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List of works by Indu S Ambudkar

Activation of TRPC1 by STIM1 in ER-PM microdomains involves release of the channel from its scaffold caveolin-1.

scientific article

Active secretion and protective effect of salivary nitrate against stress in human volunteers and rats ⬇️

scientific article published on December 28, 2012

Apical localization of a functional TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells. Role in apical Ca2+ influx

scientific article

Association of bone morphogenetic protein 6 with exocrine gland dysfunction in patients with Sjögren's syndrome and in mice

scientific article published in December 2013

Attenuation of store-operated Ca2+ current impairs salivary gland fluid secretion in TRPC1(-/-) mice

scientific journal article

Biogenesis and topology of the transient receptor potential Ca2+ channel TRPC1.

scientific article

Ca2+ signaling microdomains:platforms for the assembly and regulation of TRPC channels

scientific article

Caveolin-1 contributes to assembly of store-operated Ca2+ influx channels by regulating plasma membrane localization of TRPC1.

scientific article published on 5 May 2003

Ca²⁺ signaling and regulation of fluid secretion in salivary gland acinar cells

scientific article

Cellular domains that contribute to Ca2+ entry events

scientific article published on 20 July 2004

Conditional overexpression of TGF-beta1 disrupts mouse salivary gland development and function

scientific article

Depletion of intracellular Ca2+ stores stimulates the translocation of vanilloid transient receptor potential 4-c1 heteromeric channels to the plasma membrane

scientific article published on 12 August 2010

Diacylglycerols activate mitochondrial cationic channel(s) and release sequestered Ca(2+).

scientific article published on August 2005

Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx. Evidence for similarities in store-operated and calcium release-activated calcium channel components

scientific article

Extracellular Ca(2+) sensing in salivary ductal cells.

scientific article

Functional organization of TRPC-Ca2+ channels and regulation of calcium microdomains

scientific article published on 9 October 2006

Functional requirement for Orai1 in store-operated TRPC1-STIM1 channels

scientific article

Heteromeric TRPV4-C1 channels contribute to store-operated Ca2+ entry in vascular endothelial cells ⬇️

scientific article published on September 18, 2011

Hydrogen sulfide maintains mesenchymal stem cell function and bone homeostasis via regulation of Ca(2+) channel sulfhydration

scientific article

IP3R deficit underlies loss of salivary fluid secretion in Sjögren's Syndrome

scientific article

Impairment of TRPC1-STIM1 channel assembly and AQP5 translocation compromise agonist-stimulated fluid secretion in mice lacking caveolin1

scientific article published on 30 November 2012

Lipid rafts determine clustering of STIM1 in endoplasmic reticulum-plasma membrane junctions and regulation of store-operated Ca2+ entry (SOCE)

scientific article published on 22 April 2008

Local Ca2+ Entry Via Orai1 Regulates Plasma Membrane Recruitment of TRPC1 and Controls Cytosolic Ca2+ Signals Required for Specific Cell Functions ⬇️

scientific article published on March 8, 2011

Loss of TRPC1-mediated Ca2+ influx contributes to impaired degranulation in Fyn-deficient mouse bone marrow-derived mast cells

scientific article

Loss of TRPM2 function protects against irradiation-induced salivary gland dysfunction ⬇️

scientific article published on January 1, 2013

Matriptase deletion initiates a Sjögren's syndrome-like disease in mice

scientific article

Organization and function of TRPC channelosomes

scientific article published on 8 May 2007

Plasma membrane localization of TRPC channels: role of caveolar lipid rafts

scientific article published on January 2004

Polarized but differential localization and recruitment of STIM1, Orai1 and TRPC channels in secretory cells.

scientific article

RACK1 plays a critical role in mast cell secretion and Ca2+ mobilization by modulating F-actin dynamics

scientific article published on 13 May 2021

Radiation inhibits salivary gland function by promoting STIM1 cleavage by caspase-3 and loss of SOCE through a TRPM2-dependent pathway.

scientific article

Relocalization of STIM1 for activation of store-operated Ca(2+) entry is determined by the depletion of subplasma membrane endoplasmic reticulum Ca(2+) store

scientific article published on 12 February 2007

Revealing the fate of cell surface human P-glycoprotein (ABCB1): The lysosomal degradation pathway.

scientific article

STIM1 and STIM2 protein deficiency in T lymphocytes underlies development of the exocrine gland autoimmune disease, Sjögren's syndrome ⬇️

scientific article published on August 17, 2012

STIM2 enhances receptor-stimulated Ca²⁺ signaling by promoting recruitment of STIM1 to the endoplasmic reticulum-plasma membrane junctions.

scientific article

STIM2 targets Orai1/STIM1 to the AKAP79 signaling complex and confers coupling of Ca2+ entry with NFAT1 activation

scientific article published on 29 June 2020

Sialin ( SLC17A5 ) functions as a nitrate transporter in the plasma membrane ⬇️

scientific article published on July 9, 2012

Store-operated Ca2+ entry is remodelled and controls in vitro angiogenesis in endothelial progenitor cells isolated from tumoral patients

scientific article

TRPC1 participates in the HSV-1 infection process by facilitating viral entry

scientific article published on 18 March 2020

TRPC1: getting physical in space

scientific article published on 27 September 2013

TRPC1: the link between functionally distinct store-operated calcium channels

scientific article published on 12 March 2007

TRPC3 controls agonist-stimulated intracellular Ca2+ release by mediating the interaction between inositol 1,4,5-trisphosphate receptor and RACK1.

scientific article published on 28 August 2008

Targeting the Ca(2+) Sensor STIM1 by Exosomal Transfer of Ebv-miR-BART13-3p is Associated with Sjögren's Syndrome

scientific article published on 29 June 2016

The adapter molecule Gab2 regulates Fc epsilon RI-mediated signal transduction in mast cells

scientific journal article

The dynamic complexity of the TRPC1 channelosome ⬇️

scientific article published on September 1, 2011

Tumor necrosis factor induces apoptosis in hepatoma cells by increasing Ca(2+) release from the endoplasmic reticulum and suppressing Bcl-2 expression

scientific journal article

Up-regulation of Store-operated Ca2+ Entry and Nuclear Factor of Activated T Cells Promote the Acinar Phenotype of the Primary Human Salivary Gland Cells

scientific article published on 22 February 2016

Up-regulation of transient receptor potential canonical 1 (TRPC1) following sarco(endo)plasmic reticulum Ca2+ ATPase 2 gene silencing promotes cell survival: a potential role for TRPC1 in Darier's disease.

scientific article

VAMP2-dependent exocytosis regulates plasma membrane insertion of TRPC3 channels and contributes to agonist-stimulated Ca2+ influx

scientific article

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