List of works - Dun-Xian Tan

A walnut-enriched diet reduces the growth of LNCaP human prostate cancer xenografts in nude mice

scientific article published on 11 June 2013

Accumulation of Exogenous Amyloid-BetaPeptide in Hippocampal Mitochondria Causes Their Dysfunction: A Protective Role for Melatonin ⬇️

scientific article published on May 13, 2012

Acute and delayed sulfur mustard toxicity; novel mechanisms and future studies ⬇️

scientific article published on June 1, 2008

Alterations in Lipid Levels of Mitochondrial Membranes Induced by Amyloid-ß: A Protective Role of Melatonin ⬇️

scientific article published on May 16, 2012

Alzheimer’s disease: pathological mechanisms and the beneficial role of melatonin ⬇️

scientific article published on November 23, 2011

Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in macrophages

scientific article published on August 2005

Antioxidant activity of melatonin in Chinese hamster ovarian cells: changes in cellular proliferation and differentiation

scientific article

Antioxidant properties of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK): scavenging of free radicals and prevention of protein destruction

scientific article published in January 2003

Antioxidant strategies in protection against neurodegenerative disorders

Arabidopsis serotonin N-acetyltransferase knockout mutant plants exhibit decreased melatonin and salicylic acid levels resulting in susceptibility to an avirulent pathogen

scientific article published on 23 February 2015

Beneficial actions of melatonin in the management of viral infections: a new use for this “molecular handyman”? ⬇️

scientific article published on April 18, 2012

Beneficial effects of melatonin in cardiovascular disease

scientific article published on May 2010

CSF generation by pineal gland results in a robust melatonin circadian rhythm in the third ventricle as an unique light/dark signal

scientific article

Caloric restriction, resveratrol and melatonin: Role of SIRT1 and implications for aging and related-diseases.

scientific article published on 27 March 2015

Cardiac hypertrophy and remodelling: pathophysiological consequences and protective effects of melatonin ⬇️

scientific article published on September 1, 2010

Chloroplastic biosynthesis of melatonin and its involvement in protection of plants from salt stress

scientific article published on February 2017

Chronic melatonin treatment prevents age-dependent cardiac mitochondrial dysfunction in senescence-accelerated mice.

scientific article published in January 2007

Clinical relevance of melatonin in ovarian and placental physiology: a review

scientific article published on 09 December 2013

Combination of melatonin and a peroxisome proliferator-activated receptor-gamma agonist induces apoptosis in a breast cancer cell line

scientific article published on 16 September 2008

Critical role of glutathione in melatonin enhancement of tumor necrosis factor and ionizing radiation-induced apoptosis in prostate cancer cells in vitro

scientific article

Delivery of pineal melatonin to the brain and SCN: role of canaliculi, cerebrospinal fluid, tanycytes and Virchow-Robin perivascular spaces

scientific article published on 20 February 2014

Ebola virus disease: potential use of melatonin as a treatment

scientific article published on 14 October 2014

Emergence of naturally occurring melatonin isomers and their proposed nomenclature

scientific article published on 14 February 2012

Extrapineal melatonin: sources, regulation, and potential functions.

scientific article published on 20 February 2014

Functional aspects of redox control during neuroinflammation

scientific article published on July 2010

Functional roles of melatonin in plants, and perspectives in nutritional and agricultural science ⬇️

scientific article published on October 20, 2011

Fundamental issues related to the origin of melatonin and melatonin isomers during evolution: relation to their biological functions

scientific article

Glucose: A vital toxin and potential utility of melatonin in protecting against the diabetic state ⬇️

scientific article published on November 4, 2011

Hyperglycemia-related pathophysiologic mechanisms and potential beneficial actions of melatonin

scientific article published on October 2008

Impaired mitochondrial complex III and melatonin responsive reactive oxygen species generation in kidney mitochondria of db/db mice ⬇️

scientific article published on May 27, 2011

Inhibition of neuronal nitric oxide synthase activity by N1-acetyl-5-methoxykynuramine, a brain metabolite of melatonin

scientific article published in September 2006

Inhibitory effect of melatonin on homocysteine-induced lipid peroxidation in rat brain homogenates.

scientific article

Interactions between melatonin and nicotinamide nucleotide: NADH preservation in cells and in cell-free systems by melatonin

scientific article published in September 2005

Kinetics of the neuroinflammation-oxidative stress correlation in rat brain following the injection of fibrillar amyloid-beta onto the hippocampus in vivo

scientific article published in May 2004

Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines

scientific article published on July 2009

Light at night, chronodisruption, melatonin suppression, and cancer risk: a review

scientific article published on December 2007

Light pollution, melatonin suppression and cancer growth.

scientific article

Melatonin Mitigates Mitochondrial Meltdown: Interactions with SIRT3

scholarly article by Russel J Reiter published in August 2018

Melatonin alleviates low PS I-limited carbon assimilation under elevated CO2 and enhances the cold tolerance of offspring in chlorophyll b-deficient mutant wheat

scientific article published on 17 November 2017

Melatonin and Parkinson's disease

scientific article

Melatonin and its metabolites as copper chelating agents and their role in inhibiting oxidative stress: a physicochemical analysis

scientific article published on 12 December 2014

Melatonin and mitochondrial function

scientific article published on July 2004

Melatonin and pregnancy in the human

scientific article published on April 2008

Melatonin and reproduction revisited

scientific article published on 13 May 2009

Melatonin and sirtuins: A "not-so unexpected" relationship

scientific article published on 21 January 2017

Melatonin and the circadian system: contributions to successful female reproduction

scientific article published on July 2014

Melatonin and the ovary: physiological and pathophysiological implications

scientific article published on 18 September 2008

Melatonin as a Potent and Inducible Endogenous Antioxidant: Synthesis and Metabolism

scientific article published in 2015

Melatonin as a mitochondria-targeted antioxidant: one of evolution's best ideas

scientific article

Melatonin as a natural ally against oxidative stress: a physicochemical examination.

scientific article published on August 2011

Melatonin as a naturally occurring co-substrate of quinone reductase-2, the putative MT3 melatonin membrane receptor: hypothesis and significance

scientific article published on November 2007

Melatonin as a radioprotective agent: a review

scientific article published on July 2004

Melatonin as an antioxidant: biochemical mechanisms and pathophysiological implications in humans

scientific article published on January 2003

Melatonin as an antioxidant: physiology versus pharmacology.

scientific article published in September 2005

Melatonin as an antioxidant: under promises but over delivers

scientific article

Melatonin biosynthesis in plants: multiple pathways catalyze tryptophan to melatonin in the cytoplasm or chloroplasts

scientific article published on 7 September 2016

Melatonin combats molecular terrorism at the mitochondrial level ⬇️

scientific article published on September 1, 2008

Melatonin in the biliary tract and liver: health implications

scientific article published on January 2014

Melatonin induces class A1 heat-shock factors (HSFA1s) and their possible involvement of thermotolerance in Arabidopsis

scientific article

Melatonin induces the transcripts of CBF/DREB1s and their involvement in both abiotic and biotic stresses in Arabidopsis

scientific article

Melatonin mitigates mitochondrial malfunction

scientific article

Melatonin protects the heart against both ischemia/reperfusion injury and chemotherapeutic drugs

scientific article published in January 2002

Melatonin reduces lipid peroxidation and membrane viscosity

scientific article published on 6 October 2014

Melatonin reduces mortality and oxidatively mediated hepatic and renal damage due to diquat treatment.

scientific article

Melatonin reduces oxidant damage and promotes mitochondrial respiration: implications for aging

scientific article

Melatonin relieves the neural oxidative burden that contributes to dementias

scientific article published on December 2004

Melatonin role preventing steatohepatitis and improving liver transplantation results

scientific article published on 29 March 2016

Melatonin uptake through glucose transporters: a new target for melatonin inhibition of cancer

scientific article

Melatonin's role as a co-adjuvant treatment in colonic diseases: A review

scientific article published on 2 December 2016

Melatonin's role in preventing toxin-related and sepsis-mediated hepatic damage: A review.

scientific article

Melatonin, a Full Service Anti-Cancer Agent: Inhibition of Initiation, Progression and Metastasis

scientific article

Melatonin, longevity and health in the aged: an assessment

scientific article

Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling.

scientific article published on 28 October 2011

Melatonin, xanthurenic acid, resveratrol, EGCG, vitamin C and alpha-lipoic acid differentially reduce oxidative DNA damage induced by Fenton reagents: a study of their individual and synergistic actions

scientific article published in May 2003

Melatonin-induced neuroprotection after closed head injury is associated with increased brain antioxidants and attenuated late-phase activation of NF-kappaB and AP-1.

scientific article published on 3 November 2003

Melatonin: A Versatile Protector against Oxidative DNA Damage

scientific article published on 27 February 2018

Melatonin: a hormone, a tissue factor, an autocoid, a paracoid, and an antioxidant vitamin

scientific article

Melatonin: a multitasking molecule

scientific article published on January 2010

Melatonin: a novel protective agent against oxidative injury of the ischemic/reperfused heart

scientific article

Melatonin: an ancient molecule that makes oxygen metabolically tolerable.

scientific article published on 14 August 2015

Melatonin: an established antioxidant worthy of use in clinical trials.

scientific article

Melatonin: detoxification of oxygen and nitrogen-based toxic reactants.

scientific article published on January 2003

Melatonin: exceeding expectations

scientific article published on September 2014

Melatonin: reducing the toxicity and increasing the efficacy of drugs

scientific article (publication date: October 2002)

Mitochondria and chloroplasts as the original sites of melatonin synthesis: a hypothesis related to melatonin's primary function and evolution in eukaryotes.

scientific article

Mitochondria: Central Organelles for Melatonin's Antioxidant and Anti-Aging Actions

scientific article published on 24 February 2018

N-Acetylserotonin and 6-Hydroxymelatonin against Oxidative Stress: Implications for the Overall Protection Exerted by Melatonin

scientific article

Natural Variation in Banana Varieties Highlights the Role of Melatonin in Postharvest Ripening and Quality

scientific article published on 27 October 2017

Neurotoxins: Free Radical Mechanisms and Melatonin Protection ⬇️

scientific article published on September 1, 2010

Novel rhythms of N1-acetyl-N2-formyl-5-methoxykynuramine and its precursor melatonin in water hyacinth: importance for phytoremediation

scientific article published on 21 February 2007

Obesity and metabolic syndrome: Association with chronodisruption, sleep deprivation, and melatonin suppression ⬇️

scientific article published on June 13, 2011

On the free radical scavenging activities of melatonin's metabolites, AFMK and AMK.

scientific article published on 23 September 2012

On the significance of an alternate pathway of melatonin synthesis via 5-methoxytryptamine: comparisons across species

scientific article published on 26 April 2016

One molecule, many derivatives: a never-ending interaction of melatonin with reactive oxygen and nitrogen species?

scientific article

Orally administered melatonin reduces oxidative stress and proinflammatory cytokines induced by amyloid-beta peptide in rat brain: a comparative, in vivo study versus vitamin C and E.

scientific article published in September 2003

Oxidative damage to catalase induced by peroxyl radicals: functional protection by melatonin and other antioxidants

scientific article

Peripheral reproductive organ health and melatonin: ready for prime time

scientific article published on 2 April 2013

Pharmacological utility of melatonin in reducing oxidative cellular and molecular damage.

scientific article published on March 2004

Physiological ischemia/reperfusion phenomena and their relation to endogenous melatonin production: a hypothesis

scientific article

Phytomelatonin: a review.

scientific article

Phytomelatonin: assisting plants to survive and thrive

scientific article

Phytoremediative capacity of plants enriched with melatonin

scientific article published in November 2007

Pineal Calcification, Melatonin Production, Aging, Associated Health Consequences and Rejuvenation of the Pineal Gland.

scientific article published on 31 January 2018

Potential benefits of melatonin in organ transplantation: a review

scientific article

Predominance of 2-hydroxymelatonin over melatonin in plants

scientific article published on 30 August 2015

Protective effects of melatonin in experimental free radical-related ocular diseases.

scientific article

Protective effects of melatonin in reducing oxidative stress and in preserving the fluidity of biological membranes: a review

scientific article published on 07 March 2014

Purslane: a plant source of omega-3 fatty acids and melatonin

scientific article

Radical-trapping and preventive antioxidant effects of 2-hydroxymelatonin and 4-hydroxymelatonin: Contributions to the melatonin protection against oxidative stress.

scientific article

Reactive oxygen species and the hypomotility of the gall bladder as targets for the treatment of gallstones with melatonin: a review

scientific article

Role of CSF in the transport of melatonin

scientific article

Role of melatonin in metabolic regulation

scientific article published on December 2009

Role of melatonin in the epigenetic regulation of breast cancer

scientific article published on July 2008

Role of melatonin in the regulation of autophagy and mitophagy: a review

scientific article published on May 2012

Role of melatonin on production and preservation of gametes and embryos: a brief review.

scientific article published on February 2014

Significance of high levels of endogenous melatonin in Mammalian cerebrospinal fluid and in the central nervous system

scientific article

The changing biological roles of melatonin during evolution: from an antioxidant to signals of darkness, sexual selection and fitness

scientific article published on 21 December 2009

The disaster in Japan: utility of melatonin in providing protection against ionizing radiation ⬇️

scientific article published on March 31, 2011

The universal nature, unequal distribution and antioxidant functions of melatonin and its derivatives

scientific article published on March 2013

Urgent search for safe and effective treatments of severe acute respiratory syndrome: is melatonin a promising candidate drug?

scientific article

What constitutes a physiological concentration of melatonin?

scientific article

When melatonin gets on your nerves: its beneficial actions in experimental models of stroke

scientific article

When the circadian clock becomes a ticking time bomb.

scientific article published on 24 September 2012

List of works by Dun-Xian Tan

A walnut-enriched diet reduces the growth of LNCaP human prostate cancer xenografts in nude mice

Accumulation of Exogenous Amyloid-BetaPeptide in Hippocampal Mitochondria Causes Their Dysfunction: A Protective Role for Melatonin ⬇️

Acute and delayed sulfur mustard toxicity; novel mechanisms and future studies ⬇️

Alterations in Lipid Levels of Mitochondrial Membranes Induced by Amyloid-ß: A Protective Role of Melatonin ⬇️

Alzheimer’s disease: pathological mechanisms and the beneficial role of melatonin ⬇️

Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in macrophages

Antioxidant activity of melatonin in Chinese hamster ovarian cells: changes in cellular proliferation and differentiation

Antioxidant properties of the melatonin metabolite N1-acetyl-5-methoxykynuramine (AMK): scavenging of free radicals and prevention of protein destruction

Antioxidant strategies in protection against neurodegenerative disorders

Arabidopsis serotonin N-acetyltransferase knockout mutant plants exhibit decreased melatonin and salicylic acid levels resulting in susceptibility to an avirulent pathogen

Beneficial actions of melatonin in the management of viral infections: a new use for this “molecular handyman”? ⬇️

Beneficial effects of melatonin in cardiovascular disease

CSF generation by pineal gland results in a robust melatonin circadian rhythm in the third ventricle as an unique light/dark signal

Caloric restriction, resveratrol and melatonin: Role of SIRT1 and implications for aging and related-diseases.

Cardiac hypertrophy and remodelling: pathophysiological consequences and protective effects of melatonin ⬇️

Chloroplastic biosynthesis of melatonin and its involvement in protection of plants from salt stress

Chronic melatonin treatment prevents age-dependent cardiac mitochondrial dysfunction in senescence-accelerated mice.

Clinical relevance of melatonin in ovarian and placental physiology: a review

Combination of melatonin and a peroxisome proliferator-activated receptor-gamma agonist induces apoptosis in a breast cancer cell line

Critical role of glutathione in melatonin enhancement of tumor necrosis factor and ionizing radiation-induced apoptosis in prostate cancer cells in vitro

Delivery of pineal melatonin to the brain and SCN: role of canaliculi, cerebrospinal fluid, tanycytes and Virchow-Robin perivascular spaces

Ebola virus disease: potential use of melatonin as a treatment

Emergence of naturally occurring melatonin isomers and their proposed nomenclature

Extrapineal melatonin: sources, regulation, and potential functions.

Functional aspects of redox control during neuroinflammation

Functional roles of melatonin in plants, and perspectives in nutritional and agricultural science ⬇️

Fundamental issues related to the origin of melatonin and melatonin isomers during evolution: relation to their biological functions

Glucose: A vital toxin and potential utility of melatonin in protecting against the diabetic state ⬇️

Hyperglycemia-related pathophysiologic mechanisms and potential beneficial actions of melatonin

Impaired mitochondrial complex III and melatonin responsive reactive oxygen species generation in kidney mitochondria of db/db mice ⬇️

Inhibition of neuronal nitric oxide synthase activity by N1-acetyl-5-methoxykynuramine, a brain metabolite of melatonin

Inhibitory effect of melatonin on homocysteine-induced lipid peroxidation in rat brain homogenates.

Interactions between melatonin and nicotinamide nucleotide: NADH preservation in cells and in cell-free systems by melatonin

Kinetics of the neuroinflammation-oxidative stress correlation in rat brain following the injection of fibrillar amyloid-beta onto the hippocampus in vivo

Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines

Light at night, chronodisruption, melatonin suppression, and cancer risk: a review

Light pollution, melatonin suppression and cancer growth.

Melatonin Mitigates Mitochondrial Meltdown: Interactions with SIRT3

Melatonin alleviates low PS I-limited carbon assimilation under elevated CO2 and enhances the cold tolerance of offspring in chlorophyll b-deficient mutant wheat

Melatonin and Parkinson's disease

Melatonin and its metabolites as copper chelating agents and their role in inhibiting oxidative stress: a physicochemical analysis

Melatonin and mitochondrial function

Melatonin and pregnancy in the human

Melatonin and reproduction revisited

Melatonin and sirtuins: A "not-so unexpected" relationship

Melatonin and the circadian system: contributions to successful female reproduction

Melatonin and the ovary: physiological and pathophysiological implications

Melatonin as a Potent and Inducible Endogenous Antioxidant: Synthesis and Metabolism

Melatonin as a mitochondria-targeted antioxidant: one of evolution's best ideas

Melatonin as a natural ally against oxidative stress: a physicochemical examination.

Melatonin as a naturally occurring co-substrate of quinone reductase-2, the putative MT3 melatonin membrane receptor: hypothesis and significance

Melatonin as a radioprotective agent: a review

Melatonin as an antioxidant: biochemical mechanisms and pathophysiological implications in humans

Melatonin as an antioxidant: physiology versus pharmacology.

Melatonin as an antioxidant: under promises but over delivers

Melatonin biosynthesis in plants: multiple pathways catalyze tryptophan to melatonin in the cytoplasm or chloroplasts

Melatonin combats molecular terrorism at the mitochondrial level ⬇️

Melatonin in the biliary tract and liver: health implications

Melatonin induces class A1 heat-shock factors (HSFA1s) and their possible involvement of thermotolerance in Arabidopsis

Melatonin induces the transcripts of CBF/DREB1s and their involvement in both abiotic and biotic stresses in Arabidopsis

Melatonin mitigates mitochondrial malfunction

Melatonin protects the heart against both ischemia/reperfusion injury and chemotherapeutic drugs

Melatonin reduces lipid peroxidation and membrane viscosity

Melatonin reduces mortality and oxidatively mediated hepatic and renal damage due to diquat treatment.

Melatonin reduces oxidant damage and promotes mitochondrial respiration: implications for aging

Melatonin relieves the neural oxidative burden that contributes to dementias

Melatonin role preventing steatohepatitis and improving liver transplantation results

Melatonin uptake through glucose transporters: a new target for melatonin inhibition of cancer

Melatonin's role as a co-adjuvant treatment in colonic diseases: A review

Melatonin's role in preventing toxin-related and sepsis-mediated hepatic damage: A review.

Melatonin, a Full Service Anti-Cancer Agent: Inhibition of Initiation, Progression and Metastasis

Melatonin, longevity and health in the aged: an assessment

Melatonin, the circadian multioscillator system and health: the need for detailed analyses of peripheral melatonin signaling.

Melatonin, xanthurenic acid, resveratrol, EGCG, vitamin C and alpha-lipoic acid differentially reduce oxidative DNA damage induced by Fenton reagents: a study of their individual and synergistic actions

Melatonin-induced neuroprotection after closed head injury is associated with increased brain antioxidants and attenuated late-phase activation of NF-kappaB and AP-1.

Melatonin: A Versatile Protector against Oxidative DNA Damage

Melatonin: a hormone, a tissue factor, an autocoid, a paracoid, and an antioxidant vitamin

Melatonin: a multitasking molecule

Melatonin: a novel protective agent against oxidative injury of the ischemic/reperfused heart