List of works - Yan Niu

2-Substituted-thio-N-(4-substituted-thiazol/1H-imidazol-2-yl)acetamides as BACE1 inhibitors: Synthesis, biological evaluation and docking studies.

scientific article

4-Oxo-1,4-dihydro-quinoline-3-carboxamides as BACE-1 inhibitors: synthesis, biological evaluation and docking studies

scientific article

A Smart Fluorescent Probe for NO Detection and Application in Myocardial Fibrosis Imaging

scientific article published on 11 March 2020

Delanzomib, a novel proteasome inhibitor, sensitizes breast cancer cells to doxorubicin-induced apoptosis

scientific article published on 18 March 2019

Design and synthesis of tripeptidyl furylketones as selective inhibitors against the β5 subunit of human 20S proteasome

scientific article published on 19 February 2020

Design, synthesis and biological evaluation of cobalt(II)-Schiff base complexes as ATP-noncompetitive MEK1 inhibitors

scientific article published on 30 March 2019

Design, synthesis, and biological evaluation of 4-aminopyrimidine or 4,6-diaminopyrimidine derivatives as beta amyloid cleaving enzyme-1 inhibitors

scientific article published on 12 February 2019

Development of novel proteasome inhibitors based on phthalazinone scaffold

scientific article published on 23 April 2016

Discovery of a cobalt complex with high MEK1 binding affinity

scientific article published on 10 March 2017

Discovery of carbazole derivatives as novel allosteric MEK inhibitors by pharmacophore modeling and virtual screening

scientific article published on 15 June 2019

Rational Design of Fluorescent Phthalazinone Derivatives for One- and Two-Photon Imaging

scientific article published on 21 July 2016

Relay Catalysis by a Multifunctional Cu Catalyst in a Tandem Dehydro-/Dehalogenation Sequence along with N-Arylation ⬇️

scientific article published on May 14, 2013

Substituted 3-Benzylcoumarins as Allosteric MEK1 Inhibitors: Design, Synthesis and Biological Evaluation as Antiviral Agents ⬇️

scientific article published on May 21, 2013

Substituted 3-benzylcoumarins 13 and 14 suppress enterovirus A71 replication by impairing viral 2A dependent IRES-driven translation

scientific article published on 11 October 2018

Synthesis, bioactivity, docking and molecular dynamics studies of furan-based peptides as 20S proteasome inhibitors

scientific article

The Discovery of Novel β‐Secretase Inhibitors: Pharmacophore Modeling, Virtual Screening, and Docking Studies ⬇️

scientific article published on April 17, 2012

List of works by Yan Niu

2-Substituted-thio-N-(4-substituted-thiazol/1H-imidazol-2-yl)acetamides as BACE1 inhibitors: Synthesis, biological evaluation and docking studies.

4-Oxo-1,4-dihydro-quinoline-3-carboxamides as BACE-1 inhibitors: synthesis, biological evaluation and docking studies

A Smart Fluorescent Probe for NO Detection and Application in Myocardial Fibrosis Imaging

Delanzomib, a novel proteasome inhibitor, sensitizes breast cancer cells to doxorubicin-induced apoptosis

Design and synthesis of tripeptidyl furylketones as selective inhibitors against the β5 subunit of human 20S proteasome

Design, synthesis and biological evaluation of cobalt(II)-Schiff base complexes as ATP-noncompetitive MEK1 inhibitors

Design, synthesis, and biological evaluation of 4-aminopyrimidine or 4,6-diaminopyrimidine derivatives as beta amyloid cleaving enzyme-1 inhibitors

Development of novel proteasome inhibitors based on phthalazinone scaffold

Discovery of a cobalt complex with high MEK1 binding affinity

Discovery of carbazole derivatives as novel allosteric MEK inhibitors by pharmacophore modeling and virtual screening

Rational Design of Fluorescent Phthalazinone Derivatives for One- and Two-Photon Imaging

Relay Catalysis by a Multifunctional Cu Catalyst in a Tandem Dehydro-/Dehalogenation Sequence along with N-Arylation ⬇️

Substituted 3-Benzylcoumarins as Allosteric MEK1 Inhibitors: Design, Synthesis and Biological Evaluation as Antiviral Agents ⬇️

Substituted 3-benzylcoumarins 13 and 14 suppress enterovirus A71 replication by impairing viral 2A dependent IRES-driven translation

Synthesis, bioactivity, docking and molecular dynamics studies of furan-based peptides as 20S proteasome inhibitors

The Discovery of Novel β‐Secretase Inhibitors: Pharmacophore Modeling, Virtual Screening, and Docking Studies ⬇️