List of works by Leon Terstappen

A comparison of breast cancer tumor cells with varying expression of the Her2/neu receptor by Raman microspectroscopic imaging

scientific article published on 27 October 2010

A microwell array platform to print and measure biomolecules produced by single cells

scientific article published on 01 May 2019

A novel side electrode configuration integrated in fused silica microsystems for synchronous optical and electrical spectroscopy.

scientific article published on 23 April 2014

A single platform image cytometer for resource-poor settings to monitor disease progression in HIV infection

scientific article published in March 2007

All circulating EpCAM+CK+CD45- objects predict overall survival in castration-resistant prostate cancer.

scientific article published on 10 February 2010

All-printed cell counting chambers with on-chip sample preparation for point-of-care CD4 counting

scientific article published on 03 July 2018

An immunomagnetic single-platform image cytometer for cell enumeration based on antibody specificity

scientific article published on 7 February 2007

Analysis of Released Circulating Tumor Cells During Surgery for Non-Small Cell Lung Cancer

scientific article published on 26 November 2019

Analysis of cell surface antigens by Surface Plasmon Resonance imaging

scientific article published on 27 August 2013

Androgen receptor expression in circulating tumour cells from castration-resistant prostate cancer patients treated with novel endocrine agents.

scientific article

Apoptosis of circulating tumor cells in prostate cancer patients

scientific article

Automated identification of circulating tumor cells by image cytometry

scientific article

CCR 20th Anniversary Commentary: Circulating Tumor Cells in Prostate Cancer.

scientific article published in November 2015

CCR 20th Anniversary Commentary: Paving the Way for Circulating Tumor Cells.

scientific article published in July 2015

CD4 and CD8 enumeration for HIV monitoring in resource-constrained settings

scientific article published in March 2009

CD4+ T lymphocytes enumeration by an easy-to-use single platform image cytometer for HIV monitoring in resource-constrained settings

scientific article published in September 2007

CTC Technologies and Tools

scientific article published on 13 December 2018

Cancer Stem Cells, Epithelial to Mesenchymal Markers, and Circulating Tumor Cells in Small Cell Lung Cancer.

scientific article published on 8 June 2016

Cancer-ID: Toward Identification of Cancer by Tumor-Derived Extracellular Vesicles in Blood

scientific article published on 04 June 2020

Capture of Tumor Cells on Anti-EpCAM-Functionalized Poly(acrylic acid)-Coated Surfaces.

scientific article published on 17 May 2016

Cell analysis system based on compact disk technology

scientific article

CellTracks TDI: an image cytometer for cell characterization

scientific article

Challenges for CTC-based liquid biopsies: low CTC frequency and diagnostic leukapheresis as a potential solution

scientific article

Challenges in circulating tumor cell detection by the CellSearch system

scientific article

Challenges in the enumeration and phenotyping of CTC.

scientific article

Changes in the growth properties of CD34+, CD38- bone marrow progenitors during human fetal development

scientific article published on 01 July 1995

Characterization of ERG, AR and PTEN gene status in circulating tumor cells from patients with castration-resistant prostate cancer.

scientific article

Characterization of circulating tumor cells by fluorescence in situ hybridization

scientific article published on 01 June 2009

Circulating Tumor Cell Analysis in Patients with Progressive Castration-Resistant Prostate Cancer

scientific article published on 01 April 2007

Circulating Tumor Cells Count and Morphological Features in Breast, Colorectal and Prostate Cancer.

scientific article

Circulating cancer cells and their clinical applications.

scientific article published on 17 May 2011

Circulating endothelial cells, circulating tumour cells, tissue factor, endothelin-1 and overall survival in prostate cancer patients treated with docetaxel

scientific article published in July 2010

Circulating melanoma cells and survival in metastatic melanoma

scientific article published on 03 January 2011

Circulating tumor cells before and during follow-up after breast cancer surgery

scientific article published on 06 October 2014

Circulating tumor cells in advanced non-small cell lung cancer patients are associated with worse tumor response to checkpoint inhibitors

scientific article published on 10 July 2019

Circulating tumor cells in lung cancer are prognostic and predictive for worse tumor response in both targeted- and chemotherapy

scientific article published on 01 December 2019

Circulating tumor cells in patients with breast cancer dormancy

scientific article published on 01 December 2004

Circulating tumor cells in small-cell lung cancer: a predictive and prognostic factor

article by T. J. N. Hiltermann et al published 11 June 2012 in Annals of Oncology

Circulating tumor cells predict survival in patients with metastatic prostate cancer

scientific article published on 01 April 2005

Circulating tumor cells versus imaging--predicting overall survival in metastatic breast cancer.

scientific article published in November 2006

Circulating tumor cells, disease recurrence and survival in newly diagnosed breast cancer

scientific article

Circulating tumor cells, tumor-derived extracellular vesicles and plasma cytokeratins in castration-resistant prostate cancer patients.

scientific article published on 10 April 2018

Circulating tumor cells: a novel prognostic factor for newly diagnosed metastatic breast cancer

scientific article

Circulating tumour cell (CTC) counts as intermediate end points in castration-resistant prostate cancer (CRPC): a single-centre experience

scientific article

Circulating tumour cell increase as a biomarker of disease progression in metastatic castration-resistant prostate cancer patients with low baseline CTC counts

scientific article published on 01 July 2018

Circulating tumour cells early predict progression-free and overall survival in advanced colorectal cancer patients treated with chemotherapy and targeted agents.

scientific article published on 27 October 2009

Classification of Cells in CTC-Enriched Samples by Advanced Image Analysis

scientific article published on 10 October 2018

Clinical evaluation of a simple image cytometer for CD4 enumeration on HIV-infected patients

scientific article published in January 2010

Comparing circulating tumor cell counts with dynamic tumor size changes as predictor of overall survival - a quantitative modeling framework

scientific article published on 11 June 2020

Comparison of two methods for enumerating circulating tumor cells in carcinoma patients

scientific article published on 01 November 2005

Consensus Statement on Circulating Biomarkers for Advanced Prostate Cancer

scientific article published on 15 May 2018

Construction of repeat-free fluorescence in situ hybridization probes

scientific article

Controlled antibody release from gelatin for on-chip sample preparation

scientific article published on 14 April 2016

Coordinate expression of β1 and β2 integrin “activation” epitopes during T cell responses in secondary lymphoid tissue ⬇️

scientific article published on 01 November 1993

Correlation between circulating endothelial cell counts and plasma thrombomodulin levels as markers for endothelial damage.

scientific article

DNA Detection by Flow Cytometry using PNA-Modified Metal-Organic Framework Particles

scientific article

Decline in Circulating Tumor Cell Count and Treatment Outcome in Advanced Prostate Cancer

scientific article published on 8 June 2016

Defining the dimensions of Circulating Tumor Cells in a large series of breast, prostate, colon, and bladder cancer patients ⬇️

scientific article published on 18 September 2020

Detecting Blood-Based Biomarkers in Metastatic Breast Cancer: A Systematic Review of Their Current Status and Clinical Utility

scientific article

Detection and Characterization of Circulating Tumor Cells by the CellSearch Approach

scientific article published on January 2015

Detection of Circulating Tumor Cells in the Diagnostic Leukapheresis Product of Non-Small-Cell Lung Cancer Patients Comparing CellSearch® and ISET

scientific article published on 07 April 2020

Detection of cancer before distant metastasis

scientific article

Detection of circulating tumor cells

scientific article

Detection of extracellular vesicles in plasma and urine of prostate cancer patients by flow cytometry and surface plasmon resonance imaging

scientific article published on 04 June 2020

Distinguishing septic from normal donors by detection of sPLA2-IIA from human plasma using a microsieve-based immunoassay

scientific article published on 19 April 2017

EPAC-Lung: Pooled analysis of circulating tumor cells in advanced non-small cell lung cancer

scientific article published on 01 April 2019

EPAC-lung: pooled analysis of circulating tumour cells in advanced non-small cell lung cancer

scientific article published on 27 June 2019

Endothelial cells in peripheral blood of healthy subjects and patients with metastatic carcinomas

scientific article published on 01 February 2007

Endothelium-Derived Extracellular Vesicles Associate with Poor Prognosis in Metastatic Colorectal Cancer

scientific article published on 15 December 2020

Evidence on the cost of breast cancer drugs is required for rational decision making.

scientific article

Expression of epithelial cell adhesion molecule in carcinoma cells present in blood and primary and metastatic tumors

scientific article published on July 2005

Feasibility of a simple microsieve-based immunoassay platform

scientific article published on 20 July 2016

Filter characteristics influencing circulating tumor cell enrichment from whole blood

scientific article

Filtration parameters influencing circulating tumor cell enrichment from whole blood

scientific article

Flat-top illumination profile in an epifluorescence microscope by dual microlens arrays

scientific article

Genetic characterization of a unique neuroendocrine transdifferentiation prostate circulating tumor cell-derived eXplant model

scientific article published on 20 April 2020

Genome-wide association study of cardiovascular disease in testicular cancer patients treated with platinum-based chemotherapy

scientific article published on 03 October 2020

Global gene expression profiling of circulating endothelial cells in patients with metastatic carcinomas.

scientific article

Global gene expression profiling of circulating tumor cells.

scientific article

HER-2 gene amplification can be acquired as breast cancer progresses

scientific article

Health economic impact of liquid biopsies in cancer management

article

How to Agree on a CTC: Evaluating the Consensus in Circulating Tumor Cell Scoring

scientific article published on 24 September 2018

Imaging technique implemented in CellTracks system

scientific article

Immuno-capture of extracellular vesicles for individual multi-modal characterization using AFM, SEM and Raman spectroscopy

scientific article published on 01 July 2019

Immunomagnetic separation technologies

scientific article published on January 2012

Importance of circulating tumor cells in newly diagnosed colorectal cancer.

scientific article

Improving the CellSearch® system

scientific article published on 31 October 2016

International study on inter-reader variability for circulating tumor cells in breast cancer

scientific article

Interpolation method for accurate affinity ranking of arrayed ligand-analyte interactions

scientific article published on 13 February 2016

Interrogating Metastatic Prostate Cancer Treatment Switch Decisions: A Multi-institutional Survey

scientific article published on 10 October 2016

Isolation and characterization of circulating tumor cells in patients with metastatic colorectal cancer

scientific article

Isolation of single cells for protein therapeutics using microwell selection and Surface Plasmon Resonance imaging.

scientific article published on 22 May 2017

Label-Free Prostate Cancer Detection by Characterization of Extracellular Vesicles Using Raman Spectroscopy

scientific article published on 10 September 2018

Label-free cell profiling

scientific article published on 11 April 2013

Label-free identification and chemical characterisation of single extracellular vesicles and lipoproteins by synchronous Rayleigh and Raman scattering

scientific article published on 19 February 2020

Label-free imaging and identification of typical cells of acute myeloid leukaemia and myelodysplastic syndrome by Raman microspectroscopy.

scientific article published on February 2015

Leukocyte-Derived Extracellular Vesicles in Blood with and without EpCAM Enrichment

scientific article published on 20 August 2019

Magnetic Particles for CTC Enrichment

scientific article published on 26 November 2020

Magnetic field design for selecting and aligning immunomagnetic labeled cells.

scientific article published in March 2002

Microfluidic device for DNA amplification of single cancer cells isolated from whole blood by self-seeding microwells

scientific article published on 24 September 2015

Microsieves for the detection of circulating tumor cells in leukapheresis product in non-small cell lung cancer patients

scientific article published on 01 August 2020

Mobilization and purification of CD34+ cells from normal donors-regimens with G-CSF, GM-CSF, or a combination of both

scientific article published on 01 March 1996

Modeling single cell antibody excretion on a biosensor

scientific article published on 31 March 2016

Monitoring expression of HER-2 on circulating epithelial cells in patients with advanced breast cancer

scientific article published on 01 November 2002

Multigene reverse transcription-PCR profiling of circulating tumor cells in hormone-refractory prostate cancer

scientific article published on 26 February 2004

Multiplex Label Free Characterization of Cancer Cell Lines Using Surface Plasmon Resonance Imaging

scientific article published on 27 May 2019

On-chip sample preparation by controlled release of antibodies for simple CD4 counting.

scientific article published on 3 November 2011

Organosilicon uptake by biological membranes

scientific article published on 09 June 2021

Parallel probing of drug uptake of single cancer cells on a microfluidic device

scientific article

Parallel single cancer cell whole genome amplification using button-valve assisted mixing in nanoliter chambers

scientific article

Physiological stress induces the metastasis marker AGR2 in breast cancer cells

scientific article published on 11 August 2007

Platelet removal by single-step centrifugation

scientific article published on 17 June 2020

Pooled Analysis of the Prognostic Relevance of Circulating Tumor Cells in Primary Breast Cancer

scientific article published on 5 January 2016

Potential Applications for Circulating Tumor Cells Expressing the Insulin-Like Growth Factor-I Receptor

article

Prognostic significance of circulating tumor cells in patients with metastatic colorectal cancer

scientific article published on 12 March 2009

Programmable v-type valve for cell and particle manipulation in microfluidic devices

scientific article published on 9 December 2015

Quality of extracellular vesicle images by transmission electron microscopy is operator and protocol dependent

article

Quantification of antibody production of individual hybridoma cells by surface plasmon resonance imaging.

scientific article

Quantifying HER-2 expression on circulating tumor cells by ACCEPT.

scientific article published on 30 October 2017

Quantitative detection of gold nanoparticles on individual, unstained cancer cells by scanning electron microscopy

scientific article

Rapid selection of cell subpopulation-specific human monoclonal antibodies from a synthetic phage antibody library

scientific article

Rate zonal centrifugation can partially separate platelets from platelet-derived vesicles

scientific article published on 10 July 2020

Re: Anti-epithelial cell adhesion molecule antibodies and the detection of circulating normal-like breast tumor cells

Real-world data on discordance between estrogen, progesterone, and HER2 receptor expression on diagnostic tumor biopsy versus tumor resection material.

scientific article published on 13 February 2019

Reconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patterns

scientific article published on 01 July 2021

Relationship of circulating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic colorectal cancer

scientific article

SEM-Raman image cytometry of cells

scientific article published on 01 September 2018

Sample Preparation Methods Following CellSearch Approach Compatible of Single-Cell Whole-Genome Amplification: An Overview

scientific article published on January 2015

Scanning Electron Microscopy of Circulating Tumor Cells and Tumor-Derived Extracellular Vesicles

scientific article published on 31 October 2018

Self-Seeding Microwells to Isolate and Assess the Viability of Single Circulating Tumor Cells ⬇️

scientific article published on 23 January 2019

Self-seeding microwell chip for the isolation and characterization of single cells

scientific article

Significance of Circulating Tumor Cells Detected by the CellSearch System in Patients with Metastatic Breast Colorectal and Prostate Cancer

scientific article

Significant and sustained antitumor activity in post-docetaxel, castration-resistant prostate cancer with the CYP17 inhibitor abiraterone acetate

scientific article

Single tube liquid biopsy for advanced non-small cell lung cancer

scientific article published on 28 January 2019

Single-Cell Analyses of Prostate Cancer Liquid Biopsies Acquired by Apheresis

scientific article published on 09 August 2018

Statistical considerations for enumeration of circulating tumor cells

Surface Plasmon Resonance is an Analytically Sensitive Method for Antigen Profiling of Extracellular Vesicles.

scientific article published on 7 August 2017

Synchronized Rayleigh and Raman scattering for the characterization of single optically trapped extracellular vesicles

scientific article published on 24 October 2019

Temperature-Switch Cytometry-Releasing Antibody on Demand from Inkjet-Printed Gelatin for On-Chip Immunostaining

scientific article published on 29 September 2016

The "common stem cell" hypothesis reevaluated: human fetal bone marrow contains separate populations of hematopoietic and stromal progenitors

scientific article published on May 1995

The detection of EpCAM(+) and EpCAM(-) circulating tumor cells.

scientific article published on 17 July 2015

The predictive and prognostic value of circulating endothelial cells in advanced colorectal cancer patients receiving first-line chemotherapy and bevacizumab

scientific article published on 28 October 2010

Toward a real liquid biopsy in metastatic breast and prostate cancer: Diagnostic LeukApheresis increases CTC yields in a European prospective multicenter study (CTCTrap)

scientific article published on 19 September 2018

Towards the Biological Understanding of CTC: Capture Technologies, Definitions and Potential to Create Metastasis

scientific article

Trends in SPR Cytometry: Advances in Label-Free Detection of Cell Parameters

scientific article published on 30 October 2018

Tumor cell capture from blood by flowing across antibody-coated surfaces

scientific article published on 01 March 2019

Tumor cells circulate in the peripheral blood of all major carcinomas but not in healthy subjects or patients with nonmalignant diseases

scientific article

Tumour-derived extracellular vesicles in blood of metastatic cancer patients associate with overall survival

scientific article published on 15 January 2020

Unbiased and automated identification of a circulating tumour cell definition that associates with overall survival

scientific article (publication date: 2011)

Unbiased quantitative assessment of Her-2 expression of circulating tumor cells in patients with metastatic and non-metastatic breast cancer

scientific article published on 27 December 2012

uPAR and HER-2 gene status in individual breast cancer cells from blood and tissues

scholarly article

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