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List of works by Evelyn Sattlegger

A Rapid Extraction Method for mammalian cell cultures, suitable for quantitative immunoblotting analysis of proteins, including phosphorylated GCN2 and eIF2α.

scientific article

Biophysical characterization of Gir2, a highly acidic protein of Saccharomyces cerevisiae with anomalous electrophoretic behavior.

scientific article published in January 2004

Cost-effective and rapid lysis of Saccharomyces cerevisiae cells for quantitative western blot analysis of proteins, including phosphorylated eIF2α.

scientific article published in June 2017

Damaging de novo missense variants in EEF1A2 lead to a developmental and degenerative epileptic-dyskinetic encephalopathy

scientific article published on 20 March 2020

Domain II of the translation elongation factor eEF1A is required for Gcn2 kinase inhibition

scientific article published on 02 May 2020

Evidence that Yih1 resides in a complex with ribosomes ⬇️

scientific article published on April 10, 2012

Evidence that eukaryotic translation elongation factor 1A (eEF1A) binds the Gcn2 protein C terminus and inhibits Gcn2 activity

scientific article

Evolutionarily conserved IMPACT impairs various stress responses that require GCN1 for activating the eIF2 kinase GCN2.

scientific article

Experimentally based structural model of Yih1 provides insight into its function in controlling the key translational regulator Gcn2

scientific article published on 06 November 2020

Gcn1 and actin binding to Yih1: implications for activation of the eIF2 kinase GCN2.

scientific article

Gcn1 contacts the small ribosomal protein Rps10, which is required for full activation of the protein kinase Gcn2.

scientific article

IMPACT, a protein preferentially expressed in the mouse brain, binds GCN1 and inhibits GCN2 activation

scientific journal article

Imprinted and ancient gene: a potential mediator of cancer cell survival during tryptophan deprivation

article

Interplay between GCN2 and GCN4 expression, translation elongation factor 1 mutations and translational fidelity in yeast.

scientific article

Keeping the eIF2 alpha kinase Gcn2 in check

scientific article published on 13 April 2014

Overexpression of eukaryotic translation elongation factor 3 impairs Gcn2 protein activation

scientific article

Persistent contamination of Salmonella, Campylobacter, Escherichia coli, and Staphylococcus aureus at a broiler farm in New Zealand

scientific article published on 13 November 2019

Perturbations in actin dynamics reconfigure protein complexes that modulate GCN2 activity and promote an eIF2 response.

scientific article published on 16 November 2016

Polyribosome binding by GCN1 is required for full activation of eukaryotic translation initiation factor 2{alpha} kinase GCN2 during amino acid starvation

scientific article

Recognition of a structural domain (RWDBD) in Gcn1 proteins that interacts with the RWD domain containing proteins.

scientific article

Semi-quantitative colony immunoassay for determining and optimizing protein expression in Saccharomyces cerevisiae and Escherichia coli.

scientific article published on 28 October 2013

The Gcn2 Regulator Yih1 Interacts with the Cyclin Dependent Kinase Cdc28 and Promotes Cell Cycle Progression through G2/M in Budding Yeast.

scientific article published on 15 July 2015

Transcriptional defect of an inherited NKX2-5 haplotype comprising a SNP, a nonsynonymous and a synonymous mutation, associated with human congenital heart disease

scientific article

YIH1 is an actin-binding protein that inhibits protein kinase GCN2 and impairs general amino acid control when overexpressed

scientific article

Yeast as a Model to Understand Actin-Mediated Cellular Functions in Mammals-Illustrated with Four Actin Cytoskeleton Proteins

scientific article published on 10 March 2020

Yeast studies reveal moonlighting functions of the ancient actin cytoskeleton

scientific article

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