List of works by Peter W. Kalivas

A double-blind placebo-controlled trial of N-acetylcysteine in the treatment of cocaine dependence

scientific article

A single intra-PFC infusion of BDNF prevents cocaine-induced alterations in extracellular glutamate within the nucleus accumbens

scientific article published on March 2009

AKAP signaling in reinstated cocaine seeking revealed by iTRAQ proteomic analysis

scientific article

Accumbens nNOS Interneurons Regulate Cocaine Relapse

scientific article published on January 2017

Activation of orbital and medial prefrontal cortex by methylphenidate in cocaine-addicted subjects but not in controls: relevance to addiction.

scientific article

An open-label pilot trial of N-acetylcysteine and varenicline in adult cigarette smokers.

scientific article

Animal models and brain circuits in drug addiction

scientific article published on December 2006

Bipolar disorder and substance misuse: pathological and therapeutic implications of their comorbidity and cross-sensitisation

scientific article

Brain circuitry and the reinstatement of cocaine-seeking behavior

scientific article

Ceftriaxone normalizes nucleus accumbens synaptic transmission, glutamate transport, and export following cocaine self-administration and extinction training

scientific article

Ceftriaxone restores glutamate homeostasis and prevents relapse to cocaine seeking

scientific article

Chemogenetic Activation of an Extinction Neural Circuit Reduces Cue-Induced Reinstatement of Cocaine Seeking

scientific article published on 28 September 2016

Chronic N-acetylcysteine during abstinence or extinction after cocaine self-administration produces enduring reductions in drug seeking

scientific article

Cocaine activates Homer1 immediate early gene transcription in the mesocorticolimbic circuit: differential regulation by dopamine and glutamate signaling

scientific journal article

Cocaine and amphetamine-like psychostimulants: neurocircuitry and glutamate neuroplasticity

scientific article published on January 2007

Cocaine and sucrose rewards recruit different seeking ensembles in the nucleus accumbens core

scientific article published on 28 September 2020

Cocaine-induced adaptations in cellular redox balance contributes to enduring behavioral plasticity

scientific article

Cystine/glutamate exchange regulates metabotropic glutamate receptor presynaptic inhibition of excitatory transmission and vulnerability to cocaine seeking

scientific article

Drug Refraining and Seeking Potentiate Synapses on Distinct Populations of Accumbens Medium Spiny Neurons

scientific article published on 05 July 2018

Drug wanting: behavioral sensitization and relapse to drug-seeking behavior

scientific article

Extended access to cocaine self-administration enhances drug-primed reinstatement but not behavioral sensitization

scientific article

Extended methamphetamine self-administration in rats results in a selective reduction of dopamine transporter levels in the prefrontal cortex and dorsal striatum not accompanied by marked monoaminergic depletion

scientific article published on 31 July 2009

Extinction circuits for fear and addiction overlap in prefrontal cortex

scientific article (publication date: May 2009)

Extinction training after cocaine self-administration induces glutamatergic plasticity to inhibit cocaine seeking

scientific article

Glutamate and reinstatement

scientific article published on 20 January 2009

Glutamate release in the nucleus accumbens core is necessary for heroin seeking.

scientific article

Glutamate systems in cocaine addiction

scientific article published on February 2004

Glutamate transmission in addiction

scientific article published on 16 July 2008

Glutamate transporter GLT-1 mediates N-acetylcysteine inhibition of cocaine reinstatement

scientific article published on 25 February 2014

Group II metabotropic glutamate receptors (mGlu2/3) in drug addiction

scientific article

Group II metabotropic glutamate receptors modulate extracellular glutamate in the nucleus accumbens

scientific article

Harnessing neuroplasticity for clinical applications ⬇️

scientific article

Heroin relapse requires long-term potentiation-like plasticity mediated by NMDA2b-containing receptors.

scientific article published on 14 November 2011

Homer proteins regulate sensitivity to cocaine

scientific journal article

Infralimbic prefrontal cortex is responsible for inhibiting cocaine seeking in extinguished rats

scientific article published on June 2008

Long-term neuroadaptations produced by withdrawal from repeated cocaine treatment: role of dopaminergic receptors in modulating cortical excitability

scientific article

Loss of Plasticity in the D2-Accumbens Pallidal Pathway Promotes Cocaine Seeking.

scientific article published on January 2017

Matrix-assisted laser desorption/ionization tissue profiling of secretoneurin in the nucleus accumbens shell from cocaine-sensitized rats

scientific article

Modafinil attenuates reinstatement of cocaine seeking: role for cystine-glutamate exchange and metabotropic glutamate receptors

scientific article published on 27 September 2012

N-Acetylcysteine treatment during acute stress prevents stress-induced augmentation of addictive drug use and relapse

scientific article published on 07 July 2019

NAC1 regulates the recruitment of the proteasome complex into dendritic spines

scientific article published in August 2007

Neural circuit competition in cocaine-seeking: roles of the infralimbic cortex and nucleus accumbens shell

scientific article

New vistas on cannabis use disorder

scientific article

Non-Opioid Treatments for Opioid Use Disorder: Rationales and Data to Date

scientific article published on 10 August 2020

Nrf2 gene deletion fails to alter psychostimulant-induced behavior or neurotoxicity.

scientific article published on 17 November 2006

Optogenetic inhibition of cocaine seeking in rats

scientific article

Optogenetic inhibition of cortical afferents in the nucleus accumbens simultaneously prevents cue-induced transient synaptic potentiation and cocaine-seeking behavior

scientific article published on 7 February 2015

Potential role of N-acetylcysteine in the management of substance use disorders

scientific article

Rapid, transient synaptic plasticity in addiction

scientific article

Reduced LTP and LTD in prefrontal cortex synapses in the nucleus accumbens after heroin self-administration

scientific article

Relapse-associated Transient Synaptic Potentiation Requires Integrin-mediated Activation of Focal Adhesion Kinase and Cofilin in D1-expressing Neurons

scientific article published on 13 October 2020

Requirement for the POZ/BTB protein NAC1 in acute but not chronic psychomotor stimulant response

scientific article

Restoration of Kv7 Channel-Mediated Inhibition Reduces Cued-Reinstatement of Cocaine Seeking.

scientific article published on 10 April 2018

Reversing cocaine-induced synaptic potentiation provides enduring protection from relapse.

scientific article

Role of mGluR5 neurotransmission in reinstated cocaine-seeking

scientific article

Role of the prefrontal cortex and nucleus accumbens in reinstating methamphetamine seeking

scientific article

Safety and tolerability of N-acetylcysteine in cocaine-dependent individuals.

scientific article

Stress-induced sensitization to cocaine: actin cytoskeleton remodeling within mesocorticolimbic nuclei

scientific journal article

Supplementing high-density SNP microarrays for additional coverage of disease-related genes: addiction as a paradigm

scientific article

Synaptic plasticity mediating cocaine relapse requires matrix metalloproteinases.

scientific article

The cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities. ⬇️

scientific article

The effect of N-acetylcysteine in the nucleus accumbens on neurotransmission and relapse to cocaine

scientific article

The infralimbic cortex regulates the consolidation of extinction after cocaine self-administration

scientific article

The loss of NMDAR-dependent LTD following cannabinoid self-administration is restored by positive allosteric modulation of CB1 receptors

scientific article published on 16 November 2019

The origin and neuronal function of in vivo nonsynaptic glutamate.

scientific article

The role of cystine-glutamate exchange in nicotine dependence in rats and humans

scientific journal article

The temporal sequence of changes in gene expression by drugs of abuse

scientific article

Transient synaptic potentiation in nucleus accumbens shell during refraining from cocaine seeking

scientific article published on 06 May 2019

Using glutamate homeostasis as a target for treating addictive disorders

scientific article

Ventral Pallidum Is the Primary Target for Accumbens D1 Projections Driving Cocaine Seeking

scientific article published on 08 January 2019

α2δ-1 signaling in nucleus accumbens is necessary for cocaine-induced relapse.

scientific article

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