Search filters

List of works by Victor R Gordeuk

"Maximum tolerated dose" vs "fixed low-dose" hydroxyurea for treatment of adults with sickle cell anemia

scientific article published on 06 February 2019

A Case Series: Chiari Malformation and Sickle Cell Disease ⬇️

scholarly article

A Comparison Of Sickle Cell Anemia Between Patients From Nigeria and The United States ⬇️

scholarly article

A Multi-Center, Phase-2 Trial of Losartan for the Nephropathy of Sickle Cell Anemia ⬇️

scholarly article

A Novel EGLN1/PHD2 High-Frequency Variant in Tibetans Protects Against Hypoxia-Induced Polycythemia. ⬇️

scholarly article

A Phase 3 Randomized Trial of Voxelotor in Sickle Cell Disease

scientific article published on 14 June 2019

A Phase 3 Trial of l-Glutamine in Sickle Cell Disease

scientific article published on 01 July 2018

A Plasmodium-encoded cytokine suppresses T-cell immunity during malaria

scientific article

A critical role for the host mediator macrophage migration inhibitory factor in the pathogenesis of malarial anemia

scientific article

A critical role for the host mediator macrophage migration inhibitory factor in the pathogenesis of malarial anemia

scientific article published on 01 May 2015

A genetic mechanism for Tibetan high-altitude adaptation

scientific article

A genetic variation associated with plasma erythropoietin and a non-coding transcript of PRKAR1A in sickle cell disease

scientific article published in October 2016

A novel molecular signature for elevated tricuspid regurgitation velocity in sickle cell disease

scientific article

APOL1, α-thalassemia, and BCL11A variants as a genetic risk profile for progression of chronic kidney disease in sickle cell anemia

scientific article published on 22 September 2016

ARTS: automated randomization of multiple traits for study design

scientific article published on 3 February 2014

Abnormal pulmonary function and associated risk factors in children and adolescents with sickle cell anemia

scientific article

Age As an Independent Clinical Predictor for Vitamin D Deficiency in Sickle Cell Disease ⬇️

scholarly article

Altered Blood Gene Transcription in Chuvash Polycythemia and Its Cell Lineage Specificity ⬇️

scholarly article

Altered cytokine profiles in patients with Chuvash polycythemia

scientific article

An official American Thoracic Society clinical practice guideline: diagnosis, risk stratification, and management of pulmonary hypertension of sickle cell disease

scientific article published on March 2014

Angiogenic and inflammatory markers of cardiopulmonary changes in children and adolescents with sickle cell disease

scientific article

Antimicrobial resistance is a risk factor for mortality in adults with sickle cell disease

scientific article published on 29 October 2020

Assessment of Bone Marrow Function in Sickle Cell Anaemia Patients Using Corrected Reticulocyte Counts ⬇️

scholarly article

Association of FOXO3A Polymorphisms with Hematocrit, LDH and Longevity in Patients with Sickle Cell Anemia from CSSCD, Walk-Phasst, and PUSH Clinical Trials ⬇️

scholarly article

Association of G6PD with lower haemoglobin concentration but not increased haemolysis in patients with sickle cell anaemia

scientific article

Association of Helicobacter Pylori Infection with Iron Deficiency in Asians and Pacific Islanders but not in Caucasians, African Americans, or Hispanics ⬇️

scholarly article

Association of circulating transcriptomic profiles with mortality in sickle cell disease

scientific article

Association of serum transferrin receptor concentration with markers of inflammation in Zimbabwean children

scientific article published on 17 April 2006

Associations of α-thalassemia and BCL11A with stroke in Nigerian, United States, and United Kingdom sickle cell anemia cohorts

scientific article published on 01 April 2017

Biomarker signatures of sickle cell disease severity

scientific article published on 16 May 2018

Blood transfusion and 30-day readmission rate in adult patients hospitalized with sickle cell disease crisis

scientific article

Brief Report: Hydroxychloroquine does not induce hemolytic anemia or organ damage in a "humanized" G6PD A- mouse model

scientific article published on 02 October 2020

COVID-19 Infection in Patients with Sickle Cell Disease

scientific article published on 21 April 2020

CYB5R3c .350C>G and G6PD A Alleles Modify Severity of Anemia in Malaria and Sickle Cell Disease

scientific article published on 22 July 2020

Cancer Incidence in Sickle Cell Disease:an Institutional Experience ⬇️

scholarly article

Cardiopulmonary Functional Status in Children with SCD at Baseline: Pulse Pressure As a Biomarker of Early Compromise ⬇️

scholarly article

Cell-Free Hemoglobin, HMOX1 and APOL1 in Sickle Cell Nephropathy ⬇️

scholarly article

Changes in Conjunctival Hemodynamics Predict Albuminuria in Sickle Cell Nephropathy

scientific article

Characterization of opioid use in sickle cell disease

scientific article published on 16 August 2017

Chronic Opioid Use Pattern in Adult Patients with Sickle Cell Disease ⬇️

scholarly article

Chronic Pain Is An Independent Predictor of Lower 6 Minute Walk Distance In Patients with Sickle Cell Disease: Results From Walk-PHaSST Study ⬇️

scholarly article

Chronic opioid use can be reduced or discontinued after haematopoietic stem cell transplantation for sickle cell disease

scientific article published on 21 July 2020

Chuvash polycythemia VHLR200W mutation is associated with down-regulation of hepcidin expression

scientific article published on 29 August 2011

Cigarette Smoking Is An Independent Predictor of Chronic Pain In Sickle Cell Patients: Results From the Walk-PHaSST Study ⬇️

scholarly article

Circumstances of death in adult sickle cell disease patients

scientific article published in November 2006

Clinical Efficacy and Safety of Erythroid Stimulating Agents in Sickle Cell Disease ⬇️

scholarly article

Clinical and Genetic Variability of Red Blood Cell Hemolysis in Sickle Cell Anemia ⬇️

scholarly article

Clinical and Laboratory Predictors for Renal Damage in Sickle Cell Disease ⬇️

scholarly article

Clinical correlates of acute pulmonary events in children and adolescents with sickle cell disease

scientific article published on 03 May 2013

Clinical, laboratory, and genetic risk factors for thrombosis in sickle cell disease

scientific article published on 01 May 2020

Comparing the Effectiveness of Education Versus Digital Cognitive Behavioral Therapy for Adults With Sickle Cell Disease: Protocol for the Cognitive Behavioral Therapy and Real-time Pain Management Intervention for Sickle Cell via Mobile Application

scientific article published on 29 March 2021

Comparison of patients from Nigeria and the USA highlights modifiable risk factors for sickle cell anemia complications

scientific article

Complete blood count, measures of iron status and inflammatory markers in inner-city African Americans with undiagnosed hepatitis C seropositivity

scientific article

Complications in children and adolescents with Chuvash polycythemia

scientific article published in January 2015

Congenital disorder of oxygen sensing: association of the homozygous Chuvash polycythemia VHL mutation with thrombosis and vascular abnormalities but not tumors

scientific article published on 15 January 2004

Congenital polycythemias/erythrocytoses.

scientific article

Conjunctival and pulmonary hemodynamic properties in sickle cell disease subjects with and without pulmonary hypertension.

scientific article published on 6 November 2015

Correlation of Voxelotor Exposure with Hemoglobin Response and Measures of Hemolysis in Patients from the HOPE Study ⬇️

scholarly article

Could hypoxia increase the prevalence of thrombotic complications in polycythemia vera? ⬇️

scientific article published on April 1, 2013

Could the Increased Prevalence of Thrombotic Complications at High Altitude In Polycythemia Vera (PV) Be Contributed by Hypoxia? ⬇️

scholarly article

Crizanlizumab for the Prevention of Pain Crises in Sickle Cell Disease

scientific article

Cytochrome B5 Reductase T116S Polymorphism Is Associated with Decreased Risk of Severe Anemia Among Zambian Children with Malaria ⬇️

scholarly article

Cytochrome b5 Reductase T116S Mutation and Hemolysis in Sickle Cell Disease. ⬇️

scholarly article

Decreased serum glucose and glycosylated hemoglobin levels in patients with Chuvash polycythemia: a role for HIF in glucose metabolism

scientific article published on 27 September 2012

Design of the patient navigator to Reduce Readmissions (PArTNER) study: A pragmatic clinical effectiveness trial

scientific article published on 19 July 2019

Development of a Severity Classification System for Sickle Cell Disease

scientific article published on 28 October 2020

Development of a sensitive HPLC method to measure in vitro permeability of E- and Z-isomeric forms of thiosemicarbazones in Caco-2 monolayers ⬇️

scientific article published on August 15, 2012

Dietary iron intake and serum ferritin concentration in 213 patients homozygous for the HFEC282Y hemochromatosis mutation

scientific article

Differences in the clinical and genotypic presentation of sickle cell disease around the world

scientific article

Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia

scientific article

Distinct clinical and immunologic profiles in severe malarial anemia and cerebral malaria in Zambia

scientific article

Early Detection of Renal Dysfunction in Pediatric Sickle Cell Patients ⬇️

scholarly article

Echocardiographic findings in patients with sickle cell disease

scientific article published on 02 June 2009

Echocardiographic markers of elevated pulmonary pressure and left ventricular diastolic dysfunction are associated with exercise intolerance in adults and adolescents with homozygous sickle cell anemia in the United States and United Kingdom

scientific article

Effect of Angiotensin Converting Enzyme Inhibitors and Angiotensin Receptor Blockers on Kidney Function in Patients with Sickle Cell Disease ⬇️

scholarly article

Effect of Phlebotomy Therapy On Hemoglobin Concentration and Tricuspid Regurgitation Velocity in Chuvash Polycythemia. ⬇️

scholarly article

Effect of congenital upregulation of hypoxia inducible factors on percentage of fetal hemoglobin in the blood

scientific article published on October 2013

Effect of ferroportin Q248H polymorphism on iron status in African children

scientific article

Efficacy and Safety of 1500 mg Voxelotor in a Phase 2a Study (GBT440-007) in Adolescents with Sickle Cell Disease ⬇️

scholarly article

Elevated Estimated Pulmonary Arterial Pressures in Patients with Chuvash Polycythemia. ⬇️

scholarly article

Elevated Levels of Hgfl Protein in Sickle Cell Disease Urine Samples That Induce Glomerular Permeability ⬇️

scholarly article

Elevated homocysteine, glutathione and cysteinylglycine concentrations in patients homozygous for the Chuvash polycythemia VHL mutation

scientific article

Elevated tricuspid regurgitant jet velocity in children and adolescents with sickle cell disease: association with hemolysis and hemoglobin oxygen desaturation

scientific article published on 11 February 2009

Elevated tricuspid regurgitation velocity and decline in exercise capacity over 22 months of follow up in children and adolescents with sickle cell anemia

scientific article

Endemic polycythemia in Russia: mutation in the VHL gene

scientific article published in January 2002

Endothelin-1, vascular endothelial growth factor and systolic pulmonary artery pressure in patients with Chuvash polycythemia

scientific article published on 01 June 2006

Engulfment and cell motility 1 (ELMO1) and apolipoprotein A1 (APOA1) as candidate genes for sickle cell nephropathy

scientific article published on 20 November 2020

Erythrocytic ferroportin reduces intracellular iron accumulation, hemolysis, and malaria risk.

scientific article published in March 2018

Erythropoiesis-stimulating agents in sickle cell anaemia.

scientific article published on 27 July 2017

Evaluation of Exercise Capacity In Children with SCD by Six Minute Walk Test ⬇️

scholarly article

Feasibility of implementing a comprehensive warfarin pharmacogenetics service

scientific article published on 17 July 2013

Ferroportin (SLC40A1) Q248H mutation is associated with lower circulating plasma tumor necrosis factor-alpha and macrophage migration inhibitory factor concentrations in African children.

scientific article

Ferroportin Q248h, dietary iron, and serum ferritin in community African-Americans with low to high alcohol consumption.

scientific article

Fixed Low-Dose Hydroxyurea for the Treatment of Adults with Sickle Cell Anemia in Nigeria

scientific article published on 14 May 2018

Fluorescence measurements of the labile iron pool of sickle erythrocytes

scientific article published on 6 March 2003

GWAS Meta-Analysis of Glomerular Filtration Rate in Three Cohorts of Sickle Cell Disease Patients and In Vivo Functional Analysis Reveals Potential Nephropathy Candidate Genes ⬇️

scholarly article

Gain-of-function EGLN1 prolyl hydroxylase (PHD2 D4E:C127S) in combination with EPAS1 (HIF-2α) polymorphism lowers hemoglobin concentration in Tibetan highlanders

scientific article published on 23 February 2017

Gene Expression Profiling In Peripheral Blood Mononuclear Cells Correlates Chuvash Polycythemia Progression To Pulmonary Hypertension

article

Genetic Association Of a MAPK8 Expression Quantitative Trait Locus With Pre-Capillary Pulmonary Hypertension In Sickle Cell Disease ⬇️

scholarly article

Genetic Modifiers Identify a High Risk Group for Stroke in Three Independent Cohorts of Sickle Cell Anemia Patients ⬇️

scholarly article

Genetic determinants of haemolysis in sickle cell anaemia

scientific article

Genetic polymorphism of APOB is associated with diabetes mellitus in sickle cell disease

scientific article

Genetic variants and cell-free hemoglobin processing in sickle cell nephropathy

scientific article

Genome-Wide Analysis Identifies IL-18 and FUCA2 as Novel Genes Associated with Diastolic Function in African Americans with Sickle Cell Disease

scientific article

Genomic Assessment of Mortality in Sickle Cell Disease- A Novel Association with Cytokine Imbalance and T Cell Dysregulation ⬇️

scholarly article

Geographic and Racial/Ethnic Differences in HFE Mutation Frequencies and Iron Phenotypes in the Hemochromatosis and Iron Overload Screening (HEIRS) Study. ⬇️

scholarly article

HMOX1 and acute kidney injury in sickle cell anemia

scientific article published on 23 August 2018

Haemoglobinuria is associated with chronic kidney disease and its progression in patients with sickle cell anaemia

scientific article published on 12 December 2013

Haploidentical Peripheral Blood Stem Cell Transplantation Demonstrates Stable Engraftment in Adults with Sickle Cell Disease

scientific article published on 12 April 2018

Haptoglobin 1 Allele Predicts Higher Serum Haptoglobin and Lower Multiorgan Failure Risk in Sickle Cell Disease

scientific article published in 2022

Health Care Utilization in Transplanted Versus Non-Transplanted Sickle Cell Disease Patients ⬇️

scholarly article

Hemoglobinuria Is a Risk Factor For Kidney Disease Progression In Sickle Cell Anemia ⬇️

scholarly article

Hemolysis and hemolysis-related complications in females vs. males with sickle cell disease

scientific article published on 17 October 2018

Hepatic macrophage iron aggravates experimental alcoholic steatohepatitis

scientific article published on 3 July 2008

High Inpatient Dose of Opioid at Discharge Compared to Home Dose Predicts Readmission Risk in Sickle Cell Disease

article

Hospitalization for pain in patients with sickle cell disease treated with sildenafil for elevated TRV and low exercise capacity

scientific article

Host Genetic Factors in Glucose-6-Phosphate Dehydrogenase and Cytochrome B5 Reductase 3 Affect the Susceptibility of Developing Severe Malarial Anemia ⬇️

scholarly article

Hydroxycarbamide adherence and cumulative dose associated with hospital readmission in sickle cell disease: a 6-year population-based cohort study.

scientific article

Hydroxyurea for Treatment of Sickle Cell Disease in Adults in Africa ⬇️

scholarly article

Hyperfiltration Is a Risk Factor For The Development Of Microalbuminuria In Sickle Cell Anemia ⬇️

scholarly article

Hyperfiltration is associated with the development of microalbuminuria in patients with sickle cell anemia

scientific article

Hypoxia Inducible Factors' Transcriptional Activity in Polycythemia Vera ⬇️

scholarly article

Hypoxic response contributes to altered gene expression and precapillary pulmonary hypertension in patients with sickle cell disease

scientific article

Identification of ceruloplasmin as a biomarker of chronic kidney disease in urine of sickle cell disease patients by proteomic analysis

scientific article published on 10 November 2017

Identifying Clinical and Research Priorities in Sickle Cell Lung Disease. An Official American Thoracic Society Workshop Report

scientific article published on 01 September 2019

Identifying adolescent and young adult patients with sickle cell disease at highest risk of death

scientific article published on 27 October 2020

Impact of Intravenous Opioid Shortage on Managing Pain Crisis in Sickle Cell Disease ⬇️

scholarly article

Impact of a Clinical Pharmacy Service on the Management of Patients in a Sickle Cell Disease Outpatient Center

scientific article

Impact of a Dedicated Sickle Cell Acute Care Observation Unit on Rate of Hospital Admission for Acute Pain Crisis ⬇️

scholarly article

Implementation of a Standard Order Set at a Sickle Cell Acute Care Observation Unit ⬇️

scholarly article

Improved health care utilization and costs in transplanted versus non-transplanted adults with sickle cell disease

scientific article published on 26 February 2020

Increased iron stores influence glucose metabolism in sickle cell anaemia

scientific article published on 30 March 2020

Increased size of solid organs in patients with Chuvash polycythemia and in mice with altered expression of HIF-1alpha and HIF-2alpha

scientific article

Increased vancomycin dosing requirements in sickle cell disease due to hyperfiltration-dependent and independent pathways

scientific article published on 4 May 2017

Inflammation, Multiple Blood Transfusions and Osteoclast Activation in Sickle Cell Disease Patients. ⬇️

scholarly article

Influence of single parenthood on cardiopulmonary function in pediatric patients with sickle cell anemia

scientific article published on 01 July 2020

Inhibition of HIV-1 by DpT-Based Iron Chelators ⬇️

scholarly article

Inhibition of HIV-1 in Sickle Cell Disease Peripheral Blood Mononuclear Cells. ⬇️

scholarly article

Initial screening transferrin saturation values, serum ferritin concentrations, and HFE genotypes in whites and blacks in the Hemochromatosis and Iron Overload Screening Study

scientific article published in January 2005

Integration of Genomic and Genetic Approaches Highlight a Novel Validated Gene Signature for Pulmonary Hypertension Associated with Sickle Cell Disease ⬇️

scholarly article

Integration of Mobile Health Into Sickle Cell Disease Care to Increase Hydroxyurea Utilization: Efficacy and Implementation Study

scientific article published on 07 April 2020

Iron Chelation, Cell Cycle-Dependent Kinases and HIV-1 Transcription. ⬇️

scholarly article

Iron chelators ICL670 and 311 inhibit HIV-1 transcription

scientific article

Iron deficiency modifies gene expression variation induced by augmented hypoxia sensing

scientific article published on 28 August 2013

Iron, inflammation, and early death in adults with sickle cell disease

scientific article

Kidney Disease among Patients with Sickle Cell Disease, Hemoglobin SS and SC.

scientific article published on 15 December 2015

Kidney ultrasound findings according to kidney function in sickle cell anemia

scientific article published on 18 August 2019

Laboratory and echocardiography markers in sickle cell patients with leg ulcers ⬇️

scientific article published on 31 May 2011

Lack of Association between Single Nucleotide Polymorphism rs3811647 in the TF Gene and Iron Status in Patients with Iron Deficiency and Control Subjects ⬇️

scholarly article

Laparoscopic Sleeve Gastrectomy in Sickle Cell Disease: a Case Series

scientific article published on 01 November 2019

Losartan for the nephropathy of sickle cell anemia: A phase-2, multicenter trial.

scientific article published on 7 June 2017

Low Hemoglobin Increases Risk for Stroke, Kidney Disease, Elevated Estimated Pulmonary Artery Systolic Pressure, and Premature Death in Sickle Cell Disease: A Systematic Literature Review and Meta-Analysis ⬇️

scholarly article

Manifestations of Reduced Kidney Function Occur at a Higher Estimated Glomerular Filtration Rate in Sickle Cell Anemia ⬇️

scholarly article

Markers of severe vaso-occlusive painful episode frequency in children and adolescents with sickle cell anemia

scientific article published on 3 September 2011

Maximum Tolerated Dose Versus Fixed Low-Dose Hydroxyurea for Treatment of Adults with Sickle Cell Anemia - Retrospective Comparison of Two Studies ⬇️

scholarly article

Meta-analysis of 2040 sickle cell anemia patients: BCL11A and HBS1L-MYB are the major modifiers of HbF in African Americans

scientific article published on August 2012

Metabolic aspects of high-altitude adaptation in Tibetans.

scientific article published on 06 June 2015

Multivariate Genomic Analyses Predict The Presence Of Pulmonary Hypertension In Chuvash Polycythemia

NT-Probnp as a Marker of Cardiopulmonary Compromise and Exercise Limitation In Adults with Sickle Cell Anemia In the Walk-PHaSST Study ⬇️

scholarly article

NT-proBNP as a marker of cardiopulmonary status in sickle cell anaemia in Africa

scientific article

Neurdevelopmental Deficits Among 80 Infants and Toddlers with Sickle Cell Disease ⬇️

scholarly article

Neurodevelopmental deficits among infants and toddlers with sickle cell disease.

scientific article published in July 2013

Nitric oxide for inhalation in the acute treatment of sickle cell pain crisis: a randomized controlled trial

scientific article

Non-Competitive Protein Phosphatase-1 Inhibitors Prevent Sickling of SS RBCs. ⬇️

scholarly article

Nonmyeloablative Stem Cell Transplantation with Alemtuzumab/Low-Dose Irradiation to Cure and Improve the Quality of Life of Adults with Sickle Cell Disease

scientific article published on 5 September 2015

Novel Putative Polymorphism in SERPINC1 Encoding Antithrombin III Is Implicated in Elevated Estimated Systolic Pulmonary Pressure in Patients with Chuvash Polycythemia. ⬇️

scholarly article

Oral tetrahydrouridine and decitabine for non-cytotoxic epigenetic gene regulation in sickle cell disease: A randomized phase 1 study.

scientific article published on 7 September 2017

Outcome Disparities in Caucasian and Non-Caucasian Patients With Myeloproliferative Neoplasms

scientific article published on 8 March 2016

Pain Medication: Time to First Dose in Sickle Cell Acute Care in Two Settings of a Large Urban Hospital ⬇️

scholarly article

Pathophysiology and treatment of pulmonary hypertension in sickle cell disease

scientific article published on 12 January 2016

Patient-reported Outcomes in Sickle Cell Disease and Association with Clinical and Psychosocial Factors: Report from the Sickle Cell Disease Implementation Consortium

scientific article published on 25 May 2020

Patrolling the endothelium in sickle cell disease

scientific article published on 01 April 2018

Patterns of opioid use in sickle cell disease

scientific article published on 28 July 2016

Peripheral blood mononuclear cells show prominent gene expression by erythroid progenitors in diseases characterized by heightened erythropoiesis

scientific article published on 12 May 2020

Plasma thrombospondin-1 is increased during acute sickle cell vaso-occlusive events and associated with acute chest syndrome, hydroxyurea therapy, and lower hemolytic rates

scientific article published on 8 February 2012

Platelets decline during Vaso-occlusive crisis as a predictor of acute chest syndrome in sickle cell disease

scientific article published on 9 October 2015

Potential Contribution of Pulmonary Thromboembolic Disease in Pulmonary Hypertension in Sickle Cell Disease

scientific article published on 18 March 2020

Prediction of fetal hemoglobin in sickle cell anemia using an ensemble of genetic risk prediction models

scientific article published on March 2014

Predictors of Maternal Morbidity Among Participants Enrolled in the Sickle Cell Disease Implementation Consortium Registry

Predictors of Mortality in Children and Adolescents with Sickle Cell Disease: The PUSH Study ⬇️

scholarly article

Predictors of osteoclast activity in patients with sickle cell disease

scientific article

Prevalence and risk factors for pulmonary artery systolic hypertension among sickle cell disease patients in Nigeria

scientific article

Prevalence of Pulmonary Hypertension (PHTN) in Sickle Cell Disease (SCD) Adolescents with Pulmonary Complications. ⬇️

scholarly article

Prevalence of Sickle Cell Trait and Rare Hemoglobin Variants in the Metropolitan Washington DC Area

scientific article published on 14 August 2020

Preventing delayed hemolytic transfusion reactions in sickle cell disease

scientific article published in November 2016

Program expansion of a day hospital dedicated to manage sickle cell pain.

scientific article published on 11 October 2017

Progressive glomerular and tubular damage in sickle cell trait and sickle cell anemia mouse models

scientific article published on 2 February 2018

Prospective echocardiography assessment of pulmonary hypertension and its potential etiologies in children with sickle cell disease

scientific article

Prospective evaluation of haemoglobin oxygen saturation at rest and after exercise in paediatric sickle cell disease patients

scientific article published on 19 August 2009

Prospective study of thrombosis and thrombospondin-1 expression in Chuvash polycythemia

scientific article published on 19 January 2017

Protective effect of HLA-DQB1 alleles against alloimmunization in patients with sickle cell disease

scientific article published on 14 October 2015

Protein Phosphatase-1 Activates CDK9 by Dephosphorylating Ser175 ⬇️

scientific article published on April 21, 2011

Publication of data collection forms from NHLBI funded sickle cell disease implementation consortium (SCDIC) registry

scientific article published on 07 July 2020

Pulmonary artery pressure and iron deficiency in patients with upregulation of hypoxia sensing due to homozygous VHL(R200W) mutation (Chuvash polycythemia).

scientific article published on 11 October 2011

Pulmonary hypertension and NO in sickle cell

scientific article published on August 2010

Randomized phase 2 trial of regadenoson for treatment of acute vaso-occlusive crises in sickle cell disease

scientific article published on 28 August 2017

Re-evaluation of hematocrit as a determinant of thrombotic risk in erythrocytosis

scholarly article by Victor R Gordeuk et al published April 2019 in Haematologica

Red blood cell alloimmunization in sickle cell disease: assessment of transfusion protocols during two time periods.

scientific article published on 23 March 2018

Reduced Sensitivity of the Ferroportin Q248H Mutant to Low Concentrations of Hepcidin. ⬇️

scholarly article

Reduced sensitivity of the ferroportin Q248H mutant to physiological concentrations of hepcidin

scientific article published on 12 October 2012

Reference intervals of serum transferrin receptors in pre-school children in Zimbabwe

scientific article published on 11 April 2007

Regulatory Genetic Variation at the S100B Gene Associates with Vaso-Occlusive Manifestations in Sickle Cell Disease ⬇️

scholarly article

Relationship of erythropoietin, fetal hemoglobin, and hydroxyurea treatment to tricuspid regurgitation velocity in children with sickle cell disease

scientific article published on September 2009

Relative systemic hypertension in patients with sickle cell disease is associated with risk of pulmonary hypertension and renal insufficiency

scientific article

Reply to Ruan X et al: "A comment on pattern of opioid use in sickle cell disease".

scientific article

Reply: Practice guideline for pulmonary hypertension in sickle cell: direct evidence needed before universal adoption

scientific article published in July 2014

Results from Part A of the Hemoglobin Oxygen Affinity Modulation to Inhibit HbS Polymerization (HOPE) Trial (GBT440-031), a Placebo-Controlled Randomized Study Evaluating Voxelotor (GBT440) in Adults and Adolescents with Sickle Cell Disease ⬇️

scholarly article

Risk Factors for Death in 632 Patients with Sickle Cell Anemia in the United States and United Kingdom ⬇️

scholarly article

Risk factors for death in 632 patients with sickle cell disease in the United States and United Kingdom

scientific article

Risk factors for vitamin D deficiency in sickle cell disease.

scientific article published on 16 May 2018

Role of Ethnicity in Clinical Outcomes of Patients with Ph-Negative Myeloproliferative Neoplasms ⬇️

scholarly article

S100B has pleiotropic effects on vaso-occlusive manifestations in sickle cell disease

scientific article published on 01 January 2020

SUSTAIN: A Multicenter, Randomized, Placebo-Controlled, Double-Blind, 12-Month Study to Assess Safety and Efficacy of SelG1 with or without Hydroxyurea Therapy in Sickle Cell Disease Patients with Sickle Cell-Related Pain Crises ⬇️

scholarly article

Safety and Efficacy of Sildenafil Therapy for Doppler-Defined Pulmonary Hypertension in Patients with Sickle Cell Disease: Preliminary Results of the Walk-PHaSST Clinical Trial. ⬇️

scholarly article

Safety of chronic transdermal fentanyl use in patients receiving hemodialysis

scientific article published on July 2016

Senicapoc trial results support the existence of different sub-phenotypes of sickle cell disease with possible drug-induced phenotypic shifts

scientific article published on 07 July 2011

Serum albumin is independently associated with higher mortality in adult sickle cell patients: Results of three independent cohorts

scientific article published on 10 August 2020

Severe Vaso-Occlusive Episodes Associated with Use of Systemic Corticosteroids in Patients with Sickle Cell Disease

scientific article published in August 2008

Severe vaso-occlusive episodes associated with use of systemic corticosteroids in patients with sickle cell disease

scientific article published on August 2008

Sickle Cell Disease Clinical Trials and Phenotypes

Sickle cell disease and pulmonary hypertension in Africa: a global perspective and review of epidemiology, pathophysiology, and management

scientific article published on January 2008

Sickle cell disease is associated with decreased HIV but higher HBV and HCV comorbidities in US hospital discharge records: a cross-sectional study ⬇️

scientific article published on May 24, 2012

Similar burden of type 2 diabetes among adult patients with sickle cell disease relative to African Americans in the U.S. population: a six-year population-based cohort analysis

scientific article published on 03 February 2019

Small molecules targeted to a non-catalytic "RVxF" binding site of protein phosphatase-1 inhibit HIV-1

scientific article

Symptoms and Signs of Hemochromatosis in HFE C282Y Homozygotes Identified by Screening in Primary Care. ⬇️

scholarly article

Systematic Review of Crizanlizumab: a New Parenteral Option to Reduce Vaso-occlusive Pain Crises in Patients with Sickle Cell Disease

scientific article published on 29 April 2020

Systematic review of voxelotor: a first-in-class sickle hemoglobin polymerization inhibitor for management of sickle cell disease

scientific article published on 28 April 2020

Targeting malaria with polyamines

scientific article published in November 2004

The HIF2A gene in familial erythrocytosis

The anemia of malaria infection: role of inflammatory cytokines.

scientific article published on March 2004

The association of serum ferritin and transferrin receptor concentrations with mortality in women with human immunodeficiency virus infection.

scientific article published on 16 May 2006

The celestial fire of conscience

scientific article published in September 2005

The genetics of hemoglobin A2 regulation in sickle cell anemia

scientific article

The heterozygote advantage of the Chuvash polycythemia VHLR200W mutation may be protection against anemia

scientific article

The impact of delayed treatment of uncomplicated P. falciparum malaria on progression to severe malaria: A systematic review and a pooled multicentre individual-patient meta-analysis

scientific article published on 19 October 2020

The morbidity and mortality of end stage renal disease in sickle cell disease

scientific article published on 01 March 2019

The phenotype of polycythemia due to Croatian homozygous VHL (571C>G:H191D) mutation is different from that of Chuvash polycythemia (VHL 598C>T:R200W) ⬇️

scientific article published on February 12, 2013

The relationship between the severity of hemolysis, clinical manifestations and risk of death in 415 patients with sickle cell anemia in the US and Europe

scientific article published on 14 September 2012

The sickle cell disease implementation consortium: Translating evidence-based guidelines into practice for sickle cell disease.

scientific article published on 17 October 2018

The worldwide distribution of the VHL 598C>T mutation indicates a single founding event ⬇️

scientific article published on 06 November 2003

Thrombomodulin and Endothelial Dysfunction in Sickle Cell Anemia ⬇️

scholarly article

Thrombotic Complications Are Associated with Phlebotomy Therapy in Patients with Chuvash Polycythemia ⬇️

scholarly article

Thrombotic risk in congenital erythrocytosis due to up-regulated hypoxia sensing is not associated with elevated hematocrit

scientific article published on 09 July 2019

Tibetan Enriched PKLR Variant Is Beneficial to High Altitude Adaption By Improving Oxygen Delivery ⬇️

scholarly article

Treatment target in polycythemia vera

scientific article published in April 2013

Tricuspid Regurgitation Velocity and Other Biomarkers of Mortality in Children, Adolescents and Young Adults with Sickle Cell Disease in the United States: the PUSH Study

scientific article published on 03 April 2020

Type 2 diabetes in adults with sickle cell disease: can we dive deeper? Response to Skinner et al

scientific article published on 08 May 2019

Upregulation of Tissue Factor May Contribute to Thrombosis in Polycythemia Vera and Essential Thrombocythemia ⬇️

scholarly article

Urinary orosomucoid is associated with progressive chronic kidney disease stage in patients with sickle cell anemia.

scientific article

Use of Metformin in Patients with Sickle Cell Disease

scientific article published on 09 November 2018

Utility of the Revised Cardiac Index Score for Predicting Post-Surgical Outcome in Hb SC or SBeta+ -Thalassemia Sickle Cell Disease ⬇️

scholarly article

Utility of the revised cardiac risk index for predicting postsurgical morbidity in Hb SC and Hb Sβ+-thalassemia sickle cell disease

scientific article published on 19 March 2016

Validation of a composite vascular high-risk profile for adult patients with sickle cell disease

scientific article published on 17 September 2019

Vascular complications in Chuvash polycythemia

scientific article (publication date: April 2006)

White Paper: Pathways to Progress in Newborn Screening for Sickle Cell Disease in Sub-Saharan Africa

scientific article published on 10 July 2018

Paulina is supported by:

About Paulina

Help