Search filters

List of works by Siegfried Knasmüller

A Helicobacter pylori-associated insulin resistance in asymptomatic sedentary young men does not correlate with inflammatory markers and urine levels of 8-iso-PGF2-α or 1,4-dihydroxynonane mercapturic acid.

scientific article

Anti-Genotoxic Potential of Bilirubin In Vivo: Damage to DNA in Hyperbilirubinemic Human and Animal Models

scientific article published on 27 August 2013

Anticancer activity of the lanthanum compound [tris(1,10-phenanthroline)lanthanum(III)]trithiocyanate (KP772; FFC24).

scientific article published on 15 December 2005

Antioxidant responses to an acute ultra-endurance exercise: impact on DNA stability and indications for an increased need for nutritive antioxidants in the early recovery phase

scientific article published on 19 July 2010

Benzalkonium chloride (BAC) and dimethyldioctadecyl-ammonium bromide (DDAB), two common quaternary ammonium compounds, cause genotoxic effects in mammalian and plant cells at environmentally relevant concentrations

scientific article published on 26 July 2007

Berberine and a Berberis lycium extract inactivate Cdc25A and induce alpha-tubulin acetylation that correlate with HL-60 cell cycle inhibition and apoptosis

scientific article published in January 2010

Binding of heterocyclic aromatic amines by lactic acid bacteria: results of a comprehensive screening trial

scientific article published in March 2008

Chemoprevention of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)-induced colonic and hepatic preneoplastic lesions in the F344 rat by cruciferous vegetables administered simultaneously with the carcinogen

scientific article published in February 2003

Chemoprotective effects of garden cress (Lepidium sativum) and its constituents towards 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ)-induced genotoxic effects and colonic preneoplastic lesions

scientific article

Chromosomal stability in buccal cells was linked to age but not affected by exercise and nutrients - Vienna Active Ageing Study (VAAS), a randomized controlled trial

scientific article published on 24 October 2019

Coffee consumption induces GSTP in plasma and protects lymphocytes against (+/-)-anti-benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide induced DNA-damage: results of controlled human intervention trials

scientific article published on 15 August 2005

Coffee consumption protects human lymphocytes against oxidative and 3-amino-1-methyl-5H-pyrido[4,3-b]indole acetate (Trp-P-2) induced DNA-damage: Results of an experimental study with human volunteers

scientific article published on 12 February 2007

Coffee diterpenes prevent the genotoxic effects of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and N-nitrosodimethylamine in a human derived liver cell line (HepG2).

scientific article published on March 2005

Comparative investigation of multiple organs of mice and rats in the comet assay

scientific article published in May 2002

Consumption of Brussels sprouts protects peripheral human lymphocytes against 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and oxidative DNA-damage: results of a controlled human intervention trial

scientific article

Cytotoxic and DNA-damaging properties of glyphosate and Roundup in human-derived buccal epithelial cells

scientific article published on February 14, 2012

DNA damage in response to an Ironman triathlon.

scientific article published in August 2009

DNA-protective effects of sumach (Rhus coriaria L.), a common spice: results of human and animal studies

scientific article published on 30 October 2008

Detection of genotoxic effects of heavy metal contaminated soils with plant bioassays

scientific article published on 01 December 1998

Detection of mutagenic activity in textiles with Salmonella typhimurium

scientific article published on March 1, 1993

Determination of heterocyclic aromatic amines in beef extract, cooked meat and rat urine by liquid chromatography with coulometric electrode array detection

scientific article published on 01 March 2004

Detoxification of patulin and ochratoxin A, two abundant mycotoxins, by lactic acid bacteria

scientific article published on 24 October 2007

Development and application of test methods for the detection of dietary constituents which protect against heterocyclic aromatic amines

scientific article

Development of test systems for the detection of compounds that prevent the genotoxic effects of heterocyclic aromatic amines: preliminary results with constituents of cruciferous vegetables and other dietary constituents.

scientific article published in January 1999

Dietary induction of phase II enzymes: a promising strategy for protection against DNA-reactive intermediates in man?

scientific article

EGCG Prevents High Fat Diet-Induced Changes in Gut Microbiota, Decreases of DNA Strand Breaks, and Changes in Expression and DNA Methylation of Dnmt1 and MLH1 in C57BL/6J Male Mice

scientific article

Effect of chrysin, a flavonoid compound, on the mutagenic activity of 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine (PhIP) and benzo(a)pyrene (B(a)P) in bacterial and human hepatoma (HepG2) cells

scientific article

Effect of common Brassica vegetables (Brussels sprouts and red cabbage) on the development of preneoplastic lesions induced by 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) in liver and colon of Fischer 344 rats

scientific article published in March 2004

Effect of intestinal microfloras from vegetarians and meat eaters on the genotoxicity of 2-amino-3-methylimidazo[4,5-f]quinoline, a carcinogenic heterocyclic amine

scientific article published in March 2004

Effect of staining procedures on the results of micronucleus assays with exfoliated oral mucosa cells

scientific article published on 01 October 2006

Effects of cruciferous vegetables and their constituents on drug metabolizing enzymes involved in the bioactivation of DNA-reactive dietary carcinogens.

scientific article

Effects of ethanol treatment on DNA damage induced in Escherichia coli K-12 in various organs of mice by N-nitro-sonornicotine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N-nitrosopyrrolidine.

scientific article published in February 1994

Effects of heavy metal contamination of soils on micronucleus induction in Tradescantia and on microbial enzyme activities: a comparative investigation

scientific article published on 01 March 2002

Effects of mustard sprouts and allylisothiocyanate on benzo(a)pyrene-induced DNA damage in human-derived cells: a model study with the single cell gel electrophoresis/Hep G2 assay

scientific article

Effects of phenethyl isothiocyanate on metabolism and on genotoxicity of dimethylnitrosamine and 2-amino-1-methyl-6-phenylimidazo[4, 5-beta]pyridine (PhIP).

scientific article published in February 1996

Effects of unconjugated bilirubin on chromosomal damage in individuals with Gilbert's syndrome measured with the micronucleus cytome assay

scientific article published on 08 August 2012

Effects of β-Carotene and Its Cleavage Products in Primary Pneumocyte Type II Cells

scientific article

Endurance exercise and DNA stability: is there a link to duration and intensity?

scientific article published on 20 February 2009

Enhanced clastogenicity of contaminated groundwater following UV irradiation detected by the Tradescantia micronucleus assay

scientific article published on 01 March 1994

Enhancement of glutathione and g-glutamylcysteine synthetase, the rate limiting enzyme of glutathione synthesis, by chemoprotective plant-derived food and beverage components in the human hepatoma cell line HepG2.

scientific article published on January 2003

Evaluation of the potential of mobile phone specific electromagnetic fields (UMTS) to produce micronuclei in human glioblastoma cell lines

scientific article published on 23 January 2017

Evaluation of the single cell gel electrophoresis assay with human hepatoma (Hep G2) cells

scientific article published on 01 July 2000

Feed‑back loops integrating RELA, SOX18 and FAK mediate the break‑down of the lymph‑endothelial barrier that is triggered by 12(S)‑HETE

scientific article published on 13 February 2020

Gallic acid, a common dietary phenolic protects against high fat diet induced DNA damage

scientific article published on 23 July 2018

Genotoxic and Cytotoxic Effects in Exfoliated Buccal and Nasal Cells of Chromium and Cobalt Exposed Electroplaters

scientific article published on 19 May 2017

Genotoxic and antigenotoxic effects of catechin and tannins from the bark of Hamamelis virginiana L. in metabolically competent, human hepatoma cells (Hep G2) using single cell gel electrophoresis

scientific article published on May 2003

Genotoxic effects of allyl isothiocyanate (AITC) and phenethyl isothiocyanate (PEITC).

scientific article

Genotoxic effects of benzyl isothiocyanate, a natural chemopreventive agent

scientific article published in November 1999

Genotoxic effects of crude juices from Brassica vegetables and juices and extracts from phytopharmaceutical preparations and spices of cruciferous plants origin in bacterial and mammalian cells.

scientific article published on September 1996

Genotoxic effects of dietary and lifestyle related carcinogens in human derived hepatoma (HepG2, Hep3B) cells.

scientific article published on July 2004

Genotoxic effects of heavy metals: Comparative investigation with plant bioassays

article

Genotoxic effects of heterocyclic aromatic amines in human derived hepatoma (HepG2) cells

scientific article

Genotoxic effects of methyl isothiocyanate

scientific article

Genotoxic effects of ochratoxin A in human-derived hepatoma (HepG2) cells

scientific article published in August 2002

Genotoxic effects of the chlorinated hydroxyfuranones 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone and 3,4-dichloro-5-hydroxy-2[5H]-furanone in Tradescantia micronucleus assays

scientific article published in March 1995

Genotoxic effects of three Fusarium mycotoxins, fumonisin B1, moniliformin and vomitoxin in bacteria and in primary cultures of rat hepatocytes

scientific article published on June 13, 1997

Genotoxic effects of wastewater from an oncological ward

scientific article

Genotoxic properties of XLR-11, a widely consumed synthetic cannabinoid, and of the benzoyl indole RCS-4.

scientific article published on 08 February 2016

Genotoxic properties of representatives of alkylindazoles and aminoalkyl-indoles which are consumed as synthetic cannabinoids

scientific article published on 16 March 2015

Genotoxicity of nitrosulfonic acids, nitrobenzoic acids, and nitrobenzylalcohols, pollutants commonly found in ground water near ammunition facilities

scientific article published on March 2006

Harmonisation of the micronucleus assay in human buccal cells--a Human Micronucleus (HUMN) project (www.humn.org) initiative commencing in 2007

scientific article published on 09 December 2006

Heterocyclic aromatic amines--still a challenge for scientists

scientific article published on 01 March 2004

Hydrogen peroxide mediates EGCG-induced antioxidant protection in human keratinocytes

scientific article published on 12 August 2010

Identification of PMN-released Mutagenic Factors in a Co-culture Model for Colitis-associated Cancer.

scientific article

Identification of mutagenic heterocyclic amines (IQ, Trp-P-1 and AalphaC) in the water of the Danube river

scientific article

Impact of Weight Loss Strategies on Obesity-Induced DNA Damage

scientific article published on 14 June 2019

Impact of a synthetic cannabinoid (CP-47,497-C8) on protein expression in human cells: evidence for induction of inflammation and DNA damage

scientific article

Impact of bacteria in dairy products and of the intestinal microflora on the genotoxic and carcinogenic effects of heterocyclic aromatic amines

scientific article

Impact of dietary factors on cancer causes and DNA integrity: new trends and aspects

scientific article published on 01 August 2002

Impact of extended working periods on genomic and telomeric DNA and on inflammatory markers: Results of an intervention study with office workers and carpenters

scientific article published on 05 May 2018

Impact of lactic acid bacteria on oxidative DNA damage in human derived colon cells

scientific article published on 11 September 2007

Impact of obesity and overweight on DNA stability: Few facts and many hypotheses

scientific article published on 11 July 2018

Impact of paper filtered coffee on oxidative DNA-damage: results of a clinical trial

scientific article published on 13 August 2010

Impact of xanthohumol (a prenylated flavonoid from hops) on DNA stability and other health-related biochemical parameters: Results of human intervention trials

scientific article published on 3 February 2016

In situ biomonitoring of the genotoxic effects of mixed industrial emissions using the Tradescantia micronucleus and pollen abortion tests with wild life plants: demonstration of the efficacy of emission controls in an eastern European city

scientific article

In situ monitoring of clastogenicity of ambient air in Bratislava, Slovakia using the Tradescantia micronucleus assay and pollen abortion assays

scientific article

Induction of chromosomal damage in exfoliated buccal and nasal cells of road markers

scientific article published on 01 January 2019

Induction of genotoxic effects by chlorohydroxyfuranones, byproducts of water disinfection, in E. coli K-12 cells recovered from various organs of mice

scientific article published on January 1994

Inhalative exposure to vanadium pentoxide causes DNA damage in workers: results of a multiple end point study.

scientific article published on 31 July 2008

Inhibition of repairable DNA-damage in Escherichia coli K-12 cells recovered from various organs of nitrosamine-treated mice by vitamin A, phenethylisothiocyanate, oleic acid and triolein

scientific article published on September 1, 1992

Inhibition of the genotoxic effects of heterocyclic amines in human derived hepatoma cells by dietary bioantimutagens

scientific article published on 01 July 1997

Instant coffee with high chlorogenic acid levels protects humans against oxidative damage of macromolecules

scientific article published in December 2010

Intake of a resveratrol-containing dietary supplement has no impact on DNA stability in healthy subjects

scientific article published on 5 September 2012

Intestinal microflora plays a crucial role in the genotoxicity of the cooked food mutagen 2-amino-3-methylimidazo [4,5-f]quinoline

scientific article

Investigation of the genotoxic effects of 2-amino-9H-pyrido[2,3-b]indole in different organs of rodents and in human derived cells

scientific article published on March 2004

Investigation of the in vitro toxicological properties of the synthetic cannabimimetic drug CP-47,497-C8.

scientific article published on 28 March 2014

Investigations concerning the long term effects of dietary factors on human health: current topics, methods and new concepts

scientific article published on 01 November 2007

Investigations of the genotoxic properties of two synthetic cathinones (3-MMC, 4-MEC) which are used as psychoactive drugs

scientific article published on 22 July 2016

Investigations on genotoxic effects of groundwater from the Mitterndorfer Senke and from the vicinity of Wiener Neustadt

scientific article published in December 1998

Khat (Catha edulis) consumption causes genotoxic effects in humans

scientific article published in May 2001

Loss of CUL4A expression is underlying cisplatin hypersensitivity in colorectal carcinoma cells with acquired trabectedin resistance

scientific article published on 17 January 2017

Low doses of widely consumed cannabinoids (cannabidiol and cannabidivarin) cause DNA damage and chromosomal aberrations in human-derived cells

scientific article published on 19 October 2018

MSH3-deficiency initiates EMAST without oncogenic transformation of human colon epithelial cells

scientific article

Maintenance of ATP favours apoptosis over necrosis triggered by benzamide riboside

scientific article published in February 2002

Measuring DNA modifications with the comet assay: a compendium of protocols

scientific article published in March 2023

Methamphetamine ("crystal meth") causes induction of DNA damage and chromosomal aberrations in human derived cells

scientific article published on 22 March 2019

Methods for the detection of antioxidants which prevent age related diseases: a critical review with particular emphasis on human intervention studies.

scientific article

Mobile phone specific electromagnetic fields induce transient DNA damage and nucleotide excision repair in serum-deprived human glioblastoma cells.

scientific article published on 12 April 2018

Monitoring, removal and risk assessment of cytostatic drugs in hospital wastewater.

scientific article published in January 2007

Musk ketone enhances benzo(a)pyrene induced mutagenicity in human derived Hep G2 cells

scientific article

Mutation induction and mutation spectra of S. typhimurium TA100 after exposure to isohistidines

scientific article published in September 1996

Mutational spectra of Salmonella typhimurium revertants induced by chlorohydroxyfuranones, byproducts of chlorine disinfection of drinking water

scientific article published in March 1996

No acute and persistent DNA damage after an Ironman triathlon

scientific article published in August 2008

Nuclear anomalies in exfoliated buccal cells in Pakistani cotton weavers

scientific article published on 24 March 2015

Nuclear anomalies in exfoliated buccal cells in healthy and diabetic individuals and the impact of a dietary intervention.

scientific article published on 5 December 2013

Overt Increase of Oxidative Stress and DNA Damage in Murine and Human Colitis and Colitis-associated Neoplasia.

scientific article

Potent protection of gallic acid against DNA oxidation: Results of human and animal experiments

scientific article published on 30 July 2011

Prevention of heterocyclic amine-induced DNA damage in colon and liver of rats by different lactobacillus strains

scientific article published on 11 September 2003

Prevention of oxidative DNA damage in inner organs and lymphocytes of rats by green tea extract

scientific article published on 23 October 2009

Protective effects of Brussels sprouts towards B[a]P-induced DNA damage: a model study with the single-cell gel electrophoresis (SCGE)/Hep G2 assay

scientific article

Protective effects of Brussels sprouts, oligosaccharides and fermented milk towards 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)-induced genotoxicity in the human flora associated F344 rat: role of xenobiotic metabolising enzymes and intestinal micr

scientific article published in March 2004

Protective effects of coffee against induction of DNA damage and pre-neoplastic foci by aflatoxin B₁.

scientific article

Proteome alterations induced in human white blood cells by consumption of Brussels sprouts: Results of a pilot intervention study

scientific article published on 01 January 2008

Proteomic and Metabolomic Analyses Reveal Contrasting Anti-Inflammatory Effects of an Extract of Mucor Racemosus Secondary Metabolites Compared to Dexamethasone

scientific article

Search for compounds that inhibit the genotoxic and carcinogenic effects of heterocyclic aromatic amines

scientific article

Search for dietary antimutagens and anticarcinogens: methodological aspects and extrapolation problems

scientific article

Single cell gel electrophoresis assay: a new technique for human biomonitoring studies

scientific article

Single-cell gel electrophoresis assays with human-derived hepatoma (Hep G2) cells

scientific article published on May 1999

Structurally related mycotoxins ochratoxin A, ochratoxin B, and citrinin differ in their genotoxic activities and in their mode of action in human-derived liver (HepG2) cells: implications for risk assessment.

scientific article

Superoxide generation from Kupffer cells contributes to hepatocarcinogenesis: studies on NADPH oxidase knockout mice

scientific article published on 28 October 2004

Synergistic anticancer activity of arsenic trioxide with erlotinib is based on inhibition of EGFR-mediated DNA double-strand break repair

scientific article published on 2 April 2013

The 10 basic requirements for a scientific paper reporting antioxidant, antimutagenic or anticarcinogenic potential of test substances in in vitro experiments and animal studies in vivo

article

The activities of several detoxication enzymes are differentially induced by juices of garden cress, water cress and mustard in human HepG2 cells.

scientific article

The correlations of glycated hemoglobin and carbohydrate metabolism parameters with heart rate variability in apparently healthy sedentary young male subjects

scientific article published on 3 June 2015

The use of the alkaline comet assay with lymphocytes in human biomonitoring studies

scientific article published on May 2004

Toxic effects of griseofulvin: disease models, mechanisms, and risk assessment.

scientific article

Toxicological profiles of selected synthetic cannabinoids showing high binding affinities to the cannabinoid receptor subtype CB1

scientific article published on March 15, 2013

Tradescantia-micronucleus assay for the assessment of the clastogenicity of Austrian water

scientific article published on May 1999

Use of HuH6 and other human-derived hepatoma lines for the detection of genotoxins: a new hope for laboratory animals?

scientific article

Use of a human-derived liver cell line for the detection of cytoprotective, antigenotoxic and cogenotoxic agents

scientific article

Use of conventional and -omics based methods for health claims of dietary antioxidants: a critical overview.

scientific article

Use of four new human-derived liver-cell lines for the detection of genotoxic compounds in the single-cell gel electrophoresis (SCGE) assay.

scientific article published on 26 August 2008

Use of human-derived liver cell lines for the detection of environmental and dietary genotoxicants; current state of knowledge

scientific article published on May 2004

Use of metabolically competent human hepatoma cells for the detection of mutagens and antimutagens

scientific article published on 01 June 1998

Use of micronucleus assays for the prediction and detection of cervical cancer: a meta-analysis

scientific article published on 11 August 2020

Use of primary blood cells for the assessment of exposure to occupational genotoxicants in human biomonitoring studies

scientific article published on May 2004

Use of single cell gel electrophoresis assays for the detection of DNA-protective effects of dietary factors in humans: recent results and trends

scientific article published on 05 August 2008

Use of the lymphocyte cytokinesis-block micronucleus assay in occupational biomonitoring of genome damage caused by in vivo exposure to chemical genotoxins: Past, present and future

scientific article

Use of the micronucleus assay with exfoliated epithelial cells as a biomarker for monitoring individuals at elevated risk of genetic damage and in chemoprevention trials

scientific article

Vitamin E Modifies High-Fat Diet-Induced Increase of DNA Strand Breaks, and Changes in Expression and DNA Methylation of Dnmt1 and MLH1 in C57BL/6J Male Mice.

scientific article

Well-trained, healthy triathletes experience no adverse health risks regarding oxidative stress and DNA damage by participating in an ultra-endurance event

scientific article published on 18 September 2009

Xanthohumol attenuates tumour cell-mediated breaching of the lymphendothelial barrier and prevents intravasation and metastasis

scientific article published on 17 March 2013

Xanthohumol, a prenylated flavonoid contained in beer, prevents the induction of preneoplastic lesions and DNA damage in liver and colon induced by the heterocyclic aromatic amine amino-3-methyl-imidazo[4,5-f]quinoline (IQ).

scientific article published on 12 June 2010