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List of works by Digna R. Velez Edwards

2530 Relationship between preexisting pain and completion of a community-based wellness program

article published in 2018

A Polygenic and Phenotypic Risk Prediction for Polycystic Ovary Syndrome Evaluated by Phenome-Wide Association Studies

scientific article published on 9 January 2020

A Trans-Ethnic Genome-Wide Association Study of Uterine Fibroids.

scientific article published on 12 June 2019

A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk

article

A balanced accuracy function for epistasis modeling in imbalanced datasets using multifactor dimensionality reduction.

scientific article

A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM).

scientific article

A genome-wide association study identifies variants in KCNIP4 associated with ACE inhibitor-induced cough

scientific article

A genome-wide association study meta-analysis of clinical fracture in 10,012 African American women

scientific article

A genome-wide association study of polycystic ovary syndrome identified from electronic health records

scientific article published on 11 April 2020

A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry

scientific article

A multi-stage genome-wide association study of uterine fibroids in African Americans

scientific article

Admixture mapping identifies a locus at 15q21.2-22.3 associated with keloid formation in African Americans.

scientific article

Admixture mapping of pelvic organ prolapse in African Americans from the Women's Health Initiative Hormone Therapy trial

scientific article

Admixture mapping of uterine fibroid size and number in African American women

scientific article published in December 2017

African genetic ancestry interacts with body mass index to modify risk for uterine fibroids.

scientific article

Alcohol Use in Pregnancy and Miscarriage: A Systematic Review and Meta-Analysis

scientific article published on 03 July 2019

Analyses of germline variants associated with ovarian cancer survival identify functional candidates at the 1q22 and 19p12 outcome loci

scientific article published on 15 June 2017

Analysis of potential protein-modifying variants in 9000 endometriosis patients and 150000 controls of European ancestry

scientific article published on 12 September 2017

Angiotensinogen promoter sequence variants in essential hypertension.

scientific article published in December 2006

Association between First Trimester Antidepressant Use and Risk of Spontaneous Abortion

scientific article published on 25 July 2019

Association of SLC11A1 with tuberculosis and interactions with NOS2A and TLR2 in African-Americans and Caucasians.

scientific article

Association of Thyroid Function Genetic Predictors With Atrial Fibrillation: A Phenome-Wide Association Study and Inverse-Variance Weighted Average Meta-analysis

scientific article published on 01 February 2019

Association of age at menarche with increasing number of fibroids in a cohort of women who underwent standardized ultrasound assessment.

scientific article published on 30 June 2013

Association of gene coding variation and resting metabolic rate in a multi-ethnic sample of children and adults

scientific article

Association of genetic variants, ethnicity and preterm birth with amniotic fluid cytokine concentrations

scientific article published in March 2010

Association of uterine fibroids with birthweight and gestational age

scientific article published on 01 July 2020

BET1L and TNRC6B associate with uterine fibroid risk among European Americans

scientific article published on 19 April 2013

CD4 intragenic SNPs associate with HIV-2 plasma viral load and CD4 count in a community-based study from Guinea-Bissau, West Africa

scientific article published on January 2011

CLCNKB-T481S and essential hypertension in a Ghanaian population

scientific article published on February 2009

Characterizing the clinical and genetic spectrum of polycystic ovary syndrome in electronic health records

scientific article published on 22 September 2020

Correction: Interleukin 12B (IL12B) Genetic Variation and Pulmonary Tuberculosis: A Study of Cohorts from The Gambia, Guinea-Bissau, United States and Argentina

scientific article published in PLoS ONE

Correction: Interleukin 12B (IL12B) Genetic Variation and Pulmonary Tuberculosis: A Study of Cohorts from The Gambia, Guinea-Bissau, United States and Argentina

Correction: Interleukin 12B (IL12B) Genetic Variation and Pulmonary Tuberculosis: A Study of Cohorts from The Gambia, Guinea-Bissau, United States and Argentina

Correction: Interleukin 12B (IL12B) Genetic Variation and Pulmonary Tuberculosis: A Study of Cohorts from The Gambia, Guinea-Bissau, United States and Argentina.

scientific article

Correction: Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.

scientific article

Cross-cancer genome-wide association study of endometrial cancer and epithelial ovarian cancer identifies genetic risk regions associated with risk of both cancers

scientific article published on 03 November 2020

Cytokine gene polymorphisms and the outcome of invasive candidiasis: a prospective cohort study

scientific article published on 5 December 2011

DC-SIGN (CD209), pentraxin 3 and vitamin D receptor gene variants associate with pulmonary tuberculosis risk in West Africans.

scientific article published on 5 July 2007

Data simulation software for whole-genome association and other studies in human genetics.

scientific article

Deep learning predicts extreme preterm birth from electronic health records

scientific article published on 31 October 2019

Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals

scientific article published on 23 November 2020

Enhancing uterine fibroid research through utilization of biorepositories linked to electronic medical record data

scientific article

Epiregulin (EREG) and human V-ATPase (TCIRG1): genetic variation, ethnicity and pulmonary tuberculosis susceptibility in Guinea-Bissau and The Gambia.

scientific article published on 5 June 2014

Equity in Health: Consideration of Race and Ethnicity in Precision Medicine

scientific article published on 22 July 2020

Erratum to: A multi-stage genome-wide association study of uterine fibroids in African Americans

scientific article published on 4 October 2017

Estimating Uterine Fibroid SNP-Based Heritability in European American Women with Imaging-Confirmed Fibroids

scientific article published on 03 September 2019

Ethnic differences in interleukin 6 (IL-6) and IL6 receptor genes in spontaneous preterm birth and effects on amniotic fluid protein levels

scientific article published on 7 March 2007

Ethnic differences in key candidate genes for spontaneous preterm birth: TNF-alpha and its receptors

scientific article published on 17 October 2006

Evaluating risk factors for differences in fibroid size and number using a large electronic health record population

scientific article published on 11 May 2018

Evaluating the role of race and medication in protection of uterine fibroids by type 2 diabetes exposure

scientific article

Evaluation of vitamin D biosynthesis and pathway target genes reveals UGT2A1/2 and EGFR polymorphisms associated with epithelial ovarian cancer in African American Women

article

Evidence of selection as a cause for racial disparities in fibroproliferative disease.

scientific article published on 8 August 2017

Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits

scientific article

Exploring the performance of Multifactor Dimensionality Reduction in large scale SNP studies and in the presence of genetic heterogeneity among epistatic disease models

scientific article published on 15 December 2008

Expression Quantitative Trait Locus Mapping Studies in Mid-secretory Phase Endometrial Cells Identifies HLA-F and TAP2 as Fecundability-Associated Genes

scientific article

First-trimester antihistamine exposure and risk of spontaneous abortion or preterm birth.

scientific article published on May 2014

First-trimester bleeding characteristics associate with increased risk of preterm birth: data from a prospective pregnancy cohort

scientific article

Functional BSND variants in essential hypertension.

scientific article published in November 2007

Gene-based evaluation of low-frequency variation and genetically-predicted gene expression impacting risk of keloid formation.

scientific article

Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women’s Health Initiative SHARe Study ⬇️

scientific article published on November 29, 2012

Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk

scientific article published on 17 December 2018

Genetic Determinants of Pelvic Organ Prolapse among African American and Hispanic Women in the Women's Health Initiative.

scientific article published on 6 November 2015

Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scientific article published on 17 September 2018

Genetic analysis of over one million people identifies 535 novel loci for blood pressure

Genetic epidemiology of pelvic organ prolapse: a systematic review

scientific article

Genetic regulation of amniotic fluid TNF-alpha and soluble TNF receptor concentrations affected by race and preterm birth

scientific article published on 21 September 2008

Genetic variation in the dectin-1/CARD9 recognition pathway and susceptibility to candidemia

scientific article

Genome-Wide Association Study of Serum Creatinine Levels during Vancomycin Therapy

scientific article published on June 2015

Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

scientific article published in September 2016

Genome-wide association analysis identifies 27 novel loci associated with uterine leiomyomata revealing common genetic origins with endometriosis

Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations

scientific article

Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis

scientific article published on 24 October 2019

Genome-wide association and linkage study in the Amish detects a novel candidate late-onset Alzheimer disease gene

scientific journal article

Genomic analyses for age at menarche identify 389 independent signals and indicate BMI-independent effects of puberty timing on cancer susceptibility

scientific article published on 23 September 2016

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

scientific article published on 24 April 2017

Geographic ancestry and markers of preterm birth

scientific article published on January 2010

Gestational Age at Arrest of Development: An Alternative Approach for Assigning Time at Risk in Studies of Time-Varying Exposures and Miscarriage

scientific article published on 01 March 2019

Gestational diabetes mellitus is associated with increased CD163 expression and iron storage in the placenta

scientific article published on 09 July 2018

HTR1B, ADIPOR1, PPARGC1A, and CYP19A1 and obesity in a cohort of Caucasians and African Americans: an evaluation of gene-environment interactions and candidate genes

scientific article published on 20 November 2011

Haplotype diversity in four genes (CLCNKA, CLCNKB, BSND, NEDD4L) involved in renal salt reabsorption

scientific article

Heritability and genome-wide association study of benign prostatic hyperplasia (BPH) in the eMERGE network

scientific article published on 15 April 2019

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

scientific article

Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes

scientific article

Interleukin 12B (IL12B) genetic variation and pulmonary tuberculosis: a study of cohorts from The Gambia, Guinea-Bissau, United States and Argentina

scientific article

Interleukin-6 (IL-6) and receptor (IL6-R) gene haplotypes associate with amniotic fluid protein concentrations in preterm birth.

scientific article published on 14 February 2008

Interpregnancy Interval After Pregnancy Loss and Risk of Repeat Miscarriage.

scientific article

Inverse association of female hormone replacement therapy with age-related macular degeneration and interactions with ARMS2 polymorphisms

scientific article

Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases

scientific article

Large-scale genome-wide association meta-analysis of endometriosis reveals 13 novel loci and genetically-associated comorbidity with other pain conditions

Learning to Identify Severe Maternal Morbidity from Electronic Health Records

scientific article published on 01 August 2019

Leiomyomas in Pregnancy and Spontaneous Abortion: A Systematic Review and Meta-analysis.

scientific article published on 6 October 2017

Leveraging Electronic Health Records to Learn Progression Path for Severe Maternal Morbidity

scientific article published on 01 August 2019

Linkage and association of successful aging to the 6q25 region in large Amish kindreds

scientific article published on 07 July 2012

MCP1 SNPs and pulmonary tuberculosis in cohorts from West Africa, the USA and Argentina: lack of association or epistasis with IL12B polymorphisms

scientific article

Management of Uterine Fibroids

scientific article published on 22 February 2019

Mapping eGFR loci to the renal transcriptome and phenome in the VA Million Veteran Program

scientific article published on 26 August 2019

Maternal Western-style diet affects offspring islet composition and function in a non-human primate model of maternal over-nutrition

scientific article published on 12 April 2019

Maternal and fetal genetic associations of PTGER3 and PON1 with preterm birth

scientific article published in 2010

Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci

scientific article published on 12 September 2016

Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism

scientific article

Mitochondrial DNA variant A4917G, smoking and spontaneous preterm birth

scientific article published on 06 November 2007

Multilocus interactions at maternal tumor necrosis factor-alpha, tumor necrosis factor receptors, interleukin-6 and interleukin-6 receptor genes predict spontaneous preterm labor in European-American women

scientific article published on 01 June 2006

Nonsteroidal Anti-inflammatory Drug Interaction with Prostacyclin Synthase Protects from Miscarriage

scientific article

Obesity and pelvic organ prolapse: a systematic review and meta-analysis of observational studies

scientific article

PTX3 genetic variation and dizygotic twinning in the Gambia: could pleiotropy with innate immunity explain common dizygotic twinning in Africa?

scientific article published on 27 July 2012

Parkinson disease loci in the mid-western Amish

scientific journal article

Patterns of cytokine profiles differ with pregnancy outcome and ethnicity.

scientific article published on 16 May 2008

Periconceptional Over-the-Counter Nonsteroidal Anti-Inflammatory Drug Exposure and Risk for Spontaneous Abortion

Periconceptional over-the-counter nonsteroidal anti-inflammatory drug exposure and risk for spontaneous abortion

scientific article

Phenotype risk scores identify patients with unrecognized Mendelian disease patterns

scientific article published in Science

Phenotyping clinical disorders: lessons learned from pelvic organ prolapse.

scientific article published on 27 November 2012

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

scientific article

Polymorphisms in maternal and fetal genes encoding for proteins involved in extracellular matrix metabolism alter the risk for small-for-gestational-age

scientific article

Population Stratification in Genetic Association Studies

scientific article published on 18 October 2017

Preterm birth in Caucasians is associated with coagulation and inflammation pathway gene variants

scientific article published in 2008

Progestogens for Prevention of Preterm Birth

Progestogens for preterm birth prevention: a systematic review and meta-analysis by drug route.

scientific article published on 27 March 2013

Progestogens for preterm birth prevention: a systematic review and meta-analysis.

scientific article published on October 2012

Prospective Cohort Study of Uterine Fibroids and Miscarriage Risk

scientific article published on 7 June 2017

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 22 December 2017

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

scholarly article published in Nature Genetics

Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

erratum

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 01 July 2019

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article published on 16 March 2018

Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

scientific article

Publisher Correction: Shared heritability and functional enrichment across six solid cancers

scientific article published on 23 September 2019

Race/Ethnicity and the Pharmacogenetics of Reported Suicidality With Efavirenz Among Clinical Trials Participants.

scientific article published on September 2017

Racial differences in risk of spontaneous abortions associated with periconceptional over-the-counter nonsteroidal anti-inflammatory drug exposure

scientific article

Racial disparity in maternal-fetal genetic epistasis in spontaneous preterm birth

scientific article published on 01 June 2008

Racial disparity in pathophysiologic pathways of preterm birth based on genetic variants

scientific article published in 2009

Rare and low-frequency coding variants alter human adult height

scientific article (publication date: February 2017)

Relationship between very low low-density lipoprotein cholesterol concentrations not due to statin therapy and risk of type 2 diabetes: A US-based cross-sectional observational study using electronic health records

scientific article published on 28 August 2018

Report on the 6th African Society of Human Genetics (AfSHG) Meeting, March 12-15, 2009, Yaounde, Cameroon

scientific article (publication date: August 2010)

Risk of miscarriage among black women and white women in a U.S. Prospective Cohort Study

scientific article published on 4 April 2013

Shared heritability and functional enrichment across six solid cancers

scientific article published in Nature Communications

Shared heritability and functional enrichment across six solid cancers

Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.

scientific article

Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants

scientific article

Successful aging shows linkage to chromosomes 6, 7, and 14 in the Amish

scientific article published on July 2011

Synopsis of preterm birth genetic association studies: the preterm birth genetics knowledge base (PTBGene).

scientific article published on 20 May 2010

THE AUTHORS REPLY.

scientific article published in May 2018

The Gain-of-Function Integrin β3 Pro33 Variant Alters the Serotonin System in the Mouse Brain.

scientific article published on 16 October 2017

The Relationship between Total Fibroid Burden and First Trimester Bleeding and Pain

scientific article published on 3 November 2015

Toll-like receptor 1 polymorphisms increase susceptibility to candidemia.

scientific article published on February 2012

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

scientific article published on 21 December 2018

Transethnic and race-stratified genome-wide association study of fibroid characteristics in African American and European American women

Uterine leiomyomata and cesarean birth risk: a prospective cohort with standardized imaging.

scientific article

Validation of maternal recall of early pregnancy medication exposure using prospective diary data

scientific article

Variants in BET1L and TNRC6B associate with increasing fibroid volume and fibroid type among European Americans

scientific article published on 28 July 2013

Week-by-week alcohol consumption in early pregnancy and spontaneous abortion risk: A prospective cohort study

scientific article published on 13 July 2020

What Results Should Be Returned from Opportunistic Screening in Translational Research?

scientific article published on 01 March 2020

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