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List of works by Neil Q McDonald

A genetically-encoded crosslinker screen identifies SERBP1 as a PKCε substrate influencing translation and cell division

scientific article published on 26 November 2021

Adenosine-binding motif mimicry and cellular effects of a thieno[2,3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes

scientific article

Cryo-EM structures of the XPF-ERCC1 endonuclease reveal how DNA-junction engagement disrupts an auto-inhibited conformation

scientific article published on 28 February 2020

Drugging the catalytically inactive state of RET kinase in RET-rearranged tumors.

scientific article published on June 2017

Molecular recognition of the Tes LIM2-3 domains by the actin-related protein Arp7A

scientific article

Oncogenic RET Kinase Domain Mutations Perturb the Autophosphorylation Trajectory by Enhancing Substrate Presentation In trans

scientific article

RET recognition of GDNF-GFRα1 ligand by a composite binding site promotes membrane-proximal self-association

scientific article

RPEL-family rhoGAPs link Rac/Cdc42 GTP loading to G-actin availability

scientific article published on 17 June 2019

Structure and chemical inhibition of the RET tyrosine kinase domain

scientific article

Structure of a conserved dimerization domain within the F-box protein Fbxo7 and the PI31 proteasome inhibitor

scientific article

Synthesis, structure-activity relationship and crystallographic studies of 3-substituted indolin-2-one RET inhibitors

scientific article

The solution structure of the Josephin domain of ataxin-3: structural determinants for molecular recognition

scientific article

Transforming activity of Fbxo7 is mediated specifically through regulation of cyclin D/cdk6.

scientific article

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