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List of works by Arthur Wilde

'Brugada ECG' elicited by imipramine overdose

scientific article published on September 2004

'Cardiac Radioablation - a Systematic Review'

scientific article published on 20 March 2020

2019 HRS expert consensus statement on evaluation, risk stratification, and management of arrhythmogenic cardiomyopathy

scientific article published on 09 May 2019

2019 HRS expert consensus statement on evaluation, risk stratification, and management of arrhythmogenic cardiomyopathy: Executive summary

scientific article published on 01 November 2019

2020 APHRS/HRS Expert Consensus Statement on the Investigation of Decedents with Sudden Unexplained Death and Patients with Sudden Cardiac Arrest, and of Their Families

scientific article published on 13 October 2020

50 Years of Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) - Time to Explore the Dark Side of the Moon

scientific article published on 06 December 2019

A Comprehensive Evaluation of the Genetic Architecture of Sudden Cardiac Arrest

A Novel Familial Cardiac Arrhythmia Syndrome with Widespread ST-Segment Depression

scientific article published on 01 November 2018

A Potential Diagnostic Approach for Foetal Long-QT Syndrome, Developed and Validated in Children

A calcium sensor in the sodium channel modulates cardiac excitability

scientific article

A cardiac sodium channel mutation cosegregates with a rare connexin40 genotype in familial atrial standstill

scientific article published in January 2003

A common arrhythmia, not so common at an old age.

scientific article published on February 2014

A common arrhythmia, not so common at an old age.

scientific article

A common co-morbidity modulates disease expression and treatment efficacy in inherited cardiac sodium channelopathy

scientific article published on 01 August 2018

A common polymorphism in KCNH2 (HERG) hastens cardiac repolarization

scientific article published on 01 July 2003

A complex double deletion in LMNA underlies progressive cardiac conduction disease, atrial arrhythmias, and sudden death.

scientific article

A connexin40 mutation associated with a malignant variant of progressive familial heart block type I

scientific article

A fainting lady with some extrasystoles

scientific article published on February 2004

A family with Andersen-Tawil syndrome and dilated cardiomyopathy

scientific article published on 21 July 2006

A gain-of-function TBX5 mutation is associated with atypical Holt-Oram syndrome and paroxysmal atrial fibrillation

scientific article published on 01 May 2008

A highly specific biomarker for Brugada syndrome. Also too good to be true?

scientific article published on 19 June 2020

A large candidate gene survey identifies the KCNE1 D85N polymorphism as a possible modulator of drug-induced torsades de pointes

scientific article published on 18 November 2011

A large family characterised by nocturnal sudden death

scientific article

A long RP supraventricular tachycardia

scientific article published on June 2003

A mutation in CALM1 encoding calmodulin in familial idiopathic ventricular fibrillation in childhood and adolescence

scientific article published on 25 September 2013

A mutation in the human cardiac sodium channel (E161K) contributes to sick sinus syndrome, conduction disease and Brugada syndrome in two families

scientific article published in April 2005

A narrow QRS complex tachycardia sensitive to Isoptin

scientific article published on August 2006

A new prediction model for ventricular arrhythmias in arrhythmogenic right ventricular cardiomyopathy.

scientific article

A novel LQT3 mutation implicates the human cardiac sodium channel domain IVS6 in inactivation kinetics

scientific article published in March 2003

A novel alpha-tropomyosin mutation associates with dilated and non-compaction cardiomyopathy and diminishes actin binding

scientific article published on 09 November 2012

A novel autosomal dominant condition consisting of congenital heart defects and low atrial rhythm maps to chromosome 9q ⬇️

scientific article published on March 9, 2011

A novel early onset lethal form of catecholaminergic polymorphic ventricular tachycardia maps to chromosome 7p14-p22

A novel tool to evaluate the implant position and predict defibrillation success of the subcutaneous implantable defibrillator: the PRAETORIAN score

scientific article published on 04 October 2018

A pre-excited wide QRS complex: is that all there is?

scientific article published on March 2006

ABSTRACTS

scholarly article

Absence of calsequestrin 2 causes severe forms of catecholaminergic polymorphic ventricular tachycardia

scientific article published on 01 October 2002

Accelerated sinus rhythm prevents catecholaminergic polymorphic ventricular tachycardia in mice and in patients.

scientific article published on 7 January 2013

Accurate electrocardiographic assessment of the QT interval: teach the tangent

scientific article published on 01 April 2008

Activated human platelet products induce proarrhythmic effects in ventricular myocytes

scientific article published on 30 May 2011

Activation delay and VT parameters in arrhythmogenic right ventricular dysplasia/cardiomyopathy: toward improvement of diagnostic ECG criteria

scientific article published on 26 March 2008

Active cascade screening in primary inherited arrhythmia syndromes: does it lead to prophylactic treatment?

scientific article published in June 2010

Acute and 3-Month Performance of a Communicating Leadless Antitachycardia Pacemaker and Subcutaneous Implantable Defibrillator

scientific article published on 31 May 2017

Age of First Arrhythmic Event in Brugada Syndrome: Data From the SABRUS (Survey on Arrhythmic Events in Brugada Syndrome) in 678 Patients

scientific article published on 18 December 2017

Aging in Brugada Syndrome: What About Risks?

scientific article published on 03 August 2016

An International External Validation Study of the 2014 European Society of Cardiology Guideline on Sudden Cardiac Death Prevention in Hypertrophic Cardiomyopathy (Evidence from HCM).

scientific article

An International Multi-Center Evaluation of Inheritance Patterns, Arrhythmic Risks, and Underlying Mechanisms of CASQ2- Catecholaminergic Polymorphic Ventricular Tachycardia

scientific article published on 22 July 2020

An International Multicenter Evaluation of Type 5 Long QT Syndrome: A Low Penetrant Primary Arrhythmic Condition

scientific article published on 16 January 2020

An International, Multicentered, Evidence-Based Reappraisal of Genes Reported to Cause Congenital Long QT Syndrome

scientific article published on 27 January 2020

An atypical arrhythmia

An atypical arrhythmia.

scientific article published on 9 April 2013

An extended family suddenly confronted with a life-threatening hereditary arrhythmia

scientific article published on September 2005

An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing

scientific article

An intronic mutation leading to incomplete skipping of exon-2 in KCNQ1 rescues hearing in Jervell and Lange-Nielsen syndrome

scientific article published in October 2008

An old lady with chest pain

scientific article published in April 2006

An unexpected ECG finding

Analysis for Genetic Modifiers of Disease Severity in Patients With Long-QT Syndrome Type 2

scientific article published on 3 March 2015

And what about the ECG?

scientific article published on September 2006

Andersen-Tawil syndrome, scarier for the doctor than for the patient? Who, when, and how to treat

scientific article

Anti-arrhythmic potential of the late sodium current inhibitor GS-458967 in murine Scn5a-1798insD+/- and human SCN5A-1795insD+/- iPSC-derived cardiomyocytes.

scientific article

Antiarrhythmic drugs, patients, and the pharmaceutical industry: value for patients, physicians, pharmacists or shareholders?

scientific article published on January 2007

Are women with severely symptomatic brugada syndrome different from men?

scientific article

Arrhythmias in Brugada syndrome: changing throughout day and season?

scientific article published on 03 September 2008

Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy According to Revised 2010 Task Force Criteria With Inclusion of Non-Desmosomal Phospholamban Mutation Carriers ⬇️

scientific article published on July 19, 2013

Arrhythmogenic right ventricular cardiomyopathy due to a novel plakophilin 2 mutation: wide spectrum of disease in mutation carriers within a family

scientific article

Arrhythmogenic right ventricular cardiomyopathy: asymptomatic to life threatening as illustrated by the cases of two sisters

scientific article published in January 2007

Arrhythmogenic right ventricular dysplasia/cardiomyopathy diagnostic task force criteria: impact of new task force criteria

scientific article published on 9 March 2010

Arrhythmogenic right ventricular dysplasia/cardiomyopathy: pathogenic desmosome mutations in index-patients predict outcome of family screening: Dutch arrhythmogenic right ventricular dysplasia/cardiomyopathy genotype-phenotype follow-up study

scientific article (publication date: 14 June 2011)

Assessment and Validation of a Phenotype-Enhanced Variant Classification Framework to Promote or Demote RYR2 Missense Variants of Uncertain Significance

scientific article published on 01 May 2019

Assessment of the Extravascular Implantable Defibrillator: Feasibility of Substernal Ventricular Pacing

scientific article published on 04 April 2017

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events

scientific article published on 21 March 2019

Asymmetry of parental origin in long QT syndrome: preferential maternal transmission of KCNQ1 variants linked to channel dysfunction.

scientific article published on 16 December 2015

Athletes with channelopathy may be eligible to play

scientific article published on 6 February 2018

Atlas of the clinical genetics of human dilated cardiomyopathy

scientific article (publication date: 7 May 2015)

Autosomal recessive long QT syndrome, type 1 in eight families from Saudi Arabia.

scientific article published on 21 June 2017

Baseline NT-ProBNP level predicts success of cardioversion of atrial fibrillation with flecainide

scientific article

Beta-blockers in the treatment of congenital long QT syndrome: is one beta-blocker superior to another?

scientific article published on 01 September 2014

Biomarkers in inherited arrhythmias: necessity for validation and collaboration

scientific article published on 17 November 2020

Bringing home the bacon? The next step in cardiac sodium channelopathies

scientific article

Brugada Syndrome

article from 2012

Brugada Syndrome and the Subcutaneous Implantable Cardioverter-Defibrillator

scientific article published on 01 August 2016

Brugada Syndrome: Overview

Brugada phenocopy: new terminology and proposed classification.

scientific article published on 13 August 2012

Brugada syndrome and the use of anesthetics.

scientific article published on 15 June 2006

Brugada syndrome: in search of a genotype-phenotype relationship

scientific article published on 01 September 2002

Brugada syndrome: report of the second consensus conference.

scientific article

Brugada syndrome: report of the second consensus conference: endorsed by the Heart Rhythm Society and the European Heart Rhythm Association.

scientific article

COMPANION - a friend indeed

scientific article published on September 2003

COVID-19 vaccination in patients with long QT syndrome

scientific article published in 2022

Calmodulin mutations and life-threatening cardiac arrhythmias: insights from the International Calmodulinopathy Registry

scientific article published on 01 September 2019

Can parents adjust to the idea that their child is at risk for a sudden death?: Psychological impact of risk for long QT syndrome

scientific article published on 01 October 2005

Cardiac abnormalities in a follow-up study on carriers of Duchenne and Becker muscular dystrophy ⬇️

scientific article published on June 22, 2011

Cardiac dysfunction after aneurysmal subarachnoid hemorrhage: relationship with outcome.

scientific article

Cardiac involvement in Dutch patients with sarcoglycanopathy: a cross-sectional cohort and follow-up study

scientific article published in December 2014

Cardiac ion channels in health and disease

scientific article published on 05 August 2009

Cardiac resynchronization improves microcirculation

scientific article published in March 2007

Cardiac sodium channel overlap syndromes: different faces of SCN5A mutations

scientific article published on April 2008

Cardiac sodium channels and inherited electrophysiologic disorders: a pharmacogenetic overview

scientific article published on March 2008

Cardiogenetic counselling in a non-university hospital

scientific article

Cardiogenetics, 25 years a growing subspecialism

scientific article published on 01 August 2020

Cardiomyocytes derived from pluripotent stem cells recapitulate electrophysiological characteristics of an overlap syndrome of cardiac sodium channel disease

scientific article published on 30 May 2012

Cardiorenal axis and arrhythmias: Will renal sympathetic denervation provide additive value to the therapeutic arsenal?

scientific article

Cardiovascular Safety of Degarelix: Results From a 12-Month, Comparative, Randomized, Open Label, Parallel Group Phase III Trial in Patients With Prostate Cancer ⬇️

scientific article published on October 16, 2010

Caring for the pregnant woman with an inherited arrhythmia syndrome

scientific article published on 07 August 2019

Carotid sinus clues

scientific article published on April 2003

Carriers of the hypertrophic cardiomyopathy MYBPC3 mutation are characterized by reduced myocardial efficiency in the absence of hypertrophy and microvascular dysfunction

scientific article

Cases in Precision Medicine: Genetic Assessment After a Sudden Cardiac Death in the Family

scientific article published on 14 May 2019

Catecholaminergic polymorphic ventricular tachycardia: disease with different faces

scientific article published on 01 June 2015

Catecholaminergic polymorphic ventricular tachycardia: from bench to bedside ⬇️

scientific article published on 06 February 2013

Catecholaminergic polymorphic ventricular tachycardia: important messages from case reports ⬇️

scientific article published on September 17, 2010

Catecholaminergic polymorphic ventricular tachycardia; possible diagnosis in cases of syncope and sudden death of family members

scientific article published in January 2015

Catheter ablation in highly symptomatic Brugada patients: a Dutch case series

scientific article published on 02 September 2019

Challenging the unifying pathophysiological concept of J-wave syndromes

scientific article

Channelopathies as Causes of Sudden Cardiac Death

scientific article published in December 2017

Channelopathies in children and adults

scientific article published on February 2008

Channelopathies, genetic testing and risk stratification

scientific article published on 18 March 2017

Characterization and Management of Arrhythmic Events in Young Patients With Brugada Syndrome

scientific article published on 01 April 2019

Characterization of SEMA3A-encoded semaphorin as a naturally occurring Kv4.3 protein inhibitor and its contribution to Brugada syndrome

scientific article published on 24 June 2014

Characterization of a novel SCN5A mutation associated with Brugada syndrome reveals involvement of DIIIS4-S5 linker in slow inactivation

scientific article published on 22 August 2007

Chemokine ligand 9 modulates cardiac repolarization via Cxcr3 receptor binding

scientific article published on 31 July 2015

Chronic performance of a leadless cardiac pacemaker: 1-year follow-up of the LEADLESS trial

scientific article

Classification and Reporting of Potentially Proarrhythmic Common Genetic Variation in Long QT Syndrome Genetic Testing.

scientific article published in February 2018

Clinical Aspects of Type 3 Long-QT Syndrome: An International Multicenter Study

scientific article published on 26 August 2016

Clinical Assessment of the Pathogenicity of Unknown Variants in Long-QT Syndrome: Does the Pendulum Swing Back?

scientific article published on 04 April 2012

Clinical Management of Catecholaminergic Polymorphic Ventricular Tachycardia: The Role of Left Cardiac Sympathetic Denervation.

scientific article published on 27 May 2015

Clinical and genetic analysis of long QT syndrome in children from six families in Saudi Arabia: are they different?

scientific article published on 30 January 2009

Clinical and genetic characterization of patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy caused by a plakophilin-2 splice mutation

scientific article published on 7 November 2012

Clinical aspects and prognosis of Brugada syndrome in children

scientific article published on 2 April 2007

Clinical aspects of type-1 long-QT syndrome by location, coding type, and biophysical function of mutations involving the KCNQ1 gene

scientific article published on 30 April 2007

Clinical utility gene card for: Long-QT Syndrome (types 1–13) ⬇️

scientific article published on March 20, 2013

Clinical parameters to optimize patient selection for subcutaneous and transvenous implantable defibrillator therapy

scientific article published on 13 June 2018

Combined assessment of sex- and mutation-specific information for risk stratification in type 1 long QT syndrome

scientific article published on 28 January 2012

Combined leadless pacemaker and subcutaneous implantable defibrillator therapy: feasibility, safety, and performance

scientific article

Common sodium channel promoter haplotype in asian subjects underlies variability in cardiac conduction.

scientific article published on 16 January 2006

Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death

scientific article

Communicating Antitachycardia Pacing-Enabled Leadless Pacemaker and Subcutaneous Implantable Defibrillator

scientific article published on 21 March 2016

Comparison of complications and shocks in paediatric and young transvenous and subcutaneous implantable cardioverter-defibrillator patients

scientific article published on 01 December 2018

Complex inheritance for susceptibility to sudden cardiac death.

scientific article published on January 2013

Complications related to elective generator replacement of the subcutaneous implantable defibrillator

scientific article published on 16 November 2020

Compound heterozygosity for mutations (W156X and R225W) in SCN5A associated with severe cardiac conduction disturbances and degenerative changes in the conduction system

scientific article published on February 2003

Computer versus Cardiologist: Is a machine learning algorithm able to outperform an expert in diagnosing phospholamban (PLN) p.Arg14del mutation on ECG?

scientific article published on 07 September 2020

Con: Newborn screening to prevent sudden cardiac death?

scientific article published on 11 October 2006

Congenital Long QT Syndrome: An Update and Present Perspective in Saudi Arabia

scientific article

Continued misuse of orphan drug legislation: a life-threatening risk for mexiletine

scientific article published on 01 February 2020

Contribution of inherited heart disease to sudden cardiac death in childhood

scientific article published in October 2007

Contribution of sodium channel mutations to bradycardia and sinus node dysfunction in LQT3 families

scientific article published on 3 April 2003

Corrigendum to: 'HRS/EHRA Expert Consensus Statement on the State of Genetic Testing for the Channelopathies and Cardiomyopathies' [Europace 2011;13:1077-109, doi: 10.1093/europace/eur245]

scientific article published on 20 January 2012

Cost-effectiveness of genotyping in inherited arrhythmia syndromes: are we getting value for the money?

scientific article published on 01 February 2009

Coxsackie and adenovirus receptor is a modifier of cardiac conduction and arrhythmia vulnerability in the setting of myocardial ischemia

scientific article

Creating certainty out of uncertainty

scientific article published on 01 March 2019

Delay in right ventricular activation contributes to Brugada syndrome

scientific article published in March 2004

Desmin mutations as a cause of right ventricular heart failure affect the intercalated disks

scientific article published on 24 April 2010

Desmoglein-2 and desmocollin-2 mutations in dutch arrhythmogenic right ventricular dysplasia/cardiomypathy patients: results from a multicenter study

scientific article published on 01 August 2009

Desmosomal mutations across the fence ⬇️

scientific article published on 01 April 2011

Detailed characterization of familial idiopathic ventricular fibrillation linked to the DPP6 locus

scientific article

Determination and Interpretation of the QT Interval

scientific article published on 01 November 2018

Developmental aspects of long QT syndrome type 3 and Brugada syndrome on the basis of a single SCN5A mutation in childhood

scientific article published on 01 July 2005

Device orientation of a leadless pacemaker and subcutaneous implantable cardioverter-defibrillator in canine and human subjects and the effect on intrabody communication

scientific article published on 01 November 2018

Diagnostic Performance of Various QTc Interval Formulas in a Large Family with Long QT Syndrome Type 3: Bazett's Formula Not So Bad After All … ⬇️

scientific article published on 01 October 2003

Diagnostic and genetic aspects of the Brugada and other inherited arrhythmias syndromes.

scientific article

Diagnostic criteria for congenital long QT syndrome in the era of molecular genetics: do we need a scoring system?

article

Diagnostic criteria for congenital long QT syndrome in the era of molecular genetics: do we need a scoring system?

scientific article published on 05 May 2007

Diagnostic value of T-wave morphology changes during "QT stretching" in patients with long QT syndrome

scientific article published on 30 June 2015

Diagnostic value of flecainide testing in unmasking SCN5A-related Brugada syndrome

scientific article published on 09 June 2006

Diagnostic yield in sudden unexplained death and aborted cardiac arrest in the young: the experience of a tertiary referral center in The Netherlands

scientific article published on 31 May 2010

Dilation of the Aorta Ascendens Forms Part of the Clinical Spectrum of HCN4 Mutations

scientific article published on 01 May 2016

Direct comparison of a contractility and activity pacemaker sensor during treadmill exercise testing

scientific article published in November 2004

Disparate response of high-frequency ganglionic plexus stimulation on sinus node function and atrial propagation in patients with atrial fibrillation

scientific article published on 03 September 2014

Distinguishing arrhythmogenic right ventricular cardiomyopathy/dysplasia-associated mutations from background genetic noise.

scientific article published in June 2011

Diurnal variation of ventricular repolarization in a large family with LQT3-Brugada syndrome characterized by nocturnal sudden death

scientific article

Diversity in cardiac sodium channel disease phenotype in transgenic mice carrying a single SCN5A mutation.

scientific article published on January 2007

Do J waves constitute a syndrome? ⬇️

scientific article published on July 15, 2013

Do patients with long QT syndrome remain at risk for sudden cardiac death after 40 years of age?

scientific article published on 29 July 2008

Documented atrial fibrillation recurrences after pulmonary vein isolation are associated with diminished quality of life

scientific article published on 7 May 2015

Does flecainide regain its antiarrhythmic activity after electrical cardioversion of persistent atrial fibrillation?

scientific article published in March 2005

Double trouble, stick to the basics should be the rule!

scientific article published on 22 July 2014

Drugs and Brugada syndrome patients: review of the literature, recommendations, and an up-to-date website (www.brugadadrugs.org)

scientific article

Dual inheritance of sudden death from cardiovascular causes

scientific article published in May 2008

Dutch outcome in implantable cardioverter-defibrillator therapy (DO-IT): registry design and baseline characteristics of a prospective observational cohort study to predict appropriate indication for implantable cardioverter-defibrillator

scientific article published on 07 August 2017

ECG quantification of myocardial scar does not differ between primary and secondary prevention ICD recipients with ischemic heart disease

scientific article published on 04 November 2009

ECG screening of newborns to avoid sudden infant death syndrome?

scientific article published on February 2006

EP testing does not predict cardiac events in Brugada syndrome ⬇️

scientific article published on July 20, 2011

ESC guidance for the diagnosis and management of cardiovascular disease during the COVID-19 pandemic: part 2—care pathways, treatment, and follow-up

scientific article

Early Mechanical Alterations in Phospholamban Mutation Carriers: Identifying Subclinical Disease Before Onset of Symptoms

scientific article published on 13 November 2020

Early mortality in prophylactic implantable cardioverter-defibrillator recipients: development and validation of a clinical risk score

scientific article

Effect of Age and Sex on the QTc Interval in Children and Adolescents With Type 1 and 2 Long-QT Syndrome

scientific article published on April 2017

Effect of Ascertainment Bias on Estimates of Patient Mortality in Inherited Cardiac Diseases

article

Effect of age and gender on the QTc-interval in healthy individuals and patients with long-QT syndrome

scientific article published on 3 August 2017

Effects of flecainide on exercise-induced ventricular arrhythmias and recurrences in genotype-negative patients with catecholaminergic polymorphic ventricular tachycardia.

scientific article published on 31 December 2012

Efficacy of an implantable cardioverter-defibrillator in a neonate with LQT3 associated arrhythmias

scientific article published in January 2005

Electrocardiographic P wave changes after thoracoscopic pulmonary vein isolation for atrial fibrillation.

scientific article published on 16 April 2013

Electrocardiographic factors playing a role in ischemic ventricular fibrillation in ST elevation myocardial infarction are related to the culprit artery

scientific article published on 19 September 2007

Empiric quinidine therapy for asymptomatic Brugada syndrome: time for a prospective registry

scientific article

Enhancing the Predictive Power of Mutations in the C-Terminus of the KCNQ1-Encoded Kv7.1 Voltage-Gated Potassium Channel

scientific article published on 09 April 2015

Epicardial Substrate Ablation in Brugada Syndrome: Time for a Randomized Trial!

scientific article published on 01 December 2015

Epicardial and endocardial electrophysiological guided thoracoscopic surgery for atrial fibrillation: a multidisciplinary approach of atrial fibrillation ablation in challenging patients

scientific article published on 28 February 2014

Epidemiologic, molecular, and functional evidence suggest A572D-SCN5A should not be considered an independent LQT3-susceptibility mutation.

scientific article

Epidemiology of inherited arrhythmias

scientific article published on 03 October 2019

Ethnic differences in patients with Brugada syndrome and arrhythmic events: New insights from Survey on Arrhythmic Events in Brugada Syndrome

scientific article published on 05 July 2019

European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) expert consensus on risk assessment in cardiac arrhythmias: use the right tool for the right out

scientific article published in August 2020

European recommendations integrating genetic testing into multidisciplinary management of sudden cardiac death

article published in 2019

Evaluation of the Impact of a Chronic Total Coronary Occlusion on Ventricular Arrhythmias and Long-Term Mortality in Patients With Ischemic Cardiomyopathy and an Implantable Cardioverter-Defibrillator (the eCTOpy-in-ICD Study).

scientific article published on 2 May 2018

Everybody has Brugada syndrome until proven otherwise?

scientific article published on 18 May 2015

Exclusion of multiple candidate genes and large genomic rearrangements in SCN5A in a Dutch Brugada syndrome cohort

scientific article published on 02 March 2007

Exercise extreme caution when calling rare genetic variants novel arrhythmia syndrome susceptibility mutations ⬇️

scientific article published on October 13, 2010

Exercise related syncope, when it's not the heart

scientific article published in October 2004

Exercise-induced ECG changes in Brugada syndrome.

scientific article

Expanding spectrum of human RYR2-related disease: new electrocardiographic, structural, and genetic features

scientific article

Facilitatory and inhibitory effects of SCN5A mutations on atrial fibrillation in Brugada syndrome ⬇️

scientific article published on January 26, 2011

Familial disease with a risk of sudden death: a longitudinal study of the psychological consequences of predictive testing for long QT syndrome

scientific article published on 30 January 2008

Familial evaluation in catecholaminergic polymorphic ventricular tachycardia: disease penetrance and expression in cardiac ryanodine receptor mutation-carrying relatives

scientific article published on 10 July 2012

Familial primary arrhythmia syndromes: Nice to know or need to know

scientific article published on May 2002

Familial sudden death is an important risk factor for primary ventricular fibrillation: a case-control study in acute myocardial infarction patients

scientific article published on 28 August 2006

Fever increases the risk for cardiac arrest in the Brugada syndrome

scientific article published on 01 August 2008

Fever-Related Arrhythmic Events in the Multicenter Survey on Arrhythmic Events in Brugada Syndrome (SABRUS).

scientific article published on 9 April 2018

Fever-induced QTc prolongation and ventricular arrhythmias in individuals with type 2 congenital long QT syndrome

scientific article

Fever-triggered ventricular arrhythmias in Brugada syndrome and type 2 long-QT syndrome.

scientific article

Fibrosis, Connexin-43, and Conduction Abnormalities in the Brugada Syndrome.

scientific article

First experience with the wearable cardioverter defibrillator in the Netherlands

scientific article published on February 2012

Flecainide prevents catecholaminergic polymorphic ventricular tachycardia in mice and humans

scientific article

Flecainide therapy reduces exercise-induced ventricular arrhythmias in patients with catecholaminergic polymorphic ventricular tachycardia

scientific article

Founder mutations in hypertrophic cardiomyopathy patients in the Netherlands

scientific article

Founder mutations in the Netherlands: SCN5a 1795insD, the first described arrhythmia overlap syndrome and one of the largest and best characterised families worldwide

scientific article

Founder mutations in the Netherlands: familial idiopathic ventricular fibrillation and DPP6 ⬇️

scientific article published on June 1, 2011

From whole exome sequencing to patient-specific therapy: another example of how basic research pays off in patient care

scientific article published on 26 May 2015

Functional assessment of potential splice site variants in arrhythmogenic right ventricular dysplasia/cardiomyopathy

scientific article (publication date: November 2014)

GENCOR: a national registry for patients and families suffering from a familial heart disease in the Netherlands

scientific article published on August 2006

GNB5 Mutations Cause an Autosomal-Recessive Multisystem Syndrome with Sinus Bradycardia and Cognitive Disability

scientific article published on September 2016

GNB5 Mutations Cause an Autosomal-Recessive Multisystem Syndrome with Sinus Bradycardia and Cognitive Disability.

scientific article published on 10 August 2016

Gain-of-function mutation in SCN5A causes ventricular arrhythmias and early onset atrial fibrillation

scientific article published on 29 January 2017

Gender differences in patients with Brugada syndrome and arrhythmic events: Data from a survey on arrhythmic events in 678 patients

scientific article published on 13 June 2018

Gender differences in the long QT syndrome: effects of beta-adrenoceptor blockade

scientific article published on 01 February 2002

Gender-specific differences in major cardiac events and mortality in lamin A/C mutation carriers.

scientific article

Gene-specific increase in the energetic cost of contraction in hypertrophic cardiomyopathy caused by thick filament mutations

article

Genetic Basis of Ventricular Arrhythmias.

scientific article published on 03 September 2010

Genetic Causes in Cardiac Arrest Survivors: Fake News or the Real Deal?

scientific article published on 01 June 2017

Genetic Control of Potassium Channels

scientific article published on 26 March 2016

Genetic Susceptibility for COVID-19-Associated Sudden Cardiac Death in African Americans

scientific article published on 04 May 2020

Genetic analysis in 418 index patients with idiopathic dilated cardiomyopathy: overview of 10 years' experience

article

Genetic and clinical advances in congenital long QT syndrome

scientific article published in October 2014

Genetic arrhythmias complicating patients with dilated cardiomyopathy

scientific article published on 12 September 2019

Genetic aspects of vasovagal syncope: a systematic review of current evidence

scientific article published on 18 January 2009

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization

scientific article

Genetic basis of malignant channelopathies and ventricular fibrillation in the structurally normal heart

scientific article published on May 2010

Genetic control of sodium channel function

scientific article

Genetic counseling and cardiac care in predictively tested hypertrophic cardiomyopathy mutation carriers: the patients' perspective

scientific article published in July 2009

Genetic knowledge and counselling skills of Dutch cardiologists: sufficient for the genomics era?

scientific article published on 01 March 2003

Genetic predisposition for sudden cardiac death in myocardial ischaemia: the Arrhythmia Genetics in the NEtherlandS study ⬇️

scientific article published on January 28, 2011

Genetic screening in acquired long QT syndrome? CAUTION: proceed carefully

scientific article published on 30 December 2015

Genetic testing for inherited cardiac disease ⬇️

scientific article published on July 30, 2013

Genetic testing for long-QT syndrome: distinguishing pathogenic mutations from benign variants.

scientific article

Genetic testing in cardiovascular diseases

scientific article published on May 2010

Genetic variation in SCN10A influences cardiac conduction

scientific article

Genetically determined differences in sodium current characteristics modulate conduction disease severity in mice with cardiac sodium channelopathy

scientific article published on 30 April 2009

Genetics of cardiac arrhythmias

scientific article

Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes

scientific article (publication date: 2013)

Genome-wide association study identifies a susceptibility locus at 21q21 for ventricular fibrillation in acute myocardial infarction

scientific article

Genotype and clinical characteristics of congenital long QT syndrome in Thailand

scientific article published on 20 July 2018

Genotype-phenotype aspects of type 2 long QT syndrome

scientific article

Genotype-phenotype dilemma in a case of sudden cardiac death with the E1053K mutation and a deletion in the SCN5A gene

scientific article published on 20 March 2017

Genotype-phenotype relationship in Brugada syndrome: electrocardiographic features differentiate SCN5A-related patients from non-SCN5A-related patients

scientific article published on 01 July 2002

Genotype-specific onset of arrhythmias in congenital long-QT syndrome: possible therapy implications

scientific article published on 06 November 2006

HERG mutation predicts short QT based on channel kinetics but causes long QT by heterotetrameric trafficking deficiency.

scientific article published on August 2005

HRS/EHRA expert consensus statement on the state of genetic testing for the channelopathies and cardiomyopathies this document was developed as a partnership between the Heart Rhythm Society (HRS) and the European Heart Rhythm Association (EHRA).

scientific article published on August 2011

HRS/EHRA expert consensus statement on the state of genetic testing for the channelopathies and cardiomyopathies: this document was developed as a partnership between the Heart Rhythm Society (HRS) and the European Heart Rhythm Association (EHRA).

scientific article published on August 2011

Haplotype-sharing analysis implicates chromosome 7q36 harboring DPP6 in familial idiopathic ventricular fibrillation

scientific article published on 12 March 2009

Health-related quality of life impact of a transcatheter pacing system

scientific article published on 15 October 2018

Heart Rate Recovery After Exercise Is Associated With Arrhythmic Events in Patients With Catecholaminergic Polymorphic Ventricular Tachycardia

scientific article published on 16 February 2020

Heart failure following STEMI: a contemporary cohort study of incidence and prognostic factors

scientific article published on 22 December 2017

Heritability in genetic heart disease: the role of genetic background

scientific article published on 28 May 2019

High diagnostic yield and accuracy of history, physical examination, and ECG in patients with transient loss of consciousness in FAST: the Fainting Assessment study

scientific article

High distress in parents whose children undergo predictive testing for long QT syndrome

scientific article published on 01 January 2005

High yield of LMNA mutations in patients with dilated cardiomyopathy and/or conduction disease referred to cardiogenetics outpatient clinics

article

How do hypertrophic cardiomyopathy mutations affect myocardial function in carriers with normal wall thickness? Assessment with cardiovascular magnetic resonance.

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I Ks in Heart and Hearing, the Ear Can Do with Less than the Heart ⬇️

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I don't know what it is, but it doesn't feel right

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I think a niece of mine was referred to a neurologist

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IK1 modulates the U-wave: insights in a 100-year-old enigma

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Identification of a possible pathogenic link between congenital long QT syndrome and epilepsy

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Identification of a sudden cardiac death susceptibility locus at 2q24.2 through genome-wide association in European ancestry individuals

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Identification of sarcomeric variants in probands with a clinical diagnosis of arrhythmogenic right ventricular cardiomyopathy (ARVC)

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Images in cardiovascular medicine. Prominent crypt formation in the inferoseptum of a hypertrophic cardiomyopathy mutation carrier mimics noncompaction cardiomyopathy

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Impact of Leadless Pacemaker Therapy on Cardiac and Atrioventricular Valve Function Through 12 Months of Follow-Up

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Impact of cardiac complications on outcome after aneurysmal subarachnoid hemorrhage: a meta-analysis

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Impact of genetics on the clinical management of channelopathies

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Implantable cardioverter defibrillator as a bridge to recovery in an infant with cardiac rhabdomyoma

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Implantable cardioverter defibrillator therapy in adults with congenital heart disease: who is at risk of shocks?

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Implantable cardioverter-defibrillator harm in young patients with inherited arrhythmia syndromes: A systematic review and meta-analysis of inappropriate shocks and complications

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Importance of Validating Guideline Recommendations

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Improving long QT syndrome diagnosis by a polynomial-based T-wave morphology characterization

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Improving the care for female subcutaneous ICD patients: A qualitative study of gender-specific issues

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Improving usual care after sudden death in the young with focus on inherited cardiac diseases (the CAREFUL study): a community-based intervention study

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In Children and Adolescents From Brugada Syndrome-Families, Only SCN5A Mutation Carriers Develop a Type-1 ECG Pattern Induced By Fever

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In search of the holy grail in the channelopathy field: Proving pathogenicity of long QT syndrome-associated variants?

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In silico cardiac risk assessment in patients with long QT syndrome: type 1: clinical predictability of cardiac models

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In-hospital cardiac arrest is associated with use of non-antiarrhythmic QTc-prolonging drugs

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Inaccessibility to quinidine therapy is about to get worse

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Inappropriate shocks in the subcutaneous ICD: Incidence, predictors and management.

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Inappropriate subcutaneous implantable cardioverter-defibrillator shocks due to T-wave oversensing can be prevented: implications for management

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Incidence, causes, and outcomes of out-of-hospital cardiac arrest in children. A comprehensive, prospective, population-based study in the Netherlands

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Induced pluripotent stem cell derived cardiomyocytes as models for cardiac arrhythmias

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Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

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Is there a genetic basis for malignant ventricular arrhythmias?

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It's not what you think it is.

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J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge

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J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge

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J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge.

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Just one collapse during soccer

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Lack of genotype-phenotype correlation in Brugada Syndrome and Sudden Arrhythmic Death Syndrome families with reported pathogenic SCN1B variants

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Lamin A/C mutation is independently associated with an increased risk of arterial and venous thromboembolic complications

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Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci

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Late Sodium Current Inhibition in Acquired and Inherited Ventricular (dys)function and Arrhythmias ⬇️

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Leadless pacemaker implantation after explantation of infected conventional pacemaker systems: A viable solution?

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Left Axis Deviation in Brugada Syndrome: Vectorcardiographic Evaluation during Ajmaline Provocation Testing Reveals Additional Depolarization Abnormalities

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Left cardiac sympathetic denervation for catecholaminergic polymorphic ventricular tachycardia

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Left cardiac sympathetic denervation in the Netherlands for the treatment of inherited arrhythmia syndromes

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Letter by Amin et al Regarding Article, "Genetic Modifiers for the Long-QT Syndrome: How Important Is the Role of Variants in the 3' Untranslated Region of KCNQ1?"

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Life-threatening arrhythmias with autosomal recessive TECRL variants

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Linking the heart and the brain: Neurodevelopmental disorders in patients with catecholaminergic polymorphic ventricular tachycardia

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Local depolarization abnormalities are the dominant pathophysiologic mechanism for type 1 electrocardiogram in brugada syndrome a study of electrocardiograms, vectorcardiograms, and body surface potential maps during ajmaline provocation

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Long QT syndrome caused by a large duplication in the KCNH2 (HERG) gene undetectable by current polymerase chain reaction-based exon-scanning methodologies.

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Long QT syndrome: a double hit hurts more

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Long QT syndrome: beyond the causal mutation ⬇️

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Long-term prognosis of individuals with right precordial ST-segment-elevation Brugada syndrome

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Long-term prognosis of patients diagnosed with Brugada syndrome: Results from the FINGER Brugada Syndrome Registry

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Loss-of-Function KCNE2 Variants: True Monogenic Culprits of Long-QT Syndrome or Proarrhythmic Variants Requiring Secondary Provocation?

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Loss-of-function sodium channel mutations in infancy: a pattern unfolds

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Low rate of cardiac events in first-degree relatives of diagnosis-negative young sudden unexplained death syndrome victims during follow-up

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Manifest disease, risk factors for sudden cardiac death, and cardiac events in a large nationwide cohort of predictively tested hypertrophic cardiomyopathy mutation carriers: determining the best cardiological screening strategy

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Mechanism of right precordial ST-segment elevation in structural heart disease: excitation failure by current-to-load mismatch.

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Mechanisms of inherited cardiac conduction disease

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Microvolt T-wave alternans during exercise and pacing are not comparable

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Midterm Safety and Performance of a Leadless Cardiac Pacemaker: 3-Year Follow-up to the LEADLESS Trial (Nanostim Safety and Performance Trial for a Leadless Cardiac Pacemaker System).

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Mild-to-moderate kidney dysfunction and the risk of sudden cardiac death in the setting of acute myocardial infarction ⬇️

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Minimal defibrillation thresholds and the correlation with implant position in subcutaneous implantable-defibrillator patients

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Mortality Risk Associated With Truncating Founder Mutations in Titin

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Mortality of Inherited Arrhythmia Syndromes

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Mortality risk of untreated myosin-binding protein C-related hypertrophic cardiomyopathy: insight into the natural history

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Mothers with long QT syndrome are at increased risk for fetal death: findings from a multicenter international study

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Multifocal ectopic Purkinje-related premature contractions: a new SCN5A-related cardiac channelopathy

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Multilevel analyses of SCN5A mutations in arrhythmogenic right ventricular dysplasia/cardiomyopathy suggest non-canonical mechanisms for disease pathogenesis

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Mutation Location Effect on Severity of Phenotype During Exercise Testing in Type 1 Long‐QT Syndrome: Impact of Transmembrane and C‐Loop Location ⬇️

scientific article published on May 20, 2013

Mutation and gender-specific risk in type 2 long QT syndrome: implications for risk stratification for life-threatening cardiac events in patients with long QT syndrome

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Mutation in the KCNQ1 gene leading to the short QT-interval syndrome

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Mutations in conserved amino acids in the KCNQ1 channel and risk of cardiac events in type-1 long-QT syndrome

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Myocardial fibrosis as an early feature in phospholamban p.Arg14del mutation carriers: phenotypic insights from cardiovascular magnetic resonance imaging

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Myocarditis in patients with subarachnoid hemorrhage: A histopathologic study

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Myocyte necrosis underlies progressive myocardial dystrophy in mouse dsg2-related arrhythmogenic right ventricular cardiomyopathy

scientific article published on 27 July 2009

Na+ channel mutation leading to loss of function and non-progressive cardiac conduction defects

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Narrow QRS complexes intervening wide QRS complexes

Narrow QRS complexes intervening wide QRS complexes.

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Navigating the mini-maze: systematic review of the first results and progress of minimally-invasive surgery in the treatment of atrial fibrillation

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New ECG criteria in arrhythmogenic right ventricular dysplasia/cardiomyopathy

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Next-generation sequencing using microfluidic PCR enrichment for molecular autopsy

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Nightly phenomena, day time work?

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Nodoventricular accessory pathways in PRKAG2-dependent familial preexcitation syndrome reveal a disorder in cardiac development.

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Non-compaction: a distinct cardiomyopathy or non-specific morphological trait?

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Not all beta-blockers are equal in the management of long QT syndrome types 1 and 2: higher recurrence of events under metoprolol

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Not just any ICD device in patients with long-QT syndrome

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Novel electrocardiographic criteria for the diagnosis of arrhythmogenic right ventricular cardiomyopathy

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Now you see it, now you don't

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Obtaining insurance after DNA diagnostics: a survey among hypertrophic cardiomyopathy mutation carriers

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One to one, one to two, two to one? What is the rhythm?

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Out of the frying pan and into the fire

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Outcome in phospholamban R14del carriers: results of a large multicentre cohort study

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Outpatient treatment with the wearable cardioverter defibrillator: clinical experience in two Dutch centres

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Overlap syndrome of cardiac sodium channel disease in mice carrying the equivalent mutation of human SCN5A-1795insD

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P336Exome sequencing of multiple affected individuals from an Irish family with Brugada Syndrome uncovers a novel locus for the disorder

Palpitations again, have a close look

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Palpitations and dizziness in a 65-year-old man.

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Palpitations in a 19-year old man and a slow heart rate at rest

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Palpitations in a 19-year old man and a slow heart rate at rest

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Palpitations in a 19-year-old man, take a second look

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Palpitations in a 19-year-old man, take a second look

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Palpitations, once again

Palpitations, once again

Palpitations, should one worry?

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Palpitations, should one worry?

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Pathophysiological mechanisms of Brugada syndrome: depolarization disorder, repolarization disorder, or more?

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Penetrance of Hypertrophic Cardiomyopathy in Children Who Are Mutation Positive

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Permanent leadless cardiac pacing: results of the LEADLESS trial.

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Phenotypical Manifestations of Mutations in the Genes Encoding Subunits of the Cardiac Sodium Channel ⬇️

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Phospholamban R14del mutation in patients diagnosed with dilated cardiomyopathy or arrhythmogenic right ventricular cardiomyopathy: evidence supporting the concept of arrhythmogenic cardiomyopathy

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Phylogenetic and physicochemical analyses enhance the classification of rare nonsynonymous single nucleotide variants in type 1 and 2 long-QT syndrome

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Plakophilin-2 mutations are the major determinant of familial arrhythmogenic right ventricular dysplasia/cardiomyopathy

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Postmortem Histopathological Examination of a Leadless Pacemaker Shows Partial Encapsulation After 19 Months

scientific article published in October 2015

Postpacing abnormal repolarization in catecholaminergic polymorphic ventricular tachycardia associated with a mutation in the cardiac ryanodine receptor gene.

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Prediction of ventricular arrhythmia in phospholamban p.Arg14del mutation carriers-reaching the frontiers of individual risk prediction

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Pregnancy and the risk of torsades de pointes in congenital long-QT syndrome

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Prevalence and characterization of ECG abnormalities after intracerebral hemorrhage

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Primary prevention: prime time?: ICD trials (and tribulations).

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Primary ventricular fibrillation in acute myocardial infarction: an inherited disease?

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Profile of Brugada Syndrome Patients Presenting with Their First Documented Arrhythmic Event. Data from the Survey on Arrhythmic Events in BRUgada Syndrome (SABRUS).

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Prognosis among survivors of primary ventricular fibrillation in the percutaneous coronary intervention era

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Prognostic implications of mutation-specific QTc standard deviation in congenital long QT syndrome ⬇️

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Prognostic significance of fever-induced Brugada syndrome.

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Programmed Ventricular Stimulation for Risk Stratification in the Brugada Syndrome: A Pooled Analysis

scientific article published on 21 January 2016

Prophylactic (hydroxy)chloroquine in COVID-19: potential relevance for cardiac arrhythmia risk

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Proposed Diagnostic Criteria for the Brugada Syndrome

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Proposed diagnostic criteria for the Brugada syndrome

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Proposed diagnostic criteria for the Brugada syndrome: consensus report

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QT Prolongation and Mortality in Hospital Settings: Identifying Patients at High Risk ⬇️

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Quality of life and psychological distress in hypertrophic cardiomyopathy mutation carriers: a cross-sectional cohort study

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Quantitative trait loci for electrocardiographic parameters and arrhythmia in the mouse

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Quinidine, a life-saving medication for Brugada syndrome, is inaccessible in many countries

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Rationale and design of the CAREFUL study : The yield of CARdiogenetic scrEening in First degree relatives of sudden cardiac and UnexpLained death victims <45 years

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Rationale and design of the PRAETORIAN trial: a Prospective, RAndomizEd comparison of subcuTaneOus and tRansvenous ImplANtable cardioverter-defibrillator therapy

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Rationale and design of the PRAETORIAN-DFT trial: A prospective randomized CompArative trial of SubcutanEous ImplanTable CardiOverter-DefibrillatoR ImplANtation with and without DeFibrillation testing

scientific article published on 16 May 2019

Rationale of the SEAS study: Serial Echocardiography After Subarachnoid haemorrhage, a prospective national, multicentre, multidisciplinary, cohort study to evaluate cardiac abnormalities following intracranial haemorrhage

scientific article published on November 2006

Readthrough-Promoting Drugs Gentamicin and PTC124 Fail to Rescue Nav1.5 Function of Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Carrying Nonsense Mutations in the Sodium Channel Gene SCN5A.

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Reappraisal of Reported Genes for Sudden Arrhythmic Death: An Evidence-Based Evaluation of Gene Validity for Brugada Syndrome

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Rebuttal to EP testing predicts cardiac events in patients with Brugada syndrome ⬇️

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Recent breakthroughs in the genetics of atrial fibrillation

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Recurrent and Founder Mutations in the Netherlands: the Long-QT Syndrome

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Recurrent and founder mutations in the Netherlands : Plakophilin-2 p.Arg79X mutation causing arrhythmogenic right ventricular cardiomyopathy/dysplasia

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Recurrent and founder mutations in the Netherlands—Phospholamban p.Arg14del mutation causes arrhythmogenic cardiomyopathy ⬇️

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Recurrent intrauterine fetal loss due to near absence of HERG: clinical and functional characterization of a homozygous nonsense HERG Q1070X mutation

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Relation Between Basic and Clinical Electrophysiologic Characteristics in Brugada Syndrome: Facts or Fiction? ⬇️

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Relationship Between Cardiac Dysfunction and Cerebral Perfusion in Patients with Aneurysmal Subarachnoid Hemorrhage

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Reply: Search for Evidence-Based Medicine for Brugada Syndrome: The Complex Network of the Brugada Syndrome

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Repolarization Versus Depolarization Defects in Brugada Syndrome: A Tale of 2 Different Electrophysiologic Settings?

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Response by Wilde and Gollob to Letter Regarding Article, "Reappraisal of Reported Genes for Sudden Arrhythmic Death: Evidence-Based Evaluation of Gene Validity for Brugada Syndrome"

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Response to Letters Regarding Article, "Clinical Management of Catecholaminergic Polymorphic Ventricular Tachycardia: The Role of Left Cardiac Sympathetic Denervation".

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Response to letter from Drs. Li et al. regarding our paper in Int. J. Cardiol. 2018. Doi: 10.1016/j.ijcard.2017.09.010: SCN5A mutation type and topology are associated with the risk of ventricular arrhythmia by sodium channel blockers

scientific article published on 01 November 2018

Revisiting the sensitivity of sodium channel blocker testing in Brugada syndrome using obligate transmittance

scientific article published on 05 July 2017

Right ventricular fibrosis and conduction delay in a patient with clinical signs of Brugada syndrome: a combined electrophysiological, genetic, histopathologic, and computational study.

scientific article published on November 2005

Right you are.

scientific article published on December 2005

Risk Factors for Malignant Ventricular Arrhythmias in Lamin A/C Mutation Carriers

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Risk Stratification in Brugada Syndrome: The "Impossible" Made Possible?

scientific article published on 01 March 2016

Risk for life-threatening cardiac events in patients with genotype-confirmed long-QT syndrome and normal-range corrected QT intervals

scientific article published in January 2011

Risk stratification for sudden cardiac death in hypertrophic cardiomyopathy: Dutch cardiologists and the care of mutation carriers

scientific article published on December 2009

Risk stratification for sudden cardiac death in hypertrophic cardiomyopathy: systematic review of clinical risk markers

scientific article published on 29 January 2010

Risk stratification in Brugada syndrome: Where is the finish line?

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Role of Genetic Testing in Patients with Ventricular Arrhythmias in Apparently Normal Hearts

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Role of common and rare variants in SCN10A: results from the Brugada syndrome QRS locus gene discovery collaborative study.

scientific article published on 17 February 2015

Role of programmed ventricular stimulation in patients with Brugada syndrome: a meta-analysis of worldwide published data

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Role of sequence variations in the human ether-a-go-go-related gene (HERG, KCNH2) in the Brugada syndrome

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Role of the Purkinje system in heritable arrhythmias

scientific article published on 02 February 2019

SARS-CoV-2, COVID-19 and inherited arrhythmia syndromes

scientific article published on 31 March 2020

SCN5A Mutation Type and a Genetic Risk Score Associate Variably with Brugada Syndrome Phenotype in SCN5A Families

scientific article published on 09 November 2020

SCN5A mutation type and topology are associated with the risk of ventricular arrhythmia by sodium channel blockers

scientific article published on 30 April 2018

SCN5A mutations and the role of genetic background in the pathophysiology of Brugada syndrome

scientific article published on 29 September 2009

SCN5A mutations in 442 neonates and children: genotype-phenotype correlation and identification of higher-risk subgroups

scientific article published in August 2018

SCN5A mutations in Brugada syndrome are associated with increased cardiac dimensions and reduced contractility

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SCN5A overlap syndromes: no end to disease complexity?

scientific article published on 26 September 2008

SCN5A variants in Brugada syndrome: True, true false or false true

scientific article published on 12 November 2018

SNPs identified as modulators of ECG traits in the general population do not markedly affect ECG traits during acute myocardial infarction nor ventricular fibrillation risk in this condition.

scientific article published on 20 February 2013

ST-Segment Elevation and Fractionated Electrograms in Brugada Syndrome Patients Arise From the Same Structurally Abnormal Subepicardial RVOT Area but Have a Different Mechanism

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Safe drug use in long QT syndrome and Brugada syndrome: comparison of website statistics

scientific article published on 26 March 2013

Scar tissue and microvolt T-wave alternans

scientific article published on 23 February 2014

Should I be worried?

scientific article published on January 2006

Slow and Discontinuous Conduction Conspire in Brugada Syndrome: A Right Ventricular Mapping and Stimulation Study

scientific article published on 02 December 2008

Sodium Channelopathies: Do We Really Understand What's Going On? ⬇️

scientific article published on August 31, 2010

Sodium channel β1 subunit mutations associated with Brugada syndrome and cardiac conduction disease in humans

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Somatic mosaicism contributes to phenotypic variation in Timothy syndrome

scientific article published on 09 September 2011

Spectrum and prevalence of mutations from the first 2,500 consecutive unrelated patients referred for the FAMILION long QT syndrome genetic test

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Spontaneous electrocardiographic fluctuations in Brugada syndrome: does it matter?

scientific article published on 25 September 2006

Structural abnormalities of the inferoseptal left ventricular wall detected by cardiac magnetic resonance imaging in carriers of hypertrophic cardiomyopathy mutations

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Structurally Abnormal Myocardium Underlies Ventricular Fibrillation Storms in a Patient Diagnosed With the Early Repolarization Pattern

scientific article published on 16 September 2020

Subcutaneous or Transvenous Defibrillator Therapy

scientific article published on 01 August 2020

Subsequent Event Risk in Individuals With Established Coronary Heart Disease

scientific article published on 21 March 2019

Substitution of a conserved alanine in the domain IIIS4-S5 linker of the cardiac sodium channel causes long QT syndrome

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Sudden Cardiac Arrest and Rare Genetic Variants in the Community.

scientific article published on 22 January 2016

Sudden Cardiac Death Prediction in Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC): A Multinational Collaboration

scientific article published on 09 December 2020

Sudden cardiac death in the young: the molecular autopsy and a practical approach to surviving relatives.

scientific article published on 11 March 2015

Sudden death in the young: what do we know about it and how to prevent?

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Sudden unexplained death: heritability and diagnostic yield of cardiological and genetic examination in surviving relatives

scientific article published on 5 July 2005

Support vector machine-based assessment of the T-wave morphology improves long QT syndrome diagnosis

scientific article published on 01 November 2018

Supraventricular tachycardias, conduction disease, and cardiomyopathy in 3 families with the same rare variant in TNNI3K (p.Glu768Lys)

scientific article published on 17 August 2018

Surgical Management of Implantation-Related Complications of the Subcutaneous Implantable Cardioverter-Defibrillator

scientific article published on 17 October 2015

Switch From Fetal to Adult SCN5A Isoform in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Unmasks the Cellular Phenotype of a Conduction Disease-Causing Mutation

scientific article published on 24 July 2017

Symptoms and signs of syncope: a review of the link between physiology and clinical clues

scientific article published on 8 July 2009

Syncope and Exercise‐Related Ventricular Tachycardia ⬇️

scientific article published on April 1, 2012

Syncope during exercise, documented with continuous blood pressure monitoring during ergometer testing

scientific article published in February 2005

Syncope in Brugada syndrome: prevalence, clinical significance, and clues from history taking to distinguish arrhythmic from nonarrhythmic causes

scientific article published on 13 October 2014

Syncope in genotype-negative long QT syndrome family members

scientific article published on 30 July 2014

T-cell-mediated inflammatory activity in the stellate ganglia of patients with ion-channel disease and severe ventricular arrhythmias.

scientific article published on 14 February 2014

T-wave alternans in a patient with long-QT syndrome type 3.

scientific article published on April 2006

TDI-echocardiography: a new screening tool for long QT syndrome?

scientific article published on 01 September 2003

TGFβ‐inducible early gene‐1 (TIEG1) mutations in hypertrophic cardiomyopathy ⬇️

scientific article published on June 1, 2012

Targeting sodium channels in cardiac arrhythmia

scientific article published on 21 December 2013

Ten years of genes in inherited arrhythmia syndromes: an example of what we have learned from patients, electrocardiograms, and computers

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The "accordion sign," a new tune in arrhythmogenic right ventricular dysplasia/cardiomyopathy magnetic resonance imaging?

scientific article published on 01 April 2009

The 'president's drug'

scientific article published on 10 July 2020

The 2373insG mutation in the MYBPC3 gene is a founder mutation, which accounts for nearly one-fourth of the HCM cases in the Netherlands

scientific article published on 01 October 2003

The AV-node revisited.

scientific article published on November 2003

The Brugada ECG pattern: a marker of channelopathy, structural heart disease, or neither? Toward a unifying mechanism of the Brugada syndrome.

scientific article published on June 2010

The Brugada Syndrome Susceptibility Gene HEY2 Modulates Cardiac Transmural Ion Channel Patterning and Electrical Heterogeneity.

scientific article published on 21 June 2017

The ECG of a (cardio)myopathy?

scientific article published on October 2005

The ICD for primary prevention in patients with inherited cardiac diseases: indications, use, and outcome: a comparison with secondary prevention

scientific article published on 29 December 2012

The Netherlands Arrhythmogenic Cardiomyopathy Registry: design and status update

scientific article published on 01 October 2019

The Never Ending Story of Risk Stratification for Sudden Death in Hypertrophic Cardiomyopathy ⬇️

scientific article published on June 15, 2011

The RYR2-encoded ryanodine receptor/calcium release channel in patients diagnosed previously with either catecholaminergic polymorphic ventricular tachycardia or genotype negative, exercise-induced long QT syndrome: a comprehensive open reading [...]

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The Shanghai Score System in Brugada Syndrome: Using it Beyond a Diagnostic Score

scientific article published on 01 June 2018

The brisk-standing-test for long QT syndrome in prepubertal school children: defining normal.

scientific article published on 3 October 2017

The cardiac sodium channel displays differential distribution in the conduction system and transmural heterogeneity in the murine ventricular myocardium

scientific article (publication date: September 2009)

The cardiac sodium channel gene SCN5A and its gene product NaV1.5: Role in physiology and pathophysiology.

scientific article published on 08 September 2015

The chemical compound PTC124 does not affect cellular electrophysiology of cardiac ventricular myocytes.

scientific article published on February 2012

The common long-QT syndrome mutation KCNQ1/A341V causes unusually severe clinical manifestations in patients with different ethnic backgrounds: toward a mutation-specific risk stratification.

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The complexity of genotype-phenotype relations associated with loss-of-function sodium channel mutations and the role of in silico studies

scientific article published on 23 May 2008

The development and validation of an easy to use automatic QT-interval algorithm.

scientific article published on September 2017

The diagnostic and therapeutic aspects of loss-of-function cardiac sodium channelopathies in children ⬇️

scientific article published on August 8, 2012

The effect of revascularization of a chronic total coronary occlusion on electrocardiographic variables. A sub-study of the EXPLORE trial

scientific article published on 19 July 2018

The entirely subcutaneous implantable cardioverter-defibrillator: initial clinical experience in a large Dutch cohort

scientific article published on 10 October 2012

The genetic architecture of long QT syndrome: A critical reappraisal

scientific article published on 30 March 2018

The ions have it.

scientific article published on November 2005

The measurement of the QT interval

scientific article published on August 2014

The molecular genetics of arrhythmias

scientific article published on 01 August 2005

The multifaceted cardiac sodium channel and its clinical implications

scientific article published on September 2012

The need to continue screening for hypertrophic cardiomyopathy after adolescence

scientific article published on 26 January 2015

The pathophysiological mechanism underlying Brugada syndrome: depolarization versus repolarization

scientific article published on 24 July 2010

The patient with hypertrophic cardiomyopathy has a family ⬇️

scientific article published on 01 February 2011

The phenomenon of "QT stunning": the abnormal QT prolongation provoked by standing persists even as the heart rate returns to normal in patients with long QT syndrome

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The phenotype is equally important in promoting variants from benign to pathogenic as well as in demoting variants from pathogenic to benign

scientific article published on 6 January 2018

The primary arrhythmia syndromes: same mutation, different manifestations. Are we starting to understand why?

scientific article published on 12 February 2008

The relationship between pre-participation screening of young competitive athletes and family screening

scientific article published on 01 June 2009

The response of the QT interval to the brief tachycardia provoked by standing: a bedside test for diagnosing long QT syndrome

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The role of renin-angiotensin-aldosterone system polymorphisms in phenotypic expression of MYBPC3-related hypertrophic cardiomyopathy

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The role of the epinephrine test in the diagnosis and management of children suspected of having congenital long QT syndrome

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The sense and nonsense of direct-to-consumer genetic testing for cardiovascular disease

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The site of origin of torsade de pointes ⬇️

scientific article published on May 10, 2011

The use of genotype-phenotype correlations in mutation analysis for the long QT syndrome

scientific article published in February 2003

The yield of postmortem genetic testing in sudden death cases with structural findings at autopsy

scientific article published on 18 September 2019

The yield of risk stratification for sudden cardiac death in hypertrophic cardiomyopathy myosin-binding protein C gene mutation carriers: focus on predictive screening

scientific article published on 16 December 2009

The β-angle can help guide clinical decisions in the diagnostic work-up of patients suspected of Brugada syndrome: a validation study of the β-angle in determining the outcome of a sodium channel provocation test

scientific article published on 01 December 2021

Therapeutic approach for patients with catecholaminergic polymorphic ventricular tachycardia: state of the art and future developments ⬇️

scientific article published on September 4, 2011

Therapeutic approaches for Long QT syndrome type 3: an update

scientific article published on 01 February 2018

Think twice before you tell

scientific article published on April 2014

Think twice before you tell

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Thoracoscopic Video-Assisted Pulmonary Vein Antrum Isolation, Ganglionated Plexus Ablation, and Periprocedural Confirmation of Ablation Lesions: First Results of a Hybrid Surgical-Electrophysiological Approach for Atrial Fibrillation

scientific article published on 14 April 2011

Time-to-first appropriate shock in patients implanted prophylactically with an implantable cardioverter-defibrillator: data from the Survey on Arrhythmic Events in BRUgada Syndrome (SABRUS)

scientific article published on 01 May 2019

To Add or Not to Add Mitral Valve Surgery to Septal Myectomy in HOCM Patients

scientific article published on 01 May 2017

Transthyretin amyloidosis: a phenocopy of hypertrophic cardiomyopathy

scientific article published on 05 May 2017

Treatment for patients with catecholaminergic polymorphic ventricular tachycardia: are we in need of randomized trials? ⬇️

scientific article published on July 25, 2012

Treatment of Atrial and Ventricular Arrhythmias Through Autonomic Modulation

scientific article published on 24 October 2015

Truncating titin mutations are associated with a mild and treatable form of dilated cardiomyopathy

scientific article

Two siblings with early repolarization syndrome: clinical and genetic characterization by whole-exome sequencing

scientific article published on 16 December 2020

Two-incision technique for implantation of the subcutaneous implantable cardioverter-defibrillator

scientific article published on 21 May 2013

Type 8 long QT syndrome: pathogenic variants in CACNA1C-encoded Cav1.2 cluster in STAC protein binding site

scientific article published on 01 November 2019

Type of SCN5A mutation determines clinical severity and degree of conduction slowing in loss-of-function sodium channelopathies

scientific article published on 11 November 2008

Understanding torsade de pointes: a bridge to tailored drug therapy?

scientific article published on 01 March 2002

Unidentified Candidates for Cardiac Resynchronization Therapy: Guideline Adherence in a Large Academic Outpatient Clinic in the Netherlands ⬇️

scientific article published on October 18, 2012

Unmasking of brugada syndrome by lithium

scientific article

Use of mutant-specific ion channel characteristics for risk stratification of long QT syndrome patients

scientific article published in March 2011

Using registries to predict outcome: the implantable cardioverter-defibrillator in long QT syndrome

scientific article published on 01 February 2019

Value of history-taking in syncope patients: in whom to suspect long QT syndrome?

scientific article published on 29 May 2009

Value of serial heart rate variability measurement for prediction of appropriate ICD discharge in patients with heart failure.

scientific article

Variable Na(v)1.5 protein expression from the wild-type allele correlates with the penetrance of cardiac conduction disease in the Scn5a(+/-) mouse model

scientific article

Variants in the 3' untranslated region of the KCNQ1-encoded Kv7.1 potassium channel modify disease severity in patients with type 1 long QT syndrome in an allele-specific manner

scientific article published on 23 December 2011

Variants in the SCN5A Promoter Associated With Various Arrhythmia Phenotypes

scientific article published on 13 September 2016

Vasovagal syncope or ventricular fibrillation. Your diagnosis better be accurate

scientific article published in August 2007

Ventricular dysfunction in a family with long QT syndrome type 3 ⬇️

scientific article published on April 23, 2013

Ventricular fibrillation in MYH7-related hypertrophic cardiomyopathy before onset of ventricular hypertrophy

scientific article published on 04 May 2009

Ventricular fibrillation with prominent early repolarization associated with a rare variant of KCNJ8/KATP channel

scientific article

Voltage-gated sodium channels: action players with many faces

scientific article published on January 2006

Where do the extras come from?

scientific article published on February 2005

Which patients are not suitable for a subcutaneous ICD: incidence and predictors of failed QRS-T-wave morphology screening

scientific article published on 07 January 2014

Who are the long-QT syndrome patients who receive an implantable cardioverter-defibrillator and what happens to them?: data from the European Long-QT Syndrome Implantable Cardioverter-Defibrillator (LQTS ICD) Registry

scientific article

Why did this patient experience a sudden cardiac arrest? Follow your curiosity!

scientific article published on 25 February 2019

Wide complexes intervening regular sinus rhythm

scientific article published on December 2006

Yield and Pitfalls of Ajmaline Testing in the Evaluation of Unexplained Cardiac Arrest and Sudden Unexplained Death: Single-Center Experience With 482 Families

scientific article published on 28 June 2017

Yield of molecular and clinical testing for arrhythmia syndromes: report of 15 years' experience.

scientific article

Yield of the RYR2 Genetic Test in Suspected Catecholaminergic Polymorphic Ventricular Tachycardia and Implications for Test Interpretation

scientific article published on 01 February 2018

[Premature sudden death--consider serious familial heart rhythm disturbances]

scientific article published on 01 January 2011

[The optimal treatment of chronic heart failure with beta-blockers may be dependent upon the genetic background of the patient]

scientific article published on 01 July 2007

[Thoracoscopic treatment of atrial fibrillation]

scientific article published on 01 January 2012

hiPSC-derived cardiomyocytes from Brugada Syndrome patients without identified mutations do not exhibit clear cellular electrophysiological abnormalities

scientific article published on 03 August 2016

“J-wave syndromes” bring the ATP-sensitive potassium channel back in the spotlight ⬇️

scientific article published on 03 January 2012

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