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List of works by Brian Czerniecki

99mTc-human serum albumin: an effective radiotracer for identifying sentinel lymph nodes in melanoma.

scientific article

A brief report of toxicity end points of HER2 vaccines for the treatment of patients with HER2 breast cancer

article

A cost-utility analysis comparing large volume displacement oncoplastic surgery to mastectomy with free flap reconstruction in the treatment of breast cancer

scientific article published on 31 January 2019

A dendritic cell vaccine pulsed with autologous hypochlorous acid-oxidized ovarian cancer lysate primes effective broad antitumor immunity: from bench to bedside

scientific article

A human ErbB2-specific T-cell receptor confers potent antitumor effector functions in genetically engineered primary cytotoxic lymphocytes

scientific article

A novel dendritic cell-based immunization approach for the induction of durable Th1-polarized anti-HER-2/neu responses in women with early breast cancer.

scientific article published on January 2012

A phase 1 trial of talimogene laherparepvec in combination with neoadjuvant chemotherapy for the treatment of non-metastatic triple-negative breast cancer

scientific article published on 20 November 2020

Accuracy of sentinel lymph node biopsy in patients with large primary breast tumors

scientific article published in June 2000

Active macromolecule uptake by lymph node antigen-presenting cells: a novel mechanism in determining sentinel lymph node status

scientific article published in March 2000

Addition of anti-estrogen therapy to anti-HER2 dendritic cell vaccination improves regional nodal immune response and pathologic complete response rate in patients with ERpos/HER2pos early breast cancer

scientific article published on July 2016

Anti-HER2 CD4(+) T-helper type 1 response is a novel immune correlate to pathologic response following neoadjuvant therapy in HER2-positive breast cancer

scientific article published on 23 May 2015

Anti-HER2 CD4+ T-Helper Type 1 Immune Response is Superior to Breast MRI for Assessing Response to Neoadjuvant Therapy in Patients with HER2-Positive Breast Cancer

scientific article published on 8 November 2016

Association of Depressed Anti-HER2 T-Helper Type 1 Response With Recurrence in Patients With Completely Treated HER2-Positive Breast Cancer: Role for Immune Monitoring.

scientific article published on 30 December 2015

Asymptomatic changes in cardiac function can occur in ductal carcinoma-in-situ patients following treatment with HER-2/neu-pulsed dendritic cell vaccines

scientific article published on October 2009

Biopsy findings after breast conservation therapy for early-stage invasive breast cancer

scientific article published on 4 June 2007

Boosting anti-HER2 CD4 T-helper responses in HER2 expressing ductal carcinoma in situ

scientific article

Breast cancer detection based on incremental biochemical and physiological properties of breast cancers: a six-year, two-site study

scientific article published on 01 August 2005

Breast leptomeningeal disease: a review of current practices and updates on management

scientific article published on 17 June 2019

CD4(+) T-Helper Type 1 Cytokines and Trastuzumab Facilitate CD8(+) T-cell Targeting of HER2/neu-Expressing Cancers

scientific article

CD4+ Th1 to the rescue in HER-2+ breast cancer

scientific article published on 02 May 2018

Calcium ionophore pre-treatment induces type-1 polarized DCs with enhanced T cell stimulatory function and IL-12 production

scientific article published on 7 November 2013

Calcium ionophore-treated myeloid cells acquire many dendritic cell characteristics independent of prior differentiation state, transformation status, or sensitivity to biologic agents

scientific article published on 01 August 1999

Calcium ionophore-treated peripheral blood monocytes and dendritic cells rapidly display characteristics of activated dendritic cells

scientific article published on 01 October 1997

Changes in the surgical management of patients with breast carcinoma based on preoperative magnetic resonance imaging

scientific article

Circulating tumor cells in breast cancer patients: an evolving role in patient prognosis and disease progression

scientific article

Clark level risk stratifies patients with mitogenic thin melanomas for sentinel lymph node biopsy

scientific article published on 12 October 2013

Clinical development of immunotherapies for HER2+ breast cancer: a review of HER2-directed monoclonal antibodies and beyond

scientific article published on 12 March 2020

Clinical outcomes of breast leptomeningeal disease treated with intrathecal trastuzumab, intrathecal chemotherapy, or whole brain radiation therapy

scientific article published on 11 March 2019

Combining innate immunity with radiation therapy for cancer treatment

scientific article

Computer aided automatic detection of malignant lesions in diffuse optical mammography ⬇️

scientific article

Cutting edge: innate immune system discriminates between RNA containing bacterial versus eukaryotic structural features that prime for high-level IL-12 secretion by dendritic cells

scientific article published on April 2004

Cyclosporin A-induced fibroadenomas of the breast: report of five cases

scientific article published in August 2001

DCIS in BRCA1 and BRCA2 mutation carriers: prevalence, phenotype, and expression of oncodrivers C-MET and HER3.

scientific article

Day-4 myeloid dendritic cells pulsed with whole tumor lysate are highly immunogenic and elicit potent anti-tumor responses

scientific article

Dendritic Cell Vaccination Enhances Immune Responses and Induces Regression of HER2pos DCIS Independent of Route: Results of Randomized Selection Design Trial

scientific article

Dendritic Cell-Induced Th1 and Th17 Cell Differentiation for Cancer Therapy

scientific article published on 21 November 2013

Dendritic cell-based vaccines: barriers and opportunities

scientific article

Dendritic cells in melanoma immunotherapy

scientific article

Dendritic cells matured in the presence of TLR ligands overcome the immunosuppressive functions of regulatory T cells

scientific article published on 6 January 2014

Developing dendritic cell-based therapies to condition immune responses to novel oncogenic proteins and stem cells

scientific article published on September 2009

Development of vaccines for high-risk ductal carcinoma in situ of the breast

scientific article published on July 2007

Diagnosis of Melanoma

scientific article published on 01 January 2011

Differential production of IL-23 and IL-12 by myeloid-derived dendritic cells in response to TLR agonists

scientific article published in October 2008

Differentiation of benign and malignant breast tumors by in-vivo three-dimensional parallel-plate diffuse optical tomography

scientific article published on March 2009

Diffuse optical measurement of blood flow in breast tumors

scientific article published on 01 November 2005

Diffuse optical tomography of breast cancer during neoadjuvant chemotherapy: a case study with comparison to MRI.

scientific article

Diverse functional activity of CD83+ monocyte-derived dendritic cells and the implications for cancer vaccines

scientific article

Dual time point 18F-FDG PET imaging detects breast cancer with high sensitivity and correlates well with histologic subtypes.

scientific article published in September 2006

Ductal carcinoma in situ: state of the science and roadmap to advance the field

scientific article published on 08 December 2008

Early Postoperative Outcomes in Breast Conservation Surgery Versus Simple Mastectomy with Implant Reconstruction: A NSQIP Analysis of 11,645 Patients

scientific article published on 29 July 2015

Early postoperative outcomes in lumpectomy versus simple mastectomy

scientific article published on 4 February 2015

Effect of multiple activation stimuli on the generation of Th1-polarizing dendritic cells

scientific article published on 15 October 2010

Evaluating the Risk of Upstaging HER2-Positive DCIS to Invasive Breast Cancer

scientific article published on August 2017

Extracellular ATP and Toll-like receptor 2 agonists trigger in human monocytes an activation program that favors T helper 17

scientific article

Factors influencing surgical and adjuvant therapy in stage I breast cancer: a SEER 18 database analysis

scientific article published on 8 November 2012

Feasibility of Axillary Lymph Node Localization and Excision Using Radar Reflector Localization

scientific article published on 06 August 2020

HER-2 pulsed dendritic cell vaccine can eliminate HER-2 expression and impact ductal carcinoma in situ.

scientific article published on 17 January 2012

HER-2/neu overexpression as a predictor for the transition from in situ to invasive breast cancer

scientific article published on 21 April 2009

HER3 Expression Is a Marker of Tumor Progression in Premalignant Lesions of the Gastroesophageal Junction

scientific article

Heterodyne frequency-domain multispectral diffuse optical tomography of breast cancer in the parallel-plane transmission geometry

scientific article published on July 2016

High-avidity antitumor T-cell generation by toll receptor 8-primed, myeloid- derived dendritic cells is mediated by IL-12 production.

scientific article

Histological Immune Response Patterns in Sentinel Lymph Nodes Involved by Metastatic Melanoma and Prognostic Significance

scientific article published on 15 February 2018

Human leukocyte antigen-A2-restricted CTL responses to mutated BRAF peptides in melanoma patients.

scientific article published on March 2006

Identification of Patients with Intermediate Thickness Melanoma at Low Risk for Sentinel Lymph Node Positivity

scientific article

Identification of high-risk patients among those diagnosed with thin cutaneous melanomas

scientific article published on 01 March 2007

Immediate reconstruction following nipple-sparing mastectomy: one option for young breast cancer patients with early stage disease

scientific article published on June 2013

Immune interconnectivity of anatomically distant tumors as a potential mediator of systemic responses to local therapy.

scientific article published on 21 June 2018

Immunohistochemistry with pancytokeratins improves the sensitivity of sentinel lymph node biopsy in patients with breast carcinoma

scientific article

Immunologic Consequences of Sequencing Cancer Radiotherapy and Surgery

scientific article published on 01 April 2019

Immunotherapy for Breast Cancer is Finally at the Doorstep: Immunotherapy in Breast Cancer

scientific article published on 16 July 2018

Immunotherapy in breast cancer: Current status and future directions

scientific article published on 02 May 2019

Implant-sparing Mastectomy: An Alternative for Women Undergoing Mastectomy With Retropectoral Implants

scientific article published on 03 September 2019

Incidence of sentinel node metastasis in patients with thin primary melanoma (< or = 1 mm) with vertical growth phase

scientific article published in May 2000

Inhibition of CD4+CD25+ regulatory T cell function and conversion into Th1-like effectors by a Toll-like receptor-activated dendritic cell vaccine

scientific article

Interference-Free HER2 ECD as a Serum Biomarker in Breast Cancer

scientific article

Intranodal Administration of Peptide-Pulsed Mature Dendritic Cell Vaccines Results in Superior CD8+T-Cell Function in Melanoma Patients ⬇️

scientific article published on October 15, 2003

It's all in for the HER family in tumorigenesis

scientific article published in January 2010

Local immune response predicts survival in patients with thick (t4) melanomas

scientific article

Locally recurrent malignant melanoma characteristics and outcomes: a single-institution study

scientific article

Loss of Anti-HER-3 CD4+ T-Helper Type 1 Immunity Occurs in Breast Tumorigenesis and is Negatively Associated with Outcomes.

scientific article published on 23 September 2016

MR imaging in patients with nipple discharge: initial experience

scientific article published on 01 July 2000

MR imaging of the breast in patients with invasive lobular carcinoma

scientific article published on 01 February 2001

MR imaging screening of the contralateral breast in patients with newly diagnosed breast cancer: preliminary results

scientific article published on 31 January 2003

MRI before reexcision surgery in patients with breast cancer

scientific article published on 01 February 2004

Macroscopic optical physiological parameters correlate with microscopic proliferation and vessel area breast cancer signatures.

scientific article published on 27 May 2015

Magnetic resonance imaging-guided biopsy of mammographically and clinically occult breast lesions

scientific article

Mammographic Appearance of Recurrent Breast Cancer after Breast Conservation Therapy

scientific article published on 01 February 2008

Management of brain metastases in breast cancer: a review of current practices and emerging treatments

scientific article published on 06 February 2020

Mature CD83(+) dendritic cells infected with recombinant gp100 vaccinia virus stimulate potent antimelanoma T cells

scientific article

Method of Primary Tumor Detection as a Risk Factor for Local and Distant Recurrence After Breast-Conservation Treatment for Early-Stage Breast Cancer

scientific article published on 01 April 2008

Mitotic rate as a predictor of sentinel lymph node positivity in patients with thin melanomas.

scientific article

Neoadjuvant radiotherapy of early-stage breast cancer and long-term disease-free survival

scientific article

Novel strategy to identify MHC class II-promiscuous CD4+ peptides from tumor antigens for utilization in vaccination

scientific article

Occult Breast Carcinoma Presenting as Scalp Metastasis

scientific article published in September 2017

Oncodriver inhibition and CD4+ Th1 cytokines cooperate through Stat1 activation to induce tumor senescence and apoptosis in HER2+ and triple negative breast cancer: implications for combining immune and targeted therapies.

scientific article

Oncoplastic Surgery: Keeping It Simple With 5 Essential Volume Displacement Techniques for Breast Conservation in a Patient With Moderate- to Large-Sized Breasts

scientific article published in October 2017

Optical malignancy parameters for monitoring progression of breast cancer neoadjuvant chemotherapy

scientific article published on 14 December 2012

Optically measured microvascular blood flow contrast of malignant breast tumors

scientific article

Optimizing dendritic cell-based approaches for cancer immunotherapy

scientific article

Optimizing parameters for clinical-scale production of high IL-12 secreting dendritic cells pulsed with oxidized whole tumor cell lysate

scientific article published on 14 November 2011

Outcome after treatment of patients with mammographically occult, magnetic resonance imaging-detected breast cancer presenting with axillary lymphadenopathy

scientific article published on 01 April 2004

Outcomes After Oncoplastic Breast-Conserving Surgery in Breast Cancer Patients: A Systematic Literature Review

scientific article published on 29 June 2016

Performance and Practice Guideline for the Use of Neoadjuvant Systemic Therapy in the Management of Breast Cancer

scientific article published on 30 July 2015

Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancer.

scientific article published in April 2018

Personalizing Radiation Treatment Delivery in the Management of Breast Cancer.

scientific article published on 10 June 2018

Predicting sentinel node status in AJCC stage I/II primary cutaneous melanoma

scientific article published on 01 November 2006

Predictors of false negative sentinel lymph node biopsy in trunk and extremity melanoma.

scientific article published on 26 June 2017

Predictors of regional nodal disease in patients with thin melanomas

scientific article published on 07 March 2006

Preferential involvement of CX chemokine receptor 4 and CX chemokine ligand 12 in T-cell migration toward melanoma cells.

scientific article published on 4 October 2006

Prognosis of patients with melanoma and microsatellitosis undergoing sentinel lymph node biopsy.

scientific article

Progressive loss of anti-HER2 CD4(+) T-helper type 1 response in breast tumorigenesis and the potential for immune restoration

scientific article

Racial disparities in immediate breast reconstruction after mastectomy: impact of state and federal health policy changes

scientific article published on 3 October 2012

Racial disparities in the use of outpatient mastectomy

scientific article

Radiation as immunomodulator: implications for dendritic cell-based immunotherapy

scientific article

Rapid high efficiency sensitization of CD8+ T cells to tumor antigens by dendritic cells leads to enhanced functional avidity and direct tumor recognition through an IL-12-dependent mechanism

scientific article published in September 2003

Rationale for a Multimodality Strategy to Enhance the Efficacy of Dendritic Cell-Based Cancer Immunotherapy

scientific article

Reengineering dendritic cell-based anti-cancer vaccines

scientific article published on April 2008

Regional nodal metastatic disease is the strongest predictor of survival in patients with thin vertical growth phase melanomas: a case for SLN Staging biopsy in these patients.

scientific article published on 7 February 2007

Repeat operative sentinel lymph node biopsy

scientific article published on 01 February 2006

Resident and Fellow Participation in Breast Surgery: An American College of Surgeons NSQIP Clinical Outcomes Analysis

scientific article published on 20 August 2015

Residents' Experience in Breast Cancer Care.

scientific article published on 25 June 2015

Response to HER-2 pulsed DC1 vaccines is predicted by both HER-2 and estrogen receptor expression in DCIS.

scientific article published on 13 July 2013

Restoring Lost Anti-HER-2 Th1 Immunity in Breast Cancer: A Crucial Role for Th1 Cytokines in Therapy and Prevention

scientific article

Restoring anti-oncodriver Th1 responses with dendritic cell vaccines in HER2/neu-positive breast cancer: progress and potential

scientific article published on October 2016

Revolutionary impact of lymphoscintigraphy and intraoperative sentinel node mapping in the clinical practice of oncology

scientific article

STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34pos cells into tumor-competent dendritic cells

scientific article published on 24 June 2008

Sartorius transposition during inguinal lymphadenectomy for melanoma

scientific article

Sentinel lymph node biopsy in breast cancer: a work in progress

scientific article

Sentinel lymph node biopsy with metastasis: can axillary dissection be avoided in some patients with breast cancer?

scientific article

Sequential Anti-PD1 Therapy Following Dendritic Cell Vaccination Improves Survival in a HER2 Mammary Carcinoma Model and Identifies a Critical Role for CD4 T Cells in Mediating the Response

scientific article published on 14 August 2019

Shared MHC class II-dependent melanoma ribosomal protein L8 identified by phage display

article

Skin-sparing mastectomy and immediate reconstruction is an acceptable treatment option for patients with high-risk breast carcinoma

scientific article

Stem cells and cancer immunotherapy: Arrowhead’s 2nd annual cancer immunotherapy conference.

scientific article

Subareolar and peritumoral injection identify similar sentinel nodes for breast cancer

scientific article published in March 2002

Sunitinib Combined with Th1 Cytokines Potentiates Apoptosis in Human Breast Cancer Cells and Suppresses Tumor Growth in a Murine Model of HER-2<sup>pos</sup> Breast Cancer

scientific article published on 14 April 2021

T-cell adoptive therapy of tumors: mechanisms of improved therapeutic performance.

scientific article

T-helper 1-type cytokines induce apoptosis and loss of HER-family oncodriver expression in murine and human breast cancer cells

scientific article published on 15 October 2019

Targeting HER-2/neu in early breast cancer development using dendritic cells with staged interleukin-12 burst secretion.

scientific article

Th1 cytokine interferon gamma improves response in HER2 breast cancer by modulating the ubiquitin proteasomal pathway

scientific article published on 04 January 2021

Th1 cytokines in conjunction with pharmacological Akt inhibition potentiate apoptosis of breast cancer cells in vitro and suppress tumor growth in vivo

scientific article published on 28 July 2020

Th1 cytokines sensitize HER-expressing breast cancer cells to lapatinib

scientific article published in PLoS ONE

The Role of Lymphatic Mapping and Sentinel Lymph Node Biopsy in the Staging of Breast Cancer

scientific article published on 01 July 2009

The Role of PET and PET/CT in the Surgical Management of Breast Cancer: A Review

scientific article published on July 2009

The effects of estrogen, progesterone, and C-erbB-2 receptor states on 18F-FDG uptake of primary breast cancer lesions.

scientific article

The impact of a multidisciplinary breast cancer center on recommendations for patient management: the University of Pennsylvania experience

scientific article

The impact of preoperative magnetic resonance imaging and lumpectomy cavity shavings on re-excision rate in pure ductal carcinoma in situ-A single institution's experience.

scientific article published on 11 November 2017

The significance of HER-2/neu receptor positivity and immunophenotype in ductal carcinoma in situ with early invasive disease

scientific article

Thin Melanoma with Nodal Involvement: Analysis of Demographic, Pathologic, and Treatment Factors with Regard to Prognosis

scientific article published on 2 November 2016

Thin primary cutaneous malignant melanoma: a prognostic tree for 10-year metastasis is more accurate than American Joint Committee on Cancer staging

scientific article published on 09 August 2004

Transected thin melanoma: Implications for sentinel lymph node staging.

scientific article

Trends in immediate breast reconstruction across insurance groups after enactment of breast cancer legislation

scientific article

Tumor-associated B-cells induce tumor heterogeneity and therapy resistance

scientific article published on 19 September 2017

Type I-polarized BRAF-pulsed dendritic cells induce antigen-specific CD8+ T cells that impact BRAF-mutant murine melanoma

scientific article published on 8 October 2015

Use of radiotracer for sentinel lymph node mapping in breast cancer optimizes staging independent of site of administration.

scientific article published on September 2006

Utilizing the genomically adjusted radiation dose (GARD) to personalize adjuvant radiotherapy in triple negative breast cancer management

scientific article published on 12 August 2019

Vaccine Therapies for Breast Cancer

scientific article published on 05 April 2019

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