List of works by Christoph Plass

A leukemia-protective germline variant mediates chromatin module formation via transcription factor nucleation

scientific article published on 19 April 2022

Aberrant DNA methylation characterizes juvenile myelomonocytic leukemia with poor outcome.

scientific article

Azacitidine is effective for targeting leukemia-initiating cells in juvenile myelomonocytic leukemia

scientific article published on 24 January 2019

Cadherin-6 is a putative tumor suppressor and target of epigenetically dysregulated miR-429 in cholangiocarcinoma

scientific article published on 03 September 2016

Cancer cell specific inhibition of Wnt/β-catenin signaling by forced intracellular acidification.

scientific article

Combination treatment of acute myeloid leukemia cells with DNMT and HDAC inhibitors: predominant synergistic gene downregulation associated with gene body demethylation

scientific article published on 23 November 2018

Corrigendum: Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

scientific article published in Nature

DNA methylation signatures of monozygotic twins clinically discordant for multiple sclerosis

scientific article published on 07 May 2019

DNMT and HDAC inhibitors induce cryptic transcription start sites encoded in long terminal repeats.

scientific article

Decitabine induces gene derepression on monosomic chromosomes: in vitro and in vivo effects in adverse-risk cytogenetics AML

scientific article published on 17 November 2020

Differential expression of the tumor suppressor A-kinase anchor protein 12 in human diffuse and pilocytic astrocytomas is regulated by promoter methylation

scientific article published in October 2013

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

scientific article (publication date: 29 January 2012)

Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia

scientific article

Epigenetic regulation of diacylglycerol kinase alpha promotes radiation-induced fibrosis

scientific article published on 11 March 2016

Epigenetic reprogramming of airway macrophages promotes polarization and inflammation in muco-obstructive lung disease

scientific article published on 11 November 2021

Epigenetics meets genetics in acute myeloid leukemia: clinical impact of a novel seven-gene score

scientific article published on 30 December 2013

Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia

scientific article

Extensive promoter DNA hypermethylation and hypomethylation is associated with aberrant microRNA expression in chronic lymphocytic leukemia

scientific article

Genome-wide screen for differentially methylated long noncoding RNAs identifies Esrp2 and lncRNA Esrp2-as regulated by enhancer DNA methylation with prognostic relevance for human breast cancer

scientific article

Global alterations of DNA methylation in cholangiocarcinoma target the Wnt signaling pathway

scientific article published on 24 December 2013

Global assessment of promoter methylation in a mouse model of cancer identifies ID4 as a putative tumor-suppressor gene in human leukemia

scientific article

Globally altered epigenetic landscape and delayed osteogenic differentiation in H3.3-G34W-mutant giant cell tumor of bone

scientific article published on 27 October 2020

Histone 3.3 hotspot mutations in conventional osteosarcomas: a comprehensive clinical and molecular characterization of six H3F3A mutated cases

scientific article

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma

scientific article published in October 2012

Hypermutation of the inactive X chromosome is a frequent event in cancer

scientific article published on 17 October 2013

IL-10 production by CLL cells is enhanced in the anergic IGHV mutated subset and associates with reduced DNA methylation of the IL10 locus

scientific article published on 28 November 2016

INFORM2 NivEnt: The first trial of the INFORM2 biomarker driven phase I/II trial series: the combination of nivolumab and entinostat in children and adolescents with refractory high-risk malignancies

scientific article published on 05 June 2020

Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer

scientific article

International consensus definition of DNA methylation subgroups in juvenile myelomonocytic leukemia

scientific article published on 02 November 2020

Interplay of RUNX1/MTG8 and DNA methyltransferase 1 in acute myeloid leukemia.

scientific article published on February 2005

MGMT testing--the challenges for biomarker-based glioma treatment

scientific article

Malignant astrocytomas of elderly patients lack favorable molecular markers: an analysis of the NOA-08 study collective

scientific article published on 17 April 2013

Molecular Evolution of Early-Onset Prostate Cancer Identifies Molecular Risk Markers and Clinical Trajectories

scientific article published on 01 December 2018

Overexpression of the chromatin remodeler death-domain-associated protein in prostate cancer is an independent predictor of early prostate-specific antigen recurrence

scientific article published on 2 May 2013

Phase I study of decitabine alone or in combination with valproic acid in acute myeloid leukemia

scientific article

Phase I trial of low dose decitabine targeting DNA hypermethylation in patients with chronic lymphocytic leukaemia and non-Hodgkin lymphoma: dose-limiting myelosuppression without evidence of DNA hypomethylation

scientific article

Prognostic relevance of miRNA-155 methylation in anaplastic glioma

scientific article published on 18 November 2016

Quantitative DNA methylation analysis identifies a single CpG dinucleotide important for ZAP-70 expression and predictive of prognosis in chronic lymphocytic leukemia

scientific article

Quantitative analyses of DAPK1 methylation in AML and MDS

scientific article

RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia.

scientific article published on 19 December 2017

RASA4 undergoes DNA hypermethylation in resistant juvenile myelomonocytic leukemia

scientific article

Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas

scientific article

Reference-free deconvolution, visualization and interpretation of complex DNA methylation data using DecompPipeline, MeDeCom and FactorViz

scientific article published on 25 September 2020

TMPRSS2-ERG fusions are strongly linked to young patient age in low-grade prostate cancer.

scientific article published on 9 July 2014

Validation of ZAP-70 methylation and its relative significance in predicting outcome in chronic lymphocytic leukemia

scientific article

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