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List of works by Indu S Ambudkar

Activation of TRPC1 by STIM1 in ER-PM microdomains involves release of the channel from its scaffold caveolin-1.

scientific article

Active secretion and protective effect of salivary nitrate against stress in human volunteers and rats

scientific article published on December 28, 2012

Apical localization of a functional TRPC3/TRPC6-Ca2+-signaling complex in polarized epithelial cells. Role in apical Ca2+ influx

scientific article

Association of bone morphogenetic protein 6 with exocrine gland dysfunction in patients with Sjögren's syndrome and in mice

scientific article published in December 2013

Attenuation of store-operated Ca2+ current impairs salivary gland fluid secretion in TRPC1(-/-) mice

scientific journal article

Biogenesis and topology of the transient receptor potential Ca2+ channel TRPC1.

scientific article

Ca2+ signaling microdomains:platforms for the assembly and regulation of TRPC channels

scientific article

Caveolin-1 contributes to assembly of store-operated Ca2+ influx channels by regulating plasma membrane localization of TRPC1.

scientific article published on 5 May 2003

Ca²⁺ signaling and regulation of fluid secretion in salivary gland acinar cells

scientific article

Cellular domains that contribute to Ca2+ entry events

scientific article published on 20 July 2004

Conditional overexpression of TGF-beta1 disrupts mouse salivary gland development and function

scientific article

Depletion of intracellular Ca2+ stores stimulates the translocation of vanilloid transient receptor potential 4-c1 heteromeric channels to the plasma membrane

scientific article published on 12 August 2010

Diacylglycerols activate mitochondrial cationic channel(s) and release sequestered Ca(2+).

scientific article published on August 2005

Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx. Evidence for similarities in store-operated and calcium release-activated calcium channel components

scientific article

Extracellular Ca(2+) sensing in salivary ductal cells.

scientific article

Functional organization of TRPC-Ca2+ channels and regulation of calcium microdomains

scientific article published on 9 October 2006

Functional requirement for Orai1 in store-operated TRPC1-STIM1 channels

scientific article

Heteromeric TRPV4-C1 channels contribute to store-operated Ca2+ entry in vascular endothelial cells

scientific article published on September 18, 2011

Hydrogen sulfide maintains mesenchymal stem cell function and bone homeostasis via regulation of Ca(2+) channel sulfhydration

scientific article

IP3R deficit underlies loss of salivary fluid secretion in Sjögren's Syndrome

scientific article

Impairment of TRPC1-STIM1 channel assembly and AQP5 translocation compromise agonist-stimulated fluid secretion in mice lacking caveolin1

scientific article published on 30 November 2012

Lipid rafts determine clustering of STIM1 in endoplasmic reticulum-plasma membrane junctions and regulation of store-operated Ca2+ entry (SOCE)

scientific article published on 22 April 2008

Local Ca2+ Entry Via Orai1 Regulates Plasma Membrane Recruitment of TRPC1 and Controls Cytosolic Ca2+ Signals Required for Specific Cell Functions

scientific article published on March 8, 2011

Loss of TRPC1-mediated Ca2+ influx contributes to impaired degranulation in Fyn-deficient mouse bone marrow-derived mast cells

scientific article

Loss of TRPM2 function protects against irradiation-induced salivary gland dysfunction

scientific article published on January 1, 2013

Matriptase deletion initiates a Sjögren's syndrome-like disease in mice

scientific article

Organization and function of TRPC channelosomes

scientific article published on 8 May 2007

Plasma membrane localization of TRPC channels: role of caveolar lipid rafts

scientific article published on January 2004

Polarized but differential localization and recruitment of STIM1, Orai1 and TRPC channels in secretory cells.

scientific article

RACK1 plays a critical role in mast cell secretion and Ca2+ mobilization by modulating F-actin dynamics

scientific article published on 13 May 2021

Radiation inhibits salivary gland function by promoting STIM1 cleavage by caspase-3 and loss of SOCE through a TRPM2-dependent pathway.

scientific article

Relocalization of STIM1 for activation of store-operated Ca(2+) entry is determined by the depletion of subplasma membrane endoplasmic reticulum Ca(2+) store

scientific article published on 12 February 2007

Revealing the fate of cell surface human P-glycoprotein (ABCB1): The lysosomal degradation pathway.

scientific article

STIM1 and STIM2 protein deficiency in T lymphocytes underlies development of the exocrine gland autoimmune disease, Sjögren's syndrome

scientific article published on August 17, 2012

STIM2 enhances receptor-stimulated Ca²⁺ signaling by promoting recruitment of STIM1 to the endoplasmic reticulum-plasma membrane junctions.

scientific article

STIM2 targets Orai1/STIM1 to the AKAP79 signaling complex and confers coupling of Ca2+ entry with NFAT1 activation

scientific article published on 29 June 2020

Sialin ( SLC17A5 ) functions as a nitrate transporter in the plasma membrane

scientific article published on July 9, 2012

Store-operated Ca2+ entry is remodelled and controls in vitro angiogenesis in endothelial progenitor cells isolated from tumoral patients

scientific article

TRPC1 participates in the HSV-1 infection process by facilitating viral entry

scientific article published on 18 March 2020

TRPC1: getting physical in space

scientific article published on 27 September 2013

TRPC1: the link between functionally distinct store-operated calcium channels

scientific article published on 12 March 2007

TRPC3 controls agonist-stimulated intracellular Ca2+ release by mediating the interaction between inositol 1,4,5-trisphosphate receptor and RACK1.

scientific article published on 28 August 2008

Targeting the Ca(2+) Sensor STIM1 by Exosomal Transfer of Ebv-miR-BART13-3p is Associated with Sjögren's Syndrome

scientific article published on 29 June 2016

The adapter molecule Gab2 regulates Fc epsilon RI-mediated signal transduction in mast cells

scientific journal article

The dynamic complexity of the TRPC1 channelosome

scientific article published on September 1, 2011

Tumor necrosis factor induces apoptosis in hepatoma cells by increasing Ca(2+) release from the endoplasmic reticulum and suppressing Bcl-2 expression

scientific journal article

Up-regulation of Store-operated Ca2+ Entry and Nuclear Factor of Activated T Cells Promote the Acinar Phenotype of the Primary Human Salivary Gland Cells

scientific article published on 22 February 2016

Up-regulation of transient receptor potential canonical 1 (TRPC1) following sarco(endo)plasmic reticulum Ca2+ ATPase 2 gene silencing promotes cell survival: a potential role for TRPC1 in Darier's disease.

scientific article

VAMP2-dependent exocytosis regulates plasma membrane insertion of TRPC3 channels and contributes to agonist-stimulated Ca2+ influx

scientific article