List of works - Norman Klopp

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

scientific article

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

scientific article

Discovery and refinement of loci associated with lipid levels

scientific article

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

scientific article

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

scientific article

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

scientific article (publication date: May 2011)

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Large-scale association analysis identifies new risk loci for coronary artery disease

scientific article published on 02 December 2012

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

scientific article

New loci associated with kidney function and chronic kidney disease

scientific article

Identification of seven loci affecting mean telomere length and their association with disease

scientific article published on April 2013

A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease

scientific article

Tobacco smoking leads to extensive genome-wide changes in DNA methylation

scientific article

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

scientific article published in February 2013

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

scientific article

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

scientific article

SLC2A9 influences uric acid concentrations with pronounced sex-specific effects

scientific article

Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations

scientific article

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

scientific article

miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques in the Tampere Vascular Study

article published in 2011

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease

scientific article (publication date: 15 November 2010)

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

scientific article published on 26 June 2011

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

scientific article

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

scientific article published on 31 May 2017

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

scientific article published on 12 September 2016

Evidence for a relationship between genetic variants at the brain-derived neurotrophic factor (BDNF) locus and major depression

scientific article published in August 2005

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

scientific article published on 2 December 2012

Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis

scientific article

Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus

scientific article

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

NOD1 variation, immunoglobulin E and asthma

scientific article published on 17 February 2005

Filaggrin mutations, atopic eczema, hay fever, and asthma in children

scientific article

SNPs of the FADS gene cluster are associated with polyunsaturated fatty acids in a cohort of patients with cardiovascular disease

scientific article published on 5 March 2008

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque

scientific article published on 11 September 2011

Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations

scientific article published on 20 March 2009

Evidence for an association between genetic variants of the fatty acid desaturase 1 fatty acid desaturase 2 ( FADS1 FADS2) gene cluster and the fatty acid composition of erythrocyte membranes

scientific article published on 15 May 2008

Loss-of-function mutations in the filaggrin gene and allergic contact sensitization to nickel

scientific article

A genome-wide association search for type 2 diabetes genes in African Americans

scientific article published on 4 January 2012

Toll-like receptor heterodimer variants protect from childhood asthma

scientific article

Association of NOD1 polymorphisms with atopic eczema and related phenotypes

scientific article

ImmunoChip study implicates antigen presentation to T cells in narcolepsy

scientific article

Wnt signaling and Dupuytren's disease

scientific article

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

scientific article

Altered aggregation properties of mutant gamma-crystallins cause inherited cataract

scientific journal article

Common variants at 12q15 and 12q24 are associated with infant head circumference

scientific article published on 15 April 2012

SNP-based analysis of genetic substructure in the German population.

scientific article

DNA methylation of lipid-related genes affects blood lipid levels

scientific article published on 12 January 2015

A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease

scientific article

Genotype-phenotype studies in bipolar disorder showing association between the DAOA/G30 locus and persecutory delusions: a first step toward a molecular genetic classification of psychiatric phenotypes

scientific article published in November 2005

List of works by Norman Klopp

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

Discovery and refinement of loci associated with lipid levels

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease

Defining the role of common variation in the genomic and biological architecture of adult human height

Large-scale association analysis identifies new risk loci for coronary artery disease

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility

New loci associated with kidney function and chronic kidney disease

Identification of seven loci affecting mean telomere length and their association with disease

A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease

Tobacco smoking leads to extensive genome-wide changes in DNA methylation

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations

Common variants associated with plasma triglycerides and risk for coronary artery disease

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals

SLC2A9 influences uric acid concentrations with pronounced sex-specific effects

Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction

miR-21, miR-210, miR-34a, and miR-146a/b are up-regulated in human atherosclerotic plaques in the Tampere Vascular Study

Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci

An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans

The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals

Evidence for a relationship between genetic variants at the brain-derived neurotrophic factor (BDNF) locus and major depression

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis

Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

NOD1 variation, immunoglobulin E and asthma

Filaggrin mutations, atopic eczema, hay fever, and asthma in children

SNPs of the FADS gene cluster are associated with polyunsaturated fatty acids in a cohort of patients with cardiovascular disease

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque

Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations

Evidence for an association between genetic variants of the fatty acid desaturase 1 fatty acid desaturase 2 ( FADS1 FADS2) gene cluster and the fatty acid composition of erythrocyte membranes

Loss-of-function mutations in the filaggrin gene and allergic contact sensitization to nickel

A genome-wide association search for type 2 diabetes genes in African Americans

Toll-like receptor heterodimer variants protect from childhood asthma

Association of NOD1 polymorphisms with atopic eczema and related phenotypes

ImmunoChip study implicates antigen presentation to T cells in narcolepsy

Wnt signaling and Dupuytren's disease

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

Altered aggregation properties of mutant gamma-crystallins cause inherited cataract

Common variants at 12q15 and 12q24 are associated with infant head circumference

SNP-based analysis of genetic substructure in the German population.

DNA methylation of lipid-related genes affects blood lipid levels

A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease

Genotype-phenotype studies in bipolar disorder showing association between the DAOA/G30 locus and persecutory delusions: a first step toward a molecular genetic classification of psychiatric phenotypes