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List of works by Cornelis A. M. de Haan

A field-proven yeast two-hybrid protocol used to identify coronavirus-host protein-protein interactions

scientific article published on January 2015

A protective and safe intranasal RSV vaccine based on a recombinant prefusion-like form of the F protein bound to bacterium-like particles

scientific article

A single immunization with soluble recombinant trimeric hemagglutinin protects chickens against highly pathogenic avian influenza virus H5N1

scientific article (publication date: 14 May 2010)

ATP1A1-mediated Src signaling inhibits coronavirus entry into host cells

scientific article

Adaptation of novel H7N9 influenza A virus to human receptors

scientific article published on 28 October 2013

An autophagy-independent role for LC3 in equine arteritis virus replication

scientific article published on 26 November 2012

An siRNA screen for ATG protein depletion reveals the extent of the unconventional functions of the autophagy proteome in virus replication.

scientific article published on August 2016

Antiviral Activity of Chicken Cathelicidin B1 Against Influenza A Virus

scientific article published on 19 March 2020

Are nidoviruses hijacking the autophagy machinery?

scientific article

Autophagy-independent LC3 function in vesicular traffic.

scientific article published on 11 October 2010

Biogenesis and dynamics of the coronavirus replicative structures

scientific article

Bovine IgG Prevents Experimental Infection With RSV and Facilitates Human T Cell Responses to RSV

scientific article published on 06 August 2020

Breast Milk Prefusion F Immunoglobulin G as a Correlate of Protection Against Respiratory Syncytial Virus Acute Respiratory Illness.

scientific article

CD200 receptor controls sex-specific TLR7 responses to viral infection

scientific article

Characteristics of RSV-Specific Maternal Antibodies in Plasma of Hospitalized, Acute RSV Patients under Three Months of Age

scientific article

Characterization of Epitope-Specific Anti-Respiratory Syncytial Virus (Anti-RSV) Antibody Responses after Natural Infection and after Vaccination with Formalin-Inactivated RSV

scientific article published on 20 April 2016

Cleavage inhibition of the murine coronavirus spike protein by a furin-like enzyme affects cell-cell but not virus-cell fusion

scientific article

Competition between influenza A virus genome segments

scientific article

Cooperative involvement of the S1 and S2 subunits of the murine coronavirus spike protein in receptor binding and extended host range.

scientific article

Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner.

scientific article

Coronavirus escape from heptad repeat 2 (HR2)-derived peptide entry inhibition as a result of mutations in the HR1 domain of the spike fusion protein

scientific article published on 12 December 2007

Coronavirus nucleocapsid proteins assemble constitutively in high molecular oligomers

scientific article published on 18 July 2017

Coronavirus particle assembly: primary structure requirements of the membrane protein

scientific article

Coronavirus spike glycoprotein, extended at the carboxy terminus with green fluorescent protein, is assembly competent

scientific article published on July 2004

Coronaviruses Hijack the LC3-I-positive EDEMosomes, ER-derived vesicles exporting short-lived ERAD regulators, for replication

scientific article

Coronaviruses as vectors: position dependence of foreign gene expression

scientific article published on November 2003

Coronaviruses as vectors: stability of foreign gene expression

scientific article published on October 2005

Coronaviruses maintain viability despite dramatic rearrangements of the strictly conserved genome organization

scientific article

Coxsackievirus mutants that can bypass host factor PI4KIIIβ and the need for high levels of PI4P lipids for replication

scientific article

Cross-Protective Immune Responses Induced by Sequential Influenza Virus Infection and by Sequential Vaccination With Inactivated Influenza Vaccines

article

Cyclooxygenase activity is important for efficient replication of mouse hepatitis virus at an early stage of infection.

scientific article

Development and Standardization of a High-Throughput Multiplex Immunoassay for the Simultaneous Quantification of Specific Antibodies to Five Respiratory Syncytial Virus Proteins

article

Display of the human mucinome with defined O-glycans by gene engineered cells

scientific article

Dissecting virus entry: replication-independent analysis of virus binding, internalization, and penetration using minimal complementation of β-galactosidase

scientific article

Dissection of the influenza A virus endocytic routes reveals macropinocytosis as an alternative entry pathway

scientific article

Dynamics of coronavirus replication-transcription complexes.

scientific article

Enhanced Inhibition of Influenza A Virus Adhesion by Di- and Trivalent Hemagglutinin Inhibitors

scientific article published on 28 June 2019

Enterocytes, fibroblasts and myeloid cells synergize in anti-bacterial and anti-viral pathways with IL22 as the central cytokine

scientific article published on 27 May 2021

Enterovirus D68 receptor requirements unveiled by haploid genetics.

scientific article published on 19 January 2016

Evolution of the hemagglutinin protein of the new pandemic H1N1 influenza virus: maintaining optimal receptor binding by compensatory substitutions.

scientific article

First-in-human administration of a live-attenuated RSV vaccine lacking the G-protein assessing safety, tolerability, shedding and immunogenicity: a randomized controlled trial

scientific article published on 25 July 2020

Genetic versus antigenic differences among highly pathogenic H5N1 avian influenza A viruses: Consequences for vaccine strain selection

scientific article published on 27 January 2017

Glycan-dependent immunogenicity of recombinant soluble trimeric hemagglutinin

scientific article

Glycosylation Characterization of an Influenza H5N7 Hemagglutinin Series with Engineered Glycosylation Patterns: Implications for Structure-Function Relationships.

scientific article published on 5 December 2016

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Hemagglutinin Receptor Specificity and Structural Analyses of Respiratory Droplet-Transmissible H5N1 Viruses

scientific article

Highly Pathogenic Influenza A(H5Nx) Viruses with Altered H5 Receptor-Binding Specificity

scientific article published on 15 February 2017

Host tissue and glycan binding specificities of avian viral attachment proteins using novel avian tissue microarrays

scientific article published on 2 June 2015

Hosting the severe acute respiratory syndrome coronavirus: specific cell factors required for infection

scientific article published on 27 June 2006

Human-type sialic acid receptors contribute to avian influenza A virus binding and entry by hetero-multivalent interactions

scientific article published on 13 July 2022

Identification and characterization of a proteolytically primed form of the murine coronavirus spike proteins after fusion with the target cell.

scientific article

Identification of Residues That Affect Oligomerization and/or Enzymatic Activity of Influenza Virus H5N1 Neuraminidase Proteins

scientific article published on 10 August 2016

Identification of host factors involved in coronavirus replication by quantitative proteomics analysis

scientific article published on 6 December 2010

Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein.

scientific article published on 18 September 2017

Impaired Antibody-mediated Protection and Defective IgA B-Cell Memory in Experimental Infection of Adults with Respiratory Syncytial Virus

scientific article published on May 2015

Improved microarray gene expression profiling of virus-infected cells after removal of viral RNA

scientific article

In Vitro Enhancement of Respiratory Syncytial Virus Infection by Maternal Antibodies Does Not Explain Disease Severity in Infants.

scientific article published on 09 August 2017

In silico structure-based design and synthesis of novel anti-RSV compounds

scientific article published on 8 August 2015

Influenza A Virus Hemagglutinin-Neuraminidase-Receptor Balance: Preserving Virus Motility

scientific article published on 16 October 2019

Influenza A virus entry into cells lacking sialylated N-glycans

scientific article

Inhibition of the ubiquitin-proteasome system affects influenza A virus infection at a postfusion step

scientific article

Kinetic analysis of the influenza A virus HA/NA balance reveals contribution of NA to virus-receptor binding and NA-dependent rolling on receptor-containing surfaces

scientific article published on 13 August 2018

Manipulation of the coronavirus genome using targeted RNA recombination with interspecies chimeric coronaviruses

scientific article published in January 2008

Mapping of the coronavirus membrane protein domains involved in interaction with the spike protein

scientific article published on September 1999

Membrane rearrangements mediated by coronavirus nonstructural proteins 3 and 4.

scientific article

Mobility and interactions of coronavirus nonstructural protein 4.

scientific article

Molecular interactions in the assembly of coronaviruses

scientific article published on 01 January 2005

Mouse Hepatitis Coronavirus RNA Replication Depends on GBF1-Mediated ARF1 Activation

scientific article (publication date: 13 June 2008)

Mouse hepatitis coronavirus replication induces host translational shutoff and mRNA decay, with concomitant formation of stress granules and processing bodies

scientific article published on 08 May 2007

Murine coronavirus with an extended host range uses heparan sulfate as an entry receptor

scientific article published on November 2005

Mutation of the Second Sialic Acid-Binding Site, Resulting in Reduced Neuraminidase Activity, Preceded the Emergence of H7N9 Influenza A Virus

scientific article

Mutation of the second sialic acid-binding site of influenza A virus neuraminidase drives compensatory mutations in hemagglutinin

scientific article published on 27 August 2020

Non-invasive imaging of mouse hepatitis coronavirus infection reveals determinants of viral replication and spread in vivo.

scientific article published on 10 February 2009

Nucleocapsid Protein Recruitment to Replication-Transcription Complexes Plays a Crucial Role in Coronaviral Life Cycle

scientific article published on 31 January 2020

Only two residues are responsible for the dramatic difference in receptor binding between swine and new pandemic H1 hemagglutinin

scientific article

Oseltamivir analogues bearing N-substituted guanidines as potent neuraminidase inhibitors

scientific article published on 31 March 2014

Passive inhalation of dry powder influenza vaccine formulations completely protects chickens against H5N1 lethal viral challenge

scientific article published on 09 October 2018

Protective efficacy of Newcastle disease virus expressing soluble trimeric hemagglutinin against highly pathogenic H5N1 influenza in chickens and mice

scientific article

Qualitative and quantitative ultrastructural analysis of the membrane rearrangements induced by coronavirus

scientific article

Quantitative proteomic identification of host factors involved in the Salmonella typhimurium infection cycle

scientific article

RSV neutralization by palivizumab, but not by monoclonal antibodies targeting other epitopes, is augmented by Fc gamma receptors.

scientific article published on 13 May 2016

Rapid Emergence of Highly Pathogenic Avian Influenza Subtypes from a Subtype H5N1 Hemagglutinin Variant

scientific article published on May 2015

Recombinant Soluble Respiratory Syncytial Virus F Protein That Lacks Heptad Repeat B, Contains a GCN4 Trimerization Motif and Is Not Cleaved Displays Prefusion-Like Characteristics.

scientific article published on 24 June 2015

Recombinant soluble, multimeric HA and NA exhibit distinctive types of protection against pandemic swine-origin 2009 A(H1N1) influenza virus infection in ferrets

scientific article

Role of Endocytosis and Low pH in Murine Hepatitis Virus Strain A59 Cell Entry

scientific article (publication date: October 2007)

Role of enhanced receptor engagement in the evolution of a pandemic acute hemorrhagic conjunctivitis virus ⬇️

scientific article published on 28 December 2017

Role of the SEL1L:LC3-I complex as an ERAD tuning receptor in the mammalian ER.

scientific article published on 24 May 2012

Second sialic acid-binding site of influenza A virus neuraminidase: Binding receptors for efficient release

scientific article published on 14 December 2020

Serological screening of influenza A virus antibodies in cats and dogs indicates frequent infection with different subtypes

scientific article published on 02 September 2020

Single-cell analysis of population context advances RNAi screening at multiple levels

scientific article

Spike protein assembly into the coronavirion: exploring the limits of its sequence requirements

scientific article

Studying the dynamics of coronavirus replicative structures

scientific article

Substitutions T200A and E227A in the hemagglutinin of pandemic 2009 influenza A virus increase lethality but decrease transmission

scientific article

Substrate Binding by the Second Sialic Acid-Binding Site of Influenza A Virus N1 Neuraminidase Contributes to Enzymatic Activity

scholarly article by Wenjuan Du published in October 2018

The 29-nucleotide deletion present in human but not in animal severe acute respiratory syndrome coronaviruses disrupts the functional expression of open reading frame 8.

scientific article

The 2nd sialic acid-binding site of influenza A virus neuraminidase is an important determinant of the hemagglutinin-neuraminidase-receptor balance.

scientific article published on 10 June 2019

The Coronavirus Spike Protein Is a Class I Virus Fusion Protein: Structural and Functional Characterization of the Fusion Core Complex

scientific article

The coronavirus nucleocapsid protein is dynamically associated with the replication-transcription complexes

scientific article

The glycosylation status of the murine hepatitis coronavirus M protein affects the interferogenic capacity of the virus in vitro and its ability to replicate in the liver but not the brain

scientific article published in August 2003

The group-specific murine coronavirus genes are not essential, but their deletion, by reverse genetics, is attenuating in the natural host

scientific article published on 01 April 2002

The influenza A virus hemagglutinin glycosylation state affects receptor-binding specificity

scientific article

The proteasome inhibitor Velcade enhances rather than reduces disease in mouse hepatitis coronavirus-infected mice.

scientific article published on 19 May 2010

The ubiquitin-proteasome system plays an important role during various stages of the coronavirus infection cycle

scientific article

Three mutations switch H7N9 influenza to human-type receptor specificity.

scientific article

Topology and Membrane Anchoring of the Coronavirus Replication Complex: Not All Hydrophobic Domains of nsp3 and nsp6 Are Membrane Spanning

scientific article (publication date: December 2008)

Type I interferon receptor-independent and -dependent host transcriptional responses to mouse hepatitis coronavirus infection in vivo

scientific article

Unconventional use of LC3 by coronaviruses through the alleged subversion of the ERAD tuning pathway

scientific article

Vaccinia virus-induced microtubule-dependent cellular rearrangements

scientific article published on March 2006

Vaccinia-virus-induced cellular contractility facilitates the subcellular localization of the viral replication sites

scientific article published on 10 August 2006

Varying Viral Replication and Disease Profiles of H2N2 Influenza in Ferrets Is Associated with Virus Isolate and Inoculation Route

scientific article published on 11 July 2022

Visualizing coronavirus RNA synthesis in time by using click chemistry

scientific article

β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway

scientific article published on 27 October 2020

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