Search filters

List of works by Luke W Koblan

A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity.

scientific article

Addendum: High-resolution specificity profiling and off-target prediction for site-specific DNA recombinases

scientific article published on 02 July 2019

Adenine base editing in an adult mouse model of tyrosinaemia

scientific article published on 25 February 2019

Assessment of Bromodomain Target Engagement by a Series of BI2536 Analogues with Miniaturized BET-BRET.

scientific article

Author Correction: Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity

scientific article published on 20 May 2020

Base editing of haematopoietic stem cells rescues sickle cell disease in mice

scientific article published on 02 June 2021

Continuous evolution of base editors with expanded target compatibility and improved activity

scientific article published on 22 July 2019

Cytosine and adenine base editing of the brain, liver, retina, heart and skeletal muscle of mice via adeno-associated viruses

scientific article published on 14 January 2020

Genome editing with CRISPR-Cas nucleases, base editors, transposases and prime editors

scientific article published on 22 June 2020

High-resolution specificity profiling and off-target prediction for site-specific DNA recombinases

scientific article published on 26 April 2019

Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity.

scientific article published on 30 August 2017

Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction

scientific article published on 29 May 2018

In vivo base editing rescues Hutchinson-Gilford progeria syndrome in mice

scientific article published on 06 January 2021

Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity

scientific article published on 16 March 2020

Publisher Correction: Continuous evolution of base editors with expanded target compatibility and improved activity

scientific article published on 01 September 2019