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List of works by Uwe Rix

A chemical and phosphoproteomic characterization of dasatinib action in lung cancer

scientific article

A computational approach to analyze the mechanism of action of the kinase inhibitor bafetinib

scientific article

A miniaturized chemical proteomic approach for target profiling of clinical kinase inhibitors in tumor biopsies

scientific article

A target-disease network model of second-generation BCR-ABL inhibitor action in Ph+ ALL

scientific article (publication date: 2013)

An immunoproteomic approach to characterize the CAR interactome and signalosome

scientific article published on 12 February 2019

An integrated chemical biology approach identifies specific vulnerability of Ewing's sarcoma to combined inhibition of Aurora kinases A and B.

scientific article published on 18 July 2011

Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets

scientific article published on 24 August 2007

Comparison of Quantitative Mass Spectrometry Platforms for Monitoring Kinase ATP Probe Uptake in Lung Cancer.

scientific article published on 22 November 2017

Dual Targeting of WEE1 and PLK1 by AZD1775 Elicits Single Agent Cellular Anticancer Activity.

scientific article published on 30 May 2017

Functional Proteomics and Deep Network Interrogation Reveal a Complex Mechanism of Action of Midostaurin in Lung Cancer Cells

scientific article published on 14 September 2018

Identification of kinase inhibitor targets in the lung cancer microenvironment by chemical and phosphoproteomics

scientific article

MASPECTRAS 2: An integration and analysis platform for proteomic data.

scientific article

Nilotinib-induced vasculopathy: identification of vascular endothelial cells as a primary target site.

scientific article published on 31 July 2017

Off-target based drug repurposing opportunities for tivantinib in acute myeloid leukemia

scientific article published in Scientific Reports

Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms

scientific article

Polypharmacology-based ceritinib repurposing using integrated functional proteomics

scientific article

Systems biology analysis of protein-drug interactions.

scientific article published on 27 December 2011

Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML.

scientific article

TRK xDFG mutations trigger a sensitivity switch from type I to II kinase inhibitors

scientific article published on 01 October 2020

Targeting a cell state common to triple-negative breast cancers

scientific article

The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib

scholarly article

Unraveling the rewired network

scientific article published on 01 August 2018

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