List of works - Igor P Pogribny

An in vitro investigation of metabolically sensitive biomarkers in breast cancer progression

scientific article

Cerebellar oxidative DNA damage and altered DNA methylation in the BTBR T+tf/J mouse model of autism and similarities with human post mortem cerebellum

scientific article

Chronic administration of 2-acetylaminofluorene alters the cellular iron metabolism in rat liver

scientific article

Coupling global methylation and gene expression profiles reveal key pathophysiological events in liver injury induced by a methyl-deficient diet

scientific article published on 11 October 2010

Dietary methyl deficiency, microRNA expression and susceptibility to liver carcinogenesis

scientific article

Dietary methyl deficiency, microRNA expression and susceptibility to liver carcinogenesis

Difference in expression of hepatic microRNAs miR-29c, miR-34a, miR-155, and miR-200b is associated with strain-specific susceptibility to dietary nonalcoholic steatohepatitis in mice

scientific journal article

Differential expression of microRNAs during hepatocarcinogenesis induced by methyl deficiency in rats

scientific article published on August 2008

Differentially expressed MicroRNAs provide mechanistic insight into fibrosis-associated liver carcinogenesis in mice

scientific article

Down-regulation of the microRNAs miR-34a, miR-127, and miR-200b in rat liver during hepatocarcinogenesis induced by a methyl-deficient diet

scientific article

E-cadherin transcriptional down-regulation by epigenetic and microRNA-200 family alterations is related to mesenchymal and drug-resistant phenotypes in human breast cancer cells

scientific article

Effect of an obesogenic high-fat and high-sucrose diet on hepatic gene expression signatures in male Collaborative Cross mice

scientific article published in 2023

Effect of long-term tamoxifen exposure on genotoxic and epigenetic changes in rat liver: implications for tamoxifen-induced hepatocarcinogenesis

scientific journal article

Effect of methionine-deficient and methionine-supplemented diets on the hepatic one-carbon and lipid metabolism in mice

scientific article published on 15 May 2014

Epigenetic alterations in liver of C57BL/6J mice after short-term inhalational exposure to 1,3-butadiene

scientific article

Epigenetic effects of low-level sodium arsenite exposure on human liver HepaRG cells

scientific article published on 25 August 2020

Epigenetic reprogramming of liver cells in tamoxifen-induced rat hepatocarcinogenesis

scientific article published in March 2007

Furan-induced transcriptomic and gene-specific DNA methylation changes in the livers of Fischer 344 rats in a 2-year carcinogenicity study

scientific article published on 7 July 2016

Gene expression and cytosine DNA methylation alterations in induced pluripotent stem-cell-derived human hepatocytes treated with low doses of chemical carcinogens

scientific article published on 25 September 2019

Gene expression profiling reveals underlying molecular mechanisms of the early stages of tamoxifen-induced rat hepatocarcinogenesis

scientific article published on 14 July 2007

Genetic and epigenetic changes in fibrosis-associated hepatocarcinogenesis in mice

scientific article

Genotoxic and Epigenotoxic Alterations in the Lung and Liver of Mice Induced by Acrylamide: A 28 Day Drinking Water Study

scientific article published on 12 March 2019

Genotoxic, epigenetic, and transcriptomic effects of tamoxifen in mouse liver

scientific article published on 12 August 2014

Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet

scientific article published on 03 May 2009

Identification of chromatin-accessible domains in non-alcoholic steatohepatitis-derived hepatocellular carcinoma

scientific article published on 16 April 2018

Induction of microRNAome deregulation in rat liver by long-term tamoxifen exposure

scientific article published on 04 February 2007

Interstrain differences in the progression of nonalcoholic steatohepatitis to fibrosis in mice are associated with altered hepatic iron metabolism

scientific article published on 19 August 2014

Interstrain differences in the severity of liver injury induced by a choline- and folate-deficient diet in mice are associated with dysregulation of genes involved in lipid metabolism

scientific article

Iron metabolism disturbances in the MCF-7 human breast cancer cells with acquired resistance to doxorubicin and cisplatin

scientific article

Irreversible down-regulation of miR-375 in the livers of Fischer 344 rats after chronic furan exposure

scientific article published on 28 June 2016

Mechanisms of epigenetic silencing of the Rassf1a gene during estrogen-induced breast carcinogenesis in ACI rats

scientific article

MicroRNA Responses to the Genotoxic Carcinogens Aflatoxin B1 and Benzo[a]pyrene in Human HepaRG Cells

scientific article published on 24 November 2015

MicroRNA changes, activation of progenitor cells and severity of liver injury in mice induced by choline and folate deficiency

scientific article published on 21 October 2015

MicroRNA-152-mediated dysregulation of hepatic transferrin receptor 1 in liver carcinogenesis

scientific article published on 19 October 2015

Modifying metabolically sensitive histone marks by inhibiting glutamine metabolism affects gene expression and alters cancer cell phenotype

scientific article

Modulation of intracellular iron metabolism by iron chelation affects chromatin remodeling proteins and corresponding epigenetic modifications in breast cancer cells and increases their sensitivity to chemotherapeutic agents

scientific article published on 12 March 2013

Persistence of furan-induced epigenetic aberrations in the livers of F344 rats.

scientific article

Plasma microRNAs are sensitive indicators of inter-strain differences in the severity of liver injury induced in mice by a choline- and folate-deficient diet

scientific article

Population-Based Analysis of DNA Damage and Epigenetic Effects of 1,3-Butadiene in the Mouse

scientific article published on 25 April 2019

Role of ferritin alterations in human breast cancer cells

scientific article published in February 2011

Status of hepatic DNA methylome predetermines and modulates the severity of non-alcoholic fatty liver injury in mice

scientific article

Strain-dependent dysregulation of one-carbon metabolism in male mice is associated with choline- and folate-deficient diet-induced liver injury

scientific article published on 25 February 2013

Suppressing activity of tributyrin on hepatocarcinogenesis is associated with inhibiting the p53-CRM1 interaction and changing the cellular compartmentalization of p53 protein.

scientific article published on 22 March 2016

The chemopreventive activity of the butyric acid prodrug tributyrin in experimental rat hepatocarcinogenesis is associated with p53 acetylation and activation of the p53 apoptotic signaling pathway

scientific article published on 08 April 2013

The role of epigenetic events in genotoxic hepatocarcinogenesis induced by 2-acetylaminofluorene

scientific article published on 25 February 2010

The tumor-promoting activity of 2-acetylaminofluorene is associated with disruption of the p53 signaling pathway and the balance between apoptosis and cell proliferation

scientific article published on 6 January 2009

Transcriptomic responses provide a new mechanistic basis for the chemopreventive effects of folic acid and tributyrin in rat liver carcinogenesis

scientific article

List of works by Igor P Pogribny

An in vitro investigation of metabolically sensitive biomarkers in breast cancer progression

Cerebellar oxidative DNA damage and altered DNA methylation in the BTBR T+tf/J mouse model of autism and similarities with human post mortem cerebellum

Chronic administration of 2-acetylaminofluorene alters the cellular iron metabolism in rat liver

Coupling global methylation and gene expression profiles reveal key pathophysiological events in liver injury induced by a methyl-deficient diet

Dietary methyl deficiency, microRNA expression and susceptibility to liver carcinogenesis

Dietary methyl deficiency, microRNA expression and susceptibility to liver carcinogenesis

Difference in expression of hepatic microRNAs miR-29c, miR-34a, miR-155, and miR-200b is associated with strain-specific susceptibility to dietary nonalcoholic steatohepatitis in mice

Differential expression of microRNAs during hepatocarcinogenesis induced by methyl deficiency in rats

Differentially expressed MicroRNAs provide mechanistic insight into fibrosis-associated liver carcinogenesis in mice

Down-regulation of the microRNAs miR-34a, miR-127, and miR-200b in rat liver during hepatocarcinogenesis induced by a methyl-deficient diet

E-cadherin transcriptional down-regulation by epigenetic and microRNA-200 family alterations is related to mesenchymal and drug-resistant phenotypes in human breast cancer cells

Effect of an obesogenic high-fat and high-sucrose diet on hepatic gene expression signatures in male Collaborative Cross mice

Effect of long-term tamoxifen exposure on genotoxic and epigenetic changes in rat liver: implications for tamoxifen-induced hepatocarcinogenesis

Effect of methionine-deficient and methionine-supplemented diets on the hepatic one-carbon and lipid metabolism in mice

Epigenetic alterations in liver of C57BL/6J mice after short-term inhalational exposure to 1,3-butadiene

Epigenetic effects of low-level sodium arsenite exposure on human liver HepaRG cells

Epigenetic reprogramming of liver cells in tamoxifen-induced rat hepatocarcinogenesis

Furan-induced transcriptomic and gene-specific DNA methylation changes in the livers of Fischer 344 rats in a 2-year carcinogenicity study

Gene expression and cytosine DNA methylation alterations in induced pluripotent stem-cell-derived human hepatocytes treated with low doses of chemical carcinogens

Gene expression profiling reveals underlying molecular mechanisms of the early stages of tamoxifen-induced rat hepatocarcinogenesis

Genetic and epigenetic changes in fibrosis-associated hepatocarcinogenesis in mice

Genotoxic and Epigenotoxic Alterations in the Lung and Liver of Mice Induced by Acrylamide: A 28 Day Drinking Water Study

Genotoxic, epigenetic, and transcriptomic effects of tamoxifen in mouse liver

Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet

Identification of chromatin-accessible domains in non-alcoholic steatohepatitis-derived hepatocellular carcinoma

Induction of microRNAome deregulation in rat liver by long-term tamoxifen exposure

Interstrain differences in the progression of nonalcoholic steatohepatitis to fibrosis in mice are associated with altered hepatic iron metabolism

Interstrain differences in the severity of liver injury induced by a choline- and folate-deficient diet in mice are associated with dysregulation of genes involved in lipid metabolism

Iron metabolism disturbances in the MCF-7 human breast cancer cells with acquired resistance to doxorubicin and cisplatin

Irreversible down-regulation of miR-375 in the livers of Fischer 344 rats after chronic furan exposure

Mechanisms of epigenetic silencing of the Rassf1a gene during estrogen-induced breast carcinogenesis in ACI rats

MicroRNA Responses to the Genotoxic Carcinogens Aflatoxin B1 and Benzo[a]pyrene in Human HepaRG Cells

MicroRNA changes, activation of progenitor cells and severity of liver injury in mice induced by choline and folate deficiency

MicroRNA-152-mediated dysregulation of hepatic transferrin receptor 1 in liver carcinogenesis

Modifying metabolically sensitive histone marks by inhibiting glutamine metabolism affects gene expression and alters cancer cell phenotype

Modulation of intracellular iron metabolism by iron chelation affects chromatin remodeling proteins and corresponding epigenetic modifications in breast cancer cells and increases their sensitivity to chemotherapeutic agents

Persistence of furan-induced epigenetic aberrations in the livers of F344 rats.

Plasma microRNAs are sensitive indicators of inter-strain differences in the severity of liver injury induced in mice by a choline- and folate-deficient diet

Population-Based Analysis of DNA Damage and Epigenetic Effects of 1,3-Butadiene in the Mouse

Role of ferritin alterations in human breast cancer cells

Status of hepatic DNA methylome predetermines and modulates the severity of non-alcoholic fatty liver injury in mice

Strain-dependent dysregulation of one-carbon metabolism in male mice is associated with choline- and folate-deficient diet-induced liver injury

Suppressing activity of tributyrin on hepatocarcinogenesis is associated with inhibiting the p53-CRM1 interaction and changing the cellular compartmentalization of p53 protein.

The chemopreventive activity of the butyric acid prodrug tributyrin in experimental rat hepatocarcinogenesis is associated with p53 acetylation and activation of the p53 apoptotic signaling pathway

The role of epigenetic events in genotoxic hepatocarcinogenesis induced by 2-acetylaminofluorene

The tumor-promoting activity of 2-acetylaminofluorene is associated with disruption of the p53 signaling pathway and the balance between apoptosis and cell proliferation

Transcriptomic responses provide a new mechanistic basis for the chemopreventive effects of folic acid and tributyrin in rat liver carcinogenesis