List of works by Norman Klopp

A comparison of the accuracy of Illumina HumanHT-12 v3 Expression BeadChip and TaqMan qRT-PCR gene expression results in patient samples from the Tampere Vascular Study.

scientific article

A functional polymorphism within plasminogen activator urokinase (PLAU) is associated with Alzheimer's disease.

scientific article published on 6 July 2006

A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012

A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease

scientific article

A genome-wide association study identifies novel loci associated with circulating IGF-I and IGFBP-3

scientific article

A genome-wide association study identifies three loci associated with mean platelet volume

scientific article published on 24 December 2008

A genome-wide expression quantitative trait loci analysis of proprotein convertase subtilisin/kexin enzymes identifies a novel regulatory gene variant for FURIN expression and blood pressure

scientific article published on 27 March 2015

A meta-analysis of genome-wide association studies of the electrocardiographic early repolarization pattern

scientific article

A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease

scientific article

A novel GJA8 mutation causing a recessive triangular cataract.

scientific article published on 9 May 2008

A signal transducer and activator of transcription 6 haplotype influences the regulation of serum IgE levels

scientific article

Altered aggregation properties of mutant gamma-crystallins cause inherited cataract

scientific journal article

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

scientific article published on 31 May 2017

An integrated epigenetic and transcriptomic analysis reveals distinct tissue-specific patterns of DNA methylation associated with atopic dermatitis

scientific article published on 13 February 2014

Analysis of the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk

scientific article

Association between variations in the TLR4 gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL-cholesterol

scientific article

Association of NOD1 polymorphisms with atopic eczema and related phenotypes

scientific article

Association of a MTNR1B gene variant with fasting glucose and HOMA-B in children and adolescents with high BMI-SDS ⬇️

scientific article published on November 8, 2010

Association of the interleukin-1 receptor antagonist gene with asthma

scientific article published on 12 March 2004

Association study between genetic variants at the PIP5K2A gene locus and schizophrenia and bipolar affective disorder

article

Associations of IGF-1 gene variants and milk protein intake with IGF-I concentrations in infants at age 6 months - results from a randomized clinical trial

scientific article published on 22 June 2013

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Blood hsa-miR-122-5p and hsa-miR-885-5p levels associate with fatty liver and related lipoprotein metabolism-The Young Finns Study

scientific article published on 05 December 2016

Blood microRNA profile associates with the levels of serum lipids and metabolites associated with glucose metabolism and insulin resistance and pinpoints pathways underlying metabolic syndrome: the cardiovascular risk in Young Finns Study.

scientific article

CX3CR1 polymorphisms are associated with atopy but not asthma in German children

scientific article

CXCR1andCXCR2haplotypes synergistically modulate cystic fibrosis lung disease

scientific article published on 16 November 2011

Cohen syndrome diagnosis using whole genome arrays

scientific article published on 4 October 2010

Colorectal cancer and polymorphisms in DNA repair genes WRN , RMI1 and BLM

article

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Common variants at 12q15 and 12q24 are associated with infant head circumference

scientific article published on 15 April 2012

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

scientific article (publication date: May 2011)

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

scientific article

Common variation in the ADAM8 gene affects serum sADAM8 concentrations and the risk of myocardial infarction in two independent cohorts

scientific article

Congenital cataract and macular hypoplasia in humans associated with a de novo mutation in CRYAA and compound heterozygous mutations in P.

scientific article published on 2 February 2006

Corrigendum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scholarly article published in Nature Genetics

Crygf(Rop): the first mutation in the Crygf gene causing a unique radial lens opacity.

scientific article

DNA methylation of lipid-related genes affects blood lipid levels

scientific article published on 12 January 2015

DNA repair gene polymorphisms and risk of chronic atrophic gastritis: a case-control study

scientific article

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Deletion of Late Cornified Envelope 3B and 3C genes is not associated with atopic dermatitis.

scientific article published on 8 April 2010

Dense genotyping of candidate gene loci identifies variants associated with high-density lipoprotein cholesterol

scientific article published on 8 February 2011

Differentially expressed genes and canonical pathway expression in human atherosclerotic plaques - Tampere Vascular Study

scientific article published on 27 January 2017

Differentially expressed genes and canonical pathways in the ascending thoracic aortic aneurysm - The Tampere Vascular Study

scientific article published on 21 September 2017

Discovery and refinement of loci associated with lipid levels

scientific article

Dissection of genetic factors modulating fetal growth in cattle indicates a substantial role of the non-SMC condensin I complex, subunit G (NCAPG) gene

scientific article published on 31 August 2009

Do genetic factors protect for early onset lung cancer? A case control study before the age of 50 years

scientific article

Duffy antigen receptor for chemokines (Darc) polymorphism regulates circulating concentrations of monocyte chemoattractant protein-1 and other inflammatory mediators

scientific article

ERRATUM: Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

article by Matthew B. Lanktree et al published June 2012 in American Journal of Human Genetics

Early onset lung cancer, cigarette smoking and the SNP309 of the murine double minute-2 (MDM2) gene

scientific article

Erratum: Common variants at 12q15 and 12q24 are associated with infant head circumference

scholarly article published in Nature Genetics

Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

scholarly article published in Nature Genetics

Erratum: Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

article

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

scientific article

Establishment of a cohort for deep phenotyping of the immune response to influenza vaccination among elderly individuals recruited from the general population.

scientific article published on 10 April 2017

Estimating the single nucleotide polymorphism genotype misclassification from routine double measurements in a large epidemiologic sample

scientific article

Ethylnitrosourea-induced base pair substitution affects splicing of the mouse gammaE-crystallin encoding gene leading to the expression of a hybrid protein and to a cataract.

scientific article

Evidence for a relationship between genetic variants at the brain-derived neurotrophic factor (BDNF) locus and major depression

scientific article published in August 2005

Evidence for an association between genetic variants of the fatty acid desaturase 1 fatty acid desaturase 2 ( FADS1 FADS2) gene cluster and the fatty acid composition of erythrocyte membranes.

scientific article published on 15 May 2008

Expression and regulation of interferon-related development regulator-1 in cystic fibrosis neutrophils

scientific article published on 04 October 2012

Filaggrin mutations strongly predispose to early-onset and extrinsic atopic dermatitis

scientific article published on 09 November 2006

Filaggrin mutations, atopic eczema, hay fever, and asthma in children

scientific article

Functional characterization of promoter variants of the adiponectin gene complemented by epidemiological data

scientific article

Further genetic heterogeneity for autosomal dominant human sutural cataracts.

scientific article published in March 2003

G-Protein-coupled receptor polymorphisms are associated with asthma in a large German population

scientific article (publication date: 15 June 2005)

Gene-gene interaction between APOA5 and USF1: two candidate genes for the metabolic syndrome

scientific article

Genetic and allelic heterogeneity of Cryg mutations in eight distinct forms of dominant cataract in the mouse

scientific journal article

Genetic association between obstructive bronchitis and enzymes of oxidative stress

scientific article published on 26 June 2012

Genetic association study identifies HSPB7 as a risk gene for idiopathic dilated cardiomyopathy

scientific article

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease

scientific article (publication date: 15 November 2010)

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

scientific article

Genetic markers enhance coronary risk prediction in men: the MORGAM prospective cohorts

scientific article

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Genetic predisposition to an adverse lipid profile limits the improvement in total cholesterol in response to weight loss

scientific article published on 29 May 2013

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

scientific article

Genetic variants harbored in the forkhead box protein 3 locus increase hay fever risk.

scientific article

Genetic variants in Protocadherin-1, bronchial hyper-responsiveness, and asthma subphenotypes in German children.

scientific article

Genetic variants in the GATA3 gene are not associated with asthma and atopic diseases in German children.

scientific article published in April 2009

Genetic variation in the Toll-like receptor signaling pathway is associated with childhood asthma

scientific article published on 28 December 2012

Genetic variation in the prostate stem cell antigen gene and upper gastrointestinal cancer in white individuals

scientific article published on 9 November 2010

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

scientific article published on 26 June 2011

Genetic variations in polyunsaturated fatty acid metabolism--implications for child health?

scientific article published on 15 May 2012

Genome-Wide Association Study Pinpoints a New Functional Apolipoprotein B Variant Influencing Oxidized Low-Density Lipoprotein Levels But Not Cardiovascular Events

scholarly article by Kari-Matti Mäkelä et al published February 2013 in Circulation: Cardiovascular Genetics

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

scientific article published in February 2013

Genome-wide association analysis of high-density lipoprotein cholesterol in the population-based KORA study sheds new light on intergenic regions

scientific article published on October 2008

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

scientific article

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation

scientific article

Genome-wide association study identifies four genetic loci associated with thyroid volume and goiter risk ⬇️

scientific article

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

scientific article

Genome-wide association study in multiple human prion diseases suggests genetic risk factors additional to PRNP

scientific journal article

Genome-wide association study to identify common variants associated with brachial circumference: a meta-analysis of 14 cohorts

scientific article (publication date: 2012)

Genome-wide meta-analysis of common variant differences between men and women

scientific article published on 27 July 2012

Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations

scientific article published on 20 March 2009

Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus

scientific article

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article

Genotype-phenotype studies in bipolar disorder showing association between the DAOA/G30 locus and persecutory delusions: a first step toward a molecular genetic classification of psychiatric phenotypes.

scientific article published in November 2005

IL6 gene promoter polymorphisms and type 2 diabetes: joint analysis of individual participants' data from 21 studies

scientific article

IRF-1Gene Variations Influence IgE Regulation and Atopy

article

Identification of a novel, putative cataract-causing allele in CRYAA (G98R) in an Indian family

scientific article published on 12 July 2006

Identification of seven loci affecting mean telomere length and their association with disease

scientific article published on April 2013

ImmunoChip study implicates antigen presentation to T cells in narcolepsy

scientific article

Influence of FADS polymorphisms on tracking of serum glycerophospholipid fatty acid concentrations and percentage composition in children

scientific article

Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G>C with circulating glucose levels, interleukin-6 levels, and body mass index

scientific article

Kindlin 3 (FERMT3) is associated with unstable atherosclerotic plaques, anti-inflammatory type II macrophages and upregulation of beta-2 integrins in all major arterial beds

scientific article published on 13 July 2015

Lack of association between Toll-like receptor 2 and Toll-like receptor 4 polymorphisms and atopic eczema

scientific article published on 06 June 2006

Lack of support for a genetic association of the XBP1 promoter polymorphism with bipolar disorder in probands of European origin

scientific article published in August 2004

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

scientific article

Large-scale association analysis identifies new risk loci for coronary artery disease

scientific article published on 02 December 2012

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

scientific article

Loss-of-function mutations in the filaggrin gene and allergic contact sensitization to nickel

scientific article

Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations

scientific article

MMP-9 gene variants increase the risk for non-atopic asthma in children

scientific article

Macrophage migration inhibitory factor (MIF) and risk for coronary heart disease: Results from the MONICA/KORA Augsburg case-cohort study, 1984–2002

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

scientific article

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque

scientific article published on 11 September 2011

Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis

scientific article

Metabolite profiling reveals new insights into the regulation of serum urate in humans

scientific article published on 20 July 2013

Modulation of genetic associations with serum urate levels by body-mass-index in humans

scientific article

Molecular analysis of cataract families in India: new mutations in the CRYBB2 and GJA3 genes and rare polymorphisms ⬇️

scientific article published on September 10, 2010

Mutation analysis in a German family identified a new cataract-causing allele in the CRYBB2 gene.

scientific article published on 19 June 2007

N-acetyltransferase 2 phenotype, occupation, and bladder cancer risk: results from the EPIC cohort

scientific article published on 03 October 2013

NOD1 variation, immunoglobulin E and asthma.

scientific article published on 17 February 2005

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

scientific article published on 2 December 2012

New loci associated with kidney function and chronic kidney disease

scientific article

No association between genetic variants at the ASCT1 gene and schizophrenia or bipolar disorder in a German sample

article

No association between genetic variants at the GLYT2 gene and bipolar affective disorder and schizophrenia

scientific article

No association between genetic variants at the GRIN1 gene and bipolar disorder in a German sample.

scientific article published in October 2006

No association between the putative functional ZDHHC8 single nucleotide polymorphism rs175174 and schizophrenia in large European samples

scientific article

No association between the serine racemase gene (SRR) and bipolar disorder in a German case-control sample

scientific article published in April 2007

No association between the serine racemase gene (SRR) and schizophrenia in a German case-control sample.

scientific article published in April 2007

No association of two functional polymorphisms in human ALOX15 with myocardial infarction

scientific article

No evidence for an association between variants at the gamma-amino-n-butyric acid type A receptor beta2 locus and schizophrenia

scientific article published in February 2007

Novel associations for coronary artery disease derived from genome wide association studies are not associated with increased carotid intima-media thickness, suggesting they do not act via early atherosclerosis or vessel remodeling

scientific article published on 25 August 2011

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

PSEA: Phenotype Set Enrichment Analysis--a new method for analysis of multiple phenotypes

scientific article

Polycyclic aromatic hydrocarbons from diesel emissions exert proallergic effects in birch pollen allergic individuals through enhanced mediator release from basophils

scientific article published in April 2010

Polymorphisms in MUC1, MUC2, MUC5B and MUC6 genes are not associated with the risk of chronic atrophic gastritis

article

Polymorphisms in extracellular signal-regulated kinase family influence genetic susceptibility to asthma

scientific article published on 4 February 2013

Polymorphisms in inflammatory pathway genes and their association with colorectal cancer risk

scientific article published on December 2010

Polymorphisms related to ORMDL3 are associated with asthma susceptibility, alterations in transcriptional regulation of ORMDL3, and changes in TH2 cytokine levels.

scientific article published on 28 April 2015

Possible association between genetic variants at the GRIN1 gene and schizophrenia with lifetime history of depressive symptoms in a German sample.

scientific article published in October 2007

Predicting sudden cardiac death using common genetic risk variants for coronary artery disease

scientific article published on 23 April 2015

Quantifying the contribution of genetic variants for survival phenotypes

article

RANTES/CCL5 and risk for coronary events: results from the MONICA/KORA Augsburg case-cohort, Athero-Express and CARDIoGRAM studies

scientific article

RANTES/CCL5 gene polymorphisms, serum concentrations, and incident type 2 diabetes: results from the MONICA/KORA Augsburg case–cohort study, 1984–2002

article

Rationale, design and objectives of ARegPKD, a European ARPKD registry study

scientific article

SLC2A9 influences uric acid concentrations with pronounced sex-specific effects

scientific article

SNP-based analysis of genetic substructure in the German population.

scientific article

SNPs of the FADS gene cluster are associated with polyunsaturated fatty acids in a cohort of patients with cardiovascular disease

scientific article published on 5 March 2008

STAT6 as an asthma candidate gene: polymorphism-screening, association and haplotype analysis in a Caucasian sib-pair study.

scientific article published in March 2002

TBX21 gene variants increase childhood asthma risk in combination with HLX1 variants

scientific article

Talin and vinculin are downregulated in atherosclerotic plaque; Tampere Vascular Study

scientific article

Targeting 160 candidate genes for blood pressure regulation with a genome-wide genotyping array

scientific article

The GJA8 allele encoding CX50I247M is a rare polymorphism, not a cataract-causing mutation.

scientific article published on 14 September 2009

The KORA Eye Study: a population-based study on eye diseases in Southern Germany (KORA F4).

scientific article published on 29 September 2011

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

The role of polymorphisms in ADAM33, a disintegrin and metalloprotease 33, in childhood asthma and lung function in two German populations

scientific article

The role of variation at AβPP, PSEN1, PSEN2, and MAPT in late onset Alzheimer's disease

scientific article

Tobacco smoking leads to extensive genome-wide changes in DNA methylation

scientific article

Toll-like receptor heterodimer variants protect from childhood asthma

scientific article

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scientific article

Umbilical cord PUFA are determined by maternal and child fatty acid desaturase (FADS) genetic variants in the Avon Longitudinal Study of Parents and Children (ALSPAC).

scientific article published on 9 August 2012

Unifying candidate gene and GWAS Approaches in Asthma

scientific article

Upstream Transcription Factor 1 (USF1) allelic variants regulate lipoprotein metabolism in women and USF1 expression in atherosclerotic plaque

scientific article published on 11 April 2014

Variants of the FADS1 FADS2 gene cluster, blood levels of polyunsaturated fatty acids and eczema in children within the first 2 years of life

scientific article

Wnt signaling and Dupuytren's disease

scientific article

[Centralized biobanks: a basis for medical research].

scientific article published in February 2016

miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques in the Tampere Vascular Study

article published in 2011

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