List of works - Thierry Léveillard

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

scientific article published on 21 December 2015

Bgl I reveals two polymorphic sites in the human inter-alpha-trypsin inhibitor heavy chain gene ITI H2 ⬇️

scientific article published on January 25, 1990

CRB1 mutations in inherited retinal dystrophies

scientific article published on 27 December 2011

Cell Signaling with Extracellular Thioredoxin and Thioredoxin-Like Proteins: Insight into Their Mechanisms of Action

scientific article published on 12 September 2017

Development and application of a next-generation-sequencing (NGS) approach to detect known and novel gene defects underlying retinal diseases

scientific article

Differential proteomic analysis of the mouse retina: the induction of crystallin proteins by retinal degeneration in the rd1 mouse

scientific article

Does GDNF exert its neuroprotective effects on photoreceptors in the rd1 retina through the glial glutamate transporter GLAST?

scientific article

Expression of rod-derived cone viability factor: dual role of CRX in regulating promoter activity and cell-type specificity

scientific article (publication date: 7 October 2010)

Functional cone rescue by RdCVF protein in a dominant model of retinitis pigmentosa

scientific article

Functional rescue of cone photoreceptors in retinitis pigmentosa

scientific article published on July 2013

Gene therapy in ophthalmology: validation on cultured retinal cells and explants from postmortem human eyes

scientific article published on 26 February 2011

Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3

scientific article

Genotypic and phenotypic characterization of P23H line 1 rat model

scientific article published on 26 May 2015

Identification and characterization of rod-derived cone viability factor

scientific article

Identification of an Alternative Splicing Product of the Otx2 Gene Expressed in the Neural Retina and Retinal Pigmented Epithelial Cells

scientific article

Inherited retinal degenerations: therapeutic prospects

scientific article published on May 2004

La transplantation de photorécepteurs immatures

scientific article published on 01 March 2007

MDM2 expression during mouse embryogenesis and the requirement of p53 ⬇️

scientific article published on June 1, 1998

Mathematical Model of the Role of RdCVF in the Coexistence of Rods and Cones in a Healthy Eye.

scientific article

Metabolic and redox signaling in the retina.

scientific article

Neuroprotection of photoreceptor cells in rod-cone dystrophies: from cell therapy to cell signalling

scientific article

Normal retina releases a diffusible factor stimulating cone survival in the retinal degeneration mouse ⬇️

scientific article published on July 7, 1998

Nxnl2 splicing results in dual functions in neuronal cell survival and maintenance of cell integrity

scientific journal article

Partial characterization of retina-derived cone neuroprotection in two culture models of photoreceptor degeneration.

scientific article published on February 2003

PromAn: an integrated knowledge-based web server dedicated to promoter analysis

scientific article

Rare and common variants in extracellular matrix gene Fibrillin 2 (FBN2) are associated with macular degeneration

scientific article

Retinal degenerations: from cell signaling to cell therapy; pre-clinical and clinical issues

scientific article published on April 2007

Rhodopsin maturation defects induce photoreceptor death by apoptosis: a fly model for RhodopsinPro23His human retinitis pigmentosa

scientific article published on 27 July 2005

Rod-derived cone viability factor : un espoir de thérapie des dégénérescences rétiniennes ?

scientific article published on 01 January 2005

Rod-derived cone viability factor for treating blinding diseases: from clinic to redox signaling

scientific article

Rod-derived cone viability factor promotes cone survival by stimulating aerobic glycolysis

scientific article

Seven new loci associated with age-related macular degeneration

scientific article

TRPM1 is mutated in patients with autosomal-recessive complete congenital stationary night blindness

scientific article

Taurine provides neuroprotection against retinal ganglion cell degeneration

scientific article

The MDM2 C-terminal Region Binds to TAFII250 and Is Required for MDM2 Regulation of the Cyclin A Promoter ⬇️

scientific article published on December 5, 1997

The Thioredoxin Encoded by the Rod-Derived Cone Viability Factor Gene Protects Cone Photoreceptors Against Oxidative Stress

scientific article published on 29 March 2016

The familial dementia gene revisited: a missense mutation revealed by whole-exome sequencing identifies ITM2B as a candidate gene underlying a novel autosomal dominant retinal dystrophy in a large family.

scientific article

The homeobox gene CHX10/VSX2 regulates RdCVF promoter activity in the inner retina

scientific article

The metabolic signaling of the nucleoredoxin-like 2 gene supports brain function

scientific article published on 25 November 2021

The search for rod-dependent cone viability factors, secreted factors promoting cone viability.

scientific article published in January 2004

Therapeutic strategy for handling inherited retinal degenerations in a gene-independent manner using rod-derived cone viability factors

scientific article published on 20 February 2014

Transcriptomic analysis of human retinal detachment reveals both inflammatory response and photoreceptor death

scientific article published in 2011

Transcriptomic analysis of human retinal surgical specimens using jouRNAI

scientific article published on 14 August 2013

Transplantation of photoreceptor and total neural retina preserves cone function in P23H rhodopsin transgenic rat.

scientific article

Vibratome sectioning mouse retina to prepare photoreceptor cultures

scientific article published on 22 December 2014

Viral-mediated RdCVF and RdCVFL expression protects cone and rod photoreceptors in retinal degeneration

scientific article

Whole-Exome Sequencing Identifies Mutations in GPR179 Leading to Autosomal-Recessive Complete Congenital Stationary Night Blindness

scientific article published in July 2012

Whole-exome sequencing identifies KIZ as a ciliary gene associated with autosomal-recessive rod-cone dystrophy

scientific article

Whole-exome sequencing identifies mutations in GPR179 leading to autosomal-recessive complete congenital stationary night blindness

scientific article

[Altruism in the retina: sticks feed cones].

scientific article published on 19 October 2015

℮-conome: an automated tissue counting platform of cone photoreceptors for rodent models of retinitis pigmentosa

scientific article

List of works by Thierry Léveillard

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

Bgl I reveals two polymorphic sites in the human inter-alpha-trypsin inhibitor heavy chain gene ITI H2 ⬇️

CRB1 mutations in inherited retinal dystrophies

Cell Signaling with Extracellular Thioredoxin and Thioredoxin-Like Proteins: Insight into Their Mechanisms of Action

Development and application of a next-generation-sequencing (NGS) approach to detect known and novel gene defects underlying retinal diseases

Differential proteomic analysis of the mouse retina: the induction of crystallin proteins by retinal degeneration in the rd1 mouse

Does GDNF exert its neuroprotective effects on photoreceptors in the rd1 retina through the glial glutamate transporter GLAST?

Expression of rod-derived cone viability factor: dual role of CRX in regulating promoter activity and cell-type specificity

Functional cone rescue by RdCVF protein in a dominant model of retinitis pigmentosa

Functional rescue of cone photoreceptors in retinitis pigmentosa

Gene therapy in ophthalmology: validation on cultured retinal cells and explants from postmortem human eyes

Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3

Genotypic and phenotypic characterization of P23H line 1 rat model

Identification and characterization of rod-derived cone viability factor

Identification of an Alternative Splicing Product of the Otx2 Gene Expressed in the Neural Retina and Retinal Pigmented Epithelial Cells

Inherited retinal degenerations: therapeutic prospects

La transplantation de photorécepteurs immatures

MDM2 expression during mouse embryogenesis and the requirement of p53 ⬇️

Mathematical Model of the Role of RdCVF in the Coexistence of Rods and Cones in a Healthy Eye.

Metabolic and redox signaling in the retina.

Neuroprotection of photoreceptor cells in rod-cone dystrophies: from cell therapy to cell signalling

Normal retina releases a diffusible factor stimulating cone survival in the retinal degeneration mouse ⬇️

Nxnl2 splicing results in dual functions in neuronal cell survival and maintenance of cell integrity

Partial characterization of retina-derived cone neuroprotection in two culture models of photoreceptor degeneration.

PromAn: an integrated knowledge-based web server dedicated to promoter analysis

Rare and common variants in extracellular matrix gene Fibrillin 2 (FBN2) are associated with macular degeneration

Retinal degenerations: from cell signaling to cell therapy; pre-clinical and clinical issues

Rhodopsin maturation defects induce photoreceptor death by apoptosis: a fly model for RhodopsinPro23His human retinitis pigmentosa

Rod-derived cone viability factor : un espoir de thérapie des dégénérescences rétiniennes ?

Rod-derived cone viability factor for treating blinding diseases: from clinic to redox signaling

Rod-derived cone viability factor promotes cone survival by stimulating aerobic glycolysis

Seven new loci associated with age-related macular degeneration

TRPM1 is mutated in patients with autosomal-recessive complete congenital stationary night blindness

Taurine provides neuroprotection against retinal ganglion cell degeneration

The MDM2 C-terminal Region Binds to TAFII250 and Is Required for MDM2 Regulation of the Cyclin A Promoter ⬇️

The Thioredoxin Encoded by the Rod-Derived Cone Viability Factor Gene Protects Cone Photoreceptors Against Oxidative Stress

The familial dementia gene revisited: a missense mutation revealed by whole-exome sequencing identifies ITM2B as a candidate gene underlying a novel autosomal dominant retinal dystrophy in a large family.

The homeobox gene CHX10/VSX2 regulates RdCVF promoter activity in the inner retina

The metabolic signaling of the nucleoredoxin-like 2 gene supports brain function

The search for rod-dependent cone viability factors, secreted factors promoting cone viability.

Therapeutic strategy for handling inherited retinal degenerations in a gene-independent manner using rod-derived cone viability factors

Transcriptomic analysis of human retinal detachment reveals both inflammatory response and photoreceptor death

Transcriptomic analysis of human retinal surgical specimens using jouRNAI

Transplantation of photoreceptor and total neural retina preserves cone function in P23H rhodopsin transgenic rat.

Vibratome sectioning mouse retina to prepare photoreceptor cultures

Viral-mediated RdCVF and RdCVFL expression protects cone and rod photoreceptors in retinal degeneration

Whole-Exome Sequencing Identifies Mutations in GPR179 Leading to Autosomal-Recessive Complete Congenital Stationary Night Blindness

Whole-exome sequencing identifies KIZ as a ciliary gene associated with autosomal-recessive rod-cone dystrophy

Whole-exome sequencing identifies mutations in GPR179 leading to autosomal-recessive complete congenital stationary night blindness

[Altruism in the retina: sticks feed cones].

℮-conome: an automated tissue counting platform of cone photoreceptors for rodent models of retinitis pigmentosa