List of works - Chelsea Mayoh

A Novel Orthotopic Patient-Derived Xenograft Model of Radiation-Induced Glioma Following Medulloblastoma

scientific article published on 12 October 2020

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

scientific article published on 22 January 2019

A risk score including microdeletions improves relapse prediction for standard and medium risk precursor B-cell acute lymphoblastic leukaemia in children.

scientific article published on 30 November 2017

An ALYREF-MYCN coactivator complex drives neuroblastoma tumorigenesis through effects on USP3 and MYCN stability

scientific article published on 25 March 2021

Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma

scientific article published on 17 September 2018

CCI-007, a novel small molecule with cytotoxic activity against infant leukemia with MLL rearrangements.

scientific article

Delineation of the frequency and boundary of chromosomal copy number variations in paediatric neuroblastoma.

scientific article published on 22 January 2018

Divergent clonal selection dominates medulloblastoma at recurrence

scientific article published on 13 January 2016

Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface

scientific article published on 09 September 2019

Effective targeting of NAMPT in patient-derived xenograft models of high-risk pediatric acute lymphoblastic leukemia

scientific article published on 17 December 2019

Efficacy of MEK inhibition in a recurrent malignant peripheral nerve sheath tumor

publication published on 12 February 2021

Genome-Wide Association Meta-Analysis of Single-Nucleotide Polymorphisms and Symptomatic Venous Thromboembolism during Therapy for Acute Lymphoblastic Leukemia and Lymphoma in Caucasian Children

scientific article published on 19 May 2020

Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design

scientific article published on 01 November 2019

Glutamine addiction promotes glucose oxidation in triple-negative breast cancer

scientific article published on 18 July 2022

Inhibition of polyamine synthesis and uptake reduces tumor progression and prolongs survival in mouse models of neuroblastoma

scientific article published on 01 January 2019

Intra-tumoral copper modulates PD-L1 expression and influences tumor immune evasion

scientific article published on 18 August 2020

JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma

scientific article published on 25 July 2019

Network modeling of microRNA-mRNA interactions in neuroblastoma tumorigenesis identifies miR-204 as a direct inhibitor of MYCN.

scientific article published on 2 April 2018

OBI-3424, a Novel AKR1C3-Activated Prodrug, Exhibits Potent Efficacy against Preclinical Models of T-ALL

scientific article published on 23 April 2019

Potent antileukemic activity of curaxin CBL0137 against MLL-rearranged leukemia

scientific article published on 08 August 2019

Preclinical activity of the antibody-drug conjugate denintuzumab mafodotin (SGN-CD19A) against pediatric acute lymphoblastic leukemia xenografts

scientific article published on 23 April 2019

Recurrent SPECC1L-NTRK fusions in paediatric sarcoma and brain tumours

scientific article published on 03 November 2020

Spatial heterogeneity in medulloblastoma

scientific article published on 10 April 2017

Suppression of ABCE1-mediated mRNA translation limits N-MYC-driven cancer progression

scientific article published on 10 July 2020

Targeted therapy of <i>TERT</i>-rearranged neuroblastoma with BET bromodomain inhibitor and proteasome inhibitor combination therapy

scientific article published on 11 December 2020

Targeting TSLP-induced tyrosine kinase signaling pathways in CRLF2-rearranged Ph-like ALL

scientific article published on 14 August 2020

The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35

scientific article published on 05 November 2019

Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer

scientific article published on 05 October 2020

List of works by Chelsea Mayoh