List of works - James R Eshleman

A combination of molecular markers and clinical features improve the classification of pancreatic cysts

scientific article

A novel approach for selecting combination clinical markers of pathology applied to a large retrospective cohort of surgically resected pancreatic cysts

scientific article published on 21 June 2016

ATM mutations in patients with hereditary pancreatic cancer

scientific article published on 29 December 2011

Alterations of type II classical cadherin, cadherin-10 (CDH10), is associated with pancreatic ductal adenocarcinomas

scientific article published on 25 January 2017

An in vivo platform for translational drug development in pancreatic cancer

scientific article published on 01 August 2006

Circulating Tumor DNA as a Clinical Test in Resected Pancreatic Cancer

scientific article published on 29 May 2019

Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients

scientific article

Clinicopathological characteristics and molecular analyses of multifocal intraductal papillary mucinous neoplasms of the pancreas

scientific article

Clinicopathological correlates of activating GNAS mutations in intraductal papillary mucinous neoplasm (IPMN) of the pancreas

scientific article published on 12 July 2013

Comparison of LigAmp and an ASPCR assay for detection and quantification of K103N-containing HIV variants

scientific article

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

scientific article

DETECTION OF CIRCULATING TUMOR DNA IN PATIENTS WITH PANCREATIC CANCER USING DIGITAL NEXT-GENERATION SEQUENCING

scientific article published on 20 March 2020

DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer.

scientific article published on 10 April 2009

Differentiating pancreatic lesions by microarray and QPCR analysis of pancreatic juice RNAs.

scientific article

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

scientific article

Epigenetic inactivation of TFPI-2 as a common mechanism associated with growth and invasion of pancreatic ductal adenocarcinoma.

scientific article

Evaluation of DNA from the Papanicolaou test to detect ovarian and endometrial cancers

scientific article

Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene

scientific article

Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays

scientific article (publication date: April 2003)

Familial and sporadic pancreatic cancer share the same molecular pathogenesis

scientific article

Familial pancreatic cancer: from genes to improved patient care

scientific article published on October 2007

GNAS codon 201 mutations are uncommon in intraductal papillary neoplasms of the bile duct

scientific article

Gene Variants That Affect Levels of Circulating Tumor Markers Increase Identification of Patients With Pancreatic Cancer

scientific article published on 30 October 2019

Genetic and epigenetic alterations of familial pancreatic cancers

scientific article published on December 2008

Genetic mutations associated with cigarette smoking in pancreatic cancer

scientific article

Genetically defined subsets of human pancreatic cancer show unique in vitro chemosensitivity

scientific article

International network of cancer genome projects

scientific article

KRAS and guanine nucleotide-binding protein mutations in pancreatic juice collected from the duodenum of patients at high risk for neoplasia undergoing endoscopic ultrasound

scientific article

KRAS2 mutations in human pancreatic acinar-ductal metaplastic lesions are limited to those with PanIN: implications for the human pancreatic cancer cell of origin

scientific article

LigAmp for sensitive detection of single-nucleotide differences.

scientific article

Loss of expression of the SWI/SNF chromatin remodeling subunit BRG1/SMARCA4 is frequently observed in intraductal papillary mucinous neoplasms of the pancreas

scientific article published on 21 September 2011

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade.

scientific article

Molecular characterization of organoids derived from pancreatic intraductal papillary mucinous neoplasms

scientific article published on 22 July 2020

Mutant GNAS detected in duodenal collections of secretin-stimulated pancreatic juice indicates the presence or emergence of pancreatic cysts

scientific article published on 02 August 2012

Mutant proteins as cancer-specific biomarkers

scientific article

Mutations in the pancreatic secretory enzymes CPA1 and CPB1 are associated with pancreatic cancer.

scientific article published on 18 April 2018

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

scientific article

Palladin is overexpressed in the non-neoplastic stroma of infiltrating ductal adenocarcinomas of the pancreas, but is only rarely overexpressed in neoplastic cells

scientific article

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

scientific article

Personalized chemotherapy profiling using cancer cell lines from selectable mice

scientific article

Personalizing cancer treatment in the age of global genomic analyses: PALB2 gene mutations and the response to DNA damaging agents in pancreatic cancer

scientific article

Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development

scientific article

SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer

scientific article

Sensitive and quantitative detection of KRAS2 gene mutations in pancreatic duct juice differentiates patients with pancreatic cancer from chronic pancreatitis, potential for early detection

scientific article published on 01 March 2008

Sensitivity of the ViroSeq HIV-1 genotyping system for detection of the K103N resistance mutation in HIV-1 subtypes A, C, and D.

scientific article published on September 2006

Simple Detection of Telomere Fusions in Pancreatic Cancer, Intraductal Papillary Mucinous Neoplasm, and Pancreatic Cyst Fluid

scientific article published on 6 December 2017

Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types

scientific article

Telomeres are shortened in acinar-to-ductal metaplasia lesions associated with pancreatic intraepithelial neoplasia but not in isolated acinar-to-ductal metaplasias.

scientific article

Transflip mutations produce deletions in pancreatic cancer

scientific article published on 29 May 2015

Validation Strategy for Ultrasensitive Mutation Detection

scientific article published on 01 October 2018

Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer

scientific article published on 9 December 2015

Whole genomes redefine the mutational landscape of pancreatic cancer

scientific article published in February 2015

Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways

scientific article published on 8 December 2011

Whole-exome sequencing of pancreatic neoplasms with acinar differentiation

scientific article

List of works by James R Eshleman

A combination of molecular markers and clinical features improve the classification of pancreatic cysts

A novel approach for selecting combination clinical markers of pathology applied to a large retrospective cohort of surgically resected pancreatic cysts

ATM mutations in patients with hereditary pancreatic cancer

Alterations of type II classical cadherin, cadherin-10 (CDH10), is associated with pancreatic ductal adenocarcinomas

An in vivo platform for translational drug development in pancreatic cancer

Circulating Tumor DNA as a Clinical Test in Resected Pancreatic Cancer

Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients

Clinicopathological characteristics and molecular analyses of multifocal intraductal papillary mucinous neoplasms of the pancreas

Clinicopathological correlates of activating GNAS mutations in intraductal papillary mucinous neoplasm (IPMN) of the pancreas

Comparison of LigAmp and an ASPCR assay for detection and quantification of K103N-containing HIV variants

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

DETECTION OF CIRCULATING TUMOR DNA IN PATIENTS WITH PANCREATIC CANCER USING DIGITAL NEXT-GENERATION SEQUENCING

DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer.

Differentiating pancreatic lesions by microarray and QPCR analysis of pancreatic juice RNAs.

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

Epigenetic inactivation of TFPI-2 as a common mechanism associated with growth and invasion of pancreatic ductal adenocarcinoma.

Evaluation of DNA from the Papanicolaou test to detect ovarian and endometrial cancers

Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene

Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays

Familial and sporadic pancreatic cancer share the same molecular pathogenesis

Familial pancreatic cancer: from genes to improved patient care

GNAS codon 201 mutations are uncommon in intraductal papillary neoplasms of the bile duct

Gene Variants That Affect Levels of Circulating Tumor Markers Increase Identification of Patients With Pancreatic Cancer

Genetic and epigenetic alterations of familial pancreatic cancers

Genetic mutations associated with cigarette smoking in pancreatic cancer

Genetically defined subsets of human pancreatic cancer show unique in vitro chemosensitivity

International network of cancer genome projects

KRAS and guanine nucleotide-binding protein mutations in pancreatic juice collected from the duodenum of patients at high risk for neoplasia undergoing endoscopic ultrasound

KRAS2 mutations in human pancreatic acinar-ductal metaplastic lesions are limited to those with PanIN: implications for the human pancreatic cancer cell of origin

LigAmp for sensitive detection of single-nucleotide differences.

Loss of expression of the SWI/SNF chromatin remodeling subunit BRG1/SMARCA4 is frequently observed in intraductal papillary mucinous neoplasms of the pancreas

Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade.

Molecular characterization of organoids derived from pancreatic intraductal papillary mucinous neoplasms

Mutant GNAS detected in duodenal collections of secretin-stimulated pancreatic juice indicates the presence or emergence of pancreatic cysts

Mutant proteins as cancer-specific biomarkers

Mutations in the pancreatic secretory enzymes CPA1 and CPB1 are associated with pancreatic cancer.

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

Palladin is overexpressed in the non-neoplastic stroma of infiltrating ductal adenocarcinomas of the pancreas, but is only rarely overexpressed in neoplastic cells

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

Personalized chemotherapy profiling using cancer cell lines from selectable mice

Personalizing cancer treatment in the age of global genomic analyses: PALB2 gene mutations and the response to DNA damaging agents in pancreatic cancer

Recurrent GNAS mutations define an unexpected pathway for pancreatic cyst development

SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer

Sensitive and quantitative detection of KRAS2 gene mutations in pancreatic duct juice differentiates patients with pancreatic cancer from chronic pancreatitis, potential for early detection

Sensitivity of the ViroSeq HIV-1 genotyping system for detection of the K103N resistance mutation in HIV-1 subtypes A, C, and D.

Simple Detection of Telomere Fusions in Pancreatic Cancer, Intraductal Papillary Mucinous Neoplasm, and Pancreatic Cyst Fluid

Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types

Telomeres are shortened in acinar-to-ductal metaplasia lesions associated with pancreatic intraepithelial neoplasia but not in isolated acinar-to-ductal metaplasias.

Transflip mutations produce deletions in pancreatic cancer

Validation Strategy for Ultrasensitive Mutation Detection

Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer

Whole genomes redefine the mutational landscape of pancreatic cancer

Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways

Whole-exome sequencing of pancreatic neoplasms with acinar differentiation