaccine formulations

scientific article published on February 2012

Distinct biomarker signatures in HIV acute infection associate with viral dynamics and reservoir size

scientific article

Distribution of HIV RNA in CSF and Blood is linked to CD4/CD8 Ratio During Acute HIV.

scientific article

Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection

scientific article published on 14 January 2020

E2 multimeric scaffold for vaccine formulation: immune response by intranasal delivery and transcriptome profile of E2-pulsed dendritic cells

scientific article

Envelope variants circulating as initial neutralization breadth developed in two HIV-infected subjects stimulate multiclade neutralizing antibodies in rabbits.

scientific article

Expansion of Inefficient HIV-Specific CD8 T Cells during Acute Infection

scientific article published on 3 February 2016

Fine epitope signature of antibody neutralization breadth at the HIV-1 envelope CD4-binding site

scientific article published on 8 March 2018

Genetic mapping of secretion and functional determinants of the Vibrio cholerae TcpF colonization factor

scientific article published on 20 March 2009

HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies

scientific article published on 01 April 2020

HLA class II genes modulate vaccine-induced antibody responses to affect HIV-1 acquisition

scientific article published on July 2015

High Number of Activated CD8+ T Cells Targeting HIV Antigens Are Present in Cerebrospinal Fluid in Acute HIV Infection

scientific article published on 07 February 2017

Immediate initiation of cART is associated with lower levels of cerebrospinal fluid YKL-40, a marker of microglial activation, in HIV-1 infection.

scientific article published on 2 November 2016

Immune activation during acute HIV infection and the impact of early antiretroviral therapy

scientific article

Improvement of antibody responses by HIV envelope DNA and protein co-immunization.

scientific article

Initiation of antiretroviral therapy before detection of colonic infiltration by HIV reduces viral reservoirs, inflammation and immune activation

scientific article published on 15 September 2016

Limited Evidence for a Relationship between HIV-1 Glycan Shield Features in Early Infection and the Development of Neutralization Breadth

scientific article published on 10 August 2021

Liver function test abnormalities in a longitudinal cohort of Thai individuals treated since acute HIV infection

scientific article published on 01 January 2020

Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual

scientific article published on 12 March 2019

Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations

scientific article published on 29 October 2021

Monocyte and CD4+ T cell antiviral and innate responses associated with HIV-1 inflammation and cognitive impairment

scientific article published on 13 April 2020

Multimeric Epitope-Scaffold HIV Vaccines Target V1V2 and Differentially Tune Polyfunctional Antibody Responses

scientific article published on 01 July 2019

Multimeric scaffolds displaying the HIV-1 envelope MPER induce MPER-specific antibodies and cross-neutralizing antibodies when co-immunized with gp160 DNA

scientific article

Neurologic signs and symptoms frequently manifest in acute HIV infection

scientific article published on 10 June 2016

Normalization of Soluble CD163 Levels After Institution of Antiretroviral Therapy During Acute HIV Infection Tracks with Fewer Neurological Abnormalities

article

Nutrient-dependent, rapid transition of Vibrio cholerae to coccoid morphology and expression of the toxin co-regulated pilus in this form

scientific article

Persistent, Albeit Reduced, Chronic Inflammation in Persons Starting Antiretroviral Therapy in Acute HIV Infection

scientific article

Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor

scientific article published on 03 February 2020

Protection and attachment of Vibrio cholerae mediated by the toxin-coregulated pilus in the infant mouse model

scientific article published on 29 July 2011

RV144 HIV-1 vaccination impacts post-infection antibody responses

scientific article published on 08 December 2020

Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection

scientific article published on 31 July 2017

SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity

scientific article published on 08 December 2021

Safety and efficacy of VRC01 broadly neutralising antibodies in adults with acutely treated HIV (RV397): a phase 2, randomised, double-blind, placebo-controlled trial

scientific article published on 15 April 2019

Safety and immunogenicity of a purified inactivated Zika virus vaccine candidate in adults primed with a Japanese encephalitis virus or yellow fever virus vaccine in the USA: a phase 1, randomised, double-blind, placebo-controlled clinical trial

scientific article published in 2023

Sex differences in soluble markers vary before and after the initiation of antiretroviral therapy in chronically HIV-infected individuals

scientific article published on 16 March 2016

Vaccine delivery to the oral cavity using coated microneedles induces systemic and mucosal immunity

scientific article

Very Early Initiation of Antiretroviral Therapy During Acute HIV Infection Is Associated With Normalized Levels of Immune Activation Markers in Cerebrospinal Fluid but Not in Plasma

scientific article published on 01 November 2019

Virological and immunological characteristics of HIV-infected individuals at the earliest stage of infection

scientific article published on January 2016

List of works by Shelly J. Krebs

641Acute Retroviral Syndrome is Associated with Gut Mucosal CD4 Depletion, Inflammation and High Viral and Proviral Burden in Systemic and Tissue Compartments.

A high-throughput multiplex assay to characterize flavivirus-specific immunoglobulins

A recombinant gp145 Env glycoprotein from HIV-1 expressed in two different cell lines: Effects on glycosylation and antigenicity

Achieving Potent Autologous Neutralizing Antibody Responses against Tier 2 HIV-1 Viruses by Strategic Selection of Envelope Immunogens

Activated PD-1+ CD4+ T cells represent a short-lived part of the viral reservoir and predict poor immunologic recovery upon initiation of ART

Acute Retroviral Syndrome is Associated with High Viral Burden, CD4 Depletion, and Immune Activation in Systemic and Tissue Compartments

Central nervous system safety during brief analytic treatment interruption of antiretroviral therapy within four HIV remission trials: an observational study in acutely treated people living with HIV

Characterization of a novel protective monoclonal antibody that recognizes an epitope common to Vibrio cholerae Ogawa and Inaba serotypes

Co-immunization with multimeric scaffolds and DNA rapidly induces potent autologous HIV-1 neutralizing antibodies and CD8+ T cells

Comparable Antigenicity and Immunogenicity of Oligomeric Forms of a Novel, Acute HIV-1 Subtype C gp145 Envelope for Use in Preclinical and Clinical Vaccine Research

Correction: Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection

Crystal Structure of the Vibrio cholerae Colonization Factor TcpF and Identification of a Functional Immunogenic Site

Delivery strategies for novel vaccine formulations

Distinct biomarker signatures in HIV acute infection associate with viral dynamics and reservoir size

Distribution of HIV RNA in CSF and Blood is linked to CD4/CD8 Ratio During Acute HIV.

Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection

E2 multimeric scaffold for vaccine formulation: immune response by intranasal delivery and transcriptome profile of E2-pulsed dendritic cells

Envelope variants circulating as initial neutralization breadth developed in two HIV-infected subjects stimulate multiclade neutralizing antibodies in rabbits.

Expansion of Inefficient HIV-Specific CD8 T Cells during Acute Infection

Fine epitope signature of antibody neutralization breadth at the HIV-1 envelope CD4-binding site

Genetic mapping of secretion and functional determinants of the Vibrio cholerae TcpF colonization factor

HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies

HLA class II genes modulate vaccine-induced antibody responses to affect HIV-1 acquisition

High Number of Activated CD8+ T Cells Targeting HIV Antigens Are Present in Cerebrospinal Fluid in Acute HIV Infection

Immediate initiation of cART is associated with lower levels of cerebrospinal fluid YKL-40, a marker of microglial activation, in HIV-1 infection.

Immune activation during acute HIV infection and the impact of early antiretroviral therapy

Improvement of antibody responses by HIV envelope DNA and protein co-immunization.

Initiation of antiretroviral therapy before detection of colonic infiltration by HIV reduces viral reservoirs, inflammation and immune activation

Limited Evidence for a Relationship between HIV-1 Glycan Shield Features in Early Infection and the Development of Neutralization Breadth

Liver function test abnormalities in a longitudinal cohort of Thai individuals treated since acute HIV infection

Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual

Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations

Monocyte and CD4+ T cell antiviral and innate responses associated with HIV-1 inflammation and cognitive impairment

Multimeric Epitope-Scaffold HIV Vaccines Target V1V2 and Differentially Tune Polyfunctional Antibody Responses

Multimeric scaffolds displaying the HIV-1 envelope MPER induce MPER-specific antibodies and cross-neutralizing antibodies when co-immunized with gp160 DNA

Neurologic signs and symptoms frequently manifest in acute HIV infection

Normalization of Soluble CD163 Levels After Institution of Antiretroviral Therapy During Acute HIV Infection Tracks with Fewer Neurological Abnormalities

Nutrient-dependent, rapid transition of Vibrio cholerae to coccoid morphology and expression of the toxin co-regulated pilus in this form

Persistent, Albeit Reduced, Chronic Inflammation in Persons Starting Antiretroviral Therapy in Acute HIV Infection

Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor

Protection and attachment of Vibrio cholerae mediated by the toxin-coregulated pilus in the infant mouse model

RV144 HIV-1 vaccination impacts post-infection antibody responses

Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection

SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity

Safety and efficacy of VRC01 broadly neutralising antibodies in adults with acutely treated HIV (RV397): a phase 2, randomised, double-blind, placebo-controlled trial

Safety and immunogenicity of a purified inactivated Zika virus vaccine candidate in adults primed with a Japanese encephalitis virus or yellow fever virus vaccine in the USA: a phase 1, randomised, double-blind, placebo-controlled clinical trial

Sex differences in soluble markers vary before and after the initiation of antiretroviral therapy in chronically HIV-infected individuals

Vaccine delivery to the oral cavity using coated microneedles induces systemic and mucosal immunity

Very Early Initiation of Antiretroviral Therapy During Acute HIV Infection Is Associated With Normalized Levels of Immune Activation Markers in Cerebrospinal Fluid but Not in Plasma

Virological and immunological characteristics of HIV-infected individuals at the earliest stage of infection