List of works by Georges Leclercq

A Murine Intestinal Intraepithelial NKp46-Negative Innate Lymphoid Cell Population Characterized by Group 1 Properties.

scientific article published on May 2017

Abundant stage-dependent Ly49E expression by liver NK cells is not essential for their differentiation and function

scientific article

Antigen receptor-redirected T cells derived from hematopoietic precursor cells lack expression of the endogenous TCR/CD3 receptor and exhibit specific antitumor capacities

scientific article published on 19 January 2017

CD27-deficient mice show normal NK-cell differentiation but impaired function upon stimulation

scientific article published in February 2011

Contribution of the Ly49E natural killer receptor in the immune response to Plasmodium berghei infection and control of hepatic parasite development

scientific article published on 30 January 2014

Differential Ly49e expression pathways in resting versus TCR-activated intraepithelial γδ T cells

scientific article

Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development

scientific article published on 07 April 2020

Distinct and temporary-restricted epigenetic mechanisms regulate human αβ and γδ T cell development

scientific article published on 27 July 2020

Expression of the inhibitory Ly49E receptor is not critically involved in the immune response against cutaneous, pulmonary or liver tumours.

scientific article published on 29 July 2016

GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate

scientific article published on 6 April 2016

HES1 and HES4 have non-redundant roles downstream of Notch during early human T cell development

scientific article published on 09 January 2020

Human Thymic CD10+ PD-1+ Intraepithelial Lymphocyte Precursors Acquire Interleukin-15 Responsiveness at the CD1a- CD95+ CD28- CCR7- Developmental Stage

scientific article published on 20 November 2020

In vitro generation of immune cells from pluripotent stem cells

scientific article published on January 2011

In vitro generation of mature, naive antigen-specific CD8(+) T cells with a single T-cell receptor by agonist selection

scientific article published on 4 October 2013

In vitro human embryonic stem cell hematopoiesis mimics MYB-independent yolk sac hematopoiesis

scientific article published on 7 November 2014

Inhibitory receptors specific for MHC class I educate murine NK cells but not CD8αα intestinal intraepithelial T lymphocytes

scientific article

Integrated scRNA-Seq Identifies Human Postnatal Thymus Seeding Progenitors and Regulatory Dynamics of Differentiating Immature Thymocytes

scientific article published on 13 April 2020

Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions

scientific article published on 3 March 2011

Ly49E expression on CD8αα-expressing intestinal intraepithelial lymphocytes plays no detectable role in the development and progression of experimentally induced inflammatory bowel diseases

scientific article

NKT sublineage specification and survival requires the ubiquitin-modifying enzyme TNFAIP3/A20.

scientific article published on 22 August 2016

Notch induces human T-cell receptor γδ+ thymocytes to differentiate along a parallel, highly proliferative and bipotent CD4 CD8 double-positive pathway.

scientific article published on 4 November 2011

Notch3 activation is sufficient but not required for inducing human T-lineage specification

scientific article published on 7 November 2014

RHAMM/HMMR (CD168) is not an ideal target antigen for immunotherapy of acute myeloid leukemia

scientific article

Rapid and Effective Generation of Nanobody Based CARs using PCR and Gibson Assembly

scientific article published on 30 January 2020

Regulatory Role for NK Cells in a Mouse Model of Systemic Juvenile Idiopathic Arthritis

scientific article published on 01 November 2019

Specific Notch receptor-ligand interactions control human TCR-αβ/γδ development by inducing differential Notch signal strength.

scientific article published on 25 March 2013

T-cells with a single tumor antigen-specific T-cell receptor can be generated in vitro from clinically relevant stem cell sources

scientific article published on 17 February 2020

The Ly49E Receptor Inhibits the Immune Control of Acute Trypanosoma cruzi Infection.

scientific article

The checkpoint for agonist selection precedes conventional selection in human thymus.

scientific article published on February 2017

The role of Ly49E receptor expression on murine intraepithelial lymphocytes in intestinal cancer development and progression.

scientific article

The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation

scientific article published on 29 April 2020

Treatment of a patient with severe cytomegalovirus (CMV) infection after haploidentical stem cell transplantation with donor-derived CMV-specific T cells

scientific article published on 14 April 2020

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