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List of works by Edward P O'Brien

A chemical kinetic basis for measuring translation initiation and elongation rates from ribosome profiling data.

scientific article published on 23 May 2019

A pan-CRISPR analysis of mammalian cell specificity identifies ultra-compact sgRNA subsets for genome-scale experiments

scientific article published on 02 February 2022

Cocktail of REGN Antibodies Binds More Strongly to SARS-CoV-2 Than Its Components, but the Omicron Variant Reduces Its Neutralizing Ability

scientific article published on 11 April 2022

Electrostatic Interactions Explain the Higher Binding Affinity of the CR3022 Antibody for SARS-CoV-2 than the 4A8 Antibody

scientific article published on 06 July 2021

Electrostatic Interactions Govern Extreme Nascent Protein Ejection Times from Ribosomes and Can Delay Ribosome Recycling

scientific article published on 23 March 2020

Hierarchical Markov State Model Building to Describe Molecular Processes

scientific article published on 17 February 2020

Increasing Protein Production Rates Can Decrease the Rate at Which Functional Protein Is Produced and Their Steady-State Levels.

scientific article published on 26 June 2017

It is theoretically possible to avoid misfolding into non-covalent lasso entanglements using small molecule drugs

scientific article published on 12 March 2024

Mechanochemistry in Translation

scientific article published on 11 June 2019

Origins of the Mechanochemical Coupling of Peptide Bond Formation to Protein Synthesis.

scientific article published on 26 March 2018

Ribosome Elongation Kinetics of Consecutively Charged Residues Are Coupled to Electrostatic Force

scientific article published on 15 October 2021

Structural Origins of FRET-Observed Nascent Chain Compaction on the Ribosome

scientific article published on 18 October 2018

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