List of works - Lizbeth Hedstrom

A Potent “Fat Base” Nucleotide Inhibitor of IMP Dehydrogenase ⬇️

scientific article published on August 25, 1998

A call to arms: Unifying the fight against resistance

article

A structural determinant of mycophenolic acid resistance in eukaryotic inosine 5'-monophosphate dehydrogenases

scientific article published on 20 November 2019

Allosteric Activation via Kinetic Control: Potassium Accelerates a Conformational Change in IMP Dehydrogenase ⬇️

scientific article published on September 9, 2011

Converting Trypsin to Chymotrypsin: Structural Determinants of S1‘ Specificity ⬇️

scientific article published on August 19, 1997

Converting trypsin to elastase: substitution of the S1 site and adjacent loops reconstitutes esterase specificity but not amidase activity ⬇️

scientific article published on 01 August 1998

Dynamic Characteristics of Guanosine-5'-monophosphate Reductase Complexes Revealed by High-Resolution 31P Field-Cycling NMR Relaxometry.

scientific article published on 16 March 2018

Engineering the S1‘ Subsite of Trypsin: Design of a Protease Which Cleaves between Dibasic Residues ⬇️

scientific article published on August 18, 1998

Enzyme-substrate-cofactor dynamical networks revealed by high resolution field cycling relaxometry

scientific article published on 01 June 2020

Expanding benzoxazole based inosine 5'-monophosphate dehydrogenase (IMPDH) inhibitor structure-activity as potential anti-tuberculosis agents.

scientific article published on 10 May 2018

Expression, Purification, and Characterization of Inosine 5′-Monophosphate Dehydrogenase from Borrelia burgdorferi ⬇️

scientific article published on August 29, 1997

Guanidine derivatives restore activity to carboxypeptidase lacking arginine‐127 ⬇️

scientific article published on April 1, 1992

IMP dehydrogenase: the dynamics of drug selectivity ⬇️

scientific article published on 01 January 2003

Kinetic Mechanism of Human Inosine 5‘-Monophosphate Dehydrogenase Type II: Random Addition of Substrates and Ordered Release of Products ⬇️

scientific article published on July 15, 1997

Multivalent Glycocluster Design through Directed Evolution ⬇️

scientific article published on November 18, 2011

Mushroom Tyrosinase Oxidizes Tyrosine‐Rich Sequences to Allow Selective Protein Functionalization ⬇️

scientific article published on July 17, 2012

Oxanosine Monophosphate Is a Covalent Inhibitor of Inosine 5'-Monophosphate Dehydrogenase

scientific article published on 25 February 2019

Specific biotinylation of IMP dehydrogenase ⬇️

scientific article published on January 14, 2011

Substrate and Cofactor Dynamics on Guanosine Monophosphate Reductase Probed by High Resolution Field Cycling 31P NMR Relaxometry.

scientific article published on 9 September 2016

The Cys319 Loop Modulates the Transition between Dehydrogenase and Hydrolase Conformations in Inosine 5′-Monophosphate Dehydrogenase ⬇️

scientific article published on November 23, 2010

The Roles of Conserved Carboxylate Residues in IMP Dehydrogenase and Identification of a Transition State Analog ⬇️

scientific article published on October 28, 1997

The dynamic determinants of reaction specificity in the IMPDH/GMPR family of (β/α)8barrel enzymes ⬇️

scientific article published on February 15, 2012

Towards a Pathological Mechanism for IMPDH1-Linked Retinitis Pigmentosa ⬇️

scientific article published on January 1, 2012

List of works by Lizbeth Hedstrom