Search filters

List of works by Shuofeng Yuan

A Large-scale Drug Repositioning Survey for SARS-CoV-2 Antivirals

scientific article published on 18 April 2020

A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster

scientific article published in February 2020

An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses

scientific article published on 25 May 2022

Antibody-Dependent Cell-Mediated Cytotoxicity Epitopes on the Hemagglutinin Head Region of Pandemic H1N1 Influenza Virus Play Detrimental Roles in H1N1-Infected Mice

scientific article

Broad-Spectrum Host-Based Antivirals Targeting the Interferon and Lipogenesis Pathways as Potential Treatment Options for the Pandemic Coronavirus Disease 2019 (COVID-19)

scientific article published on 10 June 2020

Characterization of the Lipidomic Profile of Human Coronavirus-Infected Cells: Implications for Lipid Metabolism Remodeling upon Coronavirus Replication

scientific article published on 16 January 2019

Clofazimine is a broad-spectrum coronavirus inhibitor that antagonizes SARS-CoV-2 replication in primary human cell culture and hamsters

scientific article published on 07 October 2020

Comparative immunological evaluation of recombinant Salmonella Typhimurium strains expressing model antigens as live oral vaccines

scientific article

Comparative replication and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo study with implications for the pathogenesis of COVID-19

scientific article published on 09 April 2020

Differentiated human airway organoids to assess infectivity of emerging influenza virus

article published in the Proceedings of the National Academy of Sciences of the United States of America

Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing

scientific article published on 24 July 2020

Dual-functional peptide with defective interfering genes effectively protects mice against avian and seasonal influenza.

scientific article

Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan

scientific article published on 28 January 2020

Identification and characterization of GLDC as host susceptibility gene to severe influenza

article

Identification of a small-molecule inhibitor of influenza virus via disrupting the subunits interaction of the viral polymerase

scientific article published on 21 November 2015

In silico structure-based discovery of a SARS-CoV-2 main protease inhibitor

scientific article published on 10 April 2021

Inhibitors of Influenza A Virus Polymerase

scientific article published on 22 January 2018

Intranasal administration of a single dose of a candidate live attenuated vaccine derived from an NSP16-deficient SARS-CoV-2 strain confers sterilizing immunity in animals

scientific article published on 29 March 2022

Large-scale sequence analysis reveals novel human-adaptive markers in PB2 segment of seasonal influenza A viruses.

scientific article

Metabolic Profiling Reveals Significant Perturbations of Intracellular Glucose Homeostasis in Enterovirus-Infected Cells

scientific article published on 23 July 2020

Metallodrug ranitidine bismuth citrate suppresses SARS-CoV-2 replication and relieves virus-associated pneumonia in Syrian hamsters

scientific article published on 07 October 2020

Middle East Respiratory Syndrome Coronavirus ORF8b Accessory Protein Suppresses Type I IFN Expression by Impeding HSP70-Dependent Activation of IRF3 Kinase IKKε

scientific article published on 03 August 2020

Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells

scientific article published in Journal of Biological Chemistry

Novel antiviral activity and mechanism of bromocriptine as a Zika virus NS2B-NS3 protease inhibitor

scientific article (publication date: February 2017)

Novel residues in the PA protein of avian influenza H7N7 virus affect virulence in mammalian hosts

scientific article published on 12 August 2016

PB2 substitutions V598T/I increase the virulence of H7N9 influenza A virus in mammals

scientific article

Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies

scientific article published on 25 February 2021

SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamsters

scientific article published on 09 May 2022

SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target

scientific article published in Nature Communications

Screening of an FDA-Approved Drug Library with a Two-Tier System Identifies an Entry Inhibitor of Severe Fever with Thrombocytopenia Syndrome Virus

scientific article published on 25 April 2019

Severe fever with thrombocytopenia syndrome virus (SFTSV)-host interactome screen identifies viral nucleoprotein-associated host factors as potential antiviral targets

scientific article published on 01 October 2021

Simulation of the clinical and pathological manifestations of Coronavirus Disease 2019 (COVID-19) in golden Syrian hamster model: implications for disease pathogenesis and transmissibility

scientific article published on 26 March 2020

Structure-based discovery of clinically approved drugs as Zika virus NS2B-NS3 protease inhibitors that potently inhibit Zika virus infection in vitro and in vivo

scientific article published on 13 July 2017

Surgical mask partition reduces the risk of non-contact transmission in a golden Syrian hamster model for Coronavirus Disease 2019 (COVID-19)

scientific article published on 30 May 2020

Viruses harness YxxØ motif to interact with host AP2M1 for replication: A vulnerable broad-spectrum antiviral target

scientific article published on 28 August 2020

Paulina is supported by:

About Paulina

Help