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List of works by Mary V Relling

6MP adherence in a multiracial cohort of children with acute lymphoblastic leukemia: a Children's Oncology Group study

scientific article

A PAI-1 (SERPINE1) polymorphism predicts osteonecrosis in children with acute lymphoblastic leukemia: a report from the Children's Oncology Group

scientific article

A comprehensive evaluation of collapsing methods using simulated and real data: excellent annotation of functionality and large sample sizes required

scientific article

A genome-wide association study of susceptibility to acute lymphoblastic leukemia in adolescents and young adults

scientific article

ARID5B genetic polymorphisms contribute to racial disparities in the incidence and treatment outcome of childhood acute lymphoblastic leukemia

scientific article

Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia

scientific article

Asparaginase formulation impacts hypertriglyceridemia during therapy for acute lymphoblastic leukemia

scientific article published on 14 October 2019

Association of GSTM1 null variant with anthracycline-related cardiomyopathy after childhood cancer-A Children's Oncology Group ALTE03N1 report

scientific article published on 15 May 2020

Between-course targeting of methotrexate exposure using pharmacokinetically guided dosage adjustments ⬇️

scientific article published on June 13, 2013

Bloodstream infections exacerbate incidence and severity of symptomatic glucocorticoid-induced osteonecrosis

scientific article published on 13 February 2019

Body mass index does not influence pharmacokinetics or outcome of treatment in children with acute lymphoblastic leukemia

scientific article published on 17 August 2006

CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes

scientific article

Cancer pharmacogenomics and pharmacoepidemiology: setting a research agenda to accelerate translation

scientific article

Chemotherapeutic agents circumvent emergence of dasatinib-resistant BCR-ABL kinase mutations in a precise mouse model of Philadelphia chromosome–positive acute lymphoblastic leukemia ⬇️

scientific article published on January 24, 2011

Clinical utility of sequential minimal residual disease measurements in the context of risk-based therapy in childhood acute lymphoblastic leukaemia: a prospective study.

scientific article

Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics

scientific article

Concordant gene expression in leukemia cells and normal leukocytes is associated with germline cis-SNPs

scientific article

Cumulative incidence of secondary neoplasms as a first event after childhood acute lymphoblastic leukemia

scientific article

Deregulation of DUX4 and ERG in acute lymphoblastic leukemia

scientific article published on 24 October 2016

Development of a postgraduate year 2 pharmacy residency in clinical pharmacogenetics

scientific article

Differential effects of thiopurine methyltransferase (TPMT) and multidrug resistance-associated protein gene 4 (MRP4) on mercaptopurine toxicity.

scientific article published on 16 June 2017

Effect of allopurinol versus urate oxidase on methotrexate pharmacokinetics in children with newly diagnosed acute lymphoblastic leukemia

scientific article

Evidence synthesis and guideline development in genomic medicine: current status and future prospects

scientific article

Expression of SMARCB1 modulates steroid sensitivity in human lymphoblastoid cells: identification of a promoter SNP that alters PARP1 binding and SMARCB1 expression

scientific article

Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics

scientific article

Gene expression signatures predictive of early response and outcome in high-risk childhood acute lymphoblastic leukemia: A Children's Oncology Group Study [corrected]

scientific article published on September 2008

Genetic nondiscrimination legislation: a critical prerequisite for pharmacogenomics data sharing

scientific article

Genetic predictors of glucocorticoid-induced hypertension in children with acute lymphoblastic leukemia

scientific article

Genetic studies of a cluster of acute lymphoblastic leukemia cases in Churchill County, Nevada

scientific article

Genetics of glucocorticoid-associated osteonecrosis in children with acute lymphoblastic leukemia

scientific article

Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

scientific article (publication date: 12 April 2007)

Genome-wide association studies in pharmacogenomics: successes and lessons

scientific article

Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemia

scientific journal article

Genome-wide copy number profiling reveals molecular evolution from diagnosis to relapse in childhood acute lymphoblastic leukemia

scientific article published on 02 September 2008

Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia

scientific journal article

Genomic Medicine Year in Review: 2019

scientific article published on 05 December 2019

Genomic Medicine Year in Review: 2020

scientific article published on 01 December 2020

Germline genomic variants associated with childhood acute lymphoblastic leukemia

scientific journal article

Global implementation of genomic medicine: We are not alone

scientific article

HLA-DRB1*07:01 is associated with a higher risk of asparaginase allergies.

scientific article

Higher plasma asparaginase activity after intramuscular than intravenous Erwinia asparaginase

scientific article published on 23 April 2020

Host thiopurine methyltransferase status affects mercaptopurine antileukemic effectiveness in a murine model

scientific article

Hyaluronan synthase 3 variant and anthracycline-related cardiomyopathy: a report from the children's oncology group.

scientific article

Hypertension is a modifiable risk factor for osteonecrosis in acute lymphoblastic leukemia

scientific article published on 13 August 2019

Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome

scientific article published on 10 August 2010

Implementing Genomic Medicine in the Clinic

Implementing genomic medicine in the clinic: the future is here

scientific article published on 10 January 2013

Improved prognosis for older adolescents with acute lymphoblastic leukemia.

scientific article

In vivo response to methotrexate forecasts outcome of acute lymphoblastic leukemia and has a distinct gene expression profile

scientific article

Incidence of hip and knee osteonecrosis and their associations with bone mineral density in children with acute lymphoblastic leukaemia

scientific article published on 24 March 2020

Incorporation of pharmacogenomics into routine clinical practice: the Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline development process

scientific article

Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse

scientific article

Integrated analysis of pharmacologic, clinical and SNP microarray data using Projection Onto the Most Interesting Statistical Evidence with Adaptive Permutation Testing

scientific article

Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group

scientific article

Merging Electronic Health Record Data and Genomics for Cardiovascular Research: A Science Advisory From the American Heart Association

scientific article

Methotrexate-induced neurotoxicity and leukoencephalopathy in childhood acute lymphoblastic leukemia.

scientific article published on 18 February 2014

Modeling Mechanisms of In Vivo Variability in Methotrexate Accumulation and Folate Pathway Inhibition in Acute Lymphoblastic Leukemia Cells ⬇️

scientific article published on December 2, 2010

NUDT15 polymorphisms alter thiopurine metabolism and hematopoietic toxicity

scientific journal article

Network-based systems pharmacology reveals heterogeneity in LCK and BCL2 signaling and therapeutic sensitivity of T-cell acute lymphoblastic leukemia

scientific article published on 21 January 2021

Neuropathic pain during treatment for childhood acute lymphoblastic leukemia ⬇️

scientific article published on February 11, 2011

No evidence that G6PD deficiency affects the efficacy or safety of daunorubicin in acute lymphoblastic leukemia induction therapy

scientific article published on 07 March 2019

Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations

scientific journal article

Opportunities, resources, and techniques for implementing genomics in clinical care

scientific article published on 05 August 2019

Outcomes of children with BCR-ABL1–like acute lymphoblastic leukemia treated with risk-directed therapy based on the levels of minimal residual disease

scientific article

PG4KDS: a model for the clinical implementation of pre-emptive pharmacogenetics

scientific article

Palmar-plantar erythrodysesthesia syndrome following treatment with high-dose methotrexate or high-dose cytarabine

scientific article published on 11 May 2017

Pharmacogenetics of human carbonyl reductase 1 (CBR1) in livers from black and white donors

scientific article

Pharmacogenomics in the clinic

scientific article

Pharmacogenomics: challenges and opportunities

scientific article published on November 2006

Population PK/PD Model of Homocysteine Concentrations after High-Dose Methotrexate Treatment in Patients with Acute Lymphoblastic Leukemia ⬇️

scientific article published on September 25, 2012

Profiling chromatin accessibility in pediatric acute lymphoblastic leukemia identifies subtype-specific chromatin landscapes and gene regulatory networks

scientific article published on 13 March 2021

Prognostic impact of absolute lymphocyte counts at the end of remission induction in childhood acute lymphoblastic leukemia.

scientific article published on March 2013

Research directions in the clinical implementation of pharmacogenomics - An Overview of US programs and projects

scientific article published on 20 February 2018

Resumption of high‐dose methotrexate after acute kidney injury and glucarpidase use in pediatric oncology patients ⬇️

scientific article published on January 17, 2012

Serum ALT elevations in survivors of childhood cancer. A report from the St. Jude Lifetime Cohort Study

Severe hypertriglyceridaemia during therapy for childhood acute lymphoblastic leukaemia

scientific article

Shortening Infusion Time for High-Dose Methotrexate Alters Antileukemic Effects: A Randomized Prospective Clinical Trial ⬇️

scientific article published on March 28, 2011

Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells

scientific article

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia

scientific article

The Pharmacogenomics Research Network Translational Pharmacogenetics Program: overcoming challenges of real-world implementation

scientific article published on 19 March 2013

The changing burden of long-term health outcomes in survivors of childhood acute lymphoblastic leukaemia: a retrospective analysis of the St Jude Lifetime Cohort Study

scientific article published on 08 May 2019

Thiopurine pathway

scientific article

Topotecan combination chemotherapy in two new rodent models of retinoblastoma

scientific article published in October 2005

Treating childhood acute lymphoblastic leukemia without cranial irradiation

scientific article

Utility of early screening magnetic resonance imaging for extensive hip osteonecrosis in pediatric patients treated with glucocorticoids

scientific article

Voriconazole plasma concentrations in immunocompromised pediatric patients vary by CYP2C19 diplotypes.

scientific article

Whole-joint magnetic resonance imaging to assess osteonecrosis in pediatric patients with acute lymphoblastic lymphoma

scientific article published on 30 May 2020

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