List of works - Scott A Handley

A Secreted Viral Nonstructural Protein Determines Intestinal Norovirus Pathogenesis

scientific article published on 23 May 2019

A mouse model for human norovirus

scientific article published on 16 July 2013

Alterations in the oral microbiome in HIV-infected participants after ART administration are influenced by immune status

scientific article published on 28 March 2018

Altered Virome and Bacterial Microbiome in Human Immunodeficiency Virus-Associated Acquired Immunodeficiency Syndrome

scientific article

An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis

scientific article published on 18 February 2020

ApoE isoform– and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathy

scientific article published on 12 January 2023

Autophagy Genes Enhance Murine Gammaherpesvirus 68 Reactivation from Latency by Preventing Virus-Induced Systemic Inflammation

scientific article

Autophagy genes in myeloid cells counteract IFNγ-induced TNF-mediated cell death and fatal TNF-induced shock

scientific article published on 25 July 2019

Construction and evaluation of novel rhesus monkey adenovirus vaccine vectors

scientific article

Discordant transmission of bacteria and viruses from mothers to babies at birth

scientific article published on 10 December 2019

Disease-specific alterations in the enteric virome in inflammatory bowel disease

scientific article

Drowning in Viruses

scientific article published on 01 May 2019

Effect of Antibiotic-Mediated Microbiome Modulation on Rotavirus Vaccine Immunogenicity: A Human, Randomized-Control Proof-of-Concept Trial

scientific article published on 01 August 2018

Growth velocity in children with Environmental Enteric Dysfunction is associated with specific bacterial and viral taxa of the gastrointestinal tract in Malawian children

scientific article published on 23 June 2020

Identification and sequencing of a novel rodent gammaherpesvirus that establishes acute and latent infection in laboratory mice

scientific article published on 5 January 2011

Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity

scientific article published on 26 November 2020

Kingdom-agnostic metagenomics and the importance of complete characterization of enteric microbial communities

scientific article

Lactobacillus-Deficient Cervicovaginal Bacterial Communities Are Associated with Increased HIV Acquisition in Young South African Women

scientific article published on 9 January 2017

LysMD3 is a type II membrane protein without an in vivo role in the response to a range of pathogens.

scientific article published in March 2018

Oral Antibiotic Treatment of Mice Exacerbates the Disease Severity of Multiple Flavivirus Infections

scientific article published in March 2018

Pathogenic simian immunodeficiency virus infection is associated with expansion of the enteric virome

scientific article

Protective efficacy of adenovirus/protein vaccines against SIV challenges in rhesus monkeys

scientific article

Rapid Cloning of Novel Rhesus Adenoviral Vaccine Vectors

scientific article published on 3 January 2018

SIV Infection-Mediated Changes in Gastrointestinal Bacterial Microbiome and Virome Are Associated with Immunodeficiency and Prevented by Vaccination

scientific article

Select autophagy genes maintain quiescence of tissue-resident macrophages and increase susceptibility to Listeria monocytogenes

scientific article published on 20 January 2020

The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis

scientific article published on 08 July 2020

Tropism for tuft cells determines immune promotion of norovirus pathogenesis.

scientific article

UFMylation inhibits the proinflammatory capacity of interferon-γ-activated macrophages

scientific article published on 01 January 2021

Virome biogeography in the lower gastrointestinal tract of rhesus macaques with chronic diarrhea

scientific article published on 20 November 2018

List of works by Scott A Handley

A Secreted Viral Nonstructural Protein Determines Intestinal Norovirus Pathogenesis

A mouse model for human norovirus

Alterations in the oral microbiome in HIV-infected participants after ART administration are influenced by immune status

Altered Virome and Bacterial Microbiome in Human Immunodeficiency Virus-Associated Acquired Immunodeficiency Syndrome

An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis

ApoE isoform– and microbiota-dependent progression of neurodegeneration in a mouse model of tauopathy

Autophagy Genes Enhance Murine Gammaherpesvirus 68 Reactivation from Latency by Preventing Virus-Induced Systemic Inflammation

Autophagy genes in myeloid cells counteract IFNγ-induced TNF-mediated cell death and fatal TNF-induced shock

Construction and evaluation of novel rhesus monkey adenovirus vaccine vectors

Discordant transmission of bacteria and viruses from mothers to babies at birth

Disease-specific alterations in the enteric virome in inflammatory bowel disease

Drowning in Viruses

Effect of Antibiotic-Mediated Microbiome Modulation on Rotavirus Vaccine Immunogenicity: A Human, Randomized-Control Proof-of-Concept Trial

Growth velocity in children with Environmental Enteric Dysfunction is associated with specific bacterial and viral taxa of the gastrointestinal tract in Malawian children

Identification and sequencing of a novel rodent gammaherpesvirus that establishes acute and latent infection in laboratory mice

Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity

Kingdom-agnostic metagenomics and the importance of complete characterization of enteric microbial communities

Lactobacillus-Deficient Cervicovaginal Bacterial Communities Are Associated with Increased HIV Acquisition in Young South African Women

LysMD3 is a type II membrane protein without an in vivo role in the response to a range of pathogens.

Oral Antibiotic Treatment of Mice Exacerbates the Disease Severity of Multiple Flavivirus Infections

Pathogenic simian immunodeficiency virus infection is associated with expansion of the enteric virome

Protective efficacy of adenovirus/protein vaccines against SIV challenges in rhesus monkeys

Rapid Cloning of Novel Rhesus Adenoviral Vaccine Vectors

SIV Infection-Mediated Changes in Gastrointestinal Bacterial Microbiome and Virome Are Associated with Immunodeficiency and Prevented by Vaccination

Select autophagy genes maintain quiescence of tissue-resident macrophages and increase susceptibility to Listeria monocytogenes

The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis

Tropism for tuft cells determines immune promotion of norovirus pathogenesis.

UFMylation inhibits the proinflammatory capacity of interferon-γ-activated macrophages

Virome biogeography in the lower gastrointestinal tract of rhesus macaques with chronic diarrhea