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List of works by Justin D Lathia

A 4-miRNA signature to predict survival in glioblastomas

scientific article published on 14 November 2017

A Systems Pharmacology Approach Uncovers Wogonoside as an Angiogenesis Inhibitor of Triple-Negative Breast Cancer by Targeting Hedgehog Signaling

scientific article published on 06 June 2019

A Tumor Suppressor Function for Notch Signaling in Forebrain Tumor Subtypes

scientific article published on 5 December 2015

A non-hierarchical organization of tumorigenic NG2 cells in glioblastoma promoted by EGFR

scientific article published on 01 June 2019

ACTR-09. TARGETING MYELOID DERIVED SUPPRESSOR CELLS: PHASE 0/1 TRIAL OF LOW DOSE CAPECITABINE + BEVACIZUMAB IN PATIENTS WITH RECURRENT GLIOBLASTOMA

ADAMDEC1 Maintains a Growth Factor Signaling Loop in Cancer Stem Cells

scientific article published on 21 August 2019

ADAMDEC1 and FGF2/FGFR1 signaling constitute a positive feedback loop to maintain GBM cancer stem cells

scientific article published on 15 November 2019

ATIM-24. TARGETING MYELOID DERIVED SUPPRESSOR CELLS: PHASE 0/1 TRIAL OF LOW DOSE CAPECITABINE + BEVACIZUMAB IN PATIENTS WITH RECURRENT GLIOBLASTOMA

Acute kidney injury leads to inflammation and functional changes in the brain

scientific article published on 2 April 2008

Adhering towards tumorigenicity: altered adhesion mechanisms in glioblastoma cancer stem cells

scientific article published on 12 September 2016

Adhesion- and migration-related side effects of phosphothioated CpG oligodeoxynucleotides

scientific article published on 08 July 2009

An anatomic transcriptional atlas of human glioblastoma.

scientific article

An update on minding the gap in cancer

scientific article published on 24 June 2017

Asymmetric cell division promotes therapeutic resistance in glioblastoma stem cells

scientific article published on 22 December 2020

Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth

scientific article published on 5 March 2012

Brain Cancer Stem Cells in Adults and Children: Cell Biology and Therapeutic Implications

scientific article

Brain tumor initiating cells adapt to restricted nutrition through preferential glucose uptake.

scientific article

CD55 regulates self-renewal and cisplatin resistance in endometrioid tumors.

scientific article published on 24 August 2017

COMP-09. HFE EXPRESSION ALTERS OUTCOMES IN BRAIN TUMORS

CS-21EphA2 PROMOTES INFILTRATIVE INVASION OF GLIOMA STEM CELLS IN VIVO THROUGH CROSSTALK WITH Akt AND REGULATES STEM PROPERTIES

Cadherin-11 Regulates Motility in Normal Cortical Neural Precursors and Glioblastoma ⬇️

scientific article published on August 7, 2013

Cancer Connectors: Connexins, Gap Junctions, and Communication

article by Maksim Sinyuk et al published 2018 in Frontiers in Oncology

Cancer Stem Cell-Secreted Macrophage Migration Inhibitory Factor Stimulates Myeloid Derived Suppressor Cell Function and Facilitates Glioblastoma Immune Evasion

scientific article

Cancer stem cell-specific scavenger receptor CD36 drives glioblastoma progression

scientific article

Cancer stem cells in glioblastoma

scientific article published in June 2015

Cancer stem cells: moving past the controversy

scientific article published in November 2013

Cancer stem cells: targeting the roots of cancer, seeds of metastasis, and sources of therapy resistance

scientific article

Cancer stem cell–immune cell crosstalk in tumour progression

scientific article published in 2021

Chemokine CXCL12 in neurodegenerative diseases: an SOS signal for stem cell-based repair ⬇️

scientific article published on July 10, 2012

Chemokine receptor CXCR4 signaling modulates the growth factor‐induced cell cycle of self‐renewing and multipotent neural progenitor cells ⬇️

scientific article published on January 1, 2011

Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A.

scientific article published on 09 December 2013

Cisplatin induces stemness in ovarian cancer

scientific article published on 20 April 2016

Comparing and Contrasting the Effects of Condensin II Subunit dCAP-D3 Overexpression and Depletion

article

Connexin 43 expression is associated with increased malignancy in prostate cancer cell lines and functions to promote migration

scientific article published on May 2015

Connexins in Cancer: Jekyll or Hyde?

scientific article published on 10 December 2020

Coordination of self-renewal in glioblastoma by integration of adhesion and microRNA signaling

scientific article published on 15 September 2015

Cx25 contributes to leukemia cell communication and chemosensitivity.

scientific article

Cx26 drives self-renewal in triple-negative breast cancer via interaction with NANOG and focal adhesion kinase

scientific article published on 8 February 2018

DIRECT CELL CONTACT BETWEEN BRAIN ENDOTHELIAL CELLS AND GLIOMA STEM CELLS PROMOTES ENDOTHELIAL CELL MIGRATION.

scientific article published in July 2014

DR-07TARGETING EGFR-VIII WITH DICHLOROACETATE IN TEMOZOLOMIDE RESISTANT GLIOBLASTOMA MODELS

scientific article published in November 2014

DRES-19. SEX-BASED DIFFERENCES IN TUMOR RESPONSE TO (TARGETED) THERAPEUTICS: NUANCED SIGNALING MEDIATORS REVEAL TREATMENT OPPORTUNITIES

Deadly teamwork: neural cancer stem cells and the tumor microenvironment

scientific article

Decoding the cancer stem cell hypothesis in glioblastoma

scientific article published on July 2013

Development of a Cx46 Targeting Strategy for Cancer Stem Cells

article

Development of a Fluorescent Reporter System to Delineate Cancer Stem Cells in Triple-Negative Breast Cancer

scientific article published on 15 May 2015

Development of a Sox2 reporter system modeling cellular heterogeneity in glioma

scientific article published on 21 November 2014

Dietary restriction mitigates cocaine-induced alterations of olfactory bulb cellular plasticity and gene expression, and behavior

scientific article

Differential connexin function enhances self-renewal in glioblastoma

scientific article

Direct contact with perivascular tumor cells enhances integrin αvβ3 signaling and migration of endothelial cells

scientific article published on 30 May 2016

Direct in vivo evidence for tumor propagation by glioblastoma cancer stem cells

scientific article

Drak, Drak, Goose: A New Signaling Axis in Glioblastoma

scientific article published on 01 March 2019

Effect of shell type on the in vivo backscatter from polymer-encapsulated microbubbles

scientific article

Endothelial expression of TNF receptor-1 generates a proapoptotic signal inhibited by integrin α6β1 in glioblastoma

scientific article published on 6 March 2012

Erythropoietin Receptor Signaling Through STAT3 Is Required For Glioma Stem Cell Maintenance

scientific article

Expression and prognostic value of JAM-A in gliomas.

scientific article

FGF2: a novel druggable target for glioblastoma?

scientific article published on 16 March 2020

Feedback circuitry between miR-218 repression and RTK activation in glioblastoma.

scientific article published on 5 May 2015

Females have the survival advantage in glioblastoma.

scientific article published on 21 February 2018

Five-Part Pentameric Nanocomplex Shows Improved Efficacy of Doxorubicin in CD44+ Cancer Cells.

scientific article published on 9 November 2017

GENE-19. GAINING A BETTER UNDERSTANDING OF DNA METHYLATION FEATURES ASSOCIATED WITH SEX DIFFERENCES IN GLIOBLASTOMA

GENE-53. SEX-SPECIFIC GENE AND PATHWAY MODELING OF INHERITED GLIOMA RISK

article

Glioblastoma Cancer Stem Cells Evade Innate Immune Suppression of Self-Renewal through Reduced TLR4 Expression

scientific article published on 27 December 2016

Glioblastoma Myeloid-Derived Suppressor Cell Subsets Express Differential Macrophage Migration Inhibitory Factor Receptor Profiles That Can Be Targeted to Reduce Immune Suppression

scientific article published on 18 June 2020

Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth.

scientific article published on March 2013

Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2

scientific article

Gliomas display distinct sex-based differential methylation patterns based on molecular subtype

scientific article published on 08 January 2020

Global immune fingerprinting in glioblastoma patient peripheral blood reveals immune-suppression signatures associated with prognosis

scientific article published on 02 November 2018

Growth Factor Receptors Define Cancer Hierarchies ⬇️

scientific article published on February 11, 2013

Hepatobiliary malignancies have distinct peripheral myeloid-derived suppressor cell signatures and tumor myeloid cell profiles

scientific article published on 02 November 2020

High-Dimensional Analysis of Circulating and Tissue-Derived Myeloid-Derived Suppressor Cells from Patients with Glioblastoma

scientific article published on 01 January 2021

High-Speed Coherent Raman Fingerprint Imaging of Biological Tissues ⬇️

scientific article

High-Throughput Automated Single-Cell Imaging Analysis Reveals Dynamics of Glioblastoma Stem Cell Population During State Transition

scientific article published on 06 February 2019

High-throughput flow cytometry screening reveals a role for junctional adhesion molecule a as a cancer stem cell maintenance factor

scientific article published on 27 December 2013

Holding on to stemness ⬇️

scientific article published on 02 May 2012

Homophilic CD44 interactions mediate tumor cell aggregation and polyclonal metastasis in patient-derived breast cancer models

scientific article published on 25 October 2018

Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells

scientific article published on June 2009

IL-11 drives postsurgical hepatocellular carcinoma recurrence

scientific article published on 08 August 2019

IMMU-70. GLOBAL IMMUNE FINGERPRINTING IN GLIOBLASTOMA REVEALS IMMUNE-SUPPRESSION SIGNATURES ASSOCIATED WITH PROGNOSIS

INTEGRATION OF CANCER STEM CELL MAINTENANCE AND LIPID METABOLISM BY SCAVENGER RECEPTORS.

scientific article published in July 2014

Identifying conserved molecular targets required for cell migration of glioblastoma cancer stem cells

scientific article published on 26 February 2020

In situ monitoring of soil dissolution dynamics: a rapid and simple method for determining worst-case soils for cleaning validation

scientific article published in July 2004

Increased cancer stem cell invasion is mediated by myosin IIB and nuclear translocation

scientific article (publication date: 26 July 2016)

Induction of HEXIM1 activities by HMBA derivative 4a1: Functional consequences and mechanism

scientific article

Inflammation stimulates myelination by transplanted oligodendrocyte precursor cells

scientific article published in September 2006

Inhibition of Farnesyltransferase Potentiates NOTCH-Targeted Therapy against Glioblastoma Stem Cells

scientific article

Insulin-mediated signaling promotes proliferation and survival of glioblastoma through Akt activation

scientific article

Integrin alpha 6 regulates glioblastoma stem cells

scientific article

Integrins are markers of human neural stem cells.

scientific article

Interrogating the interactions between myeloid derived suppressor cells and cancer stem cells in glioblastoma

scientific article published on 7 November 2013

Intravenous immunoglobulin (IVIG) protects the brain against experimental stroke by preventing complement-mediated neuronal cell death

scholarly article

Involvement of notch signaling in wound healing

scientific article

Isolation, Characterization, and Expansion of Cancer Stem Cells

scientific article published on 01 January 2017

JAM-A functions as a female microglial tumor suppressor in glioblastoma

scientific article published on 27 June 2020

Junctional adhesion molecules in cancer: a paradigm for the diverse functions of cell-cell interactions in tumor progression

scientific article published on 14 August 2020

Laminin alpha 2 enables glioblastoma stem cell growth

scientific article published on November 2012

Laminin enhances the growth of human neural stem cells in defined culture media

scientific article

Leptin receptor maintains cancer stem-like properties in triple negative breast cancer cells.

scientific article published on 14 October 2013

Lifelong running reduces oxidative stress and degenerative changes in the testes of mice.

scientific article published on 13 August 2008

Lyn facilitates glioblastoma cell survival under conditions of nutrient deprivation by promoting autophagy

scientific article

MBOAT7-driven phosphatidylinositol remodeling promotes the progression of clear cell renal carcinoma

scientific article published on 03 February 2020

ME-15INTERACTION BETWEEN CANCER STEM CELLS AND MYELOID DERIVED SUPPRESSOR CELLS DRIVES IMMUNOSUPPRESSION AND GLIOBLASTOMA GROWTH.

scientific article

MET Signaling Regulates Glioblastoma Stem Cells ⬇️

scientific article published on May 22, 2012

MR-01MicroRNA-145 REGULATES JAM-A EXPRESSION AND COMPROMISES GLIOBLASTOMA MAINTENANCE.

scientific article published in November 2014

Macropinocytosis of Bevacizumab by Glioblastoma Cells in the Perivascular Niche Affects their Survival

scientific article

Metabolic targeting of EGFRvIII/PDK1 axis in temozolomide resistant glioblastoma

scientific article

Metronomic capecitabine as an immune modulator in glioblastoma patients reduces myeloid-derived suppressor cells

scientific article published on 14 November 2019

Migrating glioma cells express stem cell markers and give rise to new tumors upon xenografting.

scientific article published on 10 August 2016

Modeling mayhem: predicting invasion and proliferation kinetics in IDH1 mutant glioblastoma with mathematical models

scientific article published on 15 April 2014

Molecular targeting of TRF2 suppresses the growth and tumorigenesis of glioblastoma stem cells

scientific article

Monoamine oxidases regulate telencephalic neural progenitors in late embryonic and early postnatal development

scientific article

Multiplex flow cytometry barcoding and antibody arrays identify surface antigen profiles of primary and metastatic colon cancer cell lines

scientific article

Myeloid-derived suppressor cell subsets drive glioblastoma growth in a sex-specific manner

scientific article published on 16 April 2020

NDRG4 is required for cell cycle progression and survival in glioblastoma cells

scientific article published on 10 July 2009

Neural progenitor cells grown on hydrogel surfaces respond to the product of the transgene of encapsulated genetically engineered fibroblasts

scientific article published on 13 October 2010

New Advances and Challenges of Targeting Cancer Stem Cells.

scientific article published on 19 September 2017

Nonreceptor Tyrosine Kinase BMX Maintains Self-Renewal and Tumorigenic Potential of Glioblastoma Stem Cells by Activating STAT3 ⬇️

scientific article published on April 12, 2011

Notch promotes radioresistance of glioma stem cells

scientific article published on 01 January 2010

Notch: from neural development to neurological disorders

scientific article

Optimising gene editing for cancer therapy

scientific article published on 01 March 2020

Outlining involvement of stem cell program in regulation of O6-methylguanine DNA methyltransferase and development of temozolomide resistance in glioblastoma: An Editorial Highlight for 'Transcriptional control of O6 -methylguanine DNA methyltransfe

scientific article

Overview of Cancer Stem Cells and Stemness for Community Oncologists

scientific article published on 30 June 2017

PARP inhibition sensitizes colorectal cancer-initiating cells to chemotherapy

scientific article published on 12 November 2018

Patterns of laminins and integrins in the embryonic ventricular zone of the CNS.

scientific article

Pharmacological Targeting of the Histone Chaperone Complex FACT Preferentially Eliminates Glioblastoma Stem Cells and Prolongs Survival in Preclinical Models

scientific article published on 26 February 2016

Phosphorylation of the histone demethylase KDM5B and regulation of the phenotype of triple negative breast cancer

scientific article published on 27 November 2019

Pivotal role for beta-1 integrin in neurovascular remodelling after ischemic stroke

scientific article published on 21 October 2009

Pivotal role for neuronal Toll-like receptors in ischemic brain injury and functional deficits

scholarly article

Platelet-derived growth factor receptors differentially inform intertumoral and intratumoral heterogeneity

scientific article

Polymeric contrast agent with targeting potential

scientific article published on April 2004

Polymeric ultrasound contrast agents targeted to integrins: importance of process methods and surface density of ligands

scientific article published on February 2007

Preferential Iron Trafficking Characterizes Glioblastoma Stem-like Cells

scientific article

Profilin-1 phosphorylation directs angiocrine expression and glioblastoma progression through HIF-1α accumulation

scientific article

Quiescence and activation of stem and precursor cell populations in the subependymal zone of the mammalian brain are associated with distinct cellular and extracellular matrix signals

scientific article published on July 2010

RBP4-STRA6 Pathway Drives Cancer Stem Cell Maintenance and Mediates High-Fat Diet-Induced Colon Carcinogenesis

scientific article

Recasting the cancer stem cell hypothesis: unification using a continuum model of microenvironmental forces

Receptor channel TRPC6 is a key mediator of Notch-driven glioblastoma growth and invasiveness

scientific article published on 22 December 2009

Regulation of Hepatic Triacylglycerol Metabolism by CGI-58 Does Not Require ATGL Co-activation

scientific article published on 05 July 2016

Release the ballast: Glioblastoma rises above radiation therapy by exporting miR-603 in extracellular vesicles to become treatment-resistant

scientific article published on 02 June 2020

Reporter Systems to Study Cancer Stem Cells

scientific article published on 01 January 2016

Revealing the glioma cancer stem cell interactome, one niche at a time.

scientific article

Role of cysteine-rich 61 protein (CCN1) in macrophage-mediated oncolytic herpes simplex virus clearance

scientific article published on 4 June 2014

SATB2 drives glioblastoma growth by recruiting CBP to promote FOXM1 expression in glioma stem cells

scientific article published on 30 October 2020

SC-10DIVERGENT LIPID METABOLISM DRIVES SELF-RENEWAL IN GLIOBLASTOMA.

scientific article published in November 2014

SC-11DIFFERENTIAL CONNEXIN FUNCTION ENHANCES SELF-RENEWAL IN GLIOBLASTOMA.

scientific article published in November 2014

SC-12CD133 SURFACE EXPRESSION INDICATES ASYMMETRIC INHERITANCE OF SIGNALING RECEPTORS DURING GLIOBLASTOMA CANCER STEM CELL MITOSIS.

scientific article published in November 2014

SC-22GLIOMA STEM CELLS INTERNALIZE BEVACIZUMAB FOUND IN THE PERIVASCULAR NICHE AND TARGET IT FOR RECYCLING OR DEGRADATION

SDF1alpha/CXCR4 signaling, via ERKs and the transcription factor Egr1, induces expression of a 67-kDa form of glutamic acid decarboxylase in embryonic hippocampal neurons

scientific article published on 7 July 2008

STAT3 activation by leptin receptor is essential for TNBC stem cell maintenance

scientific article published on August 2017

STEM-12FATE OF BEVACIZUMAB IN GLIOBLASTOMA.

scientific article published on 9 November 2015

STEM-14. GROWTH FACTOR RECEPTOR CO-INHERITANCE DURING ASYMMETRIC CELL DIVISION DRIVES THE CANCER STEM CELL PHENOTYPE

STEM-21DISRUPTION OF FACILITATES CHROMATIN TRANSCRIPTION (FACT) SYNERGIZES WITH EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) INHIBITION AND PREFERENTIALLY TARGETS GLIOBLASTOMA STEM CELLS.

scientific article

STEM-24. IDENTIFICATION OF SERPIN B3 AS A JUNCTIONAL ADHESION MOLECULE A BINDING PARTNER IN GLIOBLASTOMA CANCER STEM CELLS

Seeing is Believing: Are Cancer Stem Cells the Loch Ness Monster of Tumor Biology? ⬇️

scientific article published on June 1, 2011

Sex differences in GBM revealed by analysis of patient imaging, transcriptome, and survival data

scientific article published on 01 January 2019

Sex differences in cancer incidence and survival: a pan-cancer analysis

scientific article published on 29 April 2020

Sex is an important prognostic factor for glioblastoma but not for nonglioblastoma

scientific article published on 18 May 2019

Sex-specific gene and pathway modeling of inherited glioma risk

article

Sex-specific glioma genome-wide association study identifies new risk locus at 3p21.31 in females, and finds sex-differences in risk at 8q24.21.

scientific article published on 9 May 2018

Sexually dimorphic impact of the iron-regulating gene, HFE, on survival in glioblastoma

scientific article published on 01 January 2020

Squelching glioblastoma stem cells by targeting REST for proteasomal degradation

scientific article published on 11 September 2009

THE ROLE OF MYELOID DERIVED SUPPRESSOR CELLS (MDSCS) IN TUMOR-INDUCED IMMUNOSUPPRESSION IN HUMAN AND MURINE GLIOMAS.

scientific article published in July 2014

TLR2 activation inhibits embryonic neural progenitor cell proliferation

scientific article

TMIC-03LOSS OF DAMAGE-ASSOCIATED MOLECULAR PATTERN SENSING IN CANCER STEM CELLS PROMOTES GLIOBLASTOMA MAINTENANCE.

scientific article published on 9 November 2015

TMIC-51. DEXAMETHASONE DRIVES MYELOID-DERIVED SUPPRESSOR CELL ACCUMULATION IN GLIOBLASTOMA IN A SEX-SPECIFIC MANNER

scientific article published on 5 November 2018

Taking a Toll on Self-Renewal: TLR-Mediated Innate Immune Signaling in Stem Cells

scientific article published on 4 May 2016

Targeting A20 decreases glioma stem cell survival and tumor growth

scientific article

Targeting Cancer Stemness in the Clinic: From Hype to Hope

scientific article published on 27 December 2018

Targeting interleukin 6 signaling suppresses glioma stem cell survival and tumor growth

scientific article

Tetraspanin CD9 stabilizes gp130 by preventing its ubiquitin-dependent lysosomal degradation to promote STAT3 activation in glioma stem cells

scientific article published on 14 October 2016

The Clinical Impact of Cancer Stem Cells

scientific article published on 17 December 2019

The Lgr5 transgene is expressed specifically in glycinergic amacrine cells in the mouse retina

scientific article

The dystroglycan receptor maintains glioma stem cells in the vascular niche

scientific article published on 28 August 2019

The evolution of the cancer stem cell state in glioblastoma - emerging insights into the next-generation of functional interactions

scientific article published on 11 November 2020

The intersection of cancer, cancer stem cells, and the immune system: therapeutic opportunities

scientific article

The malignant social network: cell-cell adhesion and communication in cancer stem cells

scientific article published on July 2012

The microenvironment of the embryonic neural stem cell: lessons from adult niches?

scientific article published on December 2007

The neural stem cell microenvironment

scientific article published on 9 July 2010

The p38 signaling pathway mediates quiescence of glioma stem cells by regulating epidermal growth factor receptor trafficking

scientific article

The role of cancer stem cells in glioblastoma

scientific article published on December 2014

Therapeutic Injury and Tumor Regrowth: Tumor Resection and Radiation Establish the Recurrent Glioblastoma Microenvironment

scientific article published on 20 April 2018

Therapeutic strategies to induce ERα in luminal breast cancer to enhance tamoxifen efficacy

scientific article published on 01 August 2019

Thy-1 predicts poor prognosis and is associated with self-renewal in ovarian cancer

scientific article published on 17 November 2019

Toll-like receptor 3 is a negative regulator of embryonic neural progenitor cell proliferation

scientific article published on December 2008

Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid beta-peptide and the membrane lipid peroxidation product 4-hydroxynonenal

scientific article published on 29 May 2008

Toll-like receptors in neurodegeneration.

scientific article published on 12 September 2008

Transferrin receptor-1 and ferritin heavy and light chains in astrocytic brain tumors: Expression and prognostic value

scientific article published on 24 August 2017

Triggering Receptor Expressed on Myeloid Cells 2 Deficiency Alters Acute Macrophage Distribution and Improves Recovery after Traumatic Brain Injury

scientific article published on 15 March 2016

Twisted tango: brain tumor neurovascular interactions

scientific article

Ultrasound degradation of novel polymer contrast agents

scientific article published in January 2004

beta1 integrin maintains integrity of the embryonic neocortical stem cell niche

scientific article (publication date: August 2009)

c-Myc is required for maintenance of glioma cancer stem cells

scientific article

miR-218 opposes a critical RTK-HIF pathway in mesenchymal glioblastoma

scientific article published on 24 December 2013

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