List of works - Apirat Chaikuad

A Chemical Probe for Dark Kinase STK17B Derives Its Potency and High Selectivity through a Unique P-Loop Conformation

scientific article published on 20 November 2020

A structure-based approach towards identification of inhibitory fragments for eleven-nineteen-leukemia protein (ENL)

scientific article published on 26 November 2018

Chemical Starting Matter for HNF4α Ligand Discovery and Chemogenomics

scientific article published on 24 October 2020

Comprehensive Set of Tertiary Complex Structures and Palmitic Acid Binding Provide Molecular Insights into Ligand Design for RXR Isoforms

scientific article published on 11 November 2020

Conservation of structure, function and inhibitor binding in UNC-51-like kinase 1 and 2 (ULK1/2)

scientific article published on 12 March 2019

Copper is required for oncogenic BRAF signalling and tumorigenesis

scientific article (publication date: 22 May 2014)

Crystal Structure and Inhibitor Identifications Reveal Targeting Opportunity for the Atypical MAPK Kinase ERK3

scientific article published on 26 October 2020

Design, Synthesis, and Characterization of an Orally Active Dual-Specific ULK1/2 Autophagy Inhibitor that Synergizes with the PARP Inhibitor Olaparib for the Treatment of Triple-Negative Breast Cancer

scientific article published on 17 November 2020

Development, Optimization, and Structure-Activity Relationships of Covalent-Reversible JAK3 Inhibitors Based on a Tricyclic Imidazo[5,4- d]pyrrolo[2,3- b]pyridine Scaffold

scientific article published on 13 June 2018

Discovery of a Novel Class of Covalent Dual Inhibitors Targeting the Protein Kinases BMX and BTK

scientific article published on 04 December 2020

Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain

scientific article published on 17 September 2019

Fast Iterative Synthetic Approach toward Identification of Novel Highly Selective p38 MAP Kinase Inhibitors

scientific article published on 26 November 2019

Halogen-Aromatic π Interactions Modulate Inhibitor Residence Times.

scientific article

Hepatitis Delta Virus histone mimicry drives the recruitment of chromatin remodelers for viral RNA replication

scientific article published on 21 January 2020

How to Separate Kinase Inhibition from Undesired Monoamine Oxidase A Inhibition-The Development of the DYRK1A Inhibitor AnnH75 from the Alkaloid Harmine

scientific article published on 16 December 2020

Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action.

scientific article published on 18 October 2017

[b]-Annulated Halogen-Substituted Indoles as Potential DYRK1A Inhibitors

scientific article published on 13 November 2019

p63 uses a switch-like mechanism to set the threshold for induction of apoptosis

scientific article published on 27 July 2020

List of works by Apirat Chaikuad