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List of works by Hiroto Kuwabara

11C-JHU75528: a radiotracer for PET imaging of CB1 cannabinoid receptors

scientific article published in October 2006

18F-ASEM, a radiolabeled antagonist for imaging the α7-nicotinic acetylcholine receptor with PET.

scientific article published on 20 February 2014

18F-FPEB, a PET radiopharmaceutical for quantifying metabotropic glutamate 5 receptors: a first-in-human study of radiochemical safety, biokinetics, and radiation dosimetry

scientific article

18F-XTRA PET for enhanced imaging of the extrathalamic α4β2 nicotinic acetylcholine receptor

scientific article published in March 2018

Characterization of 3 Novel Tau Radiopharmaceuticals, 11C-RO-963, 11C-RO-643, and 18F-RO-948, in Healthy Controls and in Alzheimer Subjects

scientific article published on 04 May 2018

Derivatives of (-)-7-methyl-2-(5-(pyridinyl)pyridin-3-yl)-7-azabicyclo[2.2.1]heptane are potential ligands for positron emission tomography imaging of extrathalamic nicotinic acetylcholine receptors

scientific article

Development of a High-Affinity PET Radioligand for Imaging Cannabinoid Subtype 2 Receptor.

scientific article

Discovery of (-)-7-methyl-2-exo-[3'-(6-[18F]fluoropyridin-2-yl)-5'-pyridinyl]-7-azabicyclo[2.2.1]heptane, a radiolabeled antagonist for cerebral nicotinic acetylcholine receptor (alpha4beta2-nAChR) with optimal positron emission tomography imaging p

scientific article

Dissociative changes in the Bmax and KD of dopamine D2/D3 receptors with aging observed in functional subdivisions of the striatum: a revisit with an improved data analysis method

scientific article

Dose-dependent, saturable occupancy of the metabotropic glutamate subtype 5 receptor by fenobam as measured with [(11) C]ABP688 PET imaging

scientific article

Erratum: Increased Occupancy of Dopamine Receptors in Human Striatum during Cue-Elicited Cocaine Craving

scholarly article by Dean F Wong et al published 14 December 2006 in Neuropsychopharmacology

Human brain imaging of α7 nAChR with [(18)F]ASEM: a new PET radiotracer for neuropsychiatry and determination of drug occupancy

scientific article published on October 2014

Identification of Three Novel Radiotracers for Imaging Aggregated Tau in Alzheimer's Disease with Positron Emission Tomography.

scientific article published on 27 June 2017

Imaging α4β2 Nicotinic Acetylcholine Receptors (nAChRs) in Baboons with [18F]XTRA, a Radioligand with Improved Specific Binding in Extra-Thalamic Regions.

scientific article published on 26 August 2016

Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving

scientific article published on 13 September 2006

Increased synaptic dopamine in the putamen in restless legs syndrome

scientific article

Influence of OPRM1 Asn40Asp variant (A118G) on [11C]carfentanil binding potential: preliminary findings in human subjects

scientific article published on 8 March 2012

Mechanisms of dopaminergic and serotonergic neurotransmission in Tourette syndrome: clues from an in vivo neurochemistry study with PET.

scientific article published on 7 November 2007

New synthesis and evaluation of enantiomers of 7-methyl-2-exo-(3'-iodo-5'-pyridinyl)-7-azabicyclo[2.2.1]heptane as stereoselective ligands for PET imaging of nicotinic acetylcholine receptors

scientific article

PET Brain imaging of α7-nAChR with [18F]ASEM: Reproducibility, occupancy, receptor density, and changes in schizophrenia

scientific article published on 7 March 2018

PET Imaging of High-Affinity α4β2 Nicotinic Acetylcholine Receptors in Humans with 18F-AZAN, a Radioligand with Optimal Brain Kinetics ⬇️

scientific article published on June 25, 2013

PET Imaging of Nicotinic Acetylcholine Receptors in Baboons with 18F-AZAN, a Radioligand with Improved Brain Kinetics ⬇️

scientific article published on December 15, 2011

Persistent cognitive and dopamine transporter deficits in abstinent methamphetamine users

scientific article published in February 2008

Preclinical Evaluation of (18)F-RO6958948, (11)C-RO6931643 and (11)C-RO6924963 as Novel Radiotracers for Imaging Aggregated Tau in AD with Positron Emission Tomography

scientific article published on 28 September 2017

Quantification of cerebral cannabinoid receptors subtype 1 (CB1) in healthy subjects and schizophrenia by the novel PET radioligand [11C]OMAR.

scientific article published on 18 April 2010

Recent PET radioligands with optimal brain kinetics for imaging nicotinic acetylcholine receptors

scientific article published on March 2013

Synthesis and biological evaluation of novel carbon-11 labeled pyridyl ethers: candidate ligands for in vivo imaging of alpha4beta2 nicotinic acetylcholine receptors (alpha4beta2-nAChRs) in the brain with positron emission tomography

scientific article published on 15 May 2009

Synthesis and evaluation of new radioligands [(11)C]A-833834 and [(11)C]A-752274 for positron-emission tomography of α7-nicotinic acetylcholine receptors

scientific article

The distribution of the alpha7 nicotinic acetylcholine receptor in healthy aging: An in vivo positron emission tomography study with [18F]ASEM.

scientific article published on 6 October 2017

The dopamine transporter is decreased in the striatum of subjects with restless legs syndrome

scientific article

The relationship of varenicline agonism of α4β2 nicotinic acetylcholine receptors and nicotine-induced dopamine release in nicotine dependent humans

scientific article published on 16 May 2019

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