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List of works by Guido Bocci

5-fluorouracil pharmacokinetics predicts disease-free survival in patients administered adjuvant chemotherapy for colorectal cancer.

scientific article published in May 2008

A pharmacokinetic-based test to prevent severe 5-fluorouracil toxicity

scientific article published on 01 October 2006

A rapid high-performance liquid chromatography method to measure linezolid and daptomycin concentrations in human plasma

scientific article published in April 2010

All-oral metronomic DEVEC schedule in elderly patients with peripheral T cell lymphoma

scientific article published on 18 October 2020

Antiangiogenic versus cytotoxic therapeutic approaches to human pancreas cancer: an experimental study with a vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor and gemcitabine.

scientific article

CLM94, a novel cyclic amide with anti-VEGFR-2 and antiangiogenic properties, is active against primary anaplastic thyroid cancer in vitro and in vivo.

scientific article published on 25 January 2012

Clinical and pharmacodynamic evaluation of metronomic cyclophosphamide, celecoxib, and dexamethasone in advanced hormone-refractory prostate cancer.

scientific article published on 21 July 2009

Clinical, pharmacodynamic and pharmacokinetic results of a prospective phase II study on oral metronomic vinorelbine and dexamethasone in castration-resistant prostate cancer patients

scientific article published on 24 August 2016

Clinical, pharmacokinetic and pharmacodynamic evaluations of metronomic UFT and cyclophosphamide plus celecoxib in patients with advanced refractory gastrointestinal cancers

scientific article published on 2 March 2012

Dihydropyrimidine dehydrogenase polymorphisms and fluoropyrimidine toxicity: ready for routine clinical application within personalized medicine?

scientific article

Discordant somatic and germlineVEGF-Agenotype in a cancer patient resistant to paclitaxel/bevacizumab with chemosensitive hepatic metastasis

scientific article published on 01 August 2009

Docetaxel plus oral metronomic cyclophosphamide: a phase II study with pharmacodynamic and pharmacogenetic analyses in castration-resistant prostate cancer patients.

scientific article

Drug therapeutic failures in emergency department patients. A university hospital experience.

scientific article published in January 2004

EGFR ligands as pharmacodynamic biomarkers in metastatic colorectal cancer patients treated with cetuximab and irinotecan.

scientific article published on 3 July 2013

First-line metronomic chemotherapy in a metastatic model of spontaneous canine tumours: a pilot study.

scientific article published on 21 April 2011

Genetic interaction of P2X7 receptor and VEGFR-2 polymorphisms identifies a favorable prognostic profile in prostate cancer patients.

scientific article published on 21 August 2015

Improved analysis of 5-Fluorouracil and 5,6-dihydro-5-Fluorouracil by HPLC with diode array detection for determination of cellular dihydropyrimidine dehydrogenase activity and pharmacokinetic profiling

scientific article published in June 2005

In vitro and in vivo antitumour effects of novel, orally active bile acid-conjugated platinum complexes on rat hepatoma

scientific article published on 16 August 2006

Investigation of new 2-aryl substituted Benzothiopyrano[4,3-d]pyrimidines as kinase inhibitors targeting vascular endothelial growth factor receptor 2.

scientific article published on 14 August 2015

Irinotecan in combination with thalidomide in patients with advanced solid tumors: a clinical study with pharmacodynamic and pharmacokinetic evaluation.

scientific article published on 6 May 2006

Irinotecan synergistically enhances the antiproliferative and proapoptotic effects of axitinib in vitro and improves its anticancer activity in vivo

scientific article published on March 2011

Melanocortin Receptor-4 and Glioblastoma Cells: Effects of the Selective Antagonist ML00253764 Alone and in Combination with Temozolomide In Vitro and In Vivo.

scientific article published on 8 August 2017

Methods: for studying pharmacogenetic profiles of combination chemotherapeutic drugs

scientific article published on 03 June 2015

Metronomic 5-fluorouracil, oxaliplatin and irinotecan in colorectal cancer.

scientific article

Metronomic chemotherapy for metastatic prostate cancer: a 'young' concept for old patients?

scientific article published on September 2010

Metronomic cyclophosphamide in elderly patients with advanced, castration-resistant prostate cancer.

scientific article published on May 2010

Novel pyrazolopyrimidine derivatives as tyrosine kinase inhibitors with antitumoral activity in vitro and in vivo in papillary dedifferentiated thyroid cancer.

scientific article published on 8 December 2010

Pan-European Expert Meeting on the Use of Metronomic Chemotherapy in Advanced Breast Cancer Patients: The PENELOPE Project

scientific article published on 18 December 2018

Pharmacogenetic Labyrinth of Neovascular Age-Related Macular Degeneration Therapy: How to Escape and Move Forward? ⬇️

scientific article published on August 1, 2013

Pharmacogenetic interaction analysis of VEGFR-2 and IL-8 polymorphisms in advanced breast cancer patients treated with paclitaxel and bevacizumab.

scientific article published in December 2014

Pharmacokinetic analysis of metronomic capecitabine in refractory metastatic colorectal cancer patients

scientific article published on 27 February 2018

Pharmacokinetic and pharmacogenetic predictive markers of irinotecan activity and toxicity.

scientific article published on December 2011

Pharmacokinetics and pharmacodynamics of combination chemotherapy with paclitaxel and epirubicin in breast cancer patients

scientific article published on May 2002

Pharmacokinetics, a main actor in a many-sided approach to severe 5-FU toxicity prediction

scientific article published on 5 November 2008

Pharmacological effects of the simultaneous and sequential combinations of trifluridine/tipiracil (TAS-102) and 5-fluorouracil in fluoropyrimidine-sensitive colon cancer cells

scientific article published on 01 June 2019

Population pharmacokinetic analysis of 5-FU and 5-FDHU in colorectal cancer patients: search for biomarkers associated with gastro-intestinal toxicity

scientific article published on 01 January 2012

Population pharmacokinetics of daptomycin in patients affected by severe Gram-positive infections.

scientific article published on 25 July 2013

Preclinical and clinical combination therapies in the treatment of anaplastic thyroid cancer

scientific article published on 27 February 2020

Structure-based optimization of tyrosine kinase inhibitor CLM3. Design, synthesis, functional evaluation, and molecular modeling studies

scientific article published on 5 February 2014

The effect of osteogenic growth peptide (OGP) on proliferation and adhesion of HEMC-1 human endothelial cells.

scientific article published on January 2002

Thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase expression in colorectal cancer and normal mucosa in patients

scientific article published on 01 November 2006

Vascular endothelial growth factor levels in immunodepleted plasma of cancer patients as a possible pharmacodynamic marker for bevacizumab activity

scientific article published on 01 May 2007

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